Neurology
Brain fog can persist for months after COVID diagnosis.
28 Oct, 2021 | 10:13h | UTCAssessment of Cognitive Function in Patients After COVID-19 Infection – JAMA Network Open
Commentaries:
Brain fog can persist 8 months after COVID diagnosis – CIDRAP
RCT: Extended follow-up of local steroid injection for carpal tunnel syndrome.
28 Oct, 2021 | 09:46h | UTC
Commentary on Twitter
In carpal tunnel syndrome, this randomized trial of local steroid vs placebo injection shows similar symptom severity score improvement but a significant small reduction in rate of and longer time to surgery after steroid. @IsamAtroshi @jonasranstam https://t.co/s5LibRnFaV
— JAMA Network Open (@JAMANetworkOpen) October 22, 2021
Infection with Covid-19 carries a much higher risk of developing neurological complications than Covid-19 vaccines.
26 Oct, 2021 | 02:04h | UTCOriginal Study: Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection – Nature Medicine
Commentaries:
Covid: Vaccine study links virus to rare neurological illness – BBC
Commentary on Twitter
A study in @NatureMedicine finds there is an increased risk of neurological complications in those who received COVID-19 vaccines, but the risk of these complications is greater following a positive SARS-CoV-2 test. https://t.co/WKnFa9InbL pic.twitter.com/xir6U3JhL8
— Nature Portfolio (@NaturePortfolio) October 25, 2021
RCT: Mirtazapine not better than placebo for the treatment of agitation in people with dementia and was possibly associated with increased mortality (7 vs.1 deaths, difference not statistically significant; p=0·065).
22 Oct, 2021 | 10:19h | UTCCommentary: Common antidepressant should no longer be used to treat people with dementia – University of Exeter
Large observational study suggests Tramadol is associated with increased risk of adverse outcomes compared to Codeine.
20 Oct, 2021 | 10:11h | UTCAssociation of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Clinical Outcomes – JAMA (free for a limited period)
Editorial: Tramadol, Codeine, and Risk of Adverse Outcomes – JAMA (free for a limited period)
Cohort study: Acute urinary retention may be a clinical marker of occult prostate cancer and other urogenital, colorectal, and neurological cancers.
20 Oct, 2021 | 09:50h | UTCAcute urinary retention and risk of cancer: population based Danish cohort study – The BMJ
Commentary on Twitter
This study finds that a first diagnosis of acute urinary retention in patients aged 50 years or older was a clinical marker not only for prostate cancer but also for other urogenital cancers and colorectal and neurological cancershttps://t.co/0f1Z93cqR0 @dceaarhus
— The BMJ (@bmj_latest) October 19, 2021
Review: Stroke prevention after cryptogenic stroke.
19 Oct, 2021 | 08:46h | UTCStroke Prevention After Cryptogenic Stroke – Current Cardiology Reports
Related:
Canadian Stroke Best Practice Recommendations for Acute Stroke Management
Autoimmune encephalitis–related seizures and epilepsy: diagnostic and therapeutic approaches.
15 Oct, 2021 | 02:08h | UTC
Commentary on Twitter
Acute symptomatic seizure secondary to autoimmune encephalitis is a common symptom in patients with autoimmune encephalitis, particularly when the limbic system is involved.https://t.co/amUDoR8fXK pic.twitter.com/Fn0BFCbmhh
— Mayo Clinic Proceedings (@MayoProceedings) August 26, 2021
Intracerebral hemorrhage: diagnosis, emergency management, and prognosis.
15 Oct, 2021 | 02:12h | UTCIntracerebral Hemorrhage: Diagnosis, Emergency Management, and Prognosis – emDocs
M-A: Frequency of Neurologic Manifestations in COVID-19 – up to one-third of patients (89% hospitalized) experienced at least one neurological manifestation.
13 Oct, 2021 | 01:40h | UTC
M-A: New pharmacologic agents (Ditans and Gepants) are not as good as triptans for treating migraines.
13 Oct, 2021 | 01:17h | UTCCommentary: Migraine: Older Drugs May Be Best Bet for Lessening Pain – Physician’s Weekly
Commentary on Twitter
This systematic review and meta-analysis found that ditans and gepants were associated with less efficacy compared with triptans, whereas gepants were associated with fewer adverse events compared with triptans for migraine treatment. https://t.co/PFCHg4MZ8r
— JAMA Network Open (@JAMANetworkOpen) October 11, 2021
RCT: In patients with acute ischemic stroke and large vessel occlusion, thrombectomy with combined contact aspiration and stent retriever was not better than stent retriever alone.
12 Oct, 2021 | 00:04h | UTCEffect of Thrombectomy With Combined Contact Aspiration and Stent Retriever vs Stent Retriever Alone on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion: The ASTER2 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries:
Little Benefit From Adding Aspiration to Thrombectomy for Stroke – Medscape (free registration required)
Combo Thrombectomy Approach No Better for Large Vessel Strokes – MedPage Today (free registration required)
Commentary on Twitter
Clinical trial found the rate of near-total or total reperfusion at the end of the endovascular procedure was not significantly different for patients receiving thrombectomy with contact aspiration and stent retriever combined vs stent retriever alone https://t.co/SQTEnysFBG
— JAMA (@JAMA_current) September 28, 2021
RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.
11 Oct, 2021 | 23:58h | UTCNews release: Aerobic exercise after a sport-related concussion speeds recovery in adolescent athletes – University at Buffalo
Related:
Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion
RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.
Commentaries on Twitter
RCT study in @TheLancet shows adolescents who sub-threshold aerobic exercise 20 mins/ day for 4 weeks starting within 10 days of a concussion are 48% less likely to get prolonged symptoms. https://t.co/1tafsQHrXt
— Dr Ademola Adejuwon (@SmileySportyDoc) October 2, 2021
Sport-related #concussion is a major public health issue in US adolescents
This new RCT of aerobic exercise vs stretching found exercise sped up recovery and reduced risk for persistent post-concussive symptomshttps://t.co/jP30N1eJEQ pic.twitter.com/ux42VSMfSr
— The Lancet Child & Adolescent Health (@LancetChildAdol) October 1, 2021
Editorial: Brain health and its social determinants.
10 Oct, 2021 | 21:35h | UTCBrain health and its social determinants – The Lancet
Commentary on Twitter
Globally, action to tackle the social determinants of mental ill health—including poverty, racism, and discrimination—remains a low priority in too many countries.
On #WorldMentalHealthDay, read our Editorial: https://t.co/VRJkZ8kVn5#MentalHealth #WMHD2021 pic.twitter.com/hxvrCoMbt0
— The Lancet (@TheLancet) October 10, 2021
Study shows an increased risk of Guillain-Barré Syndrome with the J&J vaccine; the estimated observed to expected rate ratio was 4.18 for the 42-day window.
8 Oct, 2021 | 10:40h | UTC
Commentary on Twitter
Study suggests a potential small but statistically significant safety concern for #GuillainBarré syndrome following receipt of the @JanssenUS #COVID19 vaccine; findings considered preliminary pending analysis of medical records to establish a definitive Dx https://t.co/yZjJVkp6BA
— JAMA (@JAMA_current) October 7, 2021
Choosing Wisely: Seven things physicians and residents/patients should question in long term care.
7 Oct, 2021 | 10:31h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
AAN Position Statement: Ethical perspectives on costly drugs and health care.
5 Oct, 2021 | 08:57h | UTCEthical Perspectives on Costly Drugs and Health Care: AAN Position Statement – Neurology
News release: AAN Issues Ethics Position Statement on Costly Drugs and Health Care – American Academy of Neurology
Neurological Effects of COVID-19 in Children.
1 Oct, 2021 | 10:40h | UTCNeurological Effects of COVID-19 in Children – Pediatric Clinics of North America
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
1 Oct, 2021 | 10:07h | UTCRelated studies:
Cannabinol and Sleep: Separating Fact from Fiction – Cannabis and Cannabinoid Research
Medical Cannabis and Cannabinoids for Impaired Sleep: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – Sleep (link to abstract – $ for full-text)
Review: Clinical features, laboratory, and radiological findings of patients with acute inflammatory myelopathy after COVID-19 infection.
30 Sep, 2021 | 10:27h | UTC
AAN Position Statement: Use of social media in health care—opportunities, challenges, and ethical considerations.
30 Sep, 2021 | 10:19h | UTC
RCT: Maintenance vs. discontinuation of antidepressants in patients who felt well enough to discontinue antidepressant therapy.
30 Sep, 2021 | 10:22h | UTCMaintenance or Discontinuation of Antidepressants in Primary Care – New England Journal of Medicine
Commentaries:
Many can stop anti-depressants without relapse – BBC
Study highlights difficulty of stopping antidepressants – Associated Press
RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.
28 Sep, 2021 | 09:06h | UTCEffect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)
Commentary on Twitter
Small to medium effects of methylphenidate for apathy in AD. Good to see a positive symptomatic treatment trial but I wonder just how important the improvements are to patients and their families. https://t.co/nGSxlAntAd
— Robert Howard (@ProfRobHoward) September 27, 2021
The AUA/SUFU Guideline on Adult Neurogenic Lower Urinary Tract Dysfunction.
26 Sep, 2021 | 21:58h | UTCThe AUA/SUFU Guideline on Adult Neurogenic Lower Urinary Tract Dysfunction – The Journal of Urology
Part I: Diagnosis and Evaluation – The Journal of Urology
Part II: Treatment and Follow up – The Journal of Urology
Phenotypes and subphenotypes of delirium: a review of current categorizations and suggestions for progression.
23 Sep, 2021 | 09:54h | UTC