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Urology

Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer: ASCO guideline update

21 Feb, 2021 | 21:47h | UTC

Initial Management of Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer: ASCO Guideline Update – Journal of Clinical Oncology

 


Preliminary study suggests there may be a role for prostate cancer screening with magnetic resonance imaging

16 Feb, 2021 | 01:50h | UTC

Population-Based Prostate Cancer Screening With Magnetic Resonance Imaging or Ultrasonography: The IP1-PROSTAGRAM Study – JAMA Oncology

Commentaries: Short MRI Protocol Could Be Alternative for Prostate Cancer Follow-Up – Diagnostic Imaging AND Short MRI exam shows promise for prostate cancer screening follow-up – AuntMinnie (free registration required)

 

Commentary on Twitter

 


RCT: Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma

15 Feb, 2021 | 00:36h | UTC

Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Immunotherapy – targeted drug combination improves survival in advanced kidney cancer – Dana-Farber Cancer Institute

 

Commentary on Twitter

 


RCT: Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma

15 Feb, 2021 | 00:34h | UTC

Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: 2021 Genitourinary Cancers Symposium: Enfortumab Vedotin-ejfv Prolongs Survival in Patients With Metastatic Urothelial Carcinoma – The ASCO Post

 


RCT: A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma

15 Feb, 2021 | 00:32h | UTC

A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Cabozantinib most effective treatment for metastatic papillary kidney cancer – MedicalXpress

 


Long-term data: No difference in cardiovascular mortality or morbidity with transdermal estradiol vs. LHRH agonists for androgen suppression in prostate cancer

15 Feb, 2021 | 00:31h | UTC

Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme – The Lancet (link to abstract – $ for full-text)

 


RCT: Radiopharmaceutical therapy vs. cabazitaxel in patients with metastatic castration-resistant prostate cancer

15 Feb, 2021 | 00:29h | UTC

[177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Radionuclide Tx Wins in Third-Line Metastatic CRPC – MedPage Today

 


RCT: Among patients undergoing transurethral resection of the prostate, it is safe to withhold antimicrobial prophylaxis for those without pre-operative pyuria or a pre-operative, indwelling catheter

11 Feb, 2021 | 01:52h | UTC

Antimicrobial Prophylaxis (AMP) in Transurethral Resection of the Prostate (TURP): Results of a Randomized Trial – The Journal of Urology

 


RCT: MRI-targeted biopsy safely reduces the need for biopsy in more than one-third of men at risk for prostate cancer

5 Feb, 2021 | 01:27h | UTC

Comparison of Multiparametric Magnetic Resonance Imaging–Targeted Biopsy With Systematic Transrectal Ultrasonography Biopsy for Biopsy-Naive Men at Risk for Prostate Cancer: A Phase 3 Randomized Clinical Trial – JAMA Oncology

Commentary: Clinical trial: Using MRI for prostate cancer diagnosis equals or beats current standard – Ontario Institute for Cancer Research AND Another Win for MRI and Targeted Prostate Biopsy – MedPage Today (free registration required)

Related: MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis – New England Journal of Medicine (study and commentaries) Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era: A Systematic Review and Meta-analysis – European Urology AND Meta-Analysis: MRI plus Targeted Biopsy vs. Systematic Biopsy Alone for the Diagnosis of Prostate Cancer (studies and commentaries)

 


Small study shows feasibility of MRI-guided focused ultrasound ablation for localized intermediate-risk prostate cancer

3 Feb, 2021 | 01:09h | UTC

MRI-guided Focused Ultrasound Ablation for Localized Intermediate-Risk Prostate Cancer: Early Results of a Phase II Trial – Radiology

Commentary: Study: MRI-guided ultrasound treats prostate cancer with few side effects – UPI

 


ASCO Guideline Update: Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer

28 Jan, 2021 | 01:17h | UTC

Initial Management of Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer: ASCO Guideline Update – Journal of Clinical Oncology

 


Randomized trial: Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer

28 Jan, 2021 | 01:09h | UTC

Prostate-Only Versus Whole-Pelvic Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer (POP-RT): Outcomes From Phase III Randomized Controlled Trial – Journal of Clinical Oncology

 

Commentary on Twitter

 


[Abstract Only] Meta-analysis: Ablation of aldosterone producing adenoma is associated with a reduced operative duration, decreased intraoperative blood loss, and faster postoperative recovery compared to laparoscopic adrenalectomy

21 Jan, 2021 | 00:50h | UTC

Ablation versus laparoscopic adrenalectomy for the treatment of aldosterone‑producing adenoma: a meta-analysis – Abdominal Radiology (link to abstract – $ for full-text)

 


AUA/ASRM Guideline: Diagnosis and treatment of infertility in men

19 Jan, 2021 | 01:21h | UTC

Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline Part I – The Journal of Urology

Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline PART II – The Journal of Urology

 


Randomized trial: Ultra-hypofractionated vs. conventionally fractionated radiotherapy for prostate cancer

19 Jan, 2021 | 01:14h | UTC

Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer (HYPO-RT-PC): patient-reported quality-of-life outcomes of a randomised, controlled, non-inferiority, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Postdischarge virtual visits for low-risk surgeries: A randomized noninferiority clinical trial

17 Jan, 2021 | 21:57h | UTC

Postdischarge Virtual Visits for Low-risk Surgeries: A Randomized Noninferiority Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Surgical Centers Warm Up to Video Chats, Texts for Patient Follow-Up – MedPage Today (free registration required)

 


Systematic review: Prostatic arterial embolization for men with symptomatic benign prostatic hyperplasia provides similar short term (up to 12 months) improvement in urologic symptom scores and quality of life, but with an increase in re-treatment rates

15 Jan, 2021 | 08:11h | UTC

Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia – Cochrane Library

Summary: Prostatic arterial embolization for treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia – Cochrane Library

 


Systematic review: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer

15 Jan, 2021 | 08:10h | UTC

Abiraterone acetate in combination with androgen deprivation therapy compared to androgen deprivation therapy only for metastatic hormone‐sensitive prostate cancer – Cochrane Library

Summary: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer – Cochrane Library

 


CDC Guidelines for Gonococcal Infection, 2020. CDC recommends a single 500 mg intramuscular dose of ceftriaxone for uncomplicated gonorrhea, with oral doxycycline for 7 days when chlamydial coinfection has not been excluded

18 Dec, 2020 | 09:40h | UTC

Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020 – Centers for Disease Control and Prevention

Commentary: CDC Guidelines Recommend Ceftriaxone Monotherapy for Uncomplicated Gonorrhea – NEJM Journal Watch

 

Commentary on Twitter

 


Randomized trial: In kidney transplantation, oxygenated cold perfusion preservation is safe and reduces post-transplant complications compared to standard cold perfusion preservation in kidney transplantation

16 Dec, 2020 | 10:06h | UTC

Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Oxygenated hypothermic perfusion reduces post-kidney transplant complications – 2 Minute Medicine

 


Review: Perioperative venous thromboembolism prophylaxis

3 Dec, 2020 | 08:28h | UTC

Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings

 


Safe surgery: A cluster randomized trial showed that the implementation of control charts with feedback on indicators to surgical teams was associated with concomitant reductions in major adverse events in patients

9 Nov, 2020 | 01:23h | UTC

Effect of monitoring surgical outcomes using control charts to reduce major adverse events in patients: cluster randomised trial – The BMJ

 


Review: Management of common postoperative complications

4 Nov, 2020 | 09:26h | UTC

Management of Common Postoperative Complications – Mayo Clinic Proceedings

 


Randomized trial: Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women

18 Oct, 2020 | 23:06h | UTC

Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women: multicentre randomised controlled trial – The BMJ

Commentary: For Urinary Incontinence, No Need to Add Biofeedback to Pelvic Floor Exercises – NEJM Journal Watch

 

Commentary on Twitter

 


Advanced Prostate Cancer: AUA/ASTRO/SUO Guidelines

24 Sep, 2020 | 09:15h | UTC

Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I – The Journal of Urology

Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II – The Journal of Urology

 


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