Safe surgery: A cluster randomized trial showed that the implementation of control charts with feedback on indicators to surgical teams was associated with concomitant reductions in major adverse events in patients

9 Nov, 2020 | 01:23h | UTC

Effect of monitoring surgical outcomes using control charts to reduce major adverse events in patients: cluster randomised trial – The BMJ

Review: Management of common postoperative complications

4 Nov, 2020 | 09:26h | UTC

Management of Common Postoperative Complications – Mayo Clinic Proceedings

Randomized trial: Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women

18 Oct, 2020 | 23:06h | UTC

Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women: multicentre randomised controlled trial – The BMJ

Commentary: For Urinary Incontinence, No Need to Add Biofeedback to Pelvic Floor Exercises – NEJM Journal Watch

Commentary on Twitter

This RCT did not find a statistically significant or clinically important difference in severity of urinary incontinence between women randomised to electromyographic biofeedback plus pelvic floor muscle training or to pelvic floor muscle training alonehttps://t.co/z8nxLplT57

— The BMJ (@bmj_latest) October 17, 2020

Advanced Prostate Cancer: AUA/ASTRO/SUO Guidelines

24 Sep, 2020 | 09:15h | UTC

Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I – The Journal of Urology

Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II – The Journal of Urology

Catheter-associated urinary tract infections in adults: diagnosis, treatment, and prevention

23 Sep, 2020 | 14:35h | UTC

Catheter-Associated Urinary Tract Infections in Adults: Diagnosis, Treatment, and Prevention – Journal of Hospital Medicine (free for a limited period)

Systematic review: Therapies for clinically localized prostate cancer

20 Sep, 2020 | 21:15h | UTC

Therapies for Clinically Localized Prostate Cancer – Agency for Healthcare Research and Quality

Final report: Therapies for Clinically Localized Prostate Cancer AND Evidence Summary

[Abstract Only] Survival with Olaparib in metastatic castration-resistant prostate cancer

20 Sep, 2020 | 21:13h | UTC

Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer – New England Journal of Medicine

Commentary on Twitter

The PROfound trial showed that olaparib prolonged imaging-based progression-free survival among patients whose tumors contained defects in the BRCA1, BRCA2, or ATM. With longer follow-up, the trial now shows that olaparib prolonged overall survival in these patients. #ESMO20

— NEJM (@NEJM) September 20, 2020

[Abstract Only] Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma

20 Sep, 2020 | 21:11h | UTC

Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma – New England Journal of Medicine

Commentary on Twitter

Maintenance avelumab plus best supportive care significantly prolonged overall survival, as compared with best supportive care alone, among patients with urothelial cancer who had disease that had not progressed with first-line chemotherapy. #ESMO20

— NEJM (@NEJM) September 18, 2020

[Abstract Only] Study: Patient reported outcomes predicting spontaneous stone passage may not have acceptable accuracy

14 Sep, 2020 | 00:55h | UTC

Patient Reported Outcomes Predicting Spontaneous Stone Passage May Not Have Acceptable Accuracy – Journal of Urology (link to abstract – $ for full-text)

Commentary: Predicting Spontaneous Passage of a Ureteral Stone – NEJM Journal Watch (free for a limited period)

[Abstract Only] Randomized trial: Antibiotics vs. no therapy in kidney transplant recipients with asymptomatic bacteriuria

11 Sep, 2020 | 01:10h | UTC

Antibiotics versus no therapy in kidney transplant recipients with asymptomatic bacteriuria (BiRT): a pragmatic, multicentre, randomised controlled trial – Clinical Microbiology and Infection

Commentary on Twitter

More data ❌ screening/Rxing asymptomatic bacteriuria in kidney transplantation

199 KTx recipients (>2 mo out) randomized to Rx/no Rx for ASB

Rx arm had
💊No ⬇️ in symptomatic UTI
💊5x more ABx exposure
💊subsequent bacteriuria w resistant bacteria #TxID https://t.co/a7aVjIJj0z pic.twitter.com/ngTkJLHCfU

— Ilan Schwartz MD PhD (@GermHunterMD) September 10, 2020

[Abstract Only] Randomized trial: Nonmetastatic, castration-resistant prostate cancer and survival with darolutamide

10 Sep, 2020 | 09:33h | UTC

Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide – New England Journal of Medicine

[Abstract Only] Randomized trial: Intravenous lidocaine for the prevention of postoperative catheter-related bladder discomfort in male patients undergoing transurethral resection of bladder tumors

14 Aug, 2020 | 01:03h | UTC

Intravenous Lidocaine for the Prevention of Postoperative Catheter-Related Bladder Discomfort in Male Patients Undergoing Transurethral Resection of Bladder Tumors: A Randomized, Double-Blind, Controlled Trial – Anesthesia & Analgesia

Commentary on Twitter

IV #lidocaine administration resulted in lower incidence of moderate-to-severe CRBD, lower #opioid requirement, & higher #PatientSatisfaction in males undergoing TURBT without evidence of significant side effects @cuhpr https://t.co/OPOGkZl2Dd pic.twitter.com/RjcRP8UzlA

— Anesthesia&Analgesia (@IARS_Journals) July 10, 2020