Antibiotic Stewardship | Links Medicus Content Curation & Alerts in Medicine

Looking to improve antibiotic use at discharge? Check out our ROAD Home Framework: Reducing Overuse of Antibiotics at Discharge Home. 🔥🔥🔥 at CID. https://t.co/mTKlaNerpC Excited for my first pub with the amazing @EmilySpivak and Adam Hersh! #stewarship @IDSAInfo pic.twitter.com/BMkD1M6Rqs

— Valerie Vaughn (@ValerieVaughnMD) September 23, 2021

Less common bacterial, fungal and viral infections: review of management in the pregnant patient.

26 Sep, 2021 | 21:38h | UTC

Less common bacterial, fungal and viral infections: review of management in the pregnant patient – Drugs in Context

RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.

24 Sep, 2021 | 09:00h | UTC

Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial – The Lancet

Commentary on Twitter

#Antibiotic resistance is a global public health threat.

New trial indicates, unless pneumonia is suspected, clinicians should provide safety-netting advice but not prescribe antibiotics for most children presenting with chest infections. https://t.co/mOwLG5rZd1 #AMR pic.twitter.com/b0c7Z5flQk

— The Lancet (@TheLancet) September 23, 2021

WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18 – In many countries, ciprofloxacin resistance was exceedingly high, and decreased susceptibility or resistance to ceftriaxone and cefixime continued to emerge.

24 Sep, 2021 | 08:53h | UTC

WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18: a retrospective observational study – The Lancet Microbe

RCT: Probiotics do not reduce the incidence of ventilator-associated pneumonia in critically ill patients.

22 Sep, 2021 | 10:03h | UTC

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: Probiotic Flops for Ventilator-Associated Pneumonia Prevention – MedPage Today (free registration required)

Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.

22 Sep, 2021 | 10:02h | UTC

Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial – The BMJ

Cluster RCT: Procalcitonin point-of-care testing may reduce antibiotic prescription for patients with suspected lower respiratory tract infection in primary care.

22 Sep, 2021 | 10:01h | UTC

Procalcitonin and lung ultrasonography point-of-care testing to determine antibiotic prescription in patients with lower respiratory tract infection in primary care: pragmatic cluster randomised trial – The BMJ

Large cohort study suggests routine replacement (every 96 hours) of peripheral intravenous catheters may reduce the risk of bloodstream infections compared to clinically indicated replacement.

19 Sep, 2021 | 23:34h | UTC

Comparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters – JAMA Internal Medicine (free for a limited period)

Related Cochrane Review with different findings: Systematic Review: Clinically‐indicated vs. Routine Replacement of Peripheral Venous Catheters

Commentary on Twitter

Phlebitis due to peripheral venous catheters is not a proxy for bloodstream infection. A large prospective study shows that clinically indicated replacement of peripheral venous catheters may put patients at risk of bloodstream infection https://t.co/SNo4SpfoKE

— JAMA Internal Medicine (@JAMAInternalMed) September 17, 2021

As Covid Cases Rise, So Do Hospital-Related Infections.

17 Sep, 2021 | 10:08h | UTC

As Covid Cases Rise, So Do Hospital-Related Infections – Wired

A guide to the treatment of cellulitis and other soft-tissue infections.

16 Sep, 2021 | 09:47h | UTC

A guide to the Tx of cellulitis and other soft-tissue infections – Journal of Family Practice

Antifungal Susceptibility Testing: A Primer for Clinicians.

14 Sep, 2021 | 08:46h | UTC

Antifungal Susceptibility Testing: A Primer for Clinicians – Open Forum Infectious Diseases

Commentary on Twitter

New in OFID: An overview for clinicians on antifungal susceptibility testing, including testing methods and their limitations, and how results may or may not be clinically useful.

📄:https://t.co/ZhPL5oQ57F #OpenForumInfectDis #IDSAJournals @PaulSaxMD @DrJLi pic.twitter.com/wrIkBc5MPV

— IDSA (@IDSAInfo) September 11, 2021

RCT: A Seven-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales was noninferior to a 14-days course.

9 Sep, 2021 | 09:03h | UTC

Seven versus 14-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales. A randomized, controlled trial – Clinical Microbiology and Infection

Commentary on Twitter

SHORTEN RCT 🔥🔥🔥@CMIJournal
Seven versus 14-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales
7-day course of antibiotics as the preferential treatment for eBSI, as long as the source is properly controlled https://t.co/pyaOMl52us pic.twitter.com/wK1sgeMe36

— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 8, 2021