Antibiotic Stewardship
Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults
27 Jan, 2023 | 11:55h | UTC
RCT | 2 days of postoperative antibiotics is noninferior to 5 days in patients with complex appendicitis
24 Jan, 2023 | 14:33h | UTC2 days versus 5 days of postoperative antibiotics for complex appendicitis: a pragmatic, open-label, multicentre, non-inferiority randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary: Trial supports shorter postoperative antibiotics for complex appendicitis – CIDRAP
Commentary on Twitter
After laparoscopic appendicectomy for complex appendicitis, 2 days versus 5 days of intravenous #antibiotics was non-inferior in terms of infectious complications and mortality within 90 days, suggests new Dutch study: https://t.co/oRsf8BQgAd
— The Lancet (@TheLancet) January 19, 2023
ASCO Guideline | Management of fever and neutropenia in pediatric patients with cancer and hematopoietic cell transplantation recipients
24 Jan, 2023 | 14:28h | UTC
Recommendations for the diagnosis and management of COVID-19 associated bacterial and fungal infections
20 Jan, 2023 | 14:48h | UTC
RCT | Aqueous povidone-iodine vs. normal saline for intraoperative wound irrigation on the incidence of SSI after GI surgery
19 Jan, 2023 | 13:54h | UTCAqueous Povidone-Iodine Versus Normal Saline For Intraoperative Wound Irrigation On The Incidence Of Surgical Site Infection In Clean-Contaminated Wounds After Gastroenterological Surgery: A Single Institute, Prospective, Blinded-Endpoint, Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)
Review | Surgical site infection prevention
18 Jan, 2023 | 14:31h | UTCSurgical Site Infection Prevention: A Review – JAMA (free for a limited period)
Author interview: Surgical Site Infection Prevention – JAMA
Related:
Global guidelines on the prevention of surgical site infection – World Health Organization
AAOS Guideline: Prevention of surgical site infections after major extremity trauma.
Consensus statement | Use of a 4-month treatment regimen for drug susceptible TB in children with uncomplicated disease
18 Jan, 2023 | 14:25h | UTC
SR | Pre‐emptive antifungal therapy vs. empirical antifungal therapy for febrile neutropenia in people with cancer
18 Jan, 2023 | 14:18h | UTC
SHEA statement on antibiotic stewardship in hospitals during public health emergencies
17 Jan, 2023 | 13:18h | UTC
Review | Viral infections in critical care
17 Jan, 2023 | 13:01h | UTCViral infections in critical care: a narrative review – Anaesthesia
M-A | Colonisation with ESCR-Enterobacterales and infection risk in surgical patients
17 Jan, 2023 | 12:58h | UTC
Best infectious diseases articles from 2022 – A year end review of non-COVID literature
15 Jan, 2023 | 20:31h | UTC
Commentary on Twitter
🔥🔥NEW 🔥🔥
Our new post, a great collaboration w 🌟 @IDstewardship
Best Infectious Diseases Articles From 2022 – A Year End Review Of Non-COVID Literature
1️⃣7️⃣⚡️🆔 RCTs @NEJM @TheLancet ✨
2️⃣syst Rev
3️⃣🌏Guidelines @Wiki_Guidelines
#IDTwitter #TwitteRxhttps://t.co/JL07NLa3BV pic.twitter.com/Qcf2cwK8Sd— Antibiotic Steward Bassam Ghanem🆔🌟 (@ABsteward) January 4, 2023
RCT | Colistin monotherapy vs. combination therapy for carbapenem-resistant organisms
13 Jan, 2023 | 13:36h | UTCColistin Monotherapy versus Combination Therapy for Carbapenem-Resistant Organisms – NEJM Evidence
Commentary: Colistin Alone or with Meropenem: Is More Better? – NEJM Journal Watch
Study suggests delivering high concentrations of antibiotics into the implantation site is feasible for infections in implanted CV electronic devices
13 Jan, 2023 | 13:26h | UTCRegional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Direct Delivery of Antibiotics to CV Device Pocket Infections Appears Promising – TCTMD
Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease
13 Jan, 2023 | 13:25h | UTCNews Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom
Commentaries:
Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP
Antibiotic Exposure Positively Linked to IBD Development – HealthDay
Commentary on Twitter
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al
"Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" viahttps://t.co/zc9bG3CpSm#GUTInTheNews pic.twitter.com/xra8wfEgnr
— Gut Journal (@Gut_BMJ) January 9, 2023
RCT | Second-line levofloxacin-based quadruple therapy vs. bismuth-based quadruple therapy for Helicobacter pylori eradication
12 Jan, 2023 | 13:06h | UTCSecond-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Liou et al – Second-line levofloxacin-based quadruple therapy vs bismuth-based quadruple therapy for H pylori eradication and long-term changes to the gut #microbiota and antibiotic resistome: an RCThttps://t.co/Aipu3TRyFr#Hpylori #microbiome #AMR @emadelomar pic.twitter.com/aeFMAI3FCj
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 20, 2022
SR | Interventions for the eradication of methicillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis
12 Jan, 2023 | 13:04h | UTC
Review | Early diagnosis and prevention of infections in cirrhosis
12 Jan, 2023 | 12:47h | UTCEarly Diagnosis and Prevention of Infections in Cirrhosis – Seminars in Liver Disease
RCT | Efficacy and safety of azithromycin vs. placebo to treat lower respiratory tract infections associated with low procalcitonin.
16 Dec, 2022 | 13:30h | UTCEfficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter
New research: Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trialhttps://t.co/EZW7YdxPPU pic.twitter.com/4zlsVN5NtT
— The Lancet Infectious Diseases (@TheLancetInfDis) December 14, 2022
SR | Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
14 Dec, 2022 | 14:51h | UTCTreatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins – Cochrane Library
Prevention of device-related infections in patients with cancer: Current practice and future horizons.
13 Dec, 2022 | 14:30h | UTC
WHO Report signals increasing resistance to antibiotics in bacterial infections in humans.
12 Dec, 2022 | 12:52h | UTCCommentary: WHO report shows rising antibiotic resistance, need for better data – CIDRAP
Commentary on Twitter (thread – click for more)
New WHO report on #AntimicrobialResistance reveals very high levels of resistance in common bacteria frequently causing bloodstream infections in hospitals.
Infection prevention & control is critical to stop the spread and save lives.
More: https://t.co/8dGqw5KgZT pic.twitter.com/XGC2I7KbwB
— World Health Organization (WHO) (@WHO) December 9, 2022
Approach to fever in patients with neutropenia: a review of diagnosis and management.
8 Dec, 2022 | 12:44h | UTCRelated:
Podcast | Procalcitonin revisited.
7 Dec, 2022 | 14:17h | UTCAnnals On Call – Procalcitonin Revisited – Annals of Internal Medicine
RCT | Efficacy of postoperative oral cephalexin and metronidazole on SSI in obese women undergoing cesarean section.
7 Dec, 2022 | 14:13h | UTC