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Oncology – Breast

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomized trials.

15 Oct, 2021 | 02:07h | UTC

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials – The Lancet Oncology

 

Commentary on Twitter

 


Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

1 Oct, 2021 | 10:21h | UTC

Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study – JACC: CardioOncology

Commentaries:

Left Breast Radiation Therapy Doubles CV Disease Risk vs. Right Breast Radiation Therapy in Young Women – American College of Cardiology

CAD in Young Women After Radiation Therapy for Breast Cancer – American College of Cardiology

 

Commentary on Twitter

 


Systematic Review: Partial breast irradiation versus whole breast radiotherapy for early breast cancer.

15 Sep, 2021 | 08:46h | UTC

Partial breast irradiation versus whole breast radiotherapy for early breast cancer – Cochrane Library

 

Commentary on Twitter

 


Long-term report of study evaluating radiation following surgical excision for good-risk ductal carcinoma in situ.

14 Sep, 2021 | 08:44h | UTC

Randomized Phase III Trial Evaluating Radiation Following Surgical Excision for Good-Risk Ductal Carcinoma In Situ: Long-Term Report From NRG Oncology/RTOG 9804 – Journal of Clinical Oncology

 

Commentary on Twitter

 


Review: neoadjuvant endocrine therapy in clinical practice.

12 Sep, 2021 | 21:34h | UTC

Neoadjuvant Endocrine Therapy in Clinical Practice: A Review – JAMA Oncology (free for a limited period)

 


Systematic review finds there is insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny.

10 Sep, 2021 | 05:12h | UTC

Insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny – The BMJ

Original study: Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy – The BMJ

 

Commentary on Twitter

 


Cohort study: Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers.

20 Aug, 2021 | 08:39h | UTC

Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study – American Journal of Obstetrics and Gynecology

 

Commentary on Twitter

 


Oncoplastic breast surgery: A guide to good practice.

19 Aug, 2021 | 08:40h | UTC

Oncoplastic breast surgery: A guide to good practice – European Journal of Surgical Oncology

 


ASCO Guideline Update: Chemotherapy and Targeted Therapy for Patients with Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer That is Either Endocrine-Pretreated or Hormone Receptor–Negative.

12 Aug, 2021 | 08:52h | UTC

Chemotherapy and Targeted Therapy for Patients With Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer That is Either Endocrine-Pretreated or Hormone Receptor–Negative: ASCO Guideline Update – Journal of Clinical Oncology

 


ASCO Guideline Update: Endocrine Treatment and Targeted Therapy for Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer.

30 Jul, 2021 | 11:51h | UTC

Endocrine Treatment and Targeted Therapy for Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer: ASCO Guideline Update – Journal of Clinical Oncology

 


Management of the Axilla in Early-Stage Breast Cancer: Ontario Health (Cancer Care Ontario) and ASCO Guideline.

30 Jul, 2021 | 11:49h | UTC

Management of the Axilla in Early-Stage Breast Cancer: Ontario Health (Cancer Care Ontario) and ASCO Guideline – Journal of Clinical Oncology

 


RCT: Duration of adjuvant aromatase-inhibitor therapy in postmenopausal breast cancer.

30 Jul, 2021 | 11:43h | UTC

Duration of Adjuvant Aromatase-Inhibitor Therapy in Postmenopausal Breast Cancer – New England Journal of Medicine

 

Commentary on Twitter

 


Systematic review: Breast Reconstruction After Mastectomy.

22 Jul, 2021 | 10:45h | UTC

Breast Reconstruction After Mastectomy – Agency for Healthcare Research and Quality

 


Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.

14 Jul, 2021 | 11:07h | UTC

Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study – The Lancet Oncology

News release: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet

Commentaries: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian AND Expert reaction to study of alcohol and cancer – Science Media Centre

 


M-A: Pregnancy After Breast Cancer – “These results provide reassuring evidence on the safety of conceiving in BC survivors”.

6 Jul, 2021 | 09:55h | UTC

Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis – Journal of Clinical Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


RCT: Similar outcomes with 5 vs. 2 years of zoledronate treatment following adjuvant chemotherapy in early breast cancer.

1 Jul, 2021 | 09:50h | UTC

Outcomes With 5 vs 2 Years of Zoledronate Treatment Following Adjuvant Chemotherapy in Early Breast Cancer – The ASCO Post

Original Study: Prognosis of Patients With Early Breast Cancer Receiving 5 Years vs 2 Years of Adjuvant Bisphosphonate Treatment: A Phase 3 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)

 


RCT: Heart-protecting drugs likely unnecessary for most breast cancer patients undergoing adjuvant treatment.

8 Jun, 2021 | 09:15h | UTC

Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA) Extended Follow-Up of a 2×2 Factorial, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Candesartan and Metoprolol – Circulation

Commentaries: Heart-protecting drugs likely unnecessary for many breast cancer patients – American College of Cardiology

 


Population-based cohort study suggests increased survival after breast conservation surgery + radiotherapy compared to mastectomy with or without radiotherapy in women with breast cancer.

10 May, 2021 | 00:42h | UTC

Survival After Breast Conservation vs Mastectomy Adjusted for Comorbidity and Socioeconomic Status: A Swedish National 6-Year Follow-up of 48 986 Women – JAMA Surgery

Commentary: Breast-Conserving Surgery+RT Yields Significant Survival Benefits For Early-Stage Breast Cancer – Physician’s Weekly

 

Commentary on Twitter

 


AHA Scientific Statement: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormonal therapies

29 Apr, 2021 | 08:33h | UTC

Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications: A Scientific Statement From the American Heart Association – Circulation: Genomic and Precision Medicine

News release: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormones – American Heart Association

Top Things to Know: Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System – American Heart Association

Commentaries: Hormonal Therapy for Breast and Prostate Cancer: Lessons and Opportunities – American Heart Association AND Hormonal Based Therapies in the Treatment of Breast and Prostate Cancer – balancing the risks! – American Heart Association AND Hormone Cancer Therapies Increase CV Risk: AHA Scientific Statement – TCTMD AND Closely Monitor Heart Health in Cancer Patients Who Get Hormonal Therapies: AHA – HealthDay

 


Systematic Review: PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer

23 Apr, 2021 | 08:16h | UTC

PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer – Cochrane Library

Summary: PARP inhibitors for locally advanced or metastatic breast cancer – Cochrane Library

 


RCT: Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer

22 Apr, 2021 | 08:15h | UTC

Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 


70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age

14 Mar, 2021 | 20:07h | UTC

70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age – The Lancet Oncology (link to abstract – $ for full-text)

 


Guide to enhanced recovery for cancer patients undergoing breast surgery and reconstruction

14 Mar, 2021 | 20:01h | UTC

Guide to Enhanced Recovery for Cancer Patients Undergoing Breast Surgery and Reconstruction – Annals of Surgical Oncology

Related: Consensus Review of Optimal Perioperative Care in Breast Reconstruction: Enhanced Recovery after Surgery (ERAS) Society Recommendations – Plastic and Reconstructive Surgery

 


Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

5 Mar, 2021 | 08:35h | UTC

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance – The BMJ

Recommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit

Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

 


2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients

28 Feb, 2021 | 21:42h | UTC

Case series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology

Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology

Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology

Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital

Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)

 


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