Gynecology & Obstetrics (all articles)
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
15 Oct, 2021 | 02:41h | UTCCovid-19 treatments and vaccines must be evaluated in pregnancy – The BMJ
Related:
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
Inconsistent messaging from authorities, driven by lack of trial data, has increased covid-19 vaccine hesitancy among pregnant women@DrAllyah and colleagues argue that pregnant women should be included in drug and vaccine development from the outsethttps://t.co/P3v1ouk8tQ
— The BMJ (@bmj_latest) October 14, 2021
Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.
15 Oct, 2021 | 02:38h | UTCRelated:
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter (thread – click for more)
First dataset I have seen for vaccine efficacy in pregnant persons during #Delta era. Impressive aOR for both severe illness (0.11) and infection positivity in general (0.31)! #GetVaccinatedNow 🤰🏻💉 https://t.co/VhBHyeOWjz
— Lauren Hassen, MD MPH (@ljhassen) October 14, 2021
RCT: Laser treatment not better than sham treatment on symptom severity in women with postmenopausal vaginal symptoms.
13 Oct, 2021 | 01:30h | UTCEffect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Time for a “Pause” on the Use of Vaginal Laser (free for a limited period)
Author Interview: Effect of Carbon Dioxide Laser vs Sham Therapy on Women With Postmenopausal Vaginal Symptoms
Commentary: Vagina lasering for postmenopausal women ‘may be placebo’ – The Guardian
Commentary on Twitter
In a randomized clinical trial among women with postmenopausal vaginal symptoms, treatment with fractional carbon dioxide laser vs sham treatment did not improve vaginal symptoms after 12 months https://t.co/XXv5edTLiL
— JAMA (@JAMA_current) October 12, 2021
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018.
13 Oct, 2021 | 01:21h | UTCInvited commentary: Anemia in women — an intractable problem that requires innovative solutions – Nature Medicine
Review | Chronic hypertension and superimposed preeclampsia: screening and diagnosis.
3 Oct, 2021 | 22:23h | UTC
USPSTF Statement: Start low-dose aspirin after 12 weeks of gestation for women at high risk for preeclampsia.
29 Sep, 2021 | 10:12h | UTCEditorial: Low-Dose Aspirin for the Prevention of Preeclampsia
Commentary: Aspirin Use to Prevent Preeclampsia: USPSTF Recommendation – American College of Cardiology
Author interview: USPSTF Recommendation: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality – JAMA
JAMA Patient Page: Use of Aspirin During Pregnancy to Prevent Preeclampsia
Preliminary randomized trial suggests metformin may prolong gestation in preterm pre-eclampsia.
29 Sep, 2021 | 10:02h | UTCNews release: Diabetes drug may help to prolong preterm pregnancies in women with pre-eclampsia – British Medical Journal
Commentary: Metformin May Prolong Gestation in Women With Preterm Preeclampsia – HealthDay
Commentary on Twitter
This trial suggests that extended release metformin can prolong gestation in women with preterm pre-eclampsia, providing proof of concept that treatment of preterm pre-eclampsia is possible, say the authorshttps://t.co/gqVef7ss4s @cathycluver
— The BMJ (@bmj_latest) September 25, 2021
Consensus Statement: Paracetamol use during pregnancy — a call for precautionary action – “Pregnant women should minimize risk by using the lowest effective APAP dose for the shortest possible time”.
26 Sep, 2021 | 22:02h | UTCParacetamol use during pregnancy — a call for precautionary action – Nature Reviews Endocrinology
Editorial: Caution needed: paracetamol use in pregnancy – Nature Reviews Endocrinology
Commentaries:
New research cautions about possible risks of acetaminophen use during pregnancy – STAT
Expert reaction to statement on paracetamol use during pregnancy – Science Media Centre
A Common Pain Relief Med Used in Pregnancy Should Be Taken with Caution, Experts Warn – ScienceAlert
Commentary on Twitter
New content online: Paracetamol use during pregnancy — a call for precautionary action https://t.co/FhsB5KdRs0 pic.twitter.com/8BQUUWeTbN
— Nature Reviews Endocrinology (@NatureRevEndo) September 23, 2021
Less common bacterial, fungal and viral infections: review of management in the pregnant patient.
26 Sep, 2021 | 21:38h | UTC
Systematic review: Instruments for assisted vaginal birth.
26 Sep, 2021 | 21:35h | UTCInstruments for assisted vaginal birth – Cochrane Library
Summary: Instruments for assisted vaginal birth – Cochrane Library
Large, multinational cohort suggests ondansetron use in pregnancy does not increase the risk for adverse fetal outcomes.
24 Sep, 2021 | 08:57h | UTCEditorial: Providing Data to Empower Pregnant Patients to Make Evidence-Based Choices
Commentary on Twitter
This cohort study found there was no association between ondansetron exposure during pregnancy and increased risk of fetal death, spontaneous abortion, stillbirth, or major congenital malformations compared with exposure to other antiemetic drugs. https://t.co/hDXr72Ga01
— JAMA Network Open (@JAMANetworkOpen) April 23, 2021
WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18 – In many countries, ciprofloxacin resistance was exceedingly high, and decreased susceptibility or resistance to ceftriaxone and cefixime continued to emerge.
24 Sep, 2021 | 08:53h | UTC
An Update on Coronavirus Disease 2019 (COVID-19) and Pregnancy.
21 Sep, 2021 | 09:51h | UTC
Case series: Assessment of silicone particle migration among women undergoing removal or revision of silicone breast implants in the Netherlands.
21 Sep, 2021 | 08:59h | UTCInvited commentary: Silicone Breast Implants and Disease—Many Questions Unanswered
Commentary on Twitter
In this case series including women w noncohesive or cohesive silicone gel breast implants, silicone leakage occurred in 98.8% of women, indicating silicone gel bleed, and in 86.6% of women, migration of silicone particles outside the capsule was detected. https://t.co/tyCpLw565Z
— JAMA Network Open (@JAMANetworkOpen) September 20, 2021
RCT: Tamsulosin may prevent postoperative urinary retention following female pelvic reconstructive surgery.
17 Sep, 2021 | 09:56h | UTCTamsulosin vs placebo to prevent postoperative urinary retention following female pelvic reconstructive surgery: a multicenter randomized controlled trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Continuous Medical Education in Obstetric Medicine – Short reviews on key topics: 1) Tachycardia in Pregnancy; 2) Metabolic Emergencies; 3) Liver Diseases; 4) Covid-19; 5) Severe Hypertension.
17 Sep, 2021 | 09:55h | UTCHomepage – Clinical Medicine Journal
Tachycardia in pregnancy: when to worry?
Metabolic emergencies in pregnancy
Severe hypertension in pregnancy
The USPSTF maintains the recommendation to screen for chlamydia and gonorrhea in all sexually active women 24 years or younger and in women 25 years or older who are at increased risk for infection.
15 Sep, 2021 | 08:57h | UTCEditorial: Screening for Chlamydia and Gonorrhea – JAMA
Evidence Report : Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Author Interview: USPSTF Recommendation: Screening for Chlamydia and Gonorrhea
JAMA Patient Page: Screening for Chlamydia and Gonorrhea
Supplement: FIGO Working Group for Preterm Birth – Good Practice Recommendations.
15 Sep, 2021 | 08:56h | UTCEditorial: FIGO good practice recommendations for reducing preterm birth and improving child outcomes
FIGO good practice recommendations on modifiable causes of iatrogenic preterm birth
FIGO good practice recommendations on progestogens for prevention of preterm delivery
FIGO good practice recommendations on cervical cerclage for prevention of preterm birth
FIGO good practice recommendations on delayed umbilical cord clamping
Review | Recommendations and Nutritional Considerations for Female Athletes: Health and Performance.
15 Sep, 2021 | 08:49h | UTC
Systematic Review: Partial breast irradiation versus whole breast radiotherapy for early breast cancer.
15 Sep, 2021 | 08:46h | UTC
Commentary on Twitter
For women with early-stage #BreastCancer, how does giving radiotherapy to part of the breast compare with giving #radiotherapy to the whole breast? The latest Cochrane Review from @CochraneBCancer brings together nine studies, which involved 15,187 women: https://t.co/fVuSrSDAZM pic.twitter.com/QOufZYSH5I
— Cochrane UK (@CochraneUK) September 3, 2021
Management of high-risk pulmonary embolism in pregnancy.
15 Sep, 2021 | 08:43h | UTCManagement of high-risk pulmonary embolism in pregnancy – Thrombosis Research
Long-term report of study evaluating radiation following surgical excision for good-risk ductal carcinoma in situ.
14 Sep, 2021 | 08:44h | UTC
Commentary on Twitter
At 15 years, NRG-RTOG 9804 "good risk" breast #DCIS trial shows advantage of radiation therapy over observation to reduce #breastcancer risk https://t.co/l5OWVOb5Dg
#JCO #BCSM #radonc @NRGOnc; @MSK_RadOnc pic.twitter.com/TPAZRheoHT— ASCO Publications (@ASCO_pubs) September 10, 2021
Systematic review finds there is insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny.
10 Sep, 2021 | 05:12h | UTCOriginal study: Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy – The BMJ
Commentary on Twitter
A systematic review of #AI for mammography is very disappointing
"Thirty four (94%) of 36 AI systems evaluated in these studies were less accurate than a single radiologist, and all were less accurate than consensus of two or more radiologists"https://t.co/zqFTxojU9J @bmj_latest pic.twitter.com/wylwOsf4ua— Eric Topol (@EricTopol) September 2, 2021
Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.
9 Sep, 2021 | 10:04h | UTCStudy 1: Spontaneous Abortion Following COVID-19 Vaccination During Pregnancy – JAMA
Study 2: Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion – New England Journal of Medicine
Commentary on Twitter
📣 NO LINK BETWEEN MISCARRIAGE & COVID VACCINATION
This @JAMA_current study examined 105446 pregnancies, including 13160 miscarriages
Women with pregnancies ending in miscarriage were NOT more likely to have had 💉 in prior 28 days than those that didnthttps://t.co/7cFELq1oPM
— Ilan Schwartz MD PhD (@GermHunterMD) September 8, 2021
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
7 Sep, 2021 | 21:48h | UTCEffectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy – Nature Medicine
Commentaries on Twitter
NEW: Estimated vaccine effectiveness in #pregnancy from 7 through to 56 d after second dose was 96% (95% CI; 89–100%) for any documented infection, 97% (91–100%) for infections with documented symptoms & 89% (43–100%) for #COVID19-related hospitalization. https://t.co/bm950wUWGL
— All Source Pregnancy (@PregnancyAll) September 7, 2021
The Pfizer-BioNTech mRNA COVID-19 vaccine was estimated to have high vaccine effectiveness in pregnant women, which is similar to the effectiveness estimated in the general population, according to a @NatureMedicine paper. https://t.co/oz5zn7zNdq pic.twitter.com/9IP5ocxzXs
— Nature Portfolio (@NaturePortfolio) September 7, 2021