Gynecology & Obstetrics (all articles)
RCTs: Once daily oral relugolix combination therapy vs. placebo in patients with endometriosis-associated pain.
23 Jun, 2022 | 10:30h | UTCCommentaries:
Relugolix combination therapy for endometriosis pain – The Lancet (free registration required)
Commentary on Twitter
Treatment options for #endometriosis-associated pain are suboptimal.
Two new studies indicate once-daily relugolix combination therapy significantly improved pain and was well tolerated. 1/2 https://t.co/LBFgTMZSO2
— The Lancet (@TheLancet) June 21, 2022
International consensus statements on pre-invasive vulvar lesions.
23 Jun, 2022 | 10:21h | UTCNews Release: New Guidelines Address Treatment of Pre-Invasive Lesions of the Vulva – Wolters Kluwer Health: Lippincott
Review: SARS-CoV-2 infection and COVID-19 vaccination in pregnancy.
22 Jun, 2022 | 12:09h | UTCSARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology
Review: Sex differences in sequelae from COVID-19 infection and in long COVID syndrome.
22 Jun, 2022 | 12:06h | UTCCommentary: Women more likely to have long COVID, different symptom profile – CIDRAP
M-A: Overweight/obesity in childhood and the risk of early puberty.
21 Jun, 2022 | 10:36h | UTCRelated Study: Patterns of Early Life Weight Gain and Female Onset of Puberty – Journal of the Endocrine Society
RCT: Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF.
21 Jun, 2022 | 10:32h | UTCRelated: Fresh versus frozen embryo transfers in assisted reproduction – Cochrane Library
Opinion | Normalizing menopause – “Martha Hickey and colleagues argue that social and cultural attitudes contribute to the varied experience of menopause and that medicalization fuels negative perceptions”.
20 Jun, 2022 | 10:38h | UTCNormalizing menopause – The BMJ (free for a limited period)
News Release: Medicalizing menopause may be unhelpful for some women – British Medical Journal
Commentary: Menopause is not a disease. Experts call for new narrative for this natural stage of a woman’s life – CNN
NCCN Updated Guideline: Breast cancer.
20 Jun, 2022 | 01:24h | UTC
The clinician’s guide to prevention and treatment of osteoporosis.
20 Jun, 2022 | 01:22h | UTCThe clinician’s guide to prevention and treatment of osteoporosis – Osteoporosis International
Cohort Study: Association of screening with digital breast tomosynthesis vs. digital mammography with risk of interval invasive and advanced breast cancer.
17 Jun, 2022 | 11:09h | UTCAssociation of Screening With Digital Breast Tomosynthesis vs Digital Mammography With Risk of Interval Invasive and Advanced Breast Cancer – JAMA (free for a limited period)
Editorial: Digital Breast Tomosynthesis and Detection of Interval Invasive and Advanced Breast Cancers – JAMA (free for a limited period)
News Release: 3-D Mammography Technique Benefits Some Women, Not All – University of California San Francisco
M-A: Treatment outcomes among pregnant patients with multidrug-resistant tuberculosis.
15 Jun, 2022 | 10:47h | UTC
Commentary on Twitter
This meta-analysis of pregnant patients treated for multi-drug-resistant tuberculosis (MDR-TB) found 73% treatment success and 73% favorable pregnancy outcomes, with adverse events (incl liver/kidney impairment, hearing loss) in more than half of patients. https://t.co/Mx5RLiwhU9
— JAMA Network Open (@JAMANetworkOpen) June 10, 2022
Regional lymphadenopathy following COVID-19 vaccination in patients with or suspicious of breast cancer: a quick summary of current key facts and recommendations.
14 Jun, 2022 | 11:07h | UTCRelated:
2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
ESMO Guideline: Diagnosis, treatment, and follow-up of endometrial cancer.
13 Jun, 2022 | 08:08h | UTC
Expert Analysis: Pericarditis management in pregnancy.
13 Jun, 2022 | 07:49h | UTCPericarditis Management in Pregnancy – American College of Cardiology
Circulating tumor DNA and late recurrence in high-risk hormone receptor–positive, human epidermal growth factor receptor 2–negative breast cancer.
13 Jun, 2022 | 07:35h | UTCCommentary: Tumor DNA Assay Portends Metastatic Breast Cancer Recurrence Months in Advance — First evidence for patients in late adjuvant setting, years after initial diagnosis – MedPage Today (free registration required)
Commentary on Twitter
103 women in long-term remission from high-risk HR+/HER2- breast cancer had customized monitoring of recurrence based on ctDNA seq for tumour-associated mut. Among 8 pts MRD+ pts, 6 developed distant recurrence at a median 12.4 mo after ctDNA positivity https://t.co/aX1ruLCSbb
— NatureRevClinOncol (@NatRevClinOncol) June 9, 2022
Cohort Study: Neurodevelopmental outcomes at 1 year in infants of mothers who tested positive for SARS-CoV-2 during pregnancy.
10 Jun, 2022 | 12:14h | UTCCommentaries:
Commentary on Twitter
This cohort study of #SARSCoV2 exposure in utero found preliminary evidence that maternal SARS-CoV-2 may be associated with neurodevelopmental sequelae in some offspring. https://t.co/dYdoJbNOdl
— JAMA Network Open (@JAMANetworkOpen) June 9, 2022
Systematic review: educational interventions to improve the menstrual health of young adolescent girls.
10 Jun, 2022 | 10:59h | UTC
[News release – not published yet] Women not being routinely informed that a common anesthetic may lessen contraception effectiveness, doctors warn.
9 Jun, 2022 | 11:31h | UTCCommentary: Women in UK ‘seldom’ told drug used in surgery can impede contraception – The Guardian
Screening every five years safe for women who test negative for HPV, study confirms.
9 Jun, 2022 | 11:26h | UTCNews Release: Screening every five years safe for women who test negative for HPV, study confirms – King’s College London
Editorial: HPV screening for cervical cancer is reaching maturity – The BMJ
Related WHO Guidance:
News release: New recommendations for screening and treatment to prevent cervical cancer – World Health Organization
Related USPSTF Guidance: Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement – JAMA
Migraine history tied to higher risk for adverse pregnancy outcomes.
9 Jun, 2022 | 10:49h | UTCMigraine History Tied to Higher Risk for Adverse Pregnancy Outcomes – HealthDay
Cohort Study: Long-term quality of life in patients with breast cancer after breast conservation vs mastectomy and reconstruction.
9 Jun, 2022 | 10:30h | UTCLong-term Quality of Life in Patients With Breast Cancer After Breast Conservation vs Mastectomy and Reconstruction – JAMA Surgery (link to abstract – $ for full-text)
Commentaries:
Long-Term QOL Examined for Surgical Choices in Breast Cancer – HealthDay
Commentary on Twitter
Survey of #breastcancer survivors after treatment found:
1. Breast satisfaction and physical well-being similar with lumpectomy+rads or mastectomy+reconstruction (no rads)
2. Psychosocial well-being and sexual well-being better with lumpectomy+rads https://t.co/tPh9Pt4gYx— JAMA Surgery (@JAMASurgery) April 14, 2022
Cohort Study: Intrauterine device-related uterine perforation incidence and risk.
6 Jun, 2022 | 10:59h | UTCIntrauterine device-related uterine perforation incidence and risk (APEX-IUD): a large multisite cohort study – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Although the risk for uterine perforation with IUD insertion 4 days to 6 weeks or less postpartum is nearly 7x that of insertion non-postpartum, perforation remains an incredibly rare event for all clinical time pointshttps://t.co/DPqgLAh1Dx
— The Lancet (@TheLancet) June 3, 2022
Cohort Study: Pregnancy outcomes in young women with youth-onset type 2 diabetes.
3 Jun, 2022 | 12:00h | UTC
Commentary on Twitter
Type 2 diabetes in youth is a severe disease.
Among 260 pregnancies reported in the TODAY study, 2/3rds with complications:
👉25% pregnancy loss
👉33% preterm birth
👉35% hypertension
👉27% large infantsNew prevention/treatment desperately neededhttps://t.co/SaMXAy4Xjz
— Dr. David Ludwig (@davidludwigmd) June 2, 2022
Cohort Study: Association of SARS-CoV-2 infection during pregnancy with maternal and perinatal outcomes.
3 Jun, 2022 | 11:55h | UTCAssociation of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes – JAMA
Maternal vaccination: a review of current evidence and recommendations.
3 Jun, 2022 | 11:40h | UTC
Commentary on Twitter
AJOG Expert Review: Maternal vaccination: a review of current evidence and recommendations – Placental transfer of IgG antibodies from maternal to fetal circulation https://t.co/yd3DQpwSoD pic.twitter.com/obicClLhzC
— AJOG (@AJOG_thegray) April 1, 2022