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M-A: Hypothermic vs. normothermic temperature control after cardiac arrest.

24 Jun, 2022 | 11:51h | UTC

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest – NEJM Evidence

Related:

ERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis – Critical Care

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine

Targeted Temperature Management for Cardiac Arrest Due to Non-shockable Rhythm: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Frontiers in Medicine

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine

 


Systematic Review: Parenteral Vitamin C in patients with severe infection.

24 Jun, 2022 | 11:49h | UTC

Parenteral Vitamin C in Patients with Severe Infection: A Systematic Review – NEJM Evidence

Related:

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit – New England Journal of Medicine

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis – Intensive Care Medicine

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA

 


New COVID drugs face delays as trials grow more difficult.

24 Jun, 2022 | 11:47h | UTC

New COVID drugs face delays as trials grow more difficult – Nature

 


Research must do no harm: new guidance addresses all studies relating to people.

24 Jun, 2022 | 11:46h | UTC

Research must do no harm: new guidance addresses all studies relating to people – Nature

See Guidance: Research Ethics – Nature Portfolio

 


An update on refractory hypertension.

24 Jun, 2022 | 11:44h | UTC

An Update on Refractory Hypertension – Current Hypertension Reports

 


Is shorter always better? The pros and cons of treating Gram-negative bloodstream infections with 7 days of antibiotics.

24 Jun, 2022 | 11:38h | UTC

Is shorter always better? The pros and cons of treating Gram-negative bloodstream infections with 7 days of antibiotics – JAC-Antimicrobial Resistance

 


Perspective | Four areas of health innovation boosted by the pandemic.

24 Jun, 2022 | 11:36h | UTC

Four areas of health innovation boosted by the pandemic – Nature Medicine

 

Commentary on Twitter

 


Cohort Study: COVID-19 trajectories among 57 million adults in England.

24 Jun, 2022 | 11:34h | UTC

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records – The Lancet Digital Health

News Release: Most comprehensive analysis of COVID-19 data reveals previously unattributed deaths – Health Data Research UK

 

Commentary from one of the authors on Twitter (thread – click for more)

 


EULAR/ACR points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases.

24 Jun, 2022 | 11:23h | UTC

The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated periodic syndrome, mevalonate kinase deficiency, and deficiency of the interleukin-1 receptor antagonist – Annals of Rheumatic Diseases

 


EULAR/PRES recommendations for vaccination of pediatric patients with autoimmune inflammatory rheumatic diseases.

24 Jun, 2022 | 11:17h | UTC

EULAR/PRES recommendations for vaccination of paediatric patients with autoimmune inflammatory rheumatic diseases: update 2021 – Annals of Rheumatic Diseases

 


ESPGHAN Position Paper: use of low-FODMAP diet in pediatric gastroenterology.

24 Jun, 2022 | 11:15h | UTC

An ESPGHAN Position Paper on the Use of Low-FODMAP Diet in Pediatric Gastroenterology – Pediatric Gastroenterology and Nutrition

 


Consensus Paper: Diagnosis and treat-to-target management of macrophage activation syndrome in children.

24 Jun, 2022 | 11:13h | UTC

Egyptian evidence-based consensus on clinical practice guidelines for the diagnosis and treat-to-target management of macrophage activation syndrome in children – Egyptian Rheumatology and Rehabilitation

 


Position Paper: Teleconsultation in respiratory medicine.

24 Jun, 2022 | 11:11h | UTC

Teleconsultation in respiratory medicine – A position paper of the Portuguese Pulmonology Society – Pulmonology

 


RCT: Effect of banded Roux-en-Y gastric bypass versus sleeve gastrectomy on diabetes remission at 5 years among patients with obesity and type 2 diabetes.

24 Jun, 2022 | 11:10h | UTC

Effect of Banded Roux-en-Y Gastric Bypass Versus Sleeve Gastrectomy on Diabetes Remission at 5 Years Among Patients With Obesity and Type 2 Diabetes: A Blinded Randomized Clinical Trial – Diabetes Care (link to abstract – $ for full-text)

 


Dysplastic recurrence after successful treatment for early Barrett’s neoplasia: development and validation of a prediction model.

24 Jun, 2022 | 11:07h | UTC

Dysplastic Recurrence After Successful Treatment for Early Barrett’s Neoplasia: Development and Validation of a Prediction Model – Gastroenterology

 


M-A: Benefits and harms of interventions with surgery compared to interventions without surgery for musculoskeletal conditions.

24 Jun, 2022 | 11:04h | UTC

Benefits and Harms of Interventions With Surgery Compared to Interventions Without Surgery for Musculoskeletal Conditions: A Systematic Review With Meta-analysis – Journal of Orthopaedic & Sports Physical Therapy

 


Hemorrhagic fever with renal syndrome: literature review, epidemiology, clinical picture and pathogenesis.

24 Jun, 2022 | 11:02h | UTC

Hemorrhagic Fever with Renal Syndrome: Literature Review, Epidemiology, Clinical Picture and Pathogenesis – Infections & Chemotherapy

 


Tips for avoiding common mistakes in out-of-hospital diagnosis of carbon monoxide poisoning.

24 Jun, 2022 | 10:57h | UTC

Tips for avoiding common mistakes in out-of-hospital diagnosis of carbon monoxide poisoning – Journal of Anesthesia, Analgesia and Critical Care

 


Cataract surgery: both eyes on the same day or on different days?

24 Jun, 2022 | 10:55h | UTC

Cataract surgery: both eyes on the same day or on different days? – Evidently Cochrane

Original Study: Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts – Cochrane Library

 


Systematic Review: Cortisol levels during acute illnesses in children and adolescents.

24 Jun, 2022 | 10:54h | UTC

Cortisol Levels During Acute Illnesses in Children and Adolescents: A Systematic Review – JAMA Network Open

 


M-A: Effect of different types of exercise in adult subjects with fibromyalgia.

24 Jun, 2022 | 10:52h | UTC

Effect of different types of exercise in adult subjects with fibromyalgia: a systematic review and meta-analysis of randomised clinical trials – Scientific Reports

 


RCT: Dextrose gel for neonates at risk with asymptomatic hypoglycemia.

24 Jun, 2022 | 10:50h | UTC

Dextrose Gel for Neonates at Risk With Asymptomatic Hypoglycemia: A Randomized Clinical Trial – Pediatrics (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Single-arm phase II study: EZH2 inhibitor tazemetostat in patients with relapsed or refractory, BAP1-inactivated malignant pleural mesothelioma.

24 Jun, 2022 | 10:49h | UTC

EZH2 inhibitor tazemetostat in patients with relapsed or refractory, BAP1-inactivated malignant pleural mesothelioma: a multicentre, open-label, phase 2 study – The Lancet Oncology (link to abstract – $ for full-text)

 


Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke.

24 Jun, 2022 | 10:48h | UTC

Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke – Science Advances

Commentary: Can Low-field Portable MRI Widen Access to Rapid Screening for Stroke? – Neurology Today

 


Longitudinal molecular profiling of circulating tumor cells in metastatic renal cell carcinoma.

24 Jun, 2022 | 10:46h | UTC

Longitudinal Molecular Profiling of Circulating Tumor Cells in Metastatic Renal Cell Carcinoma – Journal of Clinical Oncology (link to abstract – $ for full-text)

News Release: Non-invasive liquid biopsy tracks cancer treatment success in real time – University of Wisconsin–Madison

Commentary: Longitudinal Liquid Biopsy for Circulating Tumor Cells in Metastatic Renal Cell Carcinoma – The ASCO Post

 

Commentary on Twitter

 


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