Knee
M-A: Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis – although Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be most effective treatments, topical diclofenac 70-81 mg/day is safer and should be considered as first line treatment.
17 Oct, 2021 | 21:14h | UTCNews release: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital
Commentary: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News
Commentary on Twitter
Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be the most effective oral NSAIDs for knee and hip osteoarthritis pain and physical function, but might not be appropriate in the presence of comorbidities or for long term use, concludes #BMJResearchhttps://t.co/rrtX3BnQE5
— The BMJ (@bmj_latest) October 16, 2021
Guideline Synopsis: The Non-Surgical Management of Hip and Knee Osteoarthritis.
1 Oct, 2021 | 10:00h | UTC
Consensus paper: Clinical indications for image-guided interventional procedures in the musculoskeletal system—part V, knee.
23 Sep, 2021 | 09:59h | UTCSee other articles in the series: Consensus paper: Clinical indications for image-guided interventional procedures in the musculoskeletal system.
AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.
21 Sep, 2021 | 09:03h | UTCNews release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons
Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons
Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline
AAOS Guideline: Pharmacologic, physical, and cognitive pain alleviation for musculoskeletal extremity/pelvis surgery.
5 Aug, 2021 | 08:49h | UTCEvidence summary: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery
RCT: Among patients with prosthetic joint infection, antibiotic therapy for 6 weeks was NOT shown to be noninferior to antibiotic therapy for 12 weeks and resulted in a higher percentage of patients with unfavorable outcomes.
27 May, 2021 | 08:20h | UTCAntibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection – New England Journal of Medicine (link to abstract – $ for full-text)
M-A: Among patients undergoing total knee arthroplasty, glucocorticoid supplementation in periarticular infiltration analgesia is effective and does not increase complications or side effects.
21 May, 2021 | 08:22h | UTC
Consensus on pre-operative total knee replacement education and prehabilitation recommendations: a UK-based modified Delphi study
28 Apr, 2021 | 08:01h | UTC
Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients – this large observational study did not show an increased risk for venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or transient ischemic attacks, irrespective of patient high-risk status at baseline
28 Apr, 2021 | 07:59h | UTCSafety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients – Anesthesiology (link to abstract – $ for full-text)
Commentaries on Twitter
Our study online @_Anesthesiology today: safety of TXA in high-risk pts ➡️data from 500 hospitals shows no increased risks of VTE, MI, seizures, ischemic stroke or TIA. @HipKneeDoc @MountSinaiOrtho 🔗 https://t.co/za7SH8C7rj pic.twitter.com/J8hoW6stNm
— Jashvant Poeran (@jashvant_p) April 16, 2021
Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients @_Anesthesiology
👉TXA in high risk pts is not associated w/ venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or TIAshttps://t.co/DwZe0brJ9L pic.twitter.com/KGcRCftcOl
— Emily Sharpe, MD (@emilysharpe) April 22, 2021
M-A: Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery
17 Mar, 2021 | 02:23h | UTC
RCT: Early surgical reconstruction vs. rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture
10 Mar, 2021 | 08:17h | UTC
RCT: Among patients with knee osteoarthritis, high-intensity strength training was not associated with better outcomes compared with low-intensity strength training or an attention control
17 Feb, 2021 | 01:24h | UTCCommentary: No Benefit from High-Intensity Strength Training for Knee Osteoarthritis – NEJM Journal Watch
Commentary on Twitter
Hot from press: JAMA paper puts question mark on the effectiveness of both low- and high-intensity exercise for knee OA pain. Attention controls had similar improvement. Contextual effects and RTM phenomenon in OA may be powerful! https://t.co/EBrXZcvyXH@OARSInews @JAMA_current pic.twitter.com/880InW1Lag
— Martin Englund (@dr_englund) February 16, 2021
Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee OsteoarthritisThe START Randomized Clinical Trial
👀👀👇👇😳😳https://t.co/W6EQizkiAM pic.twitter.com/RViK36gjHv
— Physio Meets Science (@PhysioMeScience) February 16, 2021
Review: Diagnosis and treatment of hip and knee osteoarthritis
16 Feb, 2021 | 02:05h | UTCDiagnosis and Treatment of Hip and Knee Osteoarthritis: A Review – JAMA (free or a limited period)