Knee
M-A: Effectiveness of pharmacological-based interventions, including education and prescribing strategies, to reduce subacute pain after total hip or knee arthroplasty.
23 Jun, 2022 | 10:04h | UTC
Commentary on Twitter
A systematic review of RCTs looking at effectiveness of pharmacological interventions to ⬇️ pain following total hip/knee arthroplasty. Interventions involving multimodal non-opioid analgesia & education show positive effects on ⬇️ pain intensity. https://t.co/t2majwzHPz pic.twitter.com/HoybWv2VFO
— Pain Medicine Journal (@PainMedJournal) March 31, 2022
M-A: Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for diagnosing periprosthetic joint infections.
21 Jun, 2022 | 10:38h | UTC
M-A: Effect of intravenous dexamethasone on postoperative pain in patients undergoing total knee arthroplasty.
11 May, 2022 | 10:52h | UTC
M-A: Comparison of different strategies in revision arthroplasty of the knee with severe bone loss.
4 May, 2022 | 10:32h | UTC
RCT: Pulsed low-intensity ultrasonography does not provide symptom relief to patients with knee osteoarthritis.
3 May, 2022 | 10:47h | UTCCommentaries:
Pulsed low-intensity ultrasonography shows no benefit in knee OA – medwire News
Hopes Dashed for Novel Osteoarthritis Treatment — Noninvasive therapy looked like a sure winner until trial results came in – MedPage Today (free registration required)
Commentary on Twitter
Phase 2a RCT finds no benefit from pulsed low-intensity ultrasound in the treatment of knee osteoarthritis in veterans. https://t.co/dEqjkqCadj pic.twitter.com/0qwKQ3rfkD
— JAMA Network Open (@JAMANetworkOpen) March 8, 2022
RCT: Early surgery vs. exercise and education for meniscal tears in young adults.
25 Apr, 2022 | 00:51h | UTCEarly Surgery or Exercise and Education for Meniscal Tears in Young Adults – NEJM Evidence
Commentary:
Early Surgery Not Superior for Meniscal Tears in Young Adults – HealthDay
Commentary on Twitter
DREAM trial: In this pragmatic #RCT in active young adults with meniscal tears, early meniscal surgery was not superior to a strategy of supervised exercise therapy and education with the option of later surgery. @STSkou #OrthoTwitter #SurgTwitter https://t.co/TrnEUG98wP pic.twitter.com/V66ZbknksM
— NEJM Evidence (@NEJMEvidence) January 25, 2022
RCT: Among patients waiting for total knee arthroplasty with a BMI above 35, bariatric surgery before the procedure was associated with reduced risk of complications.
18 Apr, 2022 | 09:52h | UTCCommentary: Bariatric Surgery Before TKA Cuts Complications in Obese Patients – HealthDay
Commentary on Twitter
In this RCT, bariatric surgery before knee replacement (TKA) reduced the risk of complications in TKA in adults <65y with class II obesity scheduled to undergo TKA; 30% had sufficient symptom improvement to decline TKA altogether. https://t.co/qyhl0eIV2o
— JAMA Network Open (@JAMANetworkOpen) April 14, 2022
RCT: In patients undergoing knee replacement surgery, the administration of periarticular liposomal bupivacaine did not improve postoperative recovery or pain compared with bupivacaine hydrochloride alone.
13 Apr, 2022 | 10:16h | UTC
RCT: Effect of intramuscular vs. intra-articular glucocorticoid injection on pain among adults with knee osteoarthritis.
7 Apr, 2022 | 08:35h | UTC
Commentary on Twitter
This RCT found IM steroid injections were inferior to intrarticular injections for reducing pain in patients with knee osteoarthritis at 4 weeks but were noninferior at 8 and 24 weeks after injection. https://t.co/opq1C2BP8c pic.twitter.com/ucx4lvRDJQ
— JAMA Network Open (@JAMANetworkOpen) April 5, 2022
M-A: Impact of enhanced recovery pathways on safety and efficacy of hip and knee arthroplasty.
1 Apr, 2022 | 08:31h | UTCRelated:
Review: Enhanced recovery after surgery for major orthopedic surgery.
Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (some guidelines are free)
International consensus meeting on venous thromboembolism in orthopedic surgery.
28 Mar, 2022 | 09:45h | UTCHomepage: International Consensus Meeting on Venous Thromboembolism (free articles for a limited period)
Recommendations from the ICM-VTE: General
Recommendations from the ICM-VTE:: Foot & Ankle
Recommendations from the ICM-VTE: Hand & Wrist
Recommendations from the ICM-VTE: Hip & Knee
Recommendations from the ICM-VTE: Oncology
Recommendations from the ICM-VTE: Pediatric
Recommendations from the ICM-VTE: Shoulder & Elbow
Recommendations from the ICM-VTE: Sports
Recommendations from the ICM-VTE: Trauma
Recommendations from the ICM-VTE: Spine
RCT: In patients with knee osteoarthritis, prehabilitation before total knee replacement did not improve functional outcomes.
25 Mar, 2022 | 08:32h | UTCCommentary: Prehabilitation May Not Improve Knee Replacement Results – Medscape (free registration required)
Commentary on Twitter
In this randomized clinical trial that included 262 participants, prehabilitation for knee osteoarthritis did not improve functional outcomes in total knee replacement. Findings question the usefulness of prehabilitation before total knee replacement. https://t.co/vsMxQ8PYJ7
— JAMA Network Open (@JAMANetworkOpen) March 9, 2022
Meta-analysis of randomized trials: benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery.
10 Mar, 2022 | 10:48h | UTC
Commentary on Twitter
Led by Maura Marcucci, network meta-analysis of of 68 surgery #RCT's (45,445 patients; mainly #ortho) found that #DOAC's & #LMWH reduce #VTE but probably increase major bleeding to a similar extent. DOACs probably prevent symptomatic VTE more than #LMWH. https://t.co/7vrgVpfD3s pic.twitter.com/H5Fuq7p1hi
— Kari Tikkinen (@KariTikkinen) March 9, 2022
Updated guideline summary introduces new recommendations for use of medications around total hip and knee replacement.
10 Mar, 2022 | 10:45h | UTCGuideline Summary (full guideline not available yet): 2022 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty – American College of Rheumatology
Systematic Review: Arthroscopic surgery provides little or no clinically important benefit for patients with degenerative knee disease.
4 Mar, 2022 | 09:53h | UTCSummary: Arthroscopic surgery for degenerative knee disease – Cochrane Library
Related:
Guideline: Arthroscopic Meniscal Surgery
Study: Adverse Outcomes After Arthroscopic Partial Meniscectomy
Prevalence trends of site-specific osteoarthritis from 1990 to 2019: findings from the Global Burden of Disease Study 2019.
3 Mar, 2022 | 08:27h | UTCNews Release: Study reveals a persistently high burden of osteoarthritis across the globe – Wiley
Cost-effectiveness of physical therapy vs. intra-articular glucocorticoid injection for knee osteoarthritis: a secondary analysis from a randomized clinical trial.
16 Feb, 2022 | 08:24h | UTC
RCT: In patients undergoing total knee arthroplasty, two doses of dexamethasone reduced pain intensity and consumption of morphine.
11 Feb, 2022 | 08:41h | UTC
M-A: Patients generally may return to driving 4 weeks after hip arthroscopy and 6 weeks after knee arthroscopy.
10 Feb, 2022 | 08:31h | UTC
Commentary on Twitter
Patients are generally safe to drive *4 weeks* after hip arthroscopy and *6 weeks* after knee arthroscopy. Meta-Analysis from Palma et al in ASMAR this month gives us the evidence!
Is it time to revise your instructions for your patients? 🤔https://t.co/Bcg12tX0MM pic.twitter.com/wAhJx2vS8a
— Arthroscopy Journal (@ArthroscopyJ) October 20, 2021
Hyaluronic acid injections have increased for knee arthritis in the US, despite guideline recommendations against their use.
4 Feb, 2022 | 08:32h | UTCHyaluronic Acid Injections for Knee Osteoarthritis: Has Utilization Among Medicare Beneficiaries Changed Between 2012 and 2018? – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)
News Release: Hyaluronic acid injections have increased for knee arthritis – despite recommendations against their use
Related Guideline: Treatment of Osteoarthritis of the Knee: Evidence-Based Guideline, 2nd Edition – Journal of the American Academy of Orthopaedic Surgeons
Cluster randomized trial: no added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis.
16 Jan, 2022 | 22:59h | UTC
Consensus Statement: Treatment of combined injuries to the anterior cruciate ligament and the medial collateral ligament complex.
17 Dec, 2021 | 08:38h | UTC
Management of patellar tendinopathy: a systematic review and network meta-analysis of randomized studies.
16 Dec, 2021 | 08:35h | UTC
Systematic Review | Prehabilitation and rehabilitation for major joint replacement.
21 Nov, 2021 | 22:41h | UTCSee also:
M-A: Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis – although Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be most effective treatments, topical diclofenac 70-81 mg/day is safer and should be considered as first line treatment.
17 Oct, 2021 | 21:14h | UTCNews release: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital
Commentary: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News
Commentary on Twitter
Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be the most effective oral NSAIDs for knee and hip osteoarthritis pain and physical function, but might not be appropriate in the presence of comorbidities or for long term use, concludes #BMJResearchhttps://t.co/rrtX3BnQE5
— The BMJ (@bmj_latest) October 16, 2021