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Knee

M-A: Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis – although Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be most effective treatments, topical diclofenac 70-81 mg/day is safer and should be considered as first line treatment.

17 Oct, 2021 | 21:14h | UTC

Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis – The BMJ

News release: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital

Commentary: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News

 

Commentary on Twitter

 


Guideline Synopsis: The Non-Surgical Management of Hip and Knee Osteoarthritis.

1 Oct, 2021 | 10:00h | UTC

Synopsis of the 2020 US Department of Veterans Affairs/US Department of Defense Clinical Practice Guideline: The Non-Surgical Management of Hip and Knee Osteoarthritis – Mayo Clinic Proceedings

 


Consensus paper: Clinical indications for image-guided interventional procedures in the musculoskeletal system—part V, knee.

23 Sep, 2021 | 09:59h | UTC

Clinical indications for image-guided interventional procedures in the musculoskeletal system: a Delphi-based consensus paper from the European Society of Musculoskeletal Radiology (ESSR)—part V, knee – European Radiology

See other articles in the series: Consensus paper: Clinical indications for image-guided interventional procedures in the musculoskeletal system.

 


AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.

21 Sep, 2021 | 09:03h | UTC

News release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons

Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons

Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline

 


AAOS Guideline: Pharmacologic, physical, and cognitive pain alleviation for musculoskeletal extremity/pelvis surgery.

5 Aug, 2021 | 08:49h | UTC

Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery – American Academy of Orthopaedic Surgeons

Evidence summary: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery

News release: Clinical Practice Guideline and Appropriate Use Criteria for the Evaluation of Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery

 


RCT: Among patients with prosthetic joint infection, antibiotic therapy for 6 weeks was NOT shown to be noninferior to antibiotic therapy for 12 weeks and resulted in a higher percentage of patients with unfavorable outcomes.

27 May, 2021 | 08:20h | UTC

Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection – New England Journal of Medicine (link to abstract – $ for full-text)

 


M-A: Among patients undergoing total knee arthroplasty, glucocorticoid supplementation in periarticular infiltration analgesia is effective and does not increase complications or side effects.

21 May, 2021 | 08:22h | UTC

The Efficacy and Safety of Glucocorticoid on Periarticular Infiltration Analgesia in Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – The Journal of Arthroplasty

 


Consensus on pre-operative total knee replacement education and prehabilitation recommendations: a UK-based modified Delphi study

28 Apr, 2021 | 08:01h | UTC

Consensus on pre-operative total knee replacement education and prehabilitation recommendations: a UK-based modified Delphi study – BMC Musculoskeletal Diseases

 


Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients – this large observational study did not show an increased risk for venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or transient ischemic attacks, irrespective of patient high-risk status at baseline

28 Apr, 2021 | 07:59h | UTC

Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients – Anesthesiology (link to abstract – $ for full-text)

 

Commentaries on Twitter

 


M-A: Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery

17 Mar, 2021 | 02:23h | UTC

Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery: An abridged version of a Cochrane systematic review and meta-analysis – The Bone & Joint Journal

 


RCT: Early surgical reconstruction vs. rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture

10 Mar, 2021 | 08:17h | UTC

Early surgical reconstruction versus rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture: COMPARE randomised controlled trial – The BMJ

 


RCT: Among patients with knee osteoarthritis, high-intensity strength training was not associated with better outcomes compared with low-intensity strength training or an attention control

17 Feb, 2021 | 01:24h | UTC

Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis: The START Randomized Clinical Trial – JAMA

Commentary: No Benefit from High-Intensity Strength Training for Knee Osteoarthritis – NEJM Journal Watch

 

Commentary on Twitter

 


Review: Diagnosis and treatment of hip and knee osteoarthritis

16 Feb, 2021 | 02:05h | UTC

Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review – JAMA (free or a limited period)

 


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