Transplantation – Kidney
Guideline | Management of kidney transplant patients with HLA antibodies.
31 Aug, 2022 | 11:47h | UTC
RCT: Effect of perioperative dexmedetomidine on delayed graft function following a donation-after-cardiac-death kidney transplant.
7 Jun, 2022 | 10:55h | UTC
Commentary on Twitter
In this RCT, 24-hour dexmedetomidine infusion, started immediately after induction of & in addition to standard anesthesia, reduced the incidence of delayed graft function vs placebo, following a donation-after-cardiac-death kidney transplantation. https://t.co/cmX1IEZdVX
— JAMA Network Open (@JAMANetworkOpen) June 3, 2022
M-A: Risks for donors associated with living kidney donation.
31 May, 2022 | 11:23h | UTCRisks for donors associated with living kidney donation: meta-analysis – British Journal of Surgery
Commentary from the author on Twitter (thread – click for more)
#DiversityAndInclusion 🚺🚹when counseling #Living #Kidney #Donors: our meta-analysis on the #risks stratified according to donor demographic characteristics has just been published @BJSurgery 🔗https://t.co/LtXpPeykiM @MichaelNozdrin @lisetpengel @transplantev 🧵1/7 pic.twitter.com/WszUiTAd1Q
— Maria Irene Bellini MD, PhD, FEBS (@mirenebellini1) May 26, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Results of two cases of pig-to-human kidney xenotransplantation.
19 May, 2022 | 11:11h | UTCResults of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Genetically modified pig kidney xenografts were transplanted into two brain-dead human recipients. The xenografts functioned immediately, showed no evidence of acute rejection over a period of 54 hours. https://t.co/gWlpX1dCTC pic.twitter.com/Zp5XdA4QH5
— NEJM (@NEJM) May 18, 2022
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.
29 Apr, 2022 | 10:51h | UTC
Commentary on Twitter
🆕💥Review Article @ASHE_Journal
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them #IDTwitter #medtwitter #TwitteRx #MedEd https://t.co/ToPLQXtC4r pic.twitter.com/pZQWWb3ZSx— Antibiotic Steward Bassam Ghanem🆔🔥 (@ABsteward) April 28, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
Opinion: Moving xenotransplantation research into human trials will require adjusting our expectations, researchers say.
6 Apr, 2022 | 09:59h | UTCRelated:
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight.
In 1st, US surgeons transplant pig heart into human patient.
M-A: The impact of cold ischemia time on outcomes of living donor kidney transplantation.
24 Mar, 2022 | 08:33h | UTC
Editorial: Pig-to-human transplants take a leap toward reality.
22 Mar, 2022 | 08:31h | UTCPig-to-human transplants take a leap toward reality – Nature Medicine
M-A: Survival for waitlisted kidney failure patients receiving transplantation vs. remaining on waiting list.
2 Mar, 2022 | 08:46h | UTC
In a series of simultaneous pancreas and kidney transplantation cases, long-term data demonstrated that patient and graft survival were equivalent for conventional donation after circulatory death (DCD) vs. donation after brainstem death. The utilization of DCD pancreases may expand the donor pool with comparable results to DBD transplantation.
7 Feb, 2022 | 08:24h | UTC
Review: Post-transplant cardiovascular disease.
7 Feb, 2022 | 08:20h | UTCPost-Transplant Cardiovascular Disease – Clinical Journal of the American Society of Nephrology
Thinking outside the box: novel kidney protective strategies in kidney transplantation.
7 Feb, 2022 | 08:16h | UTC
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight.
25 Jan, 2022 | 09:09h | UTCAfter a flurry of firsts, xenotransplantation is suddenly back in the spotlight – STAT
Related: In 1st, US surgeons transplant pig heart into human patient.
RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.
7 Dec, 2021 | 08:37h | UTC
Recurrent Glomerular Disease after Kidney Transplantation: Diagnostic and Management Dilemmas.
28 Oct, 2021 | 09:43h | UTC
Commentary on Twitter
Recurrent glomerular disease after kidney transplant remains an important cause of allograft failure. This Review focuses on clinical dilemmas encountered by physicians in managing recurrent glomerular disease https://t.co/QGZOjH7qyP
— CJASN (@CJASN) October 27, 2021
In a major scientific advance, a pig kidney is successfully transplanted into a human.
21 Oct, 2021 | 09:52h | UTCIn a major scientific advance, a pig kidney is successfully transplanted into a human – NPR
Long-Term Immunosuppression Management: Opportunities and Uncertainties.
7 Oct, 2021 | 10:15h | UTC
Commentary on Twitter
Long-Term Immunosuppression Management: Opportunities and Uncertainties. A Review evaluates the current state of maintenance immunosuppression in kidney transplant recipients and discusses areas of opportunity and uncertainty in their long-term use. https://t.co/8yWp4PVD7t
— CJASN (@CJASN) August 16, 2021
FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now.
16 Aug, 2021 | 01:22h | UTCCommentaries:
CDC, FDA recommend COVID booster for immune-compromised – CIDRAP
FDA authorizes additional dose of Covid-19 vaccine for the immunocompromised – STAT
Covid booster: US approves third jab for the immunocompromised – BBC
CDC Panel Recommends 3rd Vaccine Dose For Immunocompromised People – NPR
6 Things To Know If You’re Immunocompromised And Considering A 3rd Shot – NPR
CDC recommends third Covid-19 vaccine dose for certain immunocompromised people – CNN
Commentary on Twitter
The Infectious Diseases Society of America (IDSA) supports the @FDA and @CDCgov's decision to authorize a supplemental vaccine dose for immunocompromised patients.
Read our statement: https://t.co/odzzSgIxnY pic.twitter.com/4PZfUwpjhM
— IDSA (@IDSAInfo) August 13, 2021
RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients.
12 Aug, 2021 | 09:56h | UTCEditorial: Third Time’s a Charm — Covid-19 Vaccine Hope for Solid-Organ Transplant Recipients
Related:
[Preprint] 3rd AstraZeneca shot gives strong immunity.
Commentaries on Twitter
..1st randomized trial results of 3rd doses of Moderna vax for 120 people with organ transplants: month 4, their minimum anti-RBD antibody levels were 55% for 3rd dose vs 18% (still increasing a little in the placebo group). No cases of acute rejection https://t.co/BcfeyUEhx5 #IC
— Hilda Bastian, PhD (@hildabast) August 11, 2021
The authors conclude that a third-dose booster of mRNA-1273 vaccine should be considered for transplant recipients. https://t.co/Q3gakSaNjd pic.twitter.com/CMN8f7cq29
— NEJM (@NEJM) August 11, 2021
Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.
26 Jul, 2021 | 02:54h | UTCCommentary: Case Mounts for COVID Vaccine Boosters in Kidney Transplant Recipients – MedPage Today (free registration required)
Related:
[Preprint] 3rd AstraZeneca shot gives strong immunity.
Commentary on Twitter
JUST PUBLISHED @JAMANetwork
✔️N=159 kidney #transplant recipients
✔️3rd dose of #mRNA #Moderna #vaccine induced a #serologic response in 49% of kidney transplant recipients who did not respond after 2 doseshttps://t.co/NCDyraI98x#RealTimeCOVID19 @IDSAInfo @HIV_TID @AST_info— COVID-19 Real-Time Learning Network (RTLN) (@RealTimeCOVID19) July 24, 2021
RCT: Similar outcomes with mycophenolate mofetil vs. azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression.
29 Jun, 2021 | 09:50h | UTC
Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients can improve the immunogenicity of the vaccine.
24 Jun, 2021 | 10:32h | UTC
Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.
15 Jun, 2021 | 08:59h | UTCCommentaries: For Transplant Recipients, Third Time May Be the Charm for Better COVID Vaccine Protection – Hopkins Medicine AND Extra COVID Vaccine May Help Protect Transplant Patients – Associated Press
Commentary on Twitter
Our report about 3rd vaccine doses in transplant patients is published! "It is encouraging that antibody titers increased after the 3rd dose in 1/3 of patients who had negative antibody titers and in all patients who had low-positive antibody titers"https://t.co/6XElwyIdAa
— Dorry Segev (@Dorry_Segev) June 14, 2021
Cohort study shows inadequate antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients.
6 May, 2021 | 09:01h | UTC
Commentary on Twitter
The studies of mRNA vax in people with transplants are getting bigger: still the same message. Some protection, but not enough. This time, 308 people with kidney transplants in Israel, BNT-Pfizer vaccine https://t.co/Otvt8F11my
— Hilda Bastian, PhD (@hildabast) May 6, 2021
Organ transplant recipients remain vulnerable to Covid-19 even after second vaccine dose.
6 May, 2021 | 09:03h | UTCOriginal Study: Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients – JAMA