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AHA/ASA Guideline for the management of patients with aneurysmal subarachnoid hemorrhage

29 May, 2023 | 11:16h | UTC

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke

Top Things to Know: 2023 Aneurysmal Subarachnoid Hemorrhage Guideline – American Heart Association


Commentary on Twitter


Guideline | Targeted temperature management in intracerebral, subarachnoid hemorrhage and acute ischemic stroke

29 May, 2023 | 10:48h | UTC

Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: updated consensus guideline recommendations by the Neuroprotective Therapy Consensus Review (NTCR) group – British Journal of Anaesthesia


Guideline | Assessment and early management of head injury

23 May, 2023 | 13:11h | UTC

Head injury: assessment and early management – NICE

Commentary: NICE head injury guidelines 2023: Now who do we scan? – St Emilyn’s


Neurosurgical interventions for cerebral metastases of solid tumors

11 May, 2023 | 11:48h | UTC

Neurosurgical Interventions for Cerebral Metastases of Solid Tumors – Deutsches Ärzteblatt International

Review | Early switch to oral antimicrobials in brain abscess

10 May, 2023 | 15:55h | UTC

Early switch to oral antimicrobials in brain abscess: A narrative review – Clinical Microbiology and Infection


ESTES recommendation on thoracolumbar spine fractures

10 May, 2023 | 15:40h | UTC

ESTES recommendation on thoracolumbar spine fractures – European Journal of Trauma and Emergency Surgery

RCT | Craniotomy and decompressive craniectomy yield comparable outcomes in acute subdural hematoma

2 May, 2023 | 13:51h | UTC

Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: International study recommends replacing skull section after treatment for a brain bleed – University of Cambridge


Commentary on Twitter


M-A | Pain management interventions for the treatment of chronic low back pain

2 May, 2023 | 13:26h | UTC

Pain Management Interventions for the Treatment of Chronic Low Back Pain: A Systematic Review and Meta-Analysis – The Clinical Journal of Pain


M-A | Efficacy of erector spinae plane block for postoperative analgesia lumbar surgery

26 Apr, 2023 | 13:53h | UTC

Efficacy of erector spinae plane block for postoperative analgesia lumbar surgery: a systematic review and meta-analysis – BMC Anesthesiology


M-A | Surgical versus non-surgical treatment for sciatica

25 Apr, 2023 | 14:39h | UTC

Surgical versus non-surgical treatment for sciatica: systematic review and meta-analysis of randomised controlled trials – The BMJ

Editorial: Early surgery for sciatica – The BMJ

News Release: Surgery for sciatica reduces leg pain and disability, but benefits are short-lived – University of Oxford


Commentary on Twitter


Brief Review | Management of pituitary incidentalomas

25 Apr, 2023 | 14:14h | UTC

Management of pituitary incidentalomas – Clinical Medicine Journal


Prehospital guidelines for the management of traumatic brain injury

24 Apr, 2023 | 13:45h | UTC

Prehospital Guidelines for the Management of Traumatic Brain Injury – 3rd Edition – Prehospital Emergency Care


RCT | Stereotactic radiosurgery vs. conventional radiotherapy for localized vertebral metastases of the spine

24 Apr, 2023 | 13:37h | UTC

Stereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)

Audio interview: Radiosurgery of Spine Metastasis—NRG/RTOG 0631 RCT Final Results – JAMA


Commentary on Twitter


Cohort Study | Prehospital end-tidal CO2 levels and mortality in suspected severe traumatic brain injury patients

24 Apr, 2023 | 13:35h | UTC

Association between prehospital end-tidal carbon dioxide levels and mortality in patients with suspected severe traumatic brain injury – Intensive Care Medicine

Editorial: Prehospital ventilation targets in severe traumatic brain injury – Intensive Care Medicine


Commentary on Twitter


Cohort Study | Major cardiovascular events after spontaneous intracerebral hemorrhage by hematoma location

12 Apr, 2023 | 13:13h | UTC

Major Cardiovascular Events After Spontaneous Intracerebral Hemorrhage by Hematoma Location – JAMA Network Open

Invited Commentary: Major Adverse Cardiovascular Events After Intracerebral Hemorrhage—It’s All About Location, Location, Location – JAMA Network Open


RCT | Drain usage may increase the length of hospital stay following lumbar arthrodesis

31 Mar, 2023 | 13:18h | UTC

Wound drain in lumbar arthrodesis for degenerative disease: an experimental, multicenter, randomized controlled trial – The Spine Journal

Commentary: Wound drains increase hospital los after lumbar surgery? – Orthopedics This Week


Expanding Organ Usage: UK study finds organs from patients with a primary brain tumor are a viable option

27 Mar, 2023 | 13:27h | UTC

Summary: A national cohort study in the UK investigated the risk of cancer transmission from deceased donors with primary brain tumors to organ recipients. The study found no cases of brain tumor transmission among 778 transplants from 282 donors with primary brain tumors, including 262 from donors with high-grade tumors. Organ transplant survival was equivalent to that in matched controls, and some organs from donors with high-grade tumors were less likely to be transplanted.

The results suggest that the risk of cancer transmission in transplants from deceased donors with primary brain tumors is lower than previously thought. Furthermore, the study indicated that donors with brain tumors provided good-quality organs with favorable risk markers and excellent transplant outcomes. Some organs from donors with high-grade tumors were underutilized, indicating a possible aversion by transplant clinicians or patients to use these organs.

These findings imply that it may be possible to safely expand organ usage from donors with primary brain tumors without negatively impacting outcomes, potentially benefiting many patients waiting for a transplant. Although this might lead to a slight rise in transplant numbers in the UK, the findings may hold particular significance for nations with stricter guidelines, such as the United States. The study’s findings can help transplant clinicians discuss the risks and benefits of accepting organ offers from such donors.

Article: Organ Transplants From Deceased Donors With Primary Brain Tumors and Risk of Cancer Transmission – JAMA Surgery


Cohort Study | Functional recovery, symptoms, and quality of life 1 to 5 years after traumatic brain injury

24 Mar, 2023 | 12:52h | UTC

Functional Recovery, Symptoms, and Quality of Life 1 to 5 Years After Traumatic Brain Injury – JAMA Network Open


Review | Neuromonitoring in critically ill patients

20 Mar, 2023 | 13:18h | UTC

Neuromonitoring in Critically Ill Patients – Critical Care Medicine (free for a limited period)

Related: The importance of neuromonitoring in non-brain injured patients – Critical Care


Review | Neurogenic shock: definition, identification, and management in the ED

20 Mar, 2023 | 13:09h | UTC

Neurogenic Shock: Definition, Identification, and Management in the ED – emDocs


M-A | Endoscopic surgery for spontaneous supratentorial intracerebral hemorrhage

16 Mar, 2023 | 13:04h | UTC

Endoscopic surgery for spontaneous supratentorial intracerebral haemorrhage: A systematic review and meta-analysis – Frontiers in Neurology


Global validation of the AO Spine Upper Cervical Injury Classification

16 Mar, 2023 | 12:58h | UTC

Global Validation of the AO Spine Upper Cervical Injury Classification – Spine


Consensus Recommendations | Spinal tumors

9 Mar, 2023 | 14:15h | UTC

Spinal tumours: recommendations of the Polish Society of Spine Surgery, the Polish Society of Oncology, the Polish Society of Neurosurgeons, the Polish Society of Oncologic Surgery, the Polish Society of Oncologic Radiotherapy, and the Polish Society of Orthopaedics and Traumatology – European Spine Journal


SR | Spinal cord stimulation for low back pain provides no sustained clinical benefits compared to placebo

9 Mar, 2023 | 14:12h | UTC

Summary: Spinal cord stimulation (SCS) is a surgical procedure used to treat persistent low back pain by sending electrical signals via implanted electrodes into the spinal cord. The review included 13 studies (randomized controlled trials and cross‐over trials) with 699 participants.

Most of the studies were focused on short-term effects (less than one month), but the review found it is uncertain whether spinal cord stimulation can improve outcomes in the immediate term compared with placebo. At six months, SCS probably does not improve back or leg pain, function, or quality of life compared with placebo, with moderate certainty of evidence. Adverse events were also reported, including infections, neurological damage, and lead migration requiring repeated surgery.

The review concluded that the data does not support the use of SCS to manage low back pain outside a clinical trial. Current evidence suggests SCS probably does not have sustained clinical benefits that would outweigh the costs and risks of this surgical intervention.

Article: Spinal cord stimulation for low back pain – Cochrane Library

Summary: Spinal cord stimulation for low back pain – Cochrane Library


Commentary from the author on Twitter


Cohort Study | Lifetime traumatic brain injury and cognitive domain deficits in late life

2 Mar, 2023 | 12:45h | UTC

Lifetime Traumatic Brain Injury and Cognitive Domain Deficits in Late Life: The PROTECT-TBI Cohort Study – Journal of Neurotrauma (link to abstract – you can try this link for full-text)

News Release: Three or more concussions linked with worse brain function in later life – University of Exeter


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