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Neurosurgery

Tranexamic acid after traumatic brain injury: Exploratory analysis combining data from CRASH-2 and CRASH-3 trials suggests reduced mortality

13 Nov, 2020 | 09:21h | UTC

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial – Critical Care

Commentary: New analysis combining data from the world’s largest trauma trials provides compelling evidence that rapid tranexamic acid treatment saves lives – London School of Hygiene & Tropical Medicine

 

Commentary on Twitter

 


Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus

13 Nov, 2020 | 09:19h | UTC

Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus – Intensive Care Medicine

 


Review: Management of common postoperative complications

4 Nov, 2020 | 09:26h | UTC

Management of Common Postoperative Complications – Mayo Clinic Proceedings

 


Meta-analysis: Efficacy and safety of tranexamic acid in acute traumatic brain injury

22 Oct, 2020 | 09:31h | UTC

Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials – Intensive Care Medicine

 

Commentary on Twitter

 


Case report: Cerebrospinal fluid leak after nasal swab testing for Covid-19

2 Oct, 2020 | 09:22h | UTC

Cerebrospinal Fluid Leak After Nasal Swab Testing for Coronavirus Disease 2019 – JAMA Internal Medicine

 

C0mmentary on Twitter

 


NICE Guideline: Low back pain and sciatica in over 16s

23 Sep, 2020 | 14:41h | UTC

Low back pain and sciatica in over 16s: assessment and management – National Institute for Health and Care Excellence

 


Randomized trial: Out-of-hospital tranexamic acid does not improve neurologic outcomes in patients with traumatic brain injury

9 Sep, 2020 | 09:20h | UTC

Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury – JAMA

Editorial: Out-of-Hospital Tranexamic Acid for Traumatic Brain Injury

 

Commentary on Twitter

 


Consensus recommendations on the prehospital care of the injured athlete with a suspected catastrophic cervical spine injury

21 Aug, 2020 | 02:16h | UTC

Consensus Recommendations on the Prehospital Care of the Injured Athlete With a Suspected Catastrophic Cervical Spine Injury – Clinical Journal of Sports Medicine

 


Guidelines for the management of severe traumatic brain injury: 2020 update of the decompressive craniectomy recommendations

10 Aug, 2020 | 01:46h | UTC

Guidelines for the Management of Severe Traumatic Brain Injury: 2020 Update of the Decompressive Craniectomy Recommendations – Neurosurgery

 


Cerebral Cavernous Malformation: What a Practicing Clinician Should Know

29 Jun, 2020 | 08:53h | UTC

Cerebral Cavernous Malformation: What a Practicing Clinician Should Know – Mayo Clinic Proceedings

 


Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients

11 Jun, 2020 | 09:21h | UTC

Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients – Neurocritical Care

Source: Critical Care Reviews

 


Framingham Heart Study: Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage

10 Jun, 2020 | 04:42h | UTC

Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016 – JAMA Neurology (free for a limited period)

Commentary: Stroke bleeds in the brain not decreasing, Framingham study finds – University of Texas Health Science Center at San Antonio

 


Review: Minimizing SARS-CoV-2 Exposure When Performing Surgical Interventions

28 May, 2020 | 09:42h | UTC

Minimizing SARS-CoV-2 exposure when performing surgical interventions during the covid-19 pandemic – Journal of NeuroInterventional Surgery

 


Analysis of Traumatic Brain Injury Lesions on Head CT Using Deep Learning

26 May, 2020 | 09:23h | UTC

Multiclass semantic segmentation and quantification of traumatic brain injury lesions on head CT using deep learning: an algorithm development and multicentre validation study – The Lancet Digital Health

Commentaries: Deep learning: a turning point in acute neurology – The Lancet Digital Health

AI successfully used to identify different types of brain injuries – University of Cambridge AND Deep learning automatically measures key features of TBI – Health Imaging

 


Randomized Trial: Beta-Blocker Therapy Promising in Severe Traumatic Brain Injury

29 Apr, 2020 | 04:47h | UTC

Beta-Blocker Therapy in Severe Traumatic Brain Injury: A Prospective Randomized Controlled Trial – World Journal of Surgery

Related Meta-Analysis: Beta-Blockers and Traumatic Brain Injury: A Systematic Review and Meta-Analysis – Annals of Surgery

“We recommend further high-quality trials to answer questions about the mechanisms of action, effectiveness on subgroups, dose-response, length of therapy, functional outcome, and quality of life after β-blocker use for TBI” (from the 2017 meta-analysis above)

 


Review: Surgery for Spontaneous Intracerebral Hemorrhage

10 Mar, 2020 | 10:21h | UTC

Surgery for spontaneous intracerebral hemorrhage – Critical Care (free)

 


[Abstract Only] Randomized Trial: Hippocampal Avoidance During Whole-Brain Radiotherapy for Patients with Brain Metastases

10 Mar, 2020 | 10:17h | UTC

Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001 – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentaries: Hippocampal avoidance during WBRT reduces risks on NRG Oncology trial – NRG Oncology (free) AND ‘Practice-Changing’ Study on WBRT for Patients With Brain Mets – Medscape (free registration required)

 


Clinical Update – Preventing Surgical Site Infections: Looking Beyond the Current Guidelines

23 Feb, 2020 | 22:21h | UTC

Preventing Surgical Site Infections: Looking Beyond the Current Guidelines – JAMA (free for a limited period)

Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control (free) AND Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines – World Journal of Emergency Surgery (free)

 


Cohort Study: Maximal Extent of Resection of Contrast-Enhanced and Non–Contrast-Enhanced Tumor and Survival in Patients with Glioblastoma

7 Feb, 2020 | 08:09h | UTC

Association of Maximal Extent of Resection of Contrast-Enhanced and Non–Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma – JAMA Oncology (free for a limited period)

Commentaries: A Common Rule for Resection of Glioblastoma in the Molecular Era – JAMA Oncology (free) AND Brain tumor surgery that pushes boundaries boosts patients survival – University of California (free) AND More aggressive surgery may improve brain cancer survival – UPI (free)

 


What is New in Decompressive Craniectomy in Neurological Emergencies: The Good, the Bad and the Ugly

31 Jan, 2020 | 01:28h | UTC

What is new in decompressive craniectomy in neurological emergencies: the good, the bad and the ugly – Intensive Care Medicine (free for a limited period)

Related Systematic Review: Decompressive Craniectomy for the Treatment of High Intracranial Pressure in Closed Traumatic Brain Injury – Cochrane Library (free article, guideline and randomized trial)

 


Consensus Statement: A Management Algorithm for Adult Patients with Both Brain Oxygen and Intracranial Pressure Monitoring

26 Jan, 2020 | 22:50h | UTC

A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC) – Intensive Care Medicine (free)

 


[Abstract Only] Long-term Results of Prenatal Repair of Myelomeningocele and School-age Functional Outcomes

26 Jan, 2020 | 22:30h | UTC

Prenatal Repair of Myelomeningocele and School-age Functional Outcomes – Pediatrics (link to abstract – $ for full-text)

Original Study: A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele – New England Journal of Medicine (free)

Commentaries: Fetal surgery for spina bifida makes a huge difference 10 years later – News Medical (free) AND Benefits of fetal surgery to repair spina bifida persist through school age – NIH News Releases (free)

Related: Guidelines For Pediatric Myelomeningocele – Congress of Neurological Surgeons (free)

 


Expert Consensus on the Management of Brain Arteriovenous Malformations

14 Jan, 2020 | 00:24h | UTC

Expert Consensus on the Management of Brain Arteriovenous Malformations – Asian Journal of Neurosurgery (free)

 


Study Shows Alarming Spike in Electric Scooter Injuries

12 Jan, 2020 | 20:49h | UTC

Electric Scooter Injuries and Hospital Admissions in the United States, 2014-2018 – JAMA Surgery (free for a limited period)

Commentaries: Urban health scare: E-scooters show alarming spike in injuries – University of California – San Francisco (free) AND Scooter-related injuries are spiking in the United States, study finds – CNN (free) AND Head Injuries Common Among Electric Scooter Riders – MedicalResearch.com (free)

 


Highlights from the Guidelines for Managing Severe Traumatic Brain Injury in Children

10 Jan, 2020 | 08:28h | UTC

Critical Update on the Third Edition of the Guidelines for Managing Severe Traumatic Brain Injury in Children – American Journal of Critical Care (free)

Original Article: New Guidelines for the Management of Pediatric Severe Traumatic Brain Injury (free guideline and news release)

 


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