Neurosurgery
AHA/ASA Guideline for the management of patients with aneurysmal subarachnoid hemorrhage
29 May, 2023 | 11:16h | UTCTop Things to Know: 2023 Aneurysmal Subarachnoid Hemorrhage Guideline – American Heart Association
Commentary on Twitter
2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association https://t.co/IHZRkTR25t@American_Heart @American_Stroke @AHAScience @BrianHoh1 @drdangayach @CPDerdeyn pic.twitter.com/I2JdXnHuXp
— Stroke AHA/ASA (@StrokeAHA_ASA) May 23, 2023
Guideline | Targeted temperature management in intracerebral, subarachnoid hemorrhage and acute ischemic stroke
29 May, 2023 | 10:48h | UTC
Guideline | Assessment and early management of head injury
23 May, 2023 | 13:11h | UTCHead injury: assessment and early management – NICE
Commentary: NICE head injury guidelines 2023: Now who do we scan? – St Emilyn’s
Neurosurgical interventions for cerebral metastases of solid tumors
11 May, 2023 | 11:48h | UTC
Review | Early switch to oral antimicrobials in brain abscess
10 May, 2023 | 15:55h | UTC
ESTES recommendation on thoracolumbar spine fractures
10 May, 2023 | 15:40h | UTC
RCT | Craniotomy and decompressive craniectomy yield comparable outcomes in acute subdural hematoma
2 May, 2023 | 13:51h | UTCDecompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: International study recommends replacing skull section after treatment for a brain bleed – University of Cambridge
Commentary on Twitter
Presented at #AANS2023: In an international trial involving 450 patients with acute subdural hematoma, craniotomy (replacing bone flap) and decompressive craniectomy (removing bone flap) yielded similar disability results at 12 months. https://t.co/KoNebwQIsi#neurosurgery pic.twitter.com/t9E9YZeHyq
— NEJM (@NEJM) April 23, 2023
M-A | Pain management interventions for the treatment of chronic low back pain
2 May, 2023 | 13:26h | UTC
M-A | Efficacy of erector spinae plane block for postoperative analgesia lumbar surgery
26 Apr, 2023 | 13:53h | UTC
M-A | Surgical versus non-surgical treatment for sciatica
25 Apr, 2023 | 14:39h | UTCEditorial: Early surgery for sciatica – The BMJ
News Release: Surgery for sciatica reduces leg pain and disability, but benefits are short-lived – University of Oxford
Commentary on Twitter
Very low to low certainty evidence suggests that discectomy was superior to non-surgical treatment or epidural steroid injections in reducing leg pain and disability in people with sciatica with a surgical indication, but the benefits reduced over timehttps://t.co/kHL2HBNscF
— The BMJ (@bmj_latest) April 19, 2023
Brief Review | Management of pituitary incidentalomas
25 Apr, 2023 | 14:14h | UTCManagement of pituitary incidentalomas – Clinical Medicine Journal
Prehospital guidelines for the management of traumatic brain injury
24 Apr, 2023 | 13:45h | UTC
RCT | Stereotactic radiosurgery vs. conventional radiotherapy for localized vertebral metastases of the spine
24 Apr, 2023 | 13:37h | UTCStereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Audio interview: Radiosurgery of Spine Metastasis—NRG/RTOG 0631 RCT Final Results – JAMA
Commentary on Twitter
Phase 3 rand trial of spinal radiosurgery vs. conventional external beam radiation therapy for pts w/spinal metastases showed radiosurgery did not significantly improve pain response at 3mo but showed feasibility that makes it widely used today. https://t.co/LvZY1nbUpS #RadOnc
— JAMA Oncology (@JAMAOnc) April 20, 2023
Cohort Study | Prehospital end-tidal CO2 levels and mortality in suspected severe traumatic brain injury patients
24 Apr, 2023 | 13:35h | UTCEditorial: Prehospital ventilation targets in severe traumatic brain injury – Intensive Care Medicine
Commentary on Twitter
Prehospital etCO2 in severe #TBI, BRAIN-PROTECT study
🚁 L-shaped association with mortality
🧠 35-45 mmHg seems reasonable target: lower ETCO2? sharp mortality ⬆️
🖇️ https://t.co/DC0DoHa00NWith editorial on MV targets & reliability of available data
🖇️ https://t.co/jVZ4zZVHxv pic.twitter.com/74vKxjyGpA— Intensive Care Medicine (@yourICM) April 20, 2023
Cohort Study | Major cardiovascular events after spontaneous intracerebral hemorrhage by hematoma location
12 Apr, 2023 | 13:13h | UTCInvited Commentary: Major Adverse Cardiovascular Events After Intracerebral Hemorrhage—It’s All About Location, Location, Location – JAMA Network Open
RCT | Drain usage may increase the length of hospital stay following lumbar arthrodesis
31 Mar, 2023 | 13:18h | UTCCommentary: Wound drains increase hospital los after lumbar surgery? – Orthopedics This Week
Expanding Organ Usage: UK study finds organs from patients with a primary brain tumor are a viable option
27 Mar, 2023 | 13:27h | UTCSummary: A national cohort study in the UK investigated the risk of cancer transmission from deceased donors with primary brain tumors to organ recipients. The study found no cases of brain tumor transmission among 778 transplants from 282 donors with primary brain tumors, including 262 from donors with high-grade tumors. Organ transplant survival was equivalent to that in matched controls, and some organs from donors with high-grade tumors were less likely to be transplanted.
The results suggest that the risk of cancer transmission in transplants from deceased donors with primary brain tumors is lower than previously thought. Furthermore, the study indicated that donors with brain tumors provided good-quality organs with favorable risk markers and excellent transplant outcomes. Some organs from donors with high-grade tumors were underutilized, indicating a possible aversion by transplant clinicians or patients to use these organs.
These findings imply that it may be possible to safely expand organ usage from donors with primary brain tumors without negatively impacting outcomes, potentially benefiting many patients waiting for a transplant. Although this might lead to a slight rise in transplant numbers in the UK, the findings may hold particular significance for nations with stricter guidelines, such as the United States. The study’s findings can help transplant clinicians discuss the risks and benefits of accepting organ offers from such donors.
Cohort Study | Functional recovery, symptoms, and quality of life 1 to 5 years after traumatic brain injury
24 Mar, 2023 | 12:52h | UTC
Review | Neuromonitoring in critically ill patients
20 Mar, 2023 | 13:18h | UTCNeuromonitoring in Critically Ill Patients – Critical Care Medicine (free for a limited period)
Related: The importance of neuromonitoring in non-brain injured patients – Critical Care
Review | Neurogenic shock: definition, identification, and management in the ED
20 Mar, 2023 | 13:09h | UTCNeurogenic Shock: Definition, Identification, and Management in the ED – emDocs
M-A | Endoscopic surgery for spontaneous supratentorial intracerebral hemorrhage
16 Mar, 2023 | 13:04h | UTC
Global validation of the AO Spine Upper Cervical Injury Classification
16 Mar, 2023 | 12:58h | UTCGlobal Validation of the AO Spine Upper Cervical Injury Classification – Spine
Consensus Recommendations | Spinal tumors
9 Mar, 2023 | 14:15h | UTC
SR | Spinal cord stimulation for low back pain provides no sustained clinical benefits compared to placebo
9 Mar, 2023 | 14:12h | UTCSummary: Spinal cord stimulation (SCS) is a surgical procedure used to treat persistent low back pain by sending electrical signals via implanted electrodes into the spinal cord. The review included 13 studies (randomized controlled trials and cross‐over trials) with 699 participants.
Most of the studies were focused on short-term effects (less than one month), but the review found it is uncertain whether spinal cord stimulation can improve outcomes in the immediate term compared with placebo. At six months, SCS probably does not improve back or leg pain, function, or quality of life compared with placebo, with moderate certainty of evidence. Adverse events were also reported, including infections, neurological damage, and lead migration requiring repeated surgery.
The review concluded that the data does not support the use of SCS to manage low back pain outside a clinical trial. Current evidence suggests SCS probably does not have sustained clinical benefits that would outweigh the costs and risks of this surgical intervention.
Article: Spinal cord stimulation for low back pain – Cochrane Library
Summary: Spinal cord stimulation for low back pain – Cochrane Library
Commentary from the author on Twitter
Our Cochrane review on spinal cord stimulators for #backpain out today.
Bottom line:
-Mod certainty evidence of no benefit vs placebo in medium term
-Uncertain if benefit on pain in immediate term
-Adverse events (infection, re-operation) commonhttps://t.co/lNJQeN96Zs— Adrian Traeger (@adrian_traeger) March 7, 2023
Cohort Study | Lifetime traumatic brain injury and cognitive domain deficits in late life
2 Mar, 2023 | 12:45h | UTCLifetime Traumatic Brain Injury and Cognitive Domain Deficits in Late Life: The PROTECT-TBI Cohort Study – Journal of Neurotrauma (link to abstract – you can try this link for full-text)
News Release: Three or more concussions linked with worse brain function in later life – University of Exeter