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Pediatrics – Gastroenterology

Pediatric acute liver failure: reexamining key clinical features, current management, and research prospects.

12 Aug, 2022 | 14:17h | UTC

Pediatric acute liver failure: Reexamining key clinical features, current management, and research prospects – Liver Transplantation

 


Severe acute hepatitis of unknown etiology in children—what is known?

2 Aug, 2022 | 12:39h | UTC

Severe acute hepatitis of unknown aetiology in children—what is known? – BMC Medicine

Related:

A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Indeterminate pediatric acute liver failure: Clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022 – UEG Journal

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Pediatric intestinal pseudo-obstruction: progress and challenges.

15 Jul, 2022 | 12:24h | UTC

Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges – Frontiers in Pediatrics

 


A case series of children with acute hepatitis and human Adenovirus infection.

14 Jul, 2022 | 12:56h | UTC

A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (free registration required)

 

Commentaries on Twitter

 


WHO Updated Report | Severe acute hepatitis of unknown etiology in children.

14 Jul, 2022 | 12:54h | UTC

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Related:

Indeterminate pediatric acute liver failure: Clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022 – UEG Journal

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Cohort Study | Prediction models for celiac disease development in children from high-risk families.

14 Jul, 2022 | 12:31h | UTC

Prediction Models for Celiac Disease Development in Children From High-Risk Families: Data From the PreventCD Cohort – Gastroenterology

 


Consensus on the management of complications of cirrhosis of the liver in pediatrics.

11 Jul, 2022 | 12:24h | UTC

Consensus on the management of complications of cirrhosis of the liver in pediatrics – Revista de Gastroenterología de México (English Edition)

 


M-A | Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrheal disease in children in low-income and middle-income settings.

6 Jul, 2022 | 11:56h | UTC

Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrhoeal disease in children in low-income and middle-income settings: a systematic review and meta-analysis – The Lancet

 

Commentary on Twitter


Position Paper | The role of surgical management in chronic pancreatitis in children.

6 Jul, 2022 | 11:37h | UTC

The Role of Surgical Management in Chronic Pancreatitis in Children: A Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee – Journal of Pediatric Gastroenterology and Nutrition

 

Commentary on Twitter


RCT | Odevixibat treatment in progressive familial intrahepatic cholestasis.

6 Jul, 2022 | 11:35h | UTC

Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial – The Lancet Gastroenterology & Hepatology

Invited Commentary: The first new drug for progressive familial intrahepatic cholestasis – The Lancet Gastroenterology & Hepatology (free registration required)

 

Commentary on Twitter


Indeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.

5 Jul, 2022 | 12:09h | UTC

Indeterminate pediatric acute liver failure: Clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022 – UEG Journal

Related:

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press


Brief Review | Sudden onset hepatitis in children.

4 Jul, 2022 | 12:41h | UTC

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)

 

Commentary on Twitter


RCT: FODMAP diet vs. medication in primary care patients with irritable bowel syndrome.

1 Jul, 2022 | 10:46h | UTC

Diet or medication in primary care patients with IBS: the DOMINO study – a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute – Gut (link to abstract – $ for full-text)

 


ESPGHAN position paper on management and follow-up of children and adolescents with coeliac disease.

29 Jun, 2022 | 11:32h | UTC

ESPGHAN position paper on management and follow-up of children and adolescents with coeliac disease – Pediatric Gastroenterology and Nutrition

 


WHO Updated Report: Severe acute hepatitis of unknown etiology in children.

28 Jun, 2022 | 11:23h | UTC

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Related:

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


ESPGHAN Position Paper: use of low-FODMAP diet in pediatric gastroenterology.

24 Jun, 2022 | 11:15h | UTC

An ESPGHAN Position Paper on the Use of Low-FODMAP Diet in Pediatric Gastroenterology – Pediatric Gastroenterology and Nutrition

 


RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.

22 Jun, 2022 | 11:12h | UTC

Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)

 

Commentary on Twitter

 


M-A: Reproducibility of food challenge to cow’s milk.

15 Jun, 2022 | 10:42h | UTC

Reproducibility of food challenge to cow’s milk: a systematic review with individual participant data meta-analysis – Journal of Allergy and Clinical Immunology

 


Position Paper: Diagnostic therapeutic care pathway for pediatric food allergies and intolerances.

14 Jun, 2022 | 11:05h | UTC

Diagnostic therapeutic care pathway for pediatric food allergies and intolerances in Italy: a joint position paper by the Italian Society for Pediatric Gastroenterology Hepatology and Nutrition (SIGENP) and the Italian Society for Pediatric Allergy and Immunology (SIAIP) – Italian Journal of Pediatrics

 


Case Series | Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit.

13 Jun, 2022 | 10:46h | UTC

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Related: Investigating acute hepatitis of unknown origin in children (several resources on the subject)

 

Commentary on Twitter

 


Consensus statements on the transition of adolescents and young adults with inflammatory bowel disease from pediatric to adult care.

8 Jun, 2022 | 11:03h | UTC

Canadian Consensus Statements on the Transition of Adolescents and Young Adults with Inflammatory Bowel Disease from Pediatric to Adult Care: A Collaborative Initiative Between the Canadian IBD Transition Network and Crohn’s and Colitis Canada – Journal of the Canadian Association of Gastroenterology

 


Consensus Statement: Diagnostic action against hypertransaminasemia in pediatrics.

6 Jun, 2022 | 11:23h | UTC

Diagnostic action against hypertransaminasemia in paediatrics: Consensus document of Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica (SEGHNP), Asociación Española de Pediatría de Atención Primaria (AEPap) and Sociedad Española de Pediatría de Atención Primaria (SEPEAP) – Anales de Pediatría (English Edition)

 


Consensus on the diagnosis and treatment of cow’s milk protein allergy.

2 Jun, 2022 | 10:56h | UTC

Consensus on the diagnosis and treatment of cow’s milk protein allergy of the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition – Revista de Gastroenterología de México (English Edition)

 


Recommendation document on rapid intravenous rehydration in acute gastroenteritis.

31 May, 2022 | 11:27h | UTC

Recommendation document on rapid intravenous rehydration in acute gastroenteritis – Anales de Pediatría (English Edition)

 


Investigating acute hepatitis of unknown origin in children.

30 May, 2022 | 11:39h | UTC

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

Related:

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 

Commentary on Twitter

 


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