Pediatrics – Gastroenterology
ESPGHAN Position Paper: use of low-FODMAP diet in pediatric gastroenterology.
24 Jun, 2022 | 11:15h | UTC
RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.
22 Jun, 2022 | 11:12h | UTCMultispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)
Commentary on Twitter
Study found administration of a multispecies #probiotic to children had no significant effect on the risk of antibiotic-associated diarrhea caused by #Cdifficile or of unknown etiology, but reduced the overall risk of diarrhea regardless of the etiology. https://t.co/Mdq3tl8csb
— JAMA Pediatrics (@JAMAPediatrics) June 21, 2022
M-A: Reproducibility of food challenge to cow’s milk.
15 Jun, 2022 | 10:42h | UTC
Position Paper: Diagnostic therapeutic care pathway for pediatric food allergies and intolerances.
14 Jun, 2022 | 11:05h | UTC
Case Series | Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit.
13 Jun, 2022 | 10:46h | UTCOutbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Related: Investigating acute hepatitis of unknown origin in children (several resources on the subject)
Commentary on Twitter
Outbreak of non-A-E hepatitis in children, 🇬🇧 data. Good outcomes if ALF by dedicated liver #ICU with early referral to Tx centres, recognizing neuro-deterioration, high-volume #ECLS, close neuromonitoring/protection & support by hepatology/Tx physicians
📎https://t.co/GYAMaZbVGD pic.twitter.com/GA58vJWQIz— Intensive Care Medicine (@yourICM) June 10, 2022
Consensus statements on the transition of adolescents and young adults with inflammatory bowel disease from pediatric to adult care.
8 Jun, 2022 | 11:03h | UTC
Consensus Statement: Diagnostic action against hypertransaminasemia in pediatrics.
6 Jun, 2022 | 11:23h | UTC
Consensus on the diagnosis and treatment of cow’s milk protein allergy.
2 Jun, 2022 | 10:56h | UTC
Recommendation document on rapid intravenous rehydration in acute gastroenteritis.
31 May, 2022 | 11:27h | UTC
Investigating acute hepatitis of unknown origin in children.
30 May, 2022 | 11:39h | UTCInvestigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
Related:
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
Unexplained, severe acute hepatitis has been increasingly reported in children. Adenovirus has been detected in some (but not all) cases & is being investigated as 1 of many potential causes. @andreaprinzi discusses the ongoing epidemiologic investigation: https://t.co/P6EPdT8sOA
— ASM (@ASMicrobiology) May 27, 2022
Systematic Review: Airway complications resulting from pediatric esophageal button battery impaction.
27 May, 2022 | 11:49h | UTCAirway Complications Resulting From Pediatric Esophageal Button Battery Impaction: A Systematic Review – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Invited Commentary: Pediatric Button Battery Injuries—Current State and What’s Next? – JAMA Otolaryngology-Head & Neck Surgery
Joint consensus guidelines on the diagnosis and management of eosinophilic esophagitis in children and adults.
25 May, 2022 | 11:32h | UTC
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both?
23 May, 2022 | 01:48h | UTCWhat’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Related:
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Hypotheses | Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens.
16 May, 2022 | 02:22h | UTCRelated:
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A solid hypothesis for the basis of the mysterious, severe acute hepatitis in children: superantigen formation from prior Covid viral reservoir in the GI tract with superimposed adenovirus infection https://t.co/1eehyQmlhi @LancetGastroHep pic.twitter.com/UqCAh3igMH
— Eric Topol (@EricTopol) May 14, 2022
Explaining the unexplained hepatitis in children.
13 May, 2022 | 11:39h | UTCExplaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Related:
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Epidemiological update: Hepatitis of unknown etiology in children.
12 May, 2022 | 10:12h | UTCRelated:
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter (thread – click for more)
Update: #Hepatitis of unknown aetiology in children – 11 May 2022
Approximately 106 cases have been identified in 14 EU/EEA countries and 450 cases are reported worldwide.
The cause of the disease is still under investigation.
Read more: https://t.co/B0lLm7I0dV— ECDC Outbreaks (@ECDC_Outbreaks) May 11, 2022
Technical briefing 2: Investigation into acute hepatitis of unknown etiology in children in England.
9 May, 2022 | 02:18h | UTCRelated: With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids (several updates on the subject)
Summary on Twitter (thread – click for more)
NEW: @UKHSA Technical Briefing 2 on Paediatric acute hepatitis in England
A 🧵 ⤵️https://t.co/E9MvVTK505 pic.twitter.com/YZCHdCdt4U
— 🇺🇦 Meaghan Kall (@kallmemeg) May 6, 2022
Podcast: Appendicitis Pearls.
9 May, 2022 | 01:15h | UTC#49: Appendicitis – Tips and Tricks For When It’s the Appendix – The Cribsiders
With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids.
5 May, 2022 | 10:59h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
CDC Report: Acute hepatitis and adenovirus infection among children.
2 May, 2022 | 00:46h | UTCCommentaries:
CDC releases new clinical details in cases of unusual hepatitis in children – CNN
CDC report finds no Covid link in children’s hepatitis cases in Alabama – NBC News
Related:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentaries on Twitter
Report from Alabama of acute hepatitis & adenovirus infection in young kids, Oct 21-Feb 22. 9 cases, all had adenovirus, 5/5 tested +ve for Adenovirus type 41. No epi links found. All under 6 yrs of age, immunocompetent, & no significant comorbidities. https://t.co/DcgcfN3KHo
— Andrew Lee (@andrewleedr) April 29, 2022
New report from @CDCMMWR on the 9 episodes of severe acute hepatitis in children from Alabama
All 9 positive for Adenovirus on whole blood PCR (all 5 samples sequences were type 41)
None PCR positive for #SARSCoV2
HT @tonisoriano66 https://t.co/h9LmHeVHEf
— Alasdair Munro (@apsmunro) April 29, 2022
ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.
2 May, 2022 | 00:44h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.
29 Apr, 2022 | 11:07h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Report: Investigation into acute hepatitis of unknown etiology in children in England.
27 Apr, 2022 | 08:08h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A comprehensive technical report is now available on the cases of hepatitis in young children
Leading hypothesis still Adenovirus, often only positive in blood
Of note, in cases where transplant was required virus levels were 12x higher than other caseshttps://t.co/VMk1qoIyNb
— Alasdair Munro (@apsmunro) April 26, 2022
A therapeutic guide on pediatric irritable bowel syndrome and functional abdominal pain-not otherwise specified.
26 Apr, 2022 | 07:58h | UTC
WHO: Multi-country – acute, severe hepatitis of unknown origin in children.
25 Apr, 2022 | 01:13h | UTCMulti-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
Commentaries:
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
At least one child has died from mystery strain of severe hepatitis, WHO confirms – The Guardian
Related:
CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention AND Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press