Oncology – Gynecologic
M-A of randomized trials | Hyperthermic intraperitoneal chemotherapy (HIPEC) for the management of primary advanced and recurrent ovarian cancer.
20 Sep, 2022 | 13:23h | UTCRelated:
Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer – New England Journal of Medicine
Systematic Review | Debulking hysterectomy followed by chemoradiotherapy vs. chemoradiotherapy alone for women with locally advanced cancer of the cervix – not enough evidence to guide recommendations.
19 Sep, 2022 | 12:39h | UTC
Systematic Review | Ultra‐radical (extensive) surgery vs. standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer.
13 Sep, 2022 | 12:56h | UTCRelated Study: Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer – New England Journal of Medicine
Screening for high-risk human papillomavirus using passive, self-collected menstrual blood.
11 Sep, 2022 | 22:41h | UTCCommentary: Pap smears, be gone? Using menstrual blood to detect HPV – Stanford Medicine
Commentary on Twitter
FREE: Screening for High-Risk Human Papillomavirus Using Passive, Self-Collected Menstrual Blood #obgyn #HPV #GYN https://t.co/zLno2ab605 pic.twitter.com/mfPGjlTLdD
— The Green Journal (@greenjrnl) September 1, 2022
RCT | Overall survival with maintenance Olaparib at a 7-year follow-up in patients with newly diagnosed advanced ovarian cancer and a BRCA mutation.
11 Sep, 2022 | 22:21h | UTC
A simple cervicovaginal epigenetic test for screening and rapid triage of women with suspected endometrial cancer: validation in several cohort and case/control sets.
29 Aug, 2022 | 11:58h | UTC
Commentary on Twitter
Pleased to share our work out today in J Clin Oncol "A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer …" #FORECEE #CCBIO #H2020 @eveappeal @Gynkreft @medofak_uib @haukeland_no
#screening https://t.co/Av53WSWqoQ pic.twitter.com/dL4j7nW7vt— Line Bjørge (@DrLB) August 24, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
RCT | HPV self-sampling among long-term non-attenders to cervical cancer screening.
26 Aug, 2022 | 13:27h | UTC
Commentary on Twitter
Pragmatic randomised controlled trial of 3 different HPV screening approaches suggests that opt-in and particularlly send-to-all self-sampling increased participation among long-term, higher-risk non-attenders: https://t.co/hBouqoBMnU #GynCSM #hsronc
— NatureRevClinOncol (@NatRevClinOncol) August 25, 2022
Endocervical sampling in women with suspected cervical neoplasia: a systematic review and meta-analysis of diagnostic test accuracy studies.
26 Aug, 2022 | 13:18h | UTC
Systematic Review | Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer.
26 Aug, 2022 | 13:11h | UTC
Observational study suggests frequent aspirin use may reduce the risk of ovarian cancer.
25 Aug, 2022 | 11:49h | UTCModification of the Association Between Frequent Aspirin Use and Ovarian Cancer Risk: A Meta-Analysis Using Individual-Level Data From Two Ovarian Cancer Consortia – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries:
Frequent Aspirin Use Tied to Lower Ovarian Cancer Risk – HealthDay
Commentary on Twitter
💊 Frequent aspirin use ⬇️ #OvarianCancer risk among women with other risk factors for ovarian cancer
Read more in #JCO: https://t.co/QV4bK0lB5M #prevention #gyncsm #ovca @LaurenMHurwitz @b_trabert pic.twitter.com/xvU1yb60mi
— Journal of Clinical Oncology (@JCO_ASCO) August 18, 2022
Long-term follow up of a RCT | Precancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine.
24 Aug, 2022 | 13:53h | UTCPrecancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine: an analysis of the long-term follow-up study from the randomised Costa Rica HPV Vaccine Trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Virological replacement & clinical unmasking are two phenomena of interest following #HPVvaccination. We show that clinical unmasking might attenuate long-term reductions in cervical precancer following successful implementation of HPV vax programs in highly screened populations https://t.co/Z7dGQNG1kG
— Monica Sierra (@MonicaSSierra) June 14, 2022
Systematic Review | Menopausal status, ultrasound and biomarker tests in combination for the diagnosis of ovarian cancer in symptomatic women.
17 Aug, 2022 | 14:12h | UTC
M-A | Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment.
5 Aug, 2022 | 14:43h | UTCNews Release: HPV vaccination alongside surgery for cervical lesions may reduce risk of further disease – BMJ Newsroom
Systematic Review | Endometrial cancer and BRCA mutations.
5 Aug, 2022 | 14:09h | UTCEndometrial Cancer and BRCA Mutations: A Systematic Review – Journal of Clinical Medicine
Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease.
1 Aug, 2022 | 12:09h | UTC
RCT | Effectiveness of intensive vs. minimalist follow-up regimen on survival in patients with endometrial cancer.
25 Jul, 2022 | 12:42h | UTCEffectiveness of Intensive Versus Minimalist Follow-Up Regimen on Survival in Patients With Endometrial Cancer (TOTEM Study): A Randomized, Pragmatic, Parallel Group, Multicenter Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Network M-A | Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer.
18 Jul, 2022 | 11:27h | UTC
Commentary on Twitter
Online first: Comparative effectiveness and risk of #preterm #birth of local #treatments for #cervicalintraepithelialneoplasia and stage IA1 #cervicalcancer: a systematic review and network meta-analysis https://t.co/APwtqyXJKO pic.twitter.com/GYuoroxRmw
— The Lancet Oncology (@TheLancetOncol) July 12, 2022
Female erectile tissues and sexual dysfunction after pelvic radiotherapy: a scoping review.
13 Jul, 2022 | 11:23h | UTC
RCT | Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal cancer treatment.
12 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
Updated results from the phase III ICON8 trial in 1,566 pts with newly diagnosed stage IC–IV epithelial ovarian, peritoneal or fallopian tube carcinoma reveal no statistically significant difference in OS with 3-weekly vs weekly carboplatin & paclitaxel: https://t.co/czgH7uGxjt
— NatureRevClinOncol (@NatRevClinOncol) June 15, 2022
RCT: Effect of Apatinib plus Pegylated Liposomal Doxorubicin vs. Pegylated Liposomal Doxorubicin alone on platinum-resistant recurrent ovarian cancer.
1 Jul, 2022 | 10:37h | UTCSee also: Visual Abstract
RCT: Maintenance Taxanes vs. surveillance in women with advanced ovarian/tubal/peritoneal cancer.
29 Jun, 2022 | 10:57h | UTCPhase III Randomized Trial of Maintenance Taxanes Versus Surveillance in Women With Advanced Ovarian/Tubal/Peritoneal Cancer: A Gynecologic Oncology Group 0212:NRG Oncology Study – Journal of Clinical Oncology (link to abstract – $ for full-text)
Consensus Statement: First-line PARP inhibitor maintenance for advanced, high-grade serous and endometrioid tubal, ovarian, and primary peritoneal cancers.
27 Jun, 2022 | 11:34h | UTC
International consensus statements on pre-invasive vulvar lesions.
23 Jun, 2022 | 10:21h | UTCNews Release: New Guidelines Address Treatment of Pre-Invasive Lesions of the Vulva – Wolters Kluwer Health: Lippincott
ESMO Guideline: Diagnosis, treatment, and follow-up of endometrial cancer.
13 Jun, 2022 | 08:08h | UTC
Screening every five years safe for women who test negative for HPV, study confirms.
9 Jun, 2022 | 11:26h | UTCNews Release: Screening every five years safe for women who test negative for HPV, study confirms – King’s College London
Editorial: HPV screening for cervical cancer is reaching maturity – The BMJ
Related WHO Guidance:
News release: New recommendations for screening and treatment to prevent cervical cancer – World Health Organization
Related USPSTF Guidance: Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement – JAMA