Transplantation (all articles)
Cardiac xenotransplantation: challenges, evolution, and advances.
20 Jun, 2022 | 00:58h | UTCCommentary: Many Hurdles to Clear Before Cardiac Xenotransplantation Takes Off – TCTMD
Related:
In 1st, US surgeons transplant pig heart into human patient – Associated Press
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight – STAT
Review: Dyspnea and cough in a lung transplant recipient.
7 Jun, 2022 | 11:16h | UTCDyspnea and cough in a lung transplant recipient – Cleveland Clinic Journal of Medicine
RCT: Effect of perioperative dexmedetomidine on delayed graft function following a donation-after-cardiac-death kidney transplant.
7 Jun, 2022 | 10:55h | UTC
Commentary on Twitter
In this RCT, 24-hour dexmedetomidine infusion, started immediately after induction of & in addition to standard anesthesia, reduced the incidence of delayed graft function vs placebo, following a donation-after-cardiac-death kidney transplantation. https://t.co/cmX1IEZdVX
— JAMA Network Open (@JAMANetworkOpen) June 3, 2022
Exploratory RCT suggests Cardiovascular Magnetic Resonance accurately diagnoses cardiac allograft rejection in the first year after transplantation.
6 Jun, 2022 | 10:56h | UTCNews Release: Virtual biopsy set to transform heart transplant care – Victor Chang Cardiac Research Institute
Commentary on Twitter
#OriginalResearch: In this #RCT, #CMR-based surveillance reliably graded cardiac allograft rejection compared to a biopsy-based strategy @vass_vassiliou #AHAJournals https://t.co/0kbpeXUtu1 pic.twitter.com/FwDGdJldHK
— Circulation (@CircAHA) June 2, 2022
M-A: Risks for donors associated with living kidney donation.
31 May, 2022 | 11:23h | UTCRisks for donors associated with living kidney donation: meta-analysis – British Journal of Surgery
Commentary from the author on Twitter (thread – click for more)
#DiversityAndInclusion 🚺🚹when counseling #Living #Kidney #Donors: our meta-analysis on the #risks stratified according to donor demographic characteristics has just been published @BJSurgery 🔗https://t.co/LtXpPeykiM @MichaelNozdrin @lisetpengel @transplantev 🧵1/7 pic.twitter.com/WszUiTAd1Q
— Maria Irene Bellini MD, PhD, FEBS (@mirenebellini1) May 26, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
The role of T-tubes and abdominal drains on short-term outcomes in liver transplantation – A systematic review of the literature and expert panel recommendations.
26 May, 2022 | 10:04h | UTC
Results of two cases of pig-to-human kidney xenotransplantation.
19 May, 2022 | 11:11h | UTCResults of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Genetically modified pig kidney xenografts were transplanted into two brain-dead human recipients. The xenografts functioned immediately, showed no evidence of acute rejection over a period of 54 hours. https://t.co/gWlpX1dCTC pic.twitter.com/Zp5XdA4QH5
— NEJM (@NEJM) May 18, 2022
Cohort Study: Spectrum of nonkeratinocyte skin cancer risk among solid organ transplant recipients.
5 May, 2022 | 09:37h | UTCSpectrum of Nonkeratinocyte Skin Cancer Risk Among Solid Organ Transplant Recipients in the US – JAMA Dermatology (link to abstract – $ for full-text)
Author Interview: Nonkeratinocyte Skin Cancer Risk Among Solid Organ Transplant Recipients
Commentary on Twitter
This cohort study found elevated incidence for common and rare skin #cancer in solid organ #transplant recipients. Long-term immunosuppression and UV radiation are important risk factors. Treatment with mTOR inhibitors may reduce #melanoma risk. https://t.co/V6Wbbhtyeq
— JAMA Dermatology (@JAMADerm) March 9, 2022
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.
29 Apr, 2022 | 10:51h | UTC
Commentary on Twitter
🆕💥Review Article @ASHE_Journal
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them #IDTwitter #medtwitter #TwitteRx #MedEd https://t.co/ToPLQXtC4r pic.twitter.com/pZQWWb3ZSx— Antibiotic Steward Bassam Ghanem🆔🔥 (@ABsteward) April 28, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
Pre-transplant EASIX (endothelial activation and stress index) may predict the hazard of sepsis after allogeneic stem cell transplantation.
19 Apr, 2022 | 02:04h | UTCPre-transplant EASIX and sepsis after allogeneic stem cell transplantation – Intensive Care Medicine
Commentary on Twitter
🧪 Endothelial complications major causes of mortality post alloSCT. Pre Tx Endothelial Activation & Stress IndeX EASIX (basic lab data characterizing Tx-associated thrombotic microangiopathy) powerful marker of #sepsis, dysfunctional endothelial response.https://t.co/FRGUGT8L78 pic.twitter.com/VF2wTLCHaM
— Intensive Care Medicine (@yourICM) April 18, 2022
Cohort Study: Recipient and donor outcomes after living-donor liver transplant for unresectable colorectal liver metastases.
6 Apr, 2022 | 10:23h | UTCCommentaries:
Living-Donor Liver Transplant Promising for CRC With Liver Mets – HealthDay
Commentary on Twitter
Study suggests living-donor liver transplant is a promising option for meticulously selected patients with unresectable colorectal cancer liver metastases. https://t.co/p6Jbzb73DL
— JAMA Surgery (@JAMASurgery) March 30, 2022
Opinion: Moving xenotransplantation research into human trials will require adjusting our expectations, researchers say.
6 Apr, 2022 | 09:59h | UTCRelated:
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight.
In 1st, US surgeons transplant pig heart into human patient.
M-A: The impact of cold ischemia time on outcomes of living donor kidney transplantation.
24 Mar, 2022 | 08:33h | UTC
Editorial: Pig-to-human transplants take a leap toward reality.
22 Mar, 2022 | 08:31h | UTCPig-to-human transplants take a leap toward reality – Nature Medicine
Retrospective Cohort Study: Association of donor brain death due to stroke with prognosis after heart transplantation.
17 Mar, 2022 | 08:33h | UTCAssociation of Donor Brain Death Due to Stroke With Prognosis After Heart Transplantation – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Young Stroke Victims’ Hearts Might Not Be as Good for Transplantation – MedPage Today
Commentary on Twitter
🔑 Takeaway: #Stroke as the cause of donor brain death compared to all other causes of brain death was not associated w/ increased mortality or allograft failure in heart transplant recipients. Read more: https://t.co/NynBVsQSqh #cvSurg #cvHCM @MartyTamMD
— American College of Cardiology (@ACCinTouch) March 16, 2022
Comparing bowel lengthening procedures: which, when, and why?
11 Mar, 2022 | 09:33h | UTC
M-A: Efficacy of covid-19 vaccines in immunocompromised patients.
4 Mar, 2022 | 10:01h | UTCNews Release: Study suggests additional covid-19 vaccine doses for immunocompromised patients – BMJ Newsroom
Related: Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review.
Commentary on Twitter
NEW RESEARCH: Additional doses of covid-19 vaccine are recommended for immunocompromised patients, especially for organ transplant recipients who are least able to make antibodies to fight off coronavirus, suggests new research https://t.co/l2IWfSb0zd @sundar__raghav
— The BMJ (@bmj_latest) March 3, 2022
M-A: Survival for waitlisted kidney failure patients receiving transplantation vs. remaining on waiting list.
2 Mar, 2022 | 08:46h | UTC
Review: Cardiac considerations in liver transplantation.
18 Feb, 2022 | 08:26h | UTCCardiac considerations in liver transplantation – Cleveland Clinic Journal of Medicine
Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review.
16 Feb, 2022 | 10:13h | UTC
Commentary on Twitter
A review of the 23 studies of Covid vaccination for immunocompromised people indicates the level of responders varies with conditions. Even additional doses may not provide sufficient protection for some, requiring additional measureshttps://t.co/BjaKrJUAbO @LancetGH pic.twitter.com/EYVWAX23Ig
— Eric Topol (@EricTopol) February 15, 2022
In a series of simultaneous pancreas and kidney transplantation cases, long-term data demonstrated that patient and graft survival were equivalent for conventional donation after circulatory death (DCD) vs. donation after brainstem death. The utilization of DCD pancreases may expand the donor pool with comparable results to DBD transplantation.
7 Feb, 2022 | 08:24h | UTC
Review: Post-transplant cardiovascular disease.
7 Feb, 2022 | 08:20h | UTCPost-Transplant Cardiovascular Disease – Clinical Journal of the American Society of Nephrology
Thinking outside the box: novel kidney protective strategies in kidney transplantation.
7 Feb, 2022 | 08:16h | UTC
Review: Advance care planning and goals of care discussions in advanced liver disease.
2 Feb, 2022 | 08:17h | UTC
RCT: Impact of portable normothermic blood-based machine perfusion on outcomes of liver transplant.
1 Feb, 2022 | 08:58h | UTCCommentaries:
Normothermic Machine Perfusion Improves Outcomes in Liver Transplant Recipients – Physician’s Weekly
Machine Perfusion Cuts Early Graft Dysfunction in Liver Transplantation – MedPage Today (free registration required)
Related:
RCT: Hypothermic machine perfusion in liver transplantation
Transplantation of Discarded Livers Following Viability Testing with Normothermic Machine Perfusion
Commentaries on Twitter
Study found portable normothermic oxygenated machine perfusion of donor liver grafts resulted in improved outcomes of liver transplantation and in more livers being transplanted. https://t.co/PZzvFriJvB pic.twitter.com/2icSfxoLDF
— JAMA Surgery (@JAMASurgery) January 5, 2022
Study found portable normothermic oxygenated machine perfusion of donor liver grafts resulted in improved outcomes of liver transplantation and in more livers being transplanted. https://t.co/TKEsTf8Htu pic.twitter.com/tg2xDGDyOS
— JAMA Surgery (@JAMASurgery) January 5, 2022