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Transplantation (all articles)

Consensus Paper | Organ donation in the surgical ICU

1 Jun, 2023 | 12:12h | UTC

Organ donation in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document – Trauma Surgery & Acute Care Open

 


ISHLT Guideline | Mechanical circulatory support

29 May, 2023 | 10:40h | UTC

The 2023 International Society for Heart and Lung Transplantation Guidelines for Mechanical Circulatory Support: A 10- Year Update – The Journal of Heart and Lung Transplantation

 


ISHLT Guidelines for the care of heart transplant recipients

3 May, 2023 | 15:09h | UTC

The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients – The Journal of Heart and Lung Transplantation

 


Extracorporeal CPR dissemination and integration with organ preservation in the USA: ethical and logistical considerations

28 Apr, 2023 | 12:47h | UTC

Extracorporeal cardiopulmonary resuscitation dissemination and integration with organ preservation in the USA: ethical and logistical considerations – Critical Care

 


Perspective | Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms

25 Apr, 2023 | 14:37h | UTC

Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms – Intensive Care Medicine

 

Commentary on Twitter

 


Cold static preservation at 10°C shows promising results for safely extending lung transplantation timeframes

24 Apr, 2023 | 13:38h | UTC

Extension of Cold Static Donor Lung Preservation at 10°C – NEJM Evidence

 

Commentary on Twitter

 


Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU

17 Apr, 2023 | 13:19h | UTC

Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Neurology, Peri-Transplant Medicine, Infectious Disease, and Gastroenterology Considerations – Critical Care Medicine (free for a limited period)

Executive Summary: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Neurology, Peri-Transplant Medicine, Infectious Disease, and Gastroenterology Considerations – Critical Care Medicine (free for a limited period)

 


Overcoming size disparity in liver transplant access: prioritizing smaller donors for smaller candidates

3 Apr, 2023 | 13:41h | UTC

Association of Body Surface Area With Access to Deceased Donor Liver Transplant and Novel Allocation Policies – JAMA Surgery (free for a limited period)

Invited Commentary: Addressing Size-Based Disparities in Liver Transplant – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

 


Expanding Organ Usage: UK study finds organs from patients with a primary brain tumor are a viable option

27 Mar, 2023 | 13:27h | UTC

Summary: A national cohort study in the UK investigated the risk of cancer transmission from deceased donors with primary brain tumors to organ recipients. The study found no cases of brain tumor transmission among 778 transplants from 282 donors with primary brain tumors, including 262 from donors with high-grade tumors. Organ transplant survival was equivalent to that in matched controls, and some organs from donors with high-grade tumors were less likely to be transplanted.

The results suggest that the risk of cancer transmission in transplants from deceased donors with primary brain tumors is lower than previously thought. Furthermore, the study indicated that donors with brain tumors provided good-quality organs with favorable risk markers and excellent transplant outcomes. Some organs from donors with high-grade tumors were underutilized, indicating a possible aversion by transplant clinicians or patients to use these organs.

These findings imply that it may be possible to safely expand organ usage from donors with primary brain tumors without negatively impacting outcomes, potentially benefiting many patients waiting for a transplant. Although this might lead to a slight rise in transplant numbers in the UK, the findings may hold particular significance for nations with stricter guidelines, such as the United States. The study’s findings can help transplant clinicians discuss the risks and benefits of accepting organ offers from such donors.

Article: Organ Transplants From Deceased Donors With Primary Brain Tumors and Risk of Cancer Transmission – JAMA Surgery

 


Review | Lung transplantation for COPD/pulmonary emphysema

27 Mar, 2023 | 12:58h | UTC

Lung transplantation for COPD/pulmonary emphysema – European Respiratory Review

 


ISCCM Position Statement | Recommendations for evaluation and selection of deceased organ donor

13 Mar, 2023 | 14:50h | UTC

Recommendations for Evaluation and Selection of Deceased Organ Donor: Position Statement of ISCCM – Indian Journal of Critical Care Medicine

 


DNA sequencing may identify an increased risk of relapse in adults with AML prior to hematopoietic cell transplantation

13 Mar, 2023 | 14:47h | UTC

DNA Sequencing to Detect Residual Disease in Adults With Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant – JAMA (free for a limited period)

News Release: Blood test identifies acute myeloid leukemia patients at greater risk for relapse after bone marrow transplant – National Institutes of Health

Commentary: Blood Test May Identify Patients With AML at Greater Risk of Relapse After Bone Marrow Transplant – The ASCO Post

 

Commentary on Twitter

 


Registry of the international society of uterus transplantation: first report

24 Feb, 2023 | 13:29h | UTC

Registry of the International Society of Uterus Transplantation: First Report – Transplantation

 


Current status of liver transplantation for non-B non-C liver cirrhosis and hepatocellular carcinoma

17 Feb, 2023 | 12:36h | UTC

Current status of liver transplantation for non-B non-C liver cirrhosis and hepatocellular carcinoma – Annals of Gastroenterological Surgery

 


Review | Management of adult patients with hematological malignancies in critical care

10 Feb, 2023 | 13:45h | UTC

Management of adult patients with haematological malignancies in critical care – Anaesthesia

 


RCT | Machine perfusion is superior to therapeutic hypothermia for reducing delayed graft function after kidney transplantation

6 Feb, 2023 | 13:28h | UTC

Hypothermia or Machine Perfusion in Kidney Donors – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Machine Perfusion of Kidneys Protects Against Delayed Graft Function – HealthDay

 

Commentary with video on Twitter

 


Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment

3 Feb, 2023 | 14:01h | UTC

Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment – BMJ Open Gastroenterology

 


Cohort Study | Risk of malignant neoplasms of the gastrointestinal tract after blood or marrow transplant

30 Jan, 2023 | 00:23h | UTC

Malignant Neoplasms of the Gastrointestinal Tract After Blood or Marrow Transplant – JAMA Oncology (link to abstract – $ for full-text)

Commentary: Risk of Subsequent Gastrointestinal Tract Malignancies After Blood or Marrow Transplantation – The ASCO Post

 

Commentary on Twitter

 


RCT | Sodium bicarbonate over 2 years was not beneficial for kidney transplant recipients with metabolic acidosis

27 Jan, 2023 | 12:23h | UTC

Sodium bicarbonate for kidney transplant recipients with metabolic acidosis in Switzerland: a multicentre, randomised, single-blind, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 


ASCO Guideline | Management of fever and neutropenia in pediatric patients with cancer and hematopoietic cell transplantation recipients

24 Jan, 2023 | 14:28h | UTC

Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update – Journal of Clinical Oncology

 


Guidelines | Enhanced recovery after surgery recommendations for renal transplantation

20 Jan, 2023 | 14:51h | UTC

Enhanced recovery after surgery recommendations for renal transplantation: guidelines – British Journal of Surgery

Related:

Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

Top 100 Most-Cited Articles on Enhanced Recovery After Surgery: A Bibliometric Analysis and Visualized Study – Frontiers in Surgery

 

Commentary on Twitter

 


An investigational T-cell therapy shows promise against six viral infections common after stem cell transplants

13 Jan, 2023 | 13:10h | UTC

News Release: An investigational T-cell therapy shows promise against six viral infections common after stem cell transplants – American Association for Cancer Research

Original Article: Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting – Clinical Cancer Research

Commentary: Study Finds Posoleucel Demonstrated Antiviral Efficacy and Safety Against Viral Infections Following Allogeneic Stem Cell Transplantation – The ASCO Post

 


Consensus Document | The use of mechanical circulatory support in lung transplantation

11 Jan, 2023 | 14:18h | UTC

The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation – The Journal of Thoracic and Cardiovascular Surgery

 

Commentary on Twitter

 


Recommendations for living donor kidney transplantation

10 Jan, 2023 | 14:39h | UTC

Recommendations for living donor kidney transplantation – Nefrología

 


Guidance on developing and/or expanding pediatric solid organ transplantation programs in low- and middle-income countries.

6 Dec, 2022 | 13:47h | UTC

International pediatric transplant association (IPTA) guidance on developing and/or expanding pediatric solid organ transplantation programs in low- and middle-income countries – Pediatric Transplantation

 


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