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Gastroenterology

Systematic Review: Antibiotics for uncomplicated diverticulitis.

27 Jun, 2022 | 11:56h | UTC

Antibiotics for uncomplicated diverticulitis – Cochrane Library

Summary: Antibiotics for uncomplicated diverticulitis – Cochrane Library

Related:

Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)

The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly – World Journal of Emergency Surgery

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

Elective surgical management of diverticulitis – Current Problems in Surgery

Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality

2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting – World Journal of Emergency Surgery

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis – Diseases of the Colon & Rectum

 

Commentary on Twitter

 


Phase 2 single-arm study: Fazirsiran for liver disease associated with Alpha1-Antitrypsin deficiency.

27 Jun, 2022 | 11:19h | UTC

Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

27 Jun, 2022 | 11:17h | UTC

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Gastroenterology & Hepatology

Commentary: Chronic Hepatitis B Infections Decreasing in Recent Years – HCP Live

 

Commentary on Twitter

 


M-A: Relationship between serum lipid level and colorectal cancer.

27 Jun, 2022 | 11:01h | UTC

Relationship between serum lipid level and colorectal cancer: a systemic review and meta-analysis – BMJ Open

 


ESPGHAN Position Paper: use of low-FODMAP diet in pediatric gastroenterology.

24 Jun, 2022 | 11:15h | UTC

An ESPGHAN Position Paper on the Use of Low-FODMAP Diet in Pediatric Gastroenterology – Pediatric Gastroenterology and Nutrition

 


Dysplastic recurrence after successful treatment for early Barrett’s neoplasia: development and validation of a prediction model.

24 Jun, 2022 | 11:07h | UTC

Dysplastic Recurrence After Successful Treatment for Early Barrett’s Neoplasia: Development and Validation of a Prediction Model – Gastroenterology

 


Consensus report on anatomy, pathophysiology and clinical significance of the gastro-esophageal junction.

23 Jun, 2022 | 10:26h | UTC

Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction – Gut

 


AGA Guidelines on the pharmacological management of irritable bowel syndrome.

23 Jun, 2022 | 10:24h | UTC

Part 1: Patients with diarrhea: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea – Gastroenterology

Part 2: Patients with constipation: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation – Gastroenterology

Commentary: AGA issues guidance on drug treatment for patients with IBS – ACP Gastroenterology

 

Commentary on Twitter

 


RCTs: Risankizumab as induction therapy for Crohn’s disease.

23 Jun, 2022 | 10:02h | UTC

Risankizumab as induction therapy for Crohn’s disease: results from the phase 3 ADVANCE and MOTIVATE induction trials – The Lancet (link to abstract – $ for full-text)

Related: Risankizumab as maintenance therapy for moderately to severely active Crohn’s disease: results from the multicentre, randomised, double-blind, placebo-controlled, withdrawal phase 3 FORTIFY maintenance trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Guideline review: EASL clinical practice guidelines: drug-induced liver injury.

22 Jun, 2022 | 11:27h | UTC

Guideline review: EASL clinical practice guidelines: drug-induced liver injury (DILI) – Frontline Gastroenterology

Original Article: EASL Clinical Practice Guidelines: Drug-induced liver injury – Journal of Hepatology

 


RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.

22 Jun, 2022 | 11:12h | UTC

Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)

 

Commentary on Twitter

 


Cohort Study: Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes.

20 Jun, 2022 | 10:36h | UTC

Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes: A prospective cohort study in the UK Biobank – eClinicalMedicine

 

Commentary on Twitter

Under a CC BY-NC-ND 4.0 license

 


RCT: Immune enhancement with Thymosin alpha 1 does not improve outcomes in patients with predicted severe acute necrotizing pancreatitis.

20 Jun, 2022 | 01:11h | UTC

Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial – Intensive Care Medicine (if the link is paywalled, try this one)

 


Consensus Recommendations: Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults.

15 Jun, 2022 | 10:58h | UTC

Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults: the Paris consensus – Gut

 


RCT: Discontinuation of Infliximab therapy in patients with Crohn’s disease.

15 Jun, 2022 | 10:54h | UTC

Discontinuation of Infliximab Therapy in Patients with Crohn’s Disease – NEJM Evidence

 


RCT: Vonoprazan triple and dual therapy for Helicobacter pylori infection.

15 Jun, 2022 | 10:41h | UTC

Vonoprazan Triple and Dual Therapy for Helicobacter pylori Infection in the US and Europe: Randomized Clinical Trial – Gastroenterology (link to abstract – $ for full-text)

 


Encephalopathy in cirrhosis: prevention and management.

15 Jun, 2022 | 10:39h | UTC

Encephalopathy in Cirrhosis: Prevention and Management – Journal of Clinical and Experimental Hepatology

 


Review: Portal vein thrombosis in cirrhosis.

15 Jun, 2022 | 10:38h | UTC

Portal Vein Thrombosis in Cirrhosis – Journal of Clinical and Experimental Hepatology

 


Review: Value of liver function tests in cirrhosis.

15 Jun, 2022 | 10:35h | UTC

Value of Liver Function Tests in Cirrhosis – Journal of Clinical and Experimental Hepatology

 


Guideline: Functional bowel disorders with diarrhea.

14 Jun, 2022 | 11:20h | UTC

Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility – UEG Journal

 


Position Paper: Diagnostic therapeutic care pathway for pediatric food allergies and intolerances.

14 Jun, 2022 | 11:05h | UTC

Diagnostic therapeutic care pathway for pediatric food allergies and intolerances in Italy: a joint position paper by the Italian Society for Pediatric Gastroenterology Hepatology and Nutrition (SIGENP) and the Italian Society for Pediatric Allergy and Immunology (SIAIP) – Italian Journal of Pediatrics

 


ASGE guideline on screening for pancreatic cancer in individuals with genetic susceptibility.

14 Jun, 2022 | 10:59h | UTC

ASGE guideline on screening for pancreatic cancer in individuals with genetic susceptibility: summary and recommendations – Gastrointestinal Endoscopy

Commentary: New guidelines for pancreatic cancer screening – Beth Israel Deaconess Medical Center

 

Commentary on Twitter

 


Podcast: Gallbladder disease pearls.

14 Jun, 2022 | 10:46h | UTC

#340 Gallbladder Disease – The Curbsiders

 


Case Series | Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit.

13 Jun, 2022 | 10:46h | UTC

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Related: Investigating acute hepatitis of unknown origin in children (several resources on the subject)

 

Commentary on Twitter

 


RCT: Ustekinumab vs. adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn’s disease.

13 Jun, 2022 | 07:56h | UTC

Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn’s disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 


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