Gastroenterology
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
26 Feb, 2021 | 08:17h | UTC
Guidelines for the treatment of irritable bowel syndrome
26 Feb, 2021 | 08:15h | UTC
RCT: Hypothermic machine perfusion in liver transplantation
25 Feb, 2021 | 08:44h | UTCHypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Cold Perfusion Cuts Liver Transplant Complications – MedPage Today
Position Paper: Management of drug-induced liver injury
25 Feb, 2021 | 08:27h | UTC
Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers
24 Feb, 2021 | 02:00h | UTC
Gastrointestinal symptoms common in major depressive disorder, study shows
21 Feb, 2021 | 21:52h | UTCGastrointestinal Symptoms Common in Major Depressive Disorder, Study Shows – Psychiatric News Alert
Multi-parametric CT offers earlier detection for common liver disease
21 Feb, 2021 | 21:37h | UTCMulti-Parametric CT Offers Earlier Detection for Common Liver Disease – Clinical Imaging
Original study: Utility of Multiparametric CT for Identification of High-Risk NAFLD – American Journal of Roentgenology (link to abstract – $ for full-text)
A food allergy epidemic… or just another case of overdiagnosis?
19 Feb, 2021 | 02:13h | UTCA food allergy epidemic… or just another case of overdiagnosis? – The BMJ Opinion
Original study: Food anaphylaxis in the United Kingdom: analysis of national data, 1998-2018 – The BMJ
SR: Concomitant use of levothyroxine and proton pump inhibitors causes a significant increase in TSH concentration
18 Feb, 2021 | 02:48h | UTC
M-A: Role of diet in colorectal cancer incidence
17 Feb, 2021 | 01:12h | UTC
M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome
16 Feb, 2021 | 02:01h | UTC
Commentary on Twitter
Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis "The low-FODMAP diet reduces GI symptoms and improves quality of life in IBS subjects as compared to control diets"https://t.co/tTeRjKOV1O pic.twitter.com/raLdnlDQCJ
— Lukas Schwingshackl (@LSchwingshackl) February 15, 2021
FDA Drug Safety Communication: Initial safety trial results find Tofacitinib, used for arthritis and ulcerative colitis, may increase the risk of serious heart-related problems and cancer
9 Feb, 2021 | 01:00h | UTCCommentary: Arthritis, Colitis Drug Tied to Heart-Related Problems and Cancer – NEJM Journal Watch
RCT: In patients with cirrhosis treated with TIPS, prophylactic rifaximin reduced the risk for Hepatic Encephalopathy
7 Feb, 2021 | 21:10h | UTCThe Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Rifaximin prevents overt hepatic encephalopathy after TIPS – HealthDay
Commentary on Twitter
New findings published in @AnnalsofIM:
In patients with #cirrhosis treated with TIPS, rifaximin was well tolerated and reduced the risk for overt HE. #Rifaximin should therefore be considered for prophylaxis of post-TIPS HE https://t.co/d2p9dfcx3s. pic.twitter.com/M7zwmUxQA3
— Annals of Int Med (@AnnalsofIM) February 2, 2021
Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy
3 Feb, 2021 | 01:20h | UTCRisk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)
Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA
Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
Disorders of the enteric nervous system — a holistic view
2 Feb, 2021 | 01:04h | UTC
Acute Pancreatitis: A Review
28 Jan, 2021 | 01:20h | UTCAcute Pancreatitis: A Review – JAMA (free for a limited period)
Podcast: Acute Pancreatitis Part 1 of 2: Diagnosis
Podcast: Acute Pancreatitis Part 2 of 2: Treatment
Pancreatic Cysts—An Overview and Summary of Society Guidelines, 2021
28 Jan, 2021 | 01:19h | UTCPancreatic Cysts—An Overview and Summary of Society Guidelines, 2021 – JAMA (free for a limited period)
Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70
26 Jan, 2021 | 00:37h | UTCAspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)
Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly
State of the art review: Management of non-alcoholic fatty liver disease
21 Jan, 2021 | 01:13h | UTCManagement of non-alcoholic fatty liver disease – The BMJ
Randomized trial: Pneumatic dilation does not work for persistent dysphagia after antireflux surgery
19 Jan, 2021 | 01:13h | UTCPneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomised sham-controlled clinical trial – Gut (link to abstract – $ for full-text)
Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection
17 Jan, 2021 | 22:00h | UTC
Review: Gastroesophageal reflux disease
17 Jan, 2021 | 21:52h | UTCGastroesophageal Reflux Disease: A Review – JAMA (free for a limited period)
Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection
17 Jan, 2021 | 21:50h | UTCLong-term Safety of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection – Gastroenterology (link to abstract – $ for full-text)
Commentary: Fecal Transplants Safe Long Term for Recurrent C. Diff — But new-onset conditions post-fecal microbiota transplantation need further study – MedPage Today (free registration required)
Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin
14 Jan, 2021 | 01:57h | UTCEditorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis
Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly
Commentary on Twitter
In this RCT comparing 7d oral moxifloxacin vs 2d IV ertapenam 5d oral levofloxacin metronidazole for adults w uncomplicated #appendicitis, Tx success was >65% for both, but oral #antibiotics did not meet noninferiority criteria vs IV PO https://t.co/SwcopsGZTm #VisualAbstract
— JAMA (@JAMA_current) January 12, 2021
Randomized trial: First-line treatment with infliximab vs. conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease
14 Jan, 2021 | 01:27h | UTC