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Gastroenterology

Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy

25 Nov, 2020 | 09:05h | UTC

Colorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)

 


[Abstract Only] In a Phase 2 randomized trial, Semaglutide at high doses improved Nonalcoholic Steatohepatitis (NASH), but with no significant beneficial effects in liver fibrosis

17 Nov, 2020 | 09:31h | UTC

A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Semaglutide Shows Promise in NASH Phase 2 Study – Medscape (free registration required)

 

Commentary on Twitter

 


[Abstract Only] Randomized trial: Intravenous haloperidol more effective than ondansetron for cannabis hyperemesis syndrome

11 Nov, 2020 | 09:08h | UTC

Intravenous Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC): A Randomized, Controlled Trial – Annals of Emergency Medicine

 

Commentary on Twitter

 


Guideline synopsis for follow-up colonoscopy after polypectomy. Repeat Col in 7 to 10 y after 1 to 2 tubular adenomas (TA) < 10 mm; Repeat Col in 3 to 5 y after 3 to 4 TA < 10 mm; Repeat Col in 3 y after 5 to 10 TA < 10 mm; Repeat Col in 3 years after 1 or more TA > 10 mm

9 Nov, 2020 | 01:17h | UTC

Recommendations for Follow-up Colonoscopy After Polypectomy – JAMA (free for a limited period)

Author interview: New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy

Original guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology

 


USPSTF draft statement now recommends starting colorectal cancer screening at 45

28 Oct, 2020 | 08:57h | UTC

Draft Recommendation Statement: Colorectal Cancer Screening – U.S. Preventive Services Task Force

Commentaries: Colorectal cancer screening should start five years earlier — at 45 — expert panel says – STAT AND USPSTF Lowers Colorectal Cancer Screening Age to 45 in Draft Recommendation – NEJM Journal Watch

 


Clinical review: New advances in the diagnosis and management of hepatocellular carcinoma

28 Oct, 2020 | 08:47h | UTC

New advances in the diagnosis and management of hepatocellular carcinoma – The BMJ (free for a limited period)

 

Commentary on Twitter

 


Meta-analysis: Drugs for preventing postoperative nausea and vomiting in adults after general anesthesia

21 Oct, 2020 | 09:13h | UTC

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis – Cochrane Library

Summary: Which medicines work best to prevent people from being sick (vomiting) after an operation? – Cochrane Library

 

Commentary on Twitter

 


Systematic review: Management of colonic diverticulitis

16 Oct, 2020 | 09:25h | UTC

Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality

Full report: Management of Colonic Diverticulitis

Evidence summary: Management of Colonic Diverticulitis

 


Non-respiratory presentations of COVID-19, a clinical review

14 Oct, 2020 | 09:33h | UTC

Non-respiratory presentations of COVID-19, a clinical review – The American Journal of Emergency Medicine

 


Esophageal emergencies: Another important cause of acute chest pain

12 Oct, 2020 | 00:30h | UTC

Esophageal emergencies: another important cause of acute chest pain – Insights into Imaging

 


[Abstract Only] A Randomized trial comparing antibiotics with appendectomy for appendicitis

6 Oct, 2020 | 00:44h | UTC

A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Benefits, risks seen with antibiotics-first for appendicitis – University of Washington School of Medicine

Infographic: Deciding Between Antibiotics & Surgery for Appendicitis: Findings from the CODA Study

 

Commentary on Twitter

 


Virologists who discovered hepatitis C win medicine Nobel

6 Oct, 2020 | 00:12h | UTC

Virologists who discovered hepatitis C win medicine Nobel – Nature

See also: Medicine Nobel honors three scientists for discoveries on hepatitis C virus – Science AND Trio wins Nobel Prize in medicine for discovery of hepatitis C virus – STAT

 


Cohort study: Fecal microbiota transplant is highly effective in real-world practice

4 Oct, 2020 | 23:10h | UTC

Fecal Microbiota Transplant is Highly Effective in Real-World Practice: Initial Results from the FMT National Registry – Gastroenterology (link to abstract – $ for full-text)

News Release: AGA releases largest real-world report on safety and effectiveness of fecal microbiota transplantation (FMT) – American Gastroenterological Association

Commentary: 9 in 10 Cured a Month After Fecal Microbiota Transplantation for C. diff – NEJM Journal Watch

 


Editorial – Stress ulcer prophylaxis: Is mortality a useful endpoint?

30 Sep, 2020 | 09:31h | UTC

Stress ulcer prophylaxis: Is mortality a useful endpoint? – Intensive Care Medicine

 

Commentary on Twitter

 


Gastrointestinal complications in critically ill patients with and without COVID-19

25 Sep, 2020 | 02:44h | UTC

Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19 – JAMA

 

Commentary on Twitter

 


Lower-dose zinc for childhood diarrhea — a randomized, multicenter trial

24 Sep, 2020 | 09:21h | UTC

Lower-Dose Zinc for Childhood Diarrhea — A Randomized, Multicenter Trial – New England Journal of Medicine

 

Commentary on Twitter

 


Things we do for no reason: Routine correction of elevated INR and thrombocytopenia prior to paracentesis in patients with cirrhosis

24 Sep, 2020 | 09:17h | UTC

Things We Do for No Reason™: Routine Correction of Elevated INR and Thrombocytopenia Prior to Paracentesis in Patients with Cirrhosis – Journal of Hospital Medicine

See collection: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine

 


Multisystem effects of COVID-19: A concise review for practitioners

16 Sep, 2020 | 09:14h | UTC

Multisystem effects of COVID-19: A concise review for practitioners – Postgraduate Medicine

 


State of the art review: Hepatorenal syndrome

15 Sep, 2020 | 08:41h | UTC

Hepatorenal syndrome: pathophysiology, diagnosis, and management – The BMJ (free for a limited period)

 

Commentary on Twitter

 


ACG Guidelines: Diagnosis and management of achalasia

11 Sep, 2020 | 01:18h | UTC

ACG Clinical Guidelines: Diagnosis and Management of Achalasia – The American Journal of Gastroenterology

 

Commentary on Twitter

 


[Abstract Only] Randomized trial: Aspirin increases major GI bleeding risk by 60% in older individuals

6 Sep, 2020 | 21:30h | UTC

Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial – Gut

Source: EvidenceAlerts

 

Commentary on Twitter

 


[Preprint] Diarrhea and vomiting may be a key sign of Covid-19 in children

4 Sep, 2020 | 02:12h | UTC

Diarrhoea and vomiting may be key sign of Covid in children – The Guardian

Original Study: Seroprevalence of SARS-CoV-2 antibodies in children – A prospective multicentre cohort study – medRxiv

 

Commentary on Twitter

 


AGA Guidelines on the gastrointestinal evaluation of iron deficiency anemia

1 Sep, 2020 | 06:02h | UTC

AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia – Gastroenterology

 


Prevalence, risk factors, and outcomes of hospitalized patients with COVID-19 presenting as acute pancreatitis

28 Aug, 2020 | 08:41h | UTC

Prevalence, risk factors, and outcomes of hospitalized patients with COVID-19 presenting as acute pancreatitis – Gastroenterology

Commentary: Covid-19 can present with pancreatitis – MedicalResearch.com

 


Guideline synopsis: Ulcerative colitis in adults

28 Aug, 2020 | 08:38h | UTC

Ulcerative Colitis in Adults – JAMA

Podcast: Update on Ulcerative Colitis—2020

Original Guideline: AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis – Gastroenterology

 


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