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Gastroenterology

Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis

26 Feb, 2021 | 08:17h | UTC

Drains, Germs, or Steel: Multidisciplinary Management of Acute Colonic Diverticulitis – Digestive Diseases and Sciences

 


Guidelines for the treatment of irritable bowel syndrome

26 Feb, 2021 | 08:15h | UTC

Evidence-based clinical practice guidelines for irritable bowel syndrome 2020 – Journal of Gastroenterology

Related: ACG Clinical Guideline: Management of Irritable Bowel Syndrome – The American Journal of Gastroenterology

 


RCT: Hypothermic machine perfusion in liver transplantation

25 Feb, 2021 | 08:44h | UTC

Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Cold Perfusion Cuts Liver Transplant Complications – MedPage Today

 


Position Paper: Management of drug-induced liver injury

25 Feb, 2021 | 08:27h | UTC

Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver – Annals of Hepatology

 


Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers

24 Feb, 2021 | 02:00h | UTC

Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers – News Medical

Original study: Gastroesophageal reflux disease: A risk factor for laryngeal squamous cell carcinoma and esophageal squamous cell carcinoma in the NIH‐AARP Diet and Health Study cohort – Cancer

 


Gastrointestinal symptoms common in major depressive disorder, study shows

21 Feb, 2021 | 21:52h | UTC

Gastrointestinal Symptoms Common in Major Depressive Disorder, Study Shows – Psychiatric News Alert

Original study: Gastrointestinal Symptoms During Depressive Episodes in 3256 Patients with Major Depressive Disorders: Findings from the NSSD – Journal of Affective Disorders

 


Multi-parametric CT offers earlier detection for common liver disease

21 Feb, 2021 | 21:37h | UTC

Multi-Parametric CT Offers Earlier Detection for Common Liver Disease – Clinical Imaging

Original study: Utility of Multiparametric CT for Identification of High-Risk NAFLD – American Journal of Roentgenology (link to abstract – $ for full-text)

 


A food allergy epidemic… or just another case of overdiagnosis?

19 Feb, 2021 | 02:13h | UTC

A food allergy epidemic… or just another case of overdiagnosis? – The BMJ Opinion

Original study: Food anaphylaxis in the United Kingdom: analysis of national data, 1998-2018 – The BMJ

 


SR: Concomitant use of levothyroxine and proton pump inhibitors causes a significant increase in TSH concentration

18 Feb, 2021 | 02:48h | UTC

Concomitant Use of Levothyroxine and Proton Pump Inhibitors in Patients with Primary Hypothyroidism: a Systematic Review – Journal of General Internal Medicine

 


M-A: Role of diet in colorectal cancer incidence

17 Feb, 2021 | 01:12h | UTC

Role of Diet in Colorectal Cancer Incidence: Umbrella Review of Meta-analyses of Prospective Observational Studies – JAMA Network Open

 


M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome

16 Feb, 2021 | 02:01h | UTC

Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis – European Journal of Nutrition

 

Commentary on Twitter

 


FDA Drug Safety Communication: Initial safety trial results find Tofacitinib, used for arthritis and ulcerative colitis, may increase the risk of serious heart-related problems and cancer

9 Feb, 2021 | 01:00h | UTC

Xeljanz, Xeljanz XR (tofacitinib): Drug Safety Communication – Initial Safety Trial Results Find Increased Risk of Serious Heart-related Problems and Cancer with Arthritis and Ulcerative Colitis Medicine – U.S. Food & Drug Administration

Commentary: Arthritis, Colitis Drug Tied to Heart-Related Problems and Cancer – NEJM Journal Watch

 


RCT: In patients with cirrhosis treated with TIPS, prophylactic rifaximin reduced the risk for Hepatic Encephalopathy

7 Feb, 2021 | 21:10h | UTC

The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Rifaximin prevents overt hepatic encephalopathy after TIPS – HealthDay

 

Commentary on Twitter

 


Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy

3 Feb, 2021 | 01:20h | UTC

Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)

Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA

Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology

 


Disorders of the enteric nervous system — a holistic view

2 Feb, 2021 | 01:04h | UTC

Disorders of the enteric nervous system — a holistic view – Nature Reviews Gastroenterology & Hepatology

 


Acute Pancreatitis: A Review

28 Jan, 2021 | 01:20h | UTC

Acute Pancreatitis: A Review – JAMA (free for a limited period)

Podcast: Acute Pancreatitis Part 1 of 2: Diagnosis

Podcast: Acute Pancreatitis Part 2 of 2: Treatment

 


Pancreatic Cysts—An Overview and Summary of Society Guidelines, 2021

28 Jan, 2021 | 01:19h | UTC

Pancreatic Cysts—An Overview and Summary of Society Guidelines, 2021 – JAMA (free for a limited period)

 


Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70

26 Jan, 2021 | 00:37h | UTC

Aspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)

Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly

 


State of the art review: Management of non-alcoholic fatty liver disease

21 Jan, 2021 | 01:13h | UTC

Management of non-alcoholic fatty liver disease – The BMJ

 


Randomized trial: Pneumatic dilation does not work for persistent dysphagia after antireflux surgery

19 Jan, 2021 | 01:13h | UTC

Pneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomised sham-controlled clinical trial – Gut (link to abstract – $ for full-text)

 


Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection

17 Jan, 2021 | 22:00h | UTC

Proton pump inhibitor use and risk for recurrent Clostridioides difficile infection: A systematic review & meta-analysis – Clinical Microbiology and Infection

 


Review: Gastroesophageal reflux disease

17 Jan, 2021 | 21:52h | UTC

Gastroesophageal Reflux Disease: A Review – JAMA (free for a limited period)

 


Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection

17 Jan, 2021 | 21:50h | UTC

Long-term Safety of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection – Gastroenterology (link to abstract – $ for full-text)

Commentary: Fecal Transplants Safe Long Term for Recurrent C. Diff — But new-onset conditions post-fecal microbiota transplantation need further study – MedPage Today (free registration required)

 


Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

14 Jan, 2021 | 01:57h | UTC

Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial – JAMA

Editorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis

Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly

 

Commentary on Twitter

 


Randomized trial: First-line treatment with infliximab vs. conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease

14 Jan, 2021 | 01:27h | UTC

First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease: an open-label multicentre randomised controlled trial – Gut

 


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