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Evidence-based Medicine

Perspective | Ensuring an accurate scientific record in an era of pre-print servers.

1 Sep, 2022 | 11:38h | UTC

Ensuring an Accurate Scientific Record in an Era of Pre-print Servers – Deutsches Ärzteblatt International

 

Perpetual Observational Studies | New strategies to support efficient implementation of observational studies and randomized trials in infectious diseases.

26 Aug, 2022 | 13:17h | UTC

Perpetual Observational Studies: New strategies to support efficient implementation of observational studies and randomized trials in infectious diseases – Clinical Infectious Diseases

 

Editorial | Keeping meta-analyses fresh.

25 Aug, 2022 | 12:09h | UTC

Keeping Meta-analyses Fresh – JAMA Network Open

 

Using individual participant data to improve network meta-analysis projects.

24 Aug, 2022 | 14:00h | UTC

Using individual participant data to improve network meta-analysis projects – BMJ Evidence-Based Medicine

 

Commentary on Twitter

 

Evaluating how clear the questions being investigated in randomized trials are: systematic review of estimands.

24 Aug, 2022 | 13:59h | UTC

Evaluating how clear the questions being investigated in randomised trials are: systematic review of estimands – The BMJ

 

Commentary from the author Twitter (thread – click for more)

 

Reporting guideline for overviews of reviews of healthcare interventions: development of the PRIOR statement.

16 Aug, 2022 | 13:31h | UTC

Reporting guideline for overviews of reviews of healthcare interventions: development of the PRIOR statement – The BMJ

 

Perspective | Pragmatism in clinical trials: essential, not optional.

15 Aug, 2022 | 12:15h | UTC

Pragmatism in clinical trials: essential, not optional – European Journal of Cardiology (free for a limited period)

 

Commentary on Twitter

 

Perspective | How to disseminate clinical research.

12 Aug, 2022 | 15:06h | UTC

How to disseminate clinical research – Anaesthesia

 

Commentary on Twitter

 

Advancing digital health applications: priorities for innovation in real-world evidence generation.

10 Aug, 2022 | 12:15h | UTC

Advancing digital health applications: priorities for innovation in real-world evidence generation – The Lancet Digital Health

 

Is the contemporary care of older persons with acute coronary syndrome evidence-based?

8 Aug, 2022 | 11:48h | UTC

Is the contemporary care of the older persons with acute coronary syndrome evidence-based? – European Heart Journal Open

 

Commentary from the author on Twitter

 

Statistical significance and its critics: practicing damaging science, or damaging scientific practice?

8 Aug, 2022 | 11:35h | UTC

Statistical significance and its critics: practicing damaging science, or damaging scientific practice? – Synthese

Related:

Bayesian interpretation of p values in clinical trials – BMJ Evidence-Based Medicine

Scientists rise up against statistical significance – Nature

It’s time to talk about ditching statistical significance – Nature

PulmCrit- .050 shades of grey in p-value cutoffs

Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations – European Journal of Epidemiology

What a nerdy debate about p-values shows about science — and how to fix it – VOX

Big names in statistics want to shake up much-maligned P value – Nature News

‘One-size-fits-all’ threshold for P values under fire – Nature News

Statisticians issue warning over misuse of P values – Nature News

Understanding common misconceptions about p-values – The 20% Statistician

The clinician’s guide to p values, confidence intervals, and magnitude of effects – Eye (if the link is paywalled, try this one)

 

Viewpoint | Deimplementation of low-value care in surgery.

4 Aug, 2022 | 14:43h | UTC

Deimplementation of Low-Value Care in Surgery – JAMA Surgery (free for a limited period)

 

Designing Infographics | Visual representations for enhancing education, communication, and scientific research.

3 Aug, 2022 | 14:24h | UTC

Designing Infographics: Visual Representations for Enhancing Education, Communication, and Scientific Research – Journal of Korean Medical Science

Related:

Creating Effective Infographics and Visual Abstracts to Disseminate Research and Facilitate Medical Education on Social Media

As scientists take to Twitter, study shows power of ‘visual abstract’ graphics – Scienmag

See also: an open-source primer on visual abstracts

 

When underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy.

1 Aug, 2022 | 12:12h | UTC

When underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy – Nature Reviews Rheumatology (if the link is paywalled, try this one in PMC)

 

Commentary on Twitter

 

Doctors tend to have unrealistic expectations of the success of multi-step medical procedures.

18 Jul, 2022 | 11:42h | UTC

News Release: Doctors tend to have unrealistic expectations of the success of multi-step medical procedures – News Medical / University of Utah Health

Original Study: Analysis of Physicians’ Probability Estimates of a Medical Outcome Based on a Sequence of Events – JAMA Network Open

 

Commentary on Twitter (thread – click for more)

 

How to bounce back from a PhD-project failure.

14 Jul, 2022 | 12:59h | UTC

How to bounce back from a PhD-project failure – Nature

 

Designing and conducting adaptive trials to evaluate interventions in health services and implementation research: practical considerations.

12 Jul, 2022 | 12:27h | UTC

Designing and conducting adaptive trials to evaluate interventions in health services and implementation research: practical considerations – BMJ Medicine

 

Commentary on Twitter

 

The (R)evolution of social media in oncology: engage, enlighten, and encourage.

11 Jul, 2022 | 12:33h | UTC

The (R)evolution of Social Media in Oncology: Engage, Enlighten, and Encourage – Cancer Discovery

Related:

Twitter promotion is associated with higher citation rates of cardiovascular articles: the ESC Journals Randomized Study – European Society of Cardiology (link to abstract – $ for full-text)

Randomized Trial: Twitter Promotion Increases Citation Rates of Cardiovascular Articles

Does Tweeting Improve Citations? One-Year Results from the TSSMN Prospective Randomized Trial

A critical review on altmetrics: can we measure the social impact factor?

As scientists take to Twitter, study shows power of ‘visual abstract’ graphics

Riding the Twitter wave: Enthusiasm for the social media platform changed science communication during the pandemic—but will it last?

Optimizing the use of Twitter for research dissemination: The “Three Facts and a Story” randomized-controlled trial.

Perspective: How Twitter is Changing Medical Research

Keeping Up With Cardiology: Old-School Learning Versus the Twittersphere – TCTMD

Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets

Rise of the Tweetorial – Precious Bodily Fluids

Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine

University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC

Twitter-Based Medicine: How Social Media is Changing the Public’s View of Medicine – The Health Care Blog

What’s your doctor reading? How social media is disrupting medical education – National Post

 

Perspective | How to find, read and organize papers.

8 Jul, 2022 | 11:57h | UTC

How to find, read and organize papers – Nature

 

How to write statistical analysis section in medical research.

29 Jun, 2022 | 12:03h | UTC

How to write statistical analysis section in medical research – Journal of Investigative Medicine

 

Commentary on Twitter

Under a http://creativecommons.org/licenses/by-nc/4.0/ license

 

Current recommendations/practices for anonymizing data from clinical trials in order to make it available for sharing: A scoping review.

29 Jun, 2022 | 11:17h | UTC

Current recommendations/practices for anonymising data from clinical trials in order to make it available for sharing: A scoping review – Clinical Trials

 

Commentary on Twitter

 

Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19.

27 Jun, 2022 | 11:49h | UTC

Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19 – The Lancet Respiratory Medicine

Commentary: Early-phase clinical trials in a pandemic: learning from the response to COVID-19 – The Lancet Respiratory Medicine

 

Commentary on Twitter

 

New COVID drugs face delays as trials grow more difficult.

24 Jun, 2022 | 11:47h | UTC

New COVID drugs face delays as trials grow more difficult – Nature

 

Research must do no harm: new guidance addresses all studies relating to people.

24 Jun, 2022 | 11:46h | UTC

Research must do no harm: new guidance addresses all studies relating to people – Nature

See Guidance: Research Ethics – Nature Portfolio

 

Perspective | Four areas of health innovation boosted by the pandemic.

24 Jun, 2022 | 11:36h | UTC

Four areas of health innovation boosted by the pandemic – Nature Medicine

 

Commentary on Twitter

 

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