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Evidence-based Medicine

Editorial | ChatGPT is fun, but not an author

27 Jan, 2023 | 12:20h | UTC

ChatGPT is fun, but not an author – Science

Related:

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Abstracts written by ChatGPT fool scientists

 


The digitization and decentralization of clinical trials

26 Jan, 2023 | 12:43h | UTC

The Digitization and Decentralization of Clinical Trials – Mayo Clinic Proceedings

 


Analysis | Finding bias before the first patient is enrolled

26 Jan, 2023 | 12:42h | UTC

Finding Bias Before the First Patient is Enrolled – Sensible Medicine

 


ChatGPT listed as author on research papers: many scientists disapprove

24 Jan, 2023 | 14:36h | UTC

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Related: Abstracts written by ChatGPT fool scientists

 


Perspective | The case of statins, diabetes, and bias in observational studies

24 Jan, 2023 | 14:35h | UTC

The Case of Statins, Diabetes, and Bias in Observational Studies – Sensible Medicine

 


FDA no longer needs to require animal tests before human drug trials

24 Jan, 2023 | 14:32h | UTC

FDA no longer needs to require animal tests before human drug trials – Science

See also: The FDA no longer requires all drugs to be tested on animals before human trials – NPR

 


Perspective | The next generation of evidence-based medicine

23 Jan, 2023 | 13:37h | UTC

The next generation of evidence-based medicine – Nature Medicine

Commentary: What does the future of clinical trials and evidence-based medicine look like? – News Medical

 

Commentary on Twitter

 


SR | Mortality as a measure of treatment effect in clinical trials recruiting critically ill patients

23 Jan, 2023 | 13:27h | UTC

Mortality As a Measure of Treatment Effect in Clinical Trials Recruiting Critically Ill Patients – Critical Care Medicine (free for a limited period)

 


An overview of methodological considerations regarding adaptive stopping, arm dropping, and randomization in clinical trials

20 Jan, 2023 | 14:27h | UTC

An overview of methodological considerations regarding adaptive stopping, arm dropping, and randomization in clinical trials – Journal of Clinical Epidemiology

 

Commentary from the author on Twitter

Under a Creative Commons Attribution (CC BY 4.0) License

 


Abstracts written by ChatGPT fool scientists

18 Jan, 2023 | 14:29h | UTC

Abstracts written by ChatGPT fool scientists – Nature

Original Study (preprint): Comparing scientific abstracts generated by ChatGPT to original abstracts using an artificial intelligence output detector, plagiarism detector, and blinded human reviewers – bioRxiv

 


Opinion | The American Academy of Pediatrics is pushing drugs and surgery for obesity

17 Jan, 2023 | 13:27h | UTC

The American Academy of Pediatrics is Pushing Drugs & Surgery for Obesity – Sensible Medicine

Original article and commentaries: AAP Guideline | Evaluation and treatment of children and adolescents with obesity

 


Analysis of questionable research practices in 163,129 randomized controlled trials

13 Jan, 2023 | 13:38h | UTC

Indicators of questionable research practices were identified in 163,129 randomized controlled trials – Journal of Clinical Epidemiology

 


The dangers of non-randomized, observational studies: experience from the COVID-19 epidemic

12 Jan, 2023 | 13:26h | UTC

The dangers of non-randomized, observational studies: experience from the COVID-19 epidemic – Journal of Antimicrobial Chemotherapy

 


Perspective | The limits of shared decision making

11 Jan, 2023 | 14:28h | UTC

The limits of shared decision making – BMJ Evidence-Based Medicine

 


Restoring mortality data in the FOURIER trial of evolocumab in patients with CVD: a reanalysis based on regulatory data

10 Jan, 2023 | 14:49h | UTC

Restoring mortality data in the FOURIER cardiovascular outcomes trial of evolocumab in patients with cardiovascular disease: a reanalysis based on regulatory data – BMJ Open

Commentaries: 

Yet Another Story on Re-Analyzing a Major Trial – Sensible Medicine

Study Alleges Mortality Miscount in FOURIER Trial; TIMI Group Disagrees – TCTMD

Experts Issue Caution for Evolocumab Following New Review of FOURIER Data; Amgen Disputes the Claims – AJMC

 


Nature announces support for authors from over 70 countries to publish open access

10 Jan, 2023 | 14:46h | UTC

Nature announces support for authors from over 70 countries to publish open access – Springer Nature group

 

Commentary on Twitter

 


SR | Design and conduct of randomized clinical trials evaluating surgical innovations in ophthalmology

10 Jan, 2023 | 14:04h | UTC

Design and conduct of randomized clinical trials evaluating surgical innovations in ophthalmology: A systematic review – American Journal of Ophthalmology (free for a limited period)

 


ESC/AHA/ACC/WHF Joint Opinion | Randomized trials fit for the 21st century

9 Jan, 2023 | 14:44h | UTC

Randomized Trials Fit for the 21st Century: A Joint Opinion From the European Society of Cardiology, American Heart Association, American College of Cardiology, and the World Heart Federation – Circulation

Commentaries:

It’s Time to Revamp How Clinical Trials Are Done, Say Cardiology Societies – TCTMD

World Cardiology Societies Call for Reinvention of Randomized Clinical Trials – Cardiac Interventions Today

 

Commentary on Twitter

 


Review | Conducting umbrella reviews.

16 Dec, 2022 | 13:21h | UTC

Conducting umbrella reviews – BMJ Medicine

 


Perspective | The importance of long-term follow up of participants in clinical trials.

16 Dec, 2022 | 13:13h | UTC

The importance of long-term follow up of participants in clinical trials – British Journal of Cancer

 


Guidelines for reporting outcomes in trial protocols: The SPIRIT-Outcomes 2022 Extension.

15 Dec, 2022 | 13:46h | UTC

Guidelines for Reporting Outcomes in Trial Protocols: The SPIRIT-Outcomes 2022 Extension – JAMA (free for a limited period)

See also: Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension – JAMA (free for a limited period)

 

Commentary on Twitter

 


Guidelines for reporting outcomes in trial reports: The CONSORT-Outcomes 2022 Extension.

15 Dec, 2022 | 13:45h | UTC

Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension – JAMA (free for a limited period)

See also: Guidelines for Reporting Outcomes in Trial Protocols: The SPIRIT-Outcomes 2022 Extension – JAMA (free for a limited period)

 

Commentary on Twitter

 


Consensus Statement | Continuous glucose monitoring and metrics for clinical trials.

15 Dec, 2022 | 13:42h | UTC

Continuous glucose monitoring and metrics for clinical trials: an international consensus statement – The Lancet Diabetes & Endocrinology (free registration required)

 

Commentary on Twitter

 


Comparison of clinical study results reported in medRxiv preprints vs. subsequently published peer-reviewed journal articles.

12 Dec, 2022 | 12:42h | UTC

Comparison of Clinical Study Results Reported in medRxiv Preprints vs Peer-reviewed Journal Articles – JAMA Network Open

Author Interview: Clinical Study Results Reported in medRxiv Preprints vs Peer-reviewed Journals

 


Perspective | How to manage your time as a researcher.

8 Dec, 2022 | 12:45h | UTC

How to manage your time as a researcher – Nature

 


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