Pediatrics – Neurology
RCT: Oxytocin does not improve social functioning in children with autism spectrum disorder.
14 Oct, 2021 | 09:52h | UTCOriginal study: Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder – New England Journal of Medicine
RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.
11 Oct, 2021 | 23:58h | UTCNews release: Aerobic exercise after a sport-related concussion speeds recovery in adolescent athletes – University at Buffalo
Related:
Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion
RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.
Commentaries on Twitter
RCT study in @TheLancet shows adolescents who sub-threshold aerobic exercise 20 mins/ day for 4 weeks starting within 10 days of a concussion are 48% less likely to get prolonged symptoms. https://t.co/1tafsQHrXt
— Dr Ademola Adejuwon (@SmileySportyDoc) October 2, 2021
Sport-related #concussion is a major public health issue in US adolescents
This new RCT of aerobic exercise vs stretching found exercise sped up recovery and reduced risk for persistent post-concussive symptomshttps://t.co/jP30N1eJEQ pic.twitter.com/ux42VSMfSr
— The Lancet Child & Adolescent Health (@LancetChildAdol) October 1, 2021
Neurological Effects of COVID-19 in Children.
1 Oct, 2021 | 10:40h | UTCNeurological Effects of COVID-19 in Children – Pediatric Clinics of North America
RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.
21 Sep, 2021 | 09:01h | UTCEffect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)
Commentaries:
Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian
Commentary on Twitter
An Australian randomized clinical trial found that ‘pre-emptive’ therapy during infancy reduced #autism diagnostic behaviors and improved language ability across early childhood https://t.co/Sybbu4hRWL
— JAMA Pediatrics (@JAMAPediatrics) September 20, 2021
RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.
12 Sep, 2021 | 21:38h | UTCOriginal study: Effect of Screen Time on Recovery From Concussion: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary on Twitter
The use of electronic screen time in the first 48 hours after sustaining a concussion is associated with a longer time to recovery, a single-center randomized-clinical trial reports https://t.co/PFAj5OoqNc
— JAMA Pediatrics (@JAMAPediatrics) September 7, 2021
[Preprint] Impact of the COVID-19 pandemic on early child cognitive development: initial findings in a longitudinal observational study of child health.
16 Aug, 2021 | 01:11h | UTC
Commentary on Twitter (thread – click for more)
Preprint on the development of children born before and during the pandemic in the US.
"We find that children born during the pandemic have significantly reduced verbal, motor, and overall cognitive performance compared to children born pre-pandemic."
1/https://t.co/NInexSUDAi— Prof Francois Balloux (@BallouxFrancois) August 15, 2021
European guideline and expert statements on the management of narcolepsy in adults and children.
13 Aug, 2021 | 09:02h | UTC
RCT: Therapeutic hypothermia may cause harm in moderate or severe neonatal encephalopathy in low-income and middle-income countries.
5 Aug, 2021 | 08:43h | UTCNews release: Brain injury treatment may cause harm in low and middle income nations – Imperial College London
Commentary: Hypoxic ischaemic encephalopathy in low resource settings—time to stop cooling? – The Lancet Global Health
Cohort study: Neurological manifestations of SARS-CoV-2 infection in hospitalized children and adolescents in the UK – “around 1 in 20 of children hospitalized with COVID-19 develop brain or nerve complications linked to the viral infection”.
26 Jul, 2021 | 02:58h | UTCCommentaries:
Commentary on Twitter
A UK national prospective study of brain involvement in children hospitalized with covid: wide range of neurologic complications in 51 kidshttps://t.co/4JvjbthgH4 @LancetChildAdol pic.twitter.com/IiXF9bVmKz
— Eric Topol (@EricTopol) July 14, 2021
Systematic review: Prophylactic drug management for febrile seizures in children.
9 Jul, 2021 | 09:51h | UTCProphylactic drug management for febrile seizures in children – Cochrane Library
Summary: Prophylactic drug management for febrile seizures in children
Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.
25 Jun, 2021 | 10:15h | UTCNews release: Strict Rest Slows Recovery after Sports-Related Concussions – American College of Sports Medicine
M-A: Parenting interventions to promote early child development in the first three years of life.
3 Jun, 2021 | 10:37h | UTC
Study suggests it is safe to discontinue antiseizure medication for most neonates with acute symptomatic seizures prior to discharge from the hospital.
27 May, 2021 | 08:14h | UTCSafety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures – JAMA Neurology (free for a limited period)
Editorial: Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures—Primum non nocere – JAMA Neurology (free for a limited period)
Commentaries: Stopping Antiseizure Medication After Acute Symptomatic Neonatal Seizures Is Found to Be Safe – Neurology Today AND Babies with Seizures May Be Overmedicated – Michigan Medicine
Commentary on Twitter
New CER study on @JAMANeuro finds no difference in functional neurodevelopment or epilepsy at 24 mnths in children whose antiseizure meds was discont'd vs maintained at discharge after resolution of acute symptomatic neonatal seizures: https://t.co/yvKbrJuCvQ #ebneoalerts #neoEBM pic.twitter.com/810weSUSgb
— Evidence-Based Neo (@EBNEO) May 26, 2021
Cohort study: Babies surviving Group B strep more likely to require special educational support.
21 May, 2021 | 08:27h | UTC
M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.
21 May, 2021 | 08:24h | UTC
Commentary on Twitter
This metanalysis found positive urinalysis alone is not an indication for LP in well looking febrile infants >28 days old. Prevalence among UA-positive infants: 0.4% vs UA-negative infants: 0.5%. https://t.co/dTzCiLHrSg
— JAMA Network Open (@JAMANetworkOpen) May 12, 2021
Systematic review: Cognitive behavioral therapy may improve outcomes for autism spectrum disorders.
21 May, 2021 | 08:21h | UTCCognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review – Pediatrics (link to abstract – $ for full-text)
Guideline: Early intervention for children aged 0 to 2 years with or at high risk of cerebral palsy.
19 May, 2021 | 08:35h | UTCEarly Intervention for Children Aged 0 to 2 Years With or at High Risk of Cerebral Palsy: International Clinical Practice Guideline Based on Systematic Reviews – JAMA Pediatrics (free for a limited period)
Editorial: Early Intervention in Cerebral Palsy and Beyond (free for a limited period)
NICE Guideline Update | Headaches in over 12s: diagnosis and management.
18 May, 2021 | 07:14h | UTCHeadaches in over 12s: diagnosis and management – National Institute for Health and Care Excellence
Population-based cohort study: Youngest children in class are more likely to be diagnosed with a learning disability
11 May, 2021 | 09:08h | UTCCommentary: Youngest children in class are more likely to be diagnosed with a learning disability – University of Turku
Cohort study: Risk of developmental difficulties remains high among children born early
5 May, 2021 | 08:24h | UTCNeurodevelopmental outcomes at age 5 among children born preterm: EPIPAGE-2 cohort study – The BMJ
News release: Risk of developmental difficulties remains high among children born early – The BMJ
Commentary on Twitter
Children born preterm remain at high risk of developmental difficulties that can affect their behaviour and ability to learn, finds new research https://t.co/0A1aIQWWqk #BMJResearch
— The BMJ (@bmj_latest) May 2, 2021
M-A: A third of kids develop a mental health problem after concussion
4 May, 2021 | 08:35h | UTCNews Release: A third of kids develop a mental health problem after concussion – Murdoch Childrens Research Institute
Original Study: Mental health after paediatric concussion: a systematic review and meta-analysis – British Journal of Sports Medicine
Choosing Wisely: Five things clinicians and patients should question in Neurological Surgery in Children
28 Mar, 2021 | 22:04h | UTCAmerican Academy of Pediatrics – Section on Neurological Surgery – Choosing Wisely
Commentary: Choosing Wisely: 5 Things to Avoid in Pediatric Neurologic Surgery – NEJM Journal Watch
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome
10 Mar, 2021 | 08:29h | UTC
Commentary on Twitter
Neurologic involvement in US children and adolescents hospitalized for #COVID19 is common, mostly transient, and ranges from mild to life threatening https://t.co/Dy7fZhSMDR
— JAMA Neurology (@JAMANeuro) March 5, 2021
RCT: Among children with Myelomeningocele, long term results confirm the benefits of prenatal repair compared to standard postnatal repair
10 Feb, 2021 | 01:28h | UTCPrenatal Repair and Physical Functioning Among Children With Myelomeningocele: A Secondary Analysis of a Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Editorial: Long-term Outcomes of Children After Fetal Surgery for Spina Bifida—Toward Sustainability – JAMA Pediatrics (free for a limited period)
Commentaries: Spina Bifida Repair: The Sooner the Better – Physician’s Weekly AND Prenatal Myelomeningocele Repair Tied to Better Function – HealthDay
Commentary on Twitter
Previous work reported that prenatal versus postnatal repair of myelomeningocele resulted in improved physical functioning. A secondary analysis at #jamapeds reports that these improvements persist into school age. https://t.co/2aehk5L6pi pic.twitter.com/hASLEUcvqm
— JAMA Pediatrics (@JAMAPediatrics) February 9, 2021
WHO issues new guidelines on the management of chronic pain in children
29 Jan, 2021 | 01:37h | UTCGuideline: Guidelines on the management of chronic pain in children – World Health Organization