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Pediatrics – Neurology

RCT: Oxytocin does not improve social functioning in children with autism spectrum disorder.

14 Oct, 2021 | 09:52h | UTC

News release: Oxytocin does not improve social functioning in children with autism spectrum disorder, NIH-funded study suggests – National Institutes of Health

Original study: Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder – New England Journal of Medicine

 


RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.

11 Oct, 2021 | 23:58h | UTC

Early targeted heart rate aerobic exercise versus placebo stretching for sport-related concussion in adolescents: a randomised controlled trial – The Lancet Child & Adolescent Health

News release: Aerobic exercise after a sport-related concussion speeds recovery in adolescent athletes – University at Buffalo

Related:

Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

 

Commentaries on Twitter

 


Neurological Effects of COVID-19 in Children.

1 Oct, 2021 | 10:40h | UTC

Neurological Effects of COVID-19 in Children – Pediatric Clinics of North America

 


RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.

21 Sep, 2021 | 09:01h | UTC

Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)

Commentaries:

Intervening Before 18 Months May Reduce Odds of Autism Diagnosis in Babies Identified at High Risk – Psychiatric News Alert

Expert reaction to trial looking at the effect of a pre-emptive intervention in children showing early signs of autism on developmental outcomes – Science Media Centre

Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian

 

Commentary on Twitter

 


RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

12 Sep, 2021 | 21:38h | UTC

News release: Limiting screen time for young adults after concussion results in shorter duration of symptoms – University of Massachusetts Medical School

Original study: Effect of Screen Time on Recovery From Concussion: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

 

Commentary on Twitter

 


[Preprint] Impact of the COVID-19 pandemic on early child cognitive development: initial findings in a longitudinal observational study of child health.

16 Aug, 2021 | 01:11h | UTC

Impact of the COVID-19 Pandemic on Early Child Cognitive Development: Initial Findings in a Longitudinal Observational Study of Child Health – medRxiv

Commentary: Children born during pandemic have lower IQs, US study finds – Researchers blame lack of stimulation as parents balanced childcare with working from home – The Guardian

 

Commentary on Twitter (thread – click for more)

 


European guideline and expert statements on the management of narcolepsy in adults and children.

13 Aug, 2021 | 09:02h | UTC

European guideline and expert statements on the management of narcolepsy in adults and children – European Journal of Neurology

 


RCT: Therapeutic hypothermia may cause harm in moderate or severe neonatal encephalopathy in low-income and middle-income countries.

5 Aug, 2021 | 08:43h | UTC

Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh – The Lancet Global Health

News release: Brain injury treatment may cause harm in low and middle income nations – Imperial College London

Commentary: Hypoxic ischaemic encephalopathy in low resource settings—time to stop cooling? – The Lancet Global Health

 


Cohort study: Neurological manifestations of SARS-CoV-2 infection in hospitalized children and adolescents in the UK – “around 1 in 20 of children hospitalized with COVID-19 develop brain or nerve complications linked to the viral infection”.

26 Jul, 2021 | 02:58h | UTC

Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study – The Lancet Child & Adolescent Health

Commentaries:

Neuroinflammation triggered by SARS-CoV-2 infection: syndromes and therapies – The Lancet Child & Adolescent Health

New UK study reveals extent of brain complications in children hospitalized with COVID-19 – University of Liverpool

 

Commentary on Twitter

 


Systematic review: Prophylactic drug management for febrile seizures in children.

9 Jul, 2021 | 09:51h | UTC

Prophylactic drug management for febrile seizures in children – Cochrane Library

Summary: Prophylactic drug management for febrile seizures in children

 


Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.

25 Jun, 2021 | 10:15h | UTC

Selected issues in sport-related concussion (SRC|mild traumatic brain injury) for the team physician: a consensus statement – British Journal of Sports Medicine

News release: Strict Rest Slows Recovery after Sports-Related Concussions – American College of Sports Medicine

 


M-A: Parenting interventions to promote early child development in the first three years of life.

3 Jun, 2021 | 10:37h | UTC

Parenting interventions to promote early child development in the first three years of life: A global systematic review and meta-analysis – PLOS Medicine

 


Study suggests it is safe to discontinue antiseizure medication for most neonates with acute symptomatic seizures prior to discharge from the hospital.

27 May, 2021 | 08:14h | UTC

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures – JAMA Neurology (free for a limited period)

Editorial: Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures—Primum non nocere – JAMA Neurology (free for a limited period)

Commentaries: Stopping Antiseizure Medication After Acute Symptomatic Neonatal Seizures Is Found to Be Safe – Neurology Today AND Babies with Seizures May Be Overmedicated – Michigan Medicine

 

Commentary on Twitter

 


Cohort study: Babies surviving Group B strep more likely to require special educational support.

21 May, 2021 | 08:27h | UTC

Babies surviving Group B strep more likely to require special educational support – London School of Hygiene & Tropical Medicine

Original study: Mortality, neurodevelopmental impairments, and economic outcomes after invasive group B streptococcal disease in early infancy in Denmark and the Netherlands: a national matched cohort study – The Lancet Child & Adolescent Health

 


M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

21 May, 2021 | 08:24h | UTC

Prevalence of Bacterial Meningitis Among Febrile Infants Aged 29-60 Days With Positive Urinalysis Results: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Systematic review: Cognitive behavioral therapy may improve outcomes for autism spectrum disorders.

21 May, 2021 | 08:21h | UTC

Cognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review – Pediatrics (link to abstract – $ for full-text)

 


Guideline: Early intervention for children aged 0 to 2 years with or at high risk of cerebral palsy.

19 May, 2021 | 08:35h | UTC

Early Intervention for Children Aged 0 to 2 Years With or at High Risk of Cerebral Palsy: International Clinical Practice Guideline Based on Systematic Reviews – JAMA Pediatrics (free for a limited period)

Editorial: Early Intervention in Cerebral Palsy and Beyond (free for a limited period)

 


NICE Guideline Update | Headaches in over 12s: diagnosis and management.

18 May, 2021 | 07:14h | UTC

Headaches in over 12s: diagnosis and management – National Institute for Health and Care Excellence

 


Population-based cohort study: Youngest children in class are more likely to be diagnosed with a learning disability

11 May, 2021 | 09:08h | UTC

Relative age and specific learning disorder diagnoses: A Finnish population‐based cohort study – JCCP Advances

Commentary: Youngest children in class are more likely to be diagnosed with a learning disability – University of Turku

 


Cohort study: Risk of developmental difficulties remains high among children born early

5 May, 2021 | 08:24h | UTC

Neurodevelopmental outcomes at age 5 among children born preterm: EPIPAGE-2 cohort study – The BMJ

News release: Risk of developmental difficulties remains high among children born early – The BMJ

 

Commentary on Twitter

 


M-A: A third of kids develop a mental health problem after concussion

4 May, 2021 | 08:35h | UTC

News Release: A third of kids develop a mental health problem after concussion – Murdoch Childrens Research Institute

Original Study: Mental health after paediatric concussion: a systematic review and meta-analysis – British Journal of Sports Medicine

 


Choosing Wisely: Five things clinicians and patients should question in Neurological Surgery in Children

28 Mar, 2021 | 22:04h | UTC

American Academy of Pediatrics – Section on Neurological Surgery – Choosing Wisely

Commentary: Choosing Wisely: 5 Things to Avoid in Pediatric Neurologic Surgery – NEJM Journal Watch

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

10 Mar, 2021 | 08:29h | UTC

Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome – JAMA Neurology

 

Commentary on Twitter

 


RCT: Among children with Myelomeningocele, long term results confirm the benefits of prenatal repair compared to standard postnatal repair

10 Feb, 2021 | 01:28h | UTC

Prenatal Repair and Physical Functioning Among Children With Myelomeningocele: A Secondary Analysis of a Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Editorial: Long-term Outcomes of Children After Fetal Surgery for Spina Bifida—Toward Sustainability – JAMA Pediatrics (free for a limited period)

Commentaries: Spina Bifida Repair: The Sooner the Better – Physician’s Weekly AND Prenatal Myelomeningocele Repair Tied to Better Function – HealthDay

 

Commentary on Twitter

 


WHO issues new guidelines on the management of chronic pain in children

29 Jan, 2021 | 01:37h | UTC

Guideline: Guidelines on the management of chronic pain in children – World Health Organization

 


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