Pediatrics – Allergy and Immunology
RCT | Maternal egg intake in early neonatal period does not impact infant egg allergy risk
2 Aug, 2023 | 13:47h | UTCSee also: Visual Abstract
An ESPGHAN position paper on the diagnosis, management and prevention of cow’s milk allergy
31 Jul, 2023 | 14:28h | UTC
Adrenaline auto-injector prescription for patients at risk of anaphylaxis: BSACI guidance for primary care
6 Jun, 2023 | 14:28h | UTC
RCT | Peanut patch therapy is effective in desensitizing young children with allergies, but raises risk of serious adverse events
15 May, 2023 | 13:10h | UTCPhase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In the phase 3 EPITOPE trial involving children 1 to 3 years of age with peanut allergy, epicutaneous immunotherapy by means of a peanut patch was superior to placebo in desensitizing children to peanut. https://t.co/USk6HBI9Qh#pediatrics
— NEJM (@NEJM) May 10, 2023
M-A | Timing of allergenic food introduction and risk of immunoglobulin E–mediated food allergy
11 Apr, 2023 | 14:32h | UTCNews Release: Earlier introduction of allergenic foods in children may prevent food allergies – Imperial College London
Commentary: Allergenic Food Introduction Led to Fewer Allergies, Higher Withdrawal Rate from Intervention – HCP Live
Related:
AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease
Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society
Commentary on Twitter
In this study, earlier introduction of multiple allergenic foods was associated with a reduced risk of food allergy but with significant rates of withdrawal from the intervention. https://t.co/lZFkQIH9q7
— JAMA Pediatrics (@JAMAPediatrics) March 27, 2023
Cohort Study | Associations between fetal or infancy pet exposure and food allergies
3 Apr, 2023 | 13:26h | UTC
Two phase 3 trials of lebrikizumab for moderate-to-severe atopic dermatitis
21 Mar, 2023 | 13:23h | UTCTwo Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Largest study to date of lebrikizumab supports its use for treatment of atopic dermatitis – George Washington University
Commentary: Lebrikizumab Effective for Adults, Teens With Atopic Dermatitis – HealthDay
Study | Public health policies should recommend introducing peanut products to infants at 4-6 months of age to prevent peanut allergy
20 Mar, 2023 | 13:33h | UTCCommentary: Expert reaction to research on giving peanut products to babies – Science Media Centre
Related study: Early Introduction of Allergenic Foods Can Prevent Food Allergies in High Risk Infants
Related Guidelines:
AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease
Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society
Commentary from the author on Twitter
Latest paper from #LEAPStudy is now published in @JACIonline. We have looked at what happens if peanut products are introduced into the infant diet at different ages across the whole population. https://t.co/zpOlrNHOSihttps://t.co/xDIgYjezyS
More details below. @GoAllergy 1/12 pic.twitter.com/jY5MvdJ2AZ— Graham Roberts (@ProfGRoberts) January 12, 2023
RCT | Methylprednisolone vs. immunoglobulins equally effective in PIMS temporally associated with SARS-CoV-2
8 Feb, 2023 | 12:42h | UTC
SR | Skin care interventions in infants for preventing eczema and food allergy.
12 Dec, 2022 | 12:23h | UTCSkin care interventions in infants for preventing eczema and food allergy – Cochrane Library
Summary: Skin care interventions for preventing eczema and food allergy – Cochrane Library
Commentary on Twitter
Read our newest review on skin care interventions in infants for preventing eczema and food allergy! https://t.co/o8HtBXRVM5 pic.twitter.com/BPzsjJZvTf
— Cochrane Skin (@CochraneSkin) November 15, 2022
RCT | Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis.
20 Sep, 2022 | 13:20h | UTCCommentary: Dupilumab Eases Atopic Dermatitis in Children Younger Than 6 Years – HealthDay
Systematic Review | Anti‐IL‐5 therapies for asthma.
14 Jul, 2022 | 12:40h | UTCAnti‐IL‐5 therapies for asthma – Cochrane Library
Review: Management of moderate-severe atopic dermatitis in pediatric age.
27 Jun, 2022 | 11:32h | UTC
EULAR/ACR points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases.
24 Jun, 2022 | 11:23h | UTC
RCT: Effectiveness and safety of lotion, cream, gel, and ointment emollients for childhood eczema.
15 Jun, 2022 | 11:20h | UTCNews Release: The right moisturiser for children with eczema is the one that they like to use, study finds – University of Nottingham
Commentary: Lotion, Cream, Gel, and Ointment Similarly Effective for Childhood Eczema – HealthDay
Commentary on Twitter
New: @bee_study led by @riddmj found no difference in effectiveness between the four main types of emollients —lotions, creams, gels, and ointments—for childhood #eczema
The right #moisturizer is the one that children will use. https://t.co/45N5A136Kx
— The Lancet Child & Adolescent Health (@LancetChildAdol) May 24, 2022
M-A: Reproducibility of food challenge to cow’s milk.
15 Jun, 2022 | 10:42h | UTC
Position Paper: Diagnostic therapeutic care pathway for pediatric food allergies and intolerances.
14 Jun, 2022 | 11:05h | UTC
Another study suggests the Omicron variant is associated with a reduced risk of Multisystem Inflammatory Syndrome in Children compared to previous SARS-CoV-2 variants.
10 Jun, 2022 | 12:38h | UTCRelated study: Severity and Incidence of Multisystem Inflammatory Syndrome in Children During 3 SARS-CoV-2 Pandemic Waves in Israel – JAMA AND Commentary: Kids’ COVID syndrome—MIS-C—less severe in Omicron – CIDRAP
Commentary on Twitter
Study found that the risk of multisystem inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection during the #Omicron wave substantially lower compared to previous #SARSCoV2 variants. https://t.co/GYrz9XA72Z
— JAMA Pediatrics (@JAMAPediatrics) June 8, 2022
Consensus on the diagnosis and treatment of cow’s milk protein allergy.
2 Jun, 2022 | 10:56h | UTC
Cohort Study: Most egg allergy and nearly one-third of peanut allergy resolves naturally by age 6 years.
27 May, 2022 | 11:46h | UTCThe natural history of peanut and egg allergy in children up to age 6 years in the HealthNuts population-based longitudinal study – The Journal of Allergy & Clinical Immunology (link to abstract – $ for full-text)
Joint consensus guidelines on the diagnosis and management of eosinophilic esophagitis in children and adults.
25 May, 2022 | 11:32h | UTC
Guideline: Contact dermatitis.
10 May, 2022 | 10:54h | UTCGerman S1 guideline: Contact dermatitis – Journal of the German Society of Dermatology
Analysis of an intervention for emergency medical services personnel to reduce epinephrine dosing errors in infants.
19 Apr, 2022 | 01:52h | UTC
Commentary on Twitter
In this QI study, an infant resuscitation simulation intervention using 1mL syringes to draw up epinephrine (vs dosing from prefilled 10mL syringes) was associated with increased appropriate epinephrine use & fewer dosage errors, in less time. https://t.co/M3ztB1LMDi
— JAMA Network Open (@JAMANetworkOpen) April 15, 2022
Cohort Study: Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection.
12 Apr, 2022 | 09:57h | UTCCommentary: Older Kids More Vulnerable to MIS-C: Study – HealthDay
Translating research into practice: What’s new in the 2021 EAACI food allergy prevention guidelines?
8 Apr, 2022 | 10:00h | UTCOriginal Guideline: EAACI guideline: Preventing the development of food allergy in infants and young children – Pediatric Allergy and Immunology
Related:
Study: Early Introduction of Allergenic Foods Can Prevent Food Allergies in High Risk Infants
AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease
Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society (free)
Short Review: Food Allergy Prevention with Early Food Introduction