Fertility/Reproductive Medicine
Cohort Study | Children conceived via assisted reproductive technologies are at increased risk of childhood cancers.
7 Sep, 2022 | 12:32h | UTCAssisted Reproductive Technology and Risk of Childhood Cancers – JAMA Network Open
Invited Commentary: Fertility Treatment and Childhood Cancer Risk – JAMA Network Open
Commentary on Twitter
Children born of assisted reproductive technology (ART) conception was associated with an increased risk of overall childhood cancers compared with those conceived naturally and those with subfertility and non-ART conception. #OpenAccess #Research https://t.co/HylUVE4gFg
— JAMA Network Open (@JAMANetworkOpen) August 31, 2022
Cohort Study | Fertility preservation procedures appear to be safe at the time of breast cancer diagnosis.
7 Sep, 2022 | 12:31h | UTCNews Release: Fertility preservation measures do not appear to increase the risk of breast cancer recurrence – Karolinska Institutet
Systematic Review | Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse.
2 Sep, 2022 | 13:08h | UTC
Commentary on Twitter
❓ What is the effectiveness and safety of luteal support for those trying to conceive by intrauterine insemination #IUI or by sexual intercourse?
New @CochraneCGF systematic review looks at the evidence from 25 RCTs involving 5,111 participants. https://t.co/jjsetCMo3E pic.twitter.com/tWNtGx8rdC— The Cochrane Library (@CochraneLibrary) September 2, 2022
Cohort Study | Association of assisted reproductive technology with offspring growth and adiposity from infancy to early adulthood.
1 Aug, 2022 | 11:54h | UTC
Commentary on Twitter
This cohort study found that differences in early growth and adiposity for people conceived via assisted reproductive technology (vs. naturally) were small and reduced with older age. @aelhak19 @DeborahLawlor2 https://t.co/hwdldN6yDf
— JAMA Network Open (@JAMANetworkOpen) July 26, 2022
Report | The first 5 years of uterus transplant in the US.
13 Jul, 2022 | 11:27h | UTCThe First 5 Years of Uterus Transplant in the US: A Report From the United States Uterus Transplant Consortium – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Good Outcomes From First 5 Years of Uterus Transplants, But Concerns Remain – U.S.News
Commentary on Twitter
A multi-center study found uterus transplantation in the United States to be a safe, effective therapy for women with uterine-factor infertility to have children. https://t.co/nNYgjdP0fA
— JAMA Surgery (@JAMASurgery) July 6, 2022
RCT | Intravenous immunoglobulin treatment in women with four or more recurrent pregnancy losses.
12 Jul, 2022 | 11:53h | UTC
Infertility, recurrent pregnancy loss, and risk of stroke: pooled analysis of individual patient data of 618 851 women.
27 Jun, 2022 | 11:59h | UTCNews Release: Infertility and pregnancy loss may increase women’s risk of stroke – BMJ Newsroom
Commentary on Twitter
Infertility and pregnancy loss are associated with an increased risk of non-fatal and fatal stroke in later life, finds study.
Early monitoring of women who have experienced miscarriage or stillbirth could lower the risk, the researchers suggest https://t.co/fYrNfpz6fC
— The BMJ (@bmj_latest) June 24, 2022
RCT: Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF.
21 Jun, 2022 | 10:32h | UTCRelated: Fresh versus frozen embryo transfers in assisted reproduction – Cochrane Library
[News release – not published yet] Women not being routinely informed that a common anesthetic may lessen contraception effectiveness, doctors warn.
9 Jun, 2022 | 11:31h | UTCCommentary: Women in UK ‘seldom’ told drug used in surgery can impede contraception – The Guardian
RCT: Efficacy of bariatric surgery in treating women with obesity and polycystic ovary syndrome.
3 Jun, 2022 | 11:05h | UTC
Systematic Review: Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology.
1 Jun, 2022 | 11:02h | UTC
Commentary on Twitter
Transferring fresh embryos at the blastocyst stage (day 5 to 6) may increase live births compared to transfer at cleavage stage (day 2 to 3). We are uncertain if blastocyst‐stage transfer increases multiple pregnancy or miscarriage @CochraneLibrary https://t.co/O5CrUPTpet pic.twitter.com/YNdrwCIkmt
— Cochrane Gynaecology & Fertility (@CochraneCGF) May 25, 2022
Cohort Study: Analysis of antiemetic use after initiation of hormone therapy.
27 May, 2022 | 11:21h | UTCAnalysis of Antiemetic Use After Initiation of Hormone Therapy – JAMA Network Open
M-A: Effectiveness and harms of contraceptive counseling and provision interventions for women.
26 May, 2022 | 10:23h | UTCEffectiveness and Harms of Contraceptive Counseling and Provision Interventions for Women: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Annals Video Summary: Effectiveness and Harms of Contraceptive Counseling and Provision Interventions for Women: A Systematic Review and Meta-analysis
Commentary: Contraceptive counseling, provision increases use, reduces unintended pregnancy – ACP Internist
Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilization: RCT and systematic review.
12 May, 2022 | 07:53h | UTCRelated:
Obesity and risk of female reproductive conditions: A Mendelian randomization study.
27 Apr, 2022 | 01:31h | UTCObesity and risk of female reproductive conditions: A Mendelian randomisation study – PLOS Medicine
News Release: Obesity may increase risk of some female reproductive disorders – PLOS
Cohort Study: Infertility in women linked to increased risk of heart failure with preserved ejection fraction.
20 Apr, 2022 | 09:44h | UTCInfertility and Risk of Heart Failure in the Women’s Health Initiative – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Podcast: Infertility and Risk of Heart Failure in the Women’s Health Initiative
Commentaries:
Infertility in Women Linked to Subsequent Risk of HFpEF – TCTMD
MGH study finds infertility associated with increased risk of heart failure – MedicalResearch
M-A: Risk of recurrence in women with venous thromboembolism related to estrogen-containing contraceptives.
6 Apr, 2022 | 10:55h | UTC
IVF add-ons: why you should be cautious of these expensive procedures if you’re trying to conceive.
1 Apr, 2022 | 08:44h | UTCRelated:
Randomized Trial: Acupuncture Not Effective for Improving the Likelihood of In Vitro Fertilization
Research: Transfer of Fresh versus Frozen Embryos in Ovulatory Women
Guidance on the need for contraception related to use of pharmaceuticals: providing information on the proper use of pharmaceuticals in patients with reproductive potential.
31 Mar, 2022 | 07:49h | UTC
Cohort Study: Preconception paternal use of metformin linked to increased risk of congenital problems in offspring.
29 Mar, 2022 | 10:04h | UTCPreconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Study shows whole-genome risk prediction of common diseases in human preimplantation embryos is feasible, leading to ethical concerns.
22 Mar, 2022 | 09:42h | UTCWhole-genome risk prediction of common diseases in human preimplantation embryos – Nature Medicine
Invited Commentaries:
Polygenic embryo testing: understated ethics, unclear utility – Nature Medicine
The uncertain science of preimplantation and prenatal genetic testing – Nature Medicine
Commentary on Twitter (thread – click for more)
Preimplantation genetic testing of human embryos is a rapidly advancing field, but scientists and ethicists are calling for caution.
We present 3 articles highlighting new research and expert commentary on this controversial topic.
THREAD 🧵— Nature Medicine (@NatureMedicine) March 21, 2022
RCT: A preconception lifestyle intervention for weight loss did not improve fertility rates among women with obesity and infertility.
15 Mar, 2022 | 08:34h | UTCCommentary: Weight loss doesn’t help pregnancy chances, study finds – University of Virginia Health System
Choosing Wisely Canada: Canadian fertility and andrology society’s list of top items physicians and patients should question in fertility medicine.
14 Mar, 2022 | 01:23h | UTCChoosing Wisely Canada: Canadian fertility and andrology society’s list of top items physicians and patients should question in fertility medicine – Archives of Gynecology and Obstetrics (if the link is paywalled, try this one)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Bioethics | The rupture of anonymity for sperm donors—a tangled web of conflicting rights.
14 Mar, 2022 | 00:49h | UTCThe rupture of anonymity for sperm donors—a tangled web of conflicting rights – The BMJ
Commentary on Twitter
Direct-to-consumer DNA testing has torn the veil separating social family and genetic heritage. This Opinion article examines how it has brought the rights of donor conceived people to information into conflict with donors’ right to privacyhttps://t.co/avX64dbnhb
— The BMJ (@bmj_latest) March 11, 2022
Survey: Despite insufficient evidence of benefit, many fertility specialists still perform endometrial scratching before in vitro fertilization.
9 Feb, 2022 | 08:19h | UTCCommentary: Too Many Fertility Specialists Still Use a Painful, Useless Procedure: Study – HealthDay
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