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Oncology - Gastrointestinal

Review: Hyperthermic intraperitoneal chemotherapy for ovarian and colorectal cancer

7 May, 2021 | 08:23h | UTC

Hyperthermic Intraperitoneal Chemotherapy for Ovarian and Colorectal Cancer: A Review – JAMA Oncology (free for a limited period)

 


Cohort study: Sugar-sweetened beverage intake in adulthood and adolescence linked to increased risk of early-onset colorectal cancer among women

7 May, 2021 | 08:22h | UTC

Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women – Gut

Commentaries: Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk – BMJ AND Expert reaction to study looking at sugary drinks intake and incidence of early-onset colorectal cancer among women – Science Media Centre

 


Review: Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer

30 Apr, 2021 | 08:31h | UTC

Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer – JCO Oncology Practice

 


M-A: Helicobacter pylori eradication therapy to prevent gastric cancer – H. pylori eradication may reduce the incidence of gastric cancer in healthy individuals in East Asian countries

27 Apr, 2021 | 09:21h | UTC

Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis (link to abstract – $ for full-text – free article here)

 


Guide to Enhanced Recovery for Cancer Patients Undergoing Liver Surgery

25 Apr, 2021 | 20:53h | UTC

Guide to Enhanced Recovery for Cancer Patients Undergoing Liver Surgery – Annals of Surgical Oncology

See also: Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations – World Journal of Surgery AND Enhanced Recovery After Surgery (ERAS) Society Guidelines

 


Systematic review: Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

23 Apr, 2021 | 08:17h | UTC

Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease – Cochrane Library

Summary: Abdominal ultrasound and alpha-foetoprotein for the diagnosis of hepatocellular carcinoma – Cochrane Library

 


RCT: An Enhanced Recovery After Surgery (ERAS) program in laparoscopic distal gastrectomy provided a faster recovery, a shorter postoperative hospitalization length, and lower medical costs without increasing complication and readmission rates

16 Apr, 2021 | 06:16h | UTC

Randomized Controlled Trial Comparing the Short-term Outcomes of Enhanced Recovery After Surgery and Conventional Care in Laparoscopic Distal Gastrectomy – Annals of Surgery

Related: Consensus guidelines for enhanced recovery after gastrectomy – British Journal of Surgery AND Current status of the “enhanced recovery after surgery” program in gastric cancer surgery – Annals of Gastroenterological Surgery

See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines

 


RCT: Low-dose aspirin safely suppresses the recurrence of colorectal polyps in patients with familial adenomatous polyposis

14 Apr, 2021 | 01:49h | UTC

Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management

14 Apr, 2021 | 01:27h | UTC

Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management – Abdominal Radiology

 


RCT: Celecoxib for 3 years added to standard adjuvant therapy does not improve disease-free survival among patients with stage III colon cancer

7 Apr, 2021 | 01:28h | UTC

Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Celecoxib for Stage III Colon Cancer – JAMA (free for a limited period)

 


M-A: Similar oncological outcomes with laparoscopic vs. open rectal cancer resections

5 Apr, 2021 | 00:43h | UTC

Oncological outcomes of laparoscopic versus open rectal cancer resections: meta-analysis of randomized clinical trials – British Journal of Surgery

 


RCT: Second-line FOLFOX chemotherapy vs. active symptom control for advanced biliary tract cancer

1 Apr, 2021 | 03:21h | UTC

Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial – The Lancet Oncology

Commentary: Treating patients with advanced biliary tract cancers: Changing tactics – Cancer Research UK

 


RCT: Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer

1 Apr, 2021 | 03:19h | UTC

Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 


RCT: No benefit from palliative radiotherapy after esophageal cancer stenting

18 Mar, 2021 | 08:52h | UTC

Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial – The Lancet Gastroenterology & Hepatology

 


Cohort study: Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

14 Mar, 2021 | 20:09h | UTC

Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer – JAMA Oncology (free for a limited period)

 

Commentary on Twitter

 


RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases

7 Mar, 2021 | 19:23h | UTC

Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial – Journal of Clinical Oncology

Original study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters

 

 


ACG Clinical Guidelines: Start colorectal cancer screening at 45

5 Mar, 2021 | 08:31h | UTC

ACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology

Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45

 


Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers

24 Feb, 2021 | 02:00h | UTC

Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers – News Medical

Original study: Gastroesophageal reflux disease: A risk factor for laryngeal squamous cell carcinoma and esophageal squamous cell carcinoma in the NIH‐AARP Diet and Health Study cohort – Cancer

 


Review: Diagnosis and treatment of metastatic colorectal cancer

19 Feb, 2021 | 02:07h | UTC

Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review – JAMA (free for a limited period)

 


M-A: Role of diet in colorectal cancer incidence

17 Feb, 2021 | 01:12h | UTC

Role of Diet in Colorectal Cancer Incidence: Umbrella Review of Meta-analyses of Prospective Observational Studies – JAMA Network Open

 


RCT: Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer

16 Feb, 2021 | 01:44h | UTC

Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer (RELARC): a randomised, controlled, phase 3, superiority trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Clinical Cancer Advances 2021: ASCO’s Report on Progress Against Cancer

7 Feb, 2021 | 20:45h | UTC

Clinical Cancer Advances 2021: ASCO’s Report on Progress Against Cancer – Journal of Clinical Oncology

Commentary: ASCO Names Molecular Profiling in GI Cancers as Advance of the Year – OncLive

 


Duration of adjuvant doublet chemotherapy (3 or 6 months) in patients with high-risk stage II colorectal cancer

3 Feb, 2021 | 01:10h | UTC

Duration of Adjuvant Doublet Chemotherapy (3 or 6 months) in Patients With High-Risk Stage II Colorectal Cancer – Journal of Clinical Oncology

Commentary: Adjuvant Doublet Chemotherapy for High-Risk Stage II Colorectal Cancer: 3- or 6- Month Duration? – The ASCO Post

 


Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy

3 Feb, 2021 | 01:20h | UTC

Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)

Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA

Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology

 


Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70

26 Jan, 2021 | 00:37h | UTC

Aspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)

Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly

 


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