Oncology - Gastrointestinal
Review: Hyperthermic intraperitoneal chemotherapy for ovarian and colorectal cancer
7 May, 2021 | 08:23h | UTCHyperthermic Intraperitoneal Chemotherapy for Ovarian and Colorectal Cancer: A Review – JAMA Oncology (free for a limited period)
Cohort study: Sugar-sweetened beverage intake in adulthood and adolescence linked to increased risk of early-onset colorectal cancer among women
7 May, 2021 | 08:22h | UTCCommentaries: Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk – BMJ AND Expert reaction to study looking at sugary drinks intake and incidence of early-onset colorectal cancer among women – Science Media Centre
Review: Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer
30 Apr, 2021 | 08:31h | UTC
M-A: Helicobacter pylori eradication therapy to prevent gastric cancer – H. pylori eradication may reduce the incidence of gastric cancer in healthy individuals in East Asian countries
27 Apr, 2021 | 09:21h | UTCHelicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis (link to abstract – $ for full-text – free article here)
Guide to Enhanced Recovery for Cancer Patients Undergoing Liver Surgery
25 Apr, 2021 | 20:53h | UTCSee also: Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations – World Journal of Surgery AND Enhanced Recovery After Surgery (ERAS) Society Guidelines
Systematic review: Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease
23 Apr, 2021 | 08:17h | UTC
RCT: An Enhanced Recovery After Surgery (ERAS) program in laparoscopic distal gastrectomy provided a faster recovery, a shorter postoperative hospitalization length, and lower medical costs without increasing complication and readmission rates
16 Apr, 2021 | 06:16h | UTCRelated: Consensus guidelines for enhanced recovery after gastrectomy – British Journal of Surgery AND Current status of the “enhanced recovery after surgery” program in gastric cancer surgery – Annals of Gastroenterological Surgery
See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines
RCT: Low-dose aspirin safely suppresses the recurrence of colorectal polyps in patients with familial adenomatous polyposis
14 Apr, 2021 | 01:49h | UTCChemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Ishikawa et al – Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a randomised, 2×2 factorial trialhttps://t.co/NJ4b77p591#gitwitter #FAP #crcsm
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) April 2, 2021
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
14 Apr, 2021 | 01:27h | UTC
RCT: Celecoxib for 3 years added to standard adjuvant therapy does not improve disease-free survival among patients with stage III colon cancer
7 Apr, 2021 | 01:28h | UTCEffect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Celecoxib for Stage III Colon Cancer – JAMA (free for a limited period)
M-A: Similar oncological outcomes with laparoscopic vs. open rectal cancer resections
5 Apr, 2021 | 00:43h | UTC
RCT: Second-line FOLFOX chemotherapy vs. active symptom control for advanced biliary tract cancer
1 Apr, 2021 | 03:21h | UTCCommentary: Treating patients with advanced biliary tract cancers: Changing tactics – Cancer Research UK
RCT: Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer
1 Apr, 2021 | 03:19h | UTCAdjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
RCT: No benefit from palliative radiotherapy after esophageal cancer stenting
18 Mar, 2021 | 08:52h | UTC
Cohort study: Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer
14 Mar, 2021 | 20:09h | UTCAssociation of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer – JAMA Oncology (free for a limited period)
Commentary on Twitter
Ablative RT to 98Gy biologically effective dose following multiagent induction therapy for locally advanced pancreatic cancer (LAPC) was safe & resulted in durable locoregional tumor control & favorable survival https://t.co/pLf52Tt6j0 #GICSM
— JAMA Oncology (@JAMAOnc) March 12, 2021
RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases
7 Mar, 2021 | 19:23h | UTCOriginal study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters
Primary tumor resection followed by chemotherapy in patients with metastatic colorectal cancer doesn't improve survival over chemotherapy alone https://t.co/iOYqjaABzi @JCOG_official #crcsm #JCO pic.twitter.com/RCj2OHEehH
— ASCO Publications (@ASCO_pubs) March 5, 2021
ACG Clinical Guidelines: Start colorectal cancer screening at 45
5 Mar, 2021 | 08:31h | UTCACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology
Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45
Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers
24 Feb, 2021 | 02:00h | UTC
Review: Diagnosis and treatment of metastatic colorectal cancer
19 Feb, 2021 | 02:07h | UTCDiagnosis and Treatment of Metastatic Colorectal Cancer: A Review – JAMA (free for a limited period)
M-A: Role of diet in colorectal cancer incidence
17 Feb, 2021 | 01:12h | UTC
RCT: Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer
16 Feb, 2021 | 01:44h | UTCShort-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer (RELARC): a randomised, controlled, phase 3, superiority trial – The Lancet Oncology (link to abstract – $ for full-text)
Clinical Cancer Advances 2021: ASCO’s Report on Progress Against Cancer
7 Feb, 2021 | 20:45h | UTCCommentary: ASCO Names Molecular Profiling in GI Cancers as Advance of the Year – OncLive
Duration of adjuvant doublet chemotherapy (3 or 6 months) in patients with high-risk stage II colorectal cancer
3 Feb, 2021 | 01:10h | UTC
Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy
3 Feb, 2021 | 01:20h | UTCRisk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)
Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA
Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70
26 Jan, 2021 | 00:37h | UTCAspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)
Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly