Gastrointestinal Surgery (All Articles)
RCT: Immediate oral refeeding in patients with mild and moderate acute pancreatitis.
22 Jul, 2021 | 10:32h | UTCImmediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial) – Annals of Surgery (link to abstract – $ for full-text)
SAGES guidelines for the surgical treatment of gastroesophageal reflux.
21 Jul, 2021 | 10:34h | UTCSAGES guidelines for the surgical treatment of gastroesophageal reflux (GERD) – Surgical Endoscopy
AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia.
16 Jul, 2021 | 10:46h | UTC
Commentary on Twitter
Out now in @AGA_CGH: AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia. Had great time working on this with @AasmaShaukatMD & @seth_crockett. Hope it's a useful reference! @AmerGastroAssn
https://t.co/UB5hFMq6hc pic.twitter.com/KwHeKjU2dk— Peter Liang, MD MPH (@petersliang) February 19, 2021
M-A: Non-steroidal anti-inflammatory drugs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis.
16 Jul, 2021 | 10:28h | UTCNon-steroidal anti-inflammatory drugs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Akshintala et al – NSAIDs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-ERCP #pancreatitis: a systematic review and network meta-analysishttps://t.co/2Sh8WhqZRD#GITwitter #endoscopy #ERCP pic.twitter.com/nvAKXyPv13
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 30, 2021
Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.
14 Jul, 2021 | 11:07h | UTCNews release: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet
Commentaries: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian AND Expert reaction to study of alcohol and cancer – Science Media Centre
Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.
13 Jul, 2021 | 09:33h | UTCA Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial – Annals of Surgery (link to abstract – $ for full-text)
Related: A Randomized trial comparing antibiotics with appendectomy for appendicitis AND Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin AND Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis AND Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis AND Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International
Commentary on Twitter
The debate continues!
Another RCT comparing antibiotics to surgery for uncomplicated appendicitis – COMMA trial from 🇮🇪
Recurrence within 1-year : 25% after AB
Superior quality of life at 3 and 12mo after surgery.https://t.co/Yv51qpxchb
— Ville Sallinen (@villesallinen) July 11, 2021
RCT: Long-term efficacy of neoadjuvant chemoradiotherapy plus surgery for the treatment of locally advanced esophageal squamous cell carcinoma.
13 Jul, 2021 | 09:20h | UTC
Commentary on Twitter
Long-term outcomes from the NEOCRTEC5010 demonstrated the survival benefit of neoadjuvant chemoradiotherapy followed by surgery compared with surgery alone for patients with locally advanced esophageal squamous cell carcinoma https://t.co/UBBEEAynsy
— JAMA Surgery (@JAMASurgery) June 29, 2021
Ranitidine absolved? FDA study finds Ranitidine does not convert to carcinogen NDMA, regardless of diet.
12 Jul, 2021 | 01:36h | UTCEditorial: Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation
Commentary: Ranitidine: FDA finds no evidence of elevated NDMA, regardless of diet
Commentaries on Twitter
Despite ranitidine (zantac) being pulled from market last year, a new study from the FDA did not find evidence that it increases concentrations of the carcinogenic metabolite people were worried about (i.e., it's probably safe). From @JAMA_current https://t.co/AdRic2GdXS
— Zack Williams (@QuantPsychiatry) June 28, 2021
In this crossover, randomized clinical trial, oral ranitidine did not significantly increase 24-hour urinary excretion of NDMA when administered with a noncured-meats diet or a cured-meats diet. https://t.co/EszRvfJOFJ
— JAMA (@JAMA_current) June 28, 2021
RCT: Another study shows that non-antibiotic outpatient treatment in mild acute diverticulitis is safe.
12 Jul, 2021 | 01:29h | UTCEfficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)
Related: State of the Art Review: Management of colonic diverticulitis AND Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum AND Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial – Clinical Gastroenterology and Hepatology AND Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis
Commentary on Twitter
Another (final?) nail in the coffin for antibiotics in uncomplicated diverticulitis? DINAMO study from Spain – Outpatient treatment with antibiotics versus symptomatic Tx.
No difference in hospitalization rate or revisits to ER.https://t.co/wOc3tBGfxr @AnnalsofSurgery
— Ville Sallinen (@villesallinen) July 9, 2021
WSES position paper: Diagnosis and management of small bowel obstruction in virgin abdomen.
6 Jul, 2021 | 10:07h | UTC
Single-center, open-label RCT: Stimulant and osmotic laxatives after colorectal surgery results in earlier recovery of gastrointestinal function and reduces the incidence of prolonged postoperative ileus, without effects in the duration of hospital day or 30-day postoperative complications.
5 Jul, 2021 | 01:26h | UTCImpact of STIMUlant and osmotic LAXatives (STIMULAX trial) on gastrointestinal recovery after colorectal surgery: randomized clinical trial – British Journal of Surgery (link to abstract – $ for full-text)
Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
1 Jul, 2021 | 09:44h | UTC
Commentary on Twitter
Now available in Annals of Oncology, the @myESMO clinical practice guidelines for the diagnosis, treatment and follow-up of anal cancer, a rare disease accounting for less than 1% of all cancers https://t.co/usnFsd00BJ pic.twitter.com/bI0v60j8Ft
— Annals of Oncology (@Annals_Oncology) June 30, 2021
Review: Imaging of inflammatory disease of the pancreas.
30 Jun, 2021 | 10:03h | UTCImaging of inflammatory disease of the pancreas – British Journal of Radiology
Systematic review: the evidence behind robot-assisted abdominopelvic surgery – “there is currently no clear advantage with existing robotic platforms, which are costly and increase operative duration”.
29 Jun, 2021 | 09:55h | UTCThe Evidence Behind Robot-Assisted Abdominopelvic Surgery: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Robotic Platforms Not Superior for Abdominopelvic Surgery – HealthDay
AASLD Guideline: Vascular liver disorders, portal vein thrombosis, and procedural bleeding in patients with liver disease.
28 Jun, 2021 | 09:33h | UTC
RCT: Doxycycline for 7 days superior to single-dose azithromycin for the treatment of rectal chlamydia infection.
25 Jun, 2021 | 10:19h | UTCAzithromycin or Doxycycline for Asymptomatic Rectal Chlamydia trachomatis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Doxycycline Superior to Azithromycin for Asymptomatic Rectal Chlamydia in Men – Physician’s Weekly
Commentary on Twitter
Doxycycline is 20% more efficacious than azithromycin for the treatment of rectal chlamydia. Check out the results of our RCT published today in @NEJM.
Azithromycin or Doxycycline for Asymptomatic Rectal Chlamydia trachomatis | NEJM https://t.co/qpjo8VTg8u
— Jane Hocking (@JHocking01) June 23, 2021
Evidence-based clinical practice guidelines for management of colorectal polyps.
25 Jun, 2021 | 10:11h | UTC
Recommendations for the management of incidental pancreatic findings in adults.
24 Jun, 2021 | 09:48h | UTCRelated: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions: 2017 Consensus Recommendations of the Korean Society of Abdominal Radiology – Korean Journal of Radiology AND Cohort Study: Incidence, Prevalence and 5-year Pancreatic-related Mortality of Pancreatic Cysts AND Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults AND Prevalence and outcomes of incidental imaging findings: umbrella review AND Incidental anarchy – The BMJ Opinion
RCT: Routine use of prophylactic postoperative continuous positive airway pressure (CPAP) does not prevent pneumonia, re-intubation, and death after major abdominal surgery.
21 Jun, 2021 | 08:32h | UTCPostoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label, randomised, phase 3 trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Published today in @LancetRespirMed is the final report of @prismtrial, an international multi-centre phase-3 randomised trial of routine postoperative CPAP to prevent pneumonia, re-intubation & death after major abdominal surgery https://t.co/e09pSTi2sa @rupert_pearse @QMULWHRI
— Tom Abbott (@_tomabbott) June 19, 2021
2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy.
14 Jun, 2021 | 08:36h | UTC
M-A: No difference in major postoperative complications or mortality with perioperative liberal vs. restrictive fluid strategies in major abdominal elective surgery.
14 Jun, 2021 | 08:30h | UTC
RCT: Single-day low-residue diet prior to colonoscopy demonstrates improved bowel preparation quality and patient tolerance over clear liquid diet
14 Jun, 2021 | 08:26h | UTC
Guideline: Diagnosis and management of acute lower gastrointestinal bleeding.
3 Jun, 2021 | 10:49h | UTC
AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease.
1 Jun, 2021 | 08:07h | UTCTechnical Review: AGA Technical Review on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease
Clinical Decision Support Tool / Algorithm: Medical Management of Adult Outpatients With Moderate to Severe Lunminal Crohn’s Disease
Commentary on Twitter
Here are the @AmerGastroAssn guidelines on the management of moderate-severe Crohn disease. #GITwitter #GI #gut #IBD https://t.co/VlT4xTUE8t pic.twitter.com/ayYlpVkkod
— John Damianos, M.D. (@john_damianosMD) May 28, 2021
Podcast | Bariatric Surgery for the Internist – Patient selection, perioperative management, and post-operative care.
25 May, 2021 | 08:37h | UTC#275 Bariatric Surgery for the Internist with Dr. Vivian Sanchez – The Curbsiders