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Preventive Cardiology

Review | Obesity and contraceptive use: impact on cardiovascular risk.

16 Sep, 2022 | 12:53h | UTC

Obesity and contraceptive use: impact on cardiovascular risk – ESC Heart Failure

News Release: Combined birth control pill linked with increased risk of blood clots in obese women – European Society of Cardiology

 


Cohort Study | Patients diagnosed with diabetes by oral glucose tolerance test without elevated HbA1c had similar cardiovascular and renal disease risks as those without diabetes.

15 Sep, 2022 | 13:12h | UTC

Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study – Circulation

Commentary: Patients diagnosed by OGTT without elevated HbA1c had similar CV, renal disease risks as those without diabetes – ACP Diabetes

 

Commentary on Twitter

 


Cohort Study | Risk factors for heart disease and stroke are largely similar in men and women globally.

14 Sep, 2022 | 13:18h | UTC

News Release: Risk factors for heart disease and stroke are largely similar in men and women globally, finds study – McMaster University

Original Study: Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

https://twitter.com/TheLancet/status/1569636002762817536

 


Cohort Study | Prospective associations of daily step counts and intensity with cancer and cardiovascular disease incidence and mortality and all-cause mortality.

14 Sep, 2022 | 13:17h | UTC

Prospective Associations of Daily Step Counts and Intensity With Cancer and Cardiovascular Disease Incidence and Mortality and All-Cause Mortality – JAMA Internal Medicine

Commentaries:

Higher Step Counts Equal Better CV Health: UK Biobank – TCTMD

Pace as important as 10,000 steps for health, finds new research – University of Sidney

How Many Steps a Day (and How Fast) to Lengthen Your Life? – HealthDay

 


Cohort study showed a possible link between artificial sweeteners and heart disease.

11 Sep, 2022 | 22:55h | UTC

News Release: Possible link between artificial sweeteners and heart disease – BMJ Newsroom

Original Study: Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort – The BMJ

 


Review/Perspective | European hypertension guideline downgrading of beta-blockers is not justified.

31 Aug, 2022 | 11:51h | UTC

Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified – Blood Pressure

 


#ESCCongress | Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomized, double-blind trials.

30 Aug, 2022 | 12:16h | UTC

Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials – The Lancet

News Release: Cardiovascular protection from statins greatly outweighs the risk of muscle symptoms – European Society of Cardiology

Commentary: Only Very Small Risk of Muscle Symptoms With Statins: CTT Collaboration – TCTMD

 


Consensus Statement | Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis.

30 Aug, 2022 | 12:10h | UTC

Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement – European Heart Journal

 

Commentary on Twitter

 


Salt substitutes vs. regular salt: a quick look.

30 Aug, 2022 | 12:02h | UTC

Salt substitutes vs. regular salt: a quick look – Evidently Cochrane

Original Study: Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Related:

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Commentary on Twitter

 


[News release – not published yet] #ESCCongres – RCT | Evening dosing of blood pressure medication not better than morning dosing.

29 Aug, 2022 | 12:30h | UTC

Evening dosing of blood pressure medication not better than morning dosing – European Society of Cardiology

Related Consensus Statement: Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related study (conflicting results): Bedtime Hypertension Treatment Improves Cardiovascular Risk Reduction in Randomized Trial

 


Bedtime dosing of antihypertensive medications: systematic review and consensus statement. – “use of bedtime drug dosing of antihypertensive drugs should not be routinely recommended”.

29 Aug, 2022 | 12:28h | UTC

Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related: Evening dosing of blood pressure medication not better than morning dosing – European Society of Cardiology

 


#ESCCongress – RCT | A large study with 46.611 individuals between 65 and 74 years of age found that a comprehensive cardiovascular screening program did not significantly reduce the incidence of death from any cause.

29 Aug, 2022 | 12:24h | UTC

Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Cardiovascular screening may reduce risk of death and cardiovascular disease – European Society of Cardiology

 

Commentary on Twitter

 


[News release – not published yet] #ESCCongress – RCT | Allopurinol does not improve cardiovascular outcomes in ischemic heart disease patients.

29 Aug, 2022 | 12:15h | UTC

Allopurinol does not improve cardiovascular outcomes in ischaemic heart disease patients – European Society of Cardiology

Commentary:

ALL-HEART: Gout Drug Allopurinol No Help in CV Prevention – TCTMD

No improvement with allopurinol for patients with ischemic heart disease: ALL-HEART – Cardiology Now

 


Review | Incremental value of polygenic risk scores in primary prevention of coronary heart disease.

26 Aug, 2022 | 13:26h | UTC

Incremental Value of Polygenic Risk Scores in Primary Prevention of Coronary Heart Disease: A Review – JAMA Internal Medicine (free for a limited period)

Related:

Cohort Study | Predictive utility of a validated polygenic risk score for long-term risk of coronary heart disease in young and middle-aged adults.

Cohort Study | Polygenic risk, midlife life’s simple 7, and lifetime risk of stroke.

AHA Scientific Statement | Polygenic risk scores for cardiovascular disease.

Cohort Study: A polygenic risk score may improve risk stratification of coronary artery disease.

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps.

Studies: Little Benefit from Polygenic Risk Score vs. Clinical Risk Score for Predicting Cardiovascular Risk

 


USPSTF Recommendation Statement | Statin use for the primary prevention of cardiovascular disease in adults.

24 Aug, 2022 | 14:21h | UTC

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement – JAMA

Editorials:

Statins for Primary Cardiovascular Disease Prevention: Time to Curb Our Enthusiasm – JAMA Internal Medicine

Statins and Primary Atherosclerotic Cardiovascular Disease Prevention—What We Know, Where We Need to Go, and Why Are We Not There Already? – JAMA Network Open

Evidence Report: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author Interview: USPSTF Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults – JAMA

Patient Page: Statins for the Prevention of Cardiovascular Disease – JAMA

Commentary: Latest statins guidance keeps more conservative approach to preventing first stroke or heart attack – CNN

 


Podcast | USPSTF Update: aspirin for primary prevention of cardiovascular disease.

24 Aug, 2022 | 14:05h | UTC

#347 USPSTF Update: Aspirin for Primary Prevention of CVD – The Curbsiders

Related Guideline: USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

 


RCT | Effectiveness of an intervention for reducing sitting time and improving health in office workers.

22 Aug, 2022 | 12:19h | UTC

Effectiveness of an intervention for reducing sitting time and improving health in office workers: three arm cluster randomised controlled trial – The BMJ

Editorial: The importance of sitting less and moving more – The BMJ

News Release: Standing desks alongside other measures cut office workers’ sitting time by an hour a day – BMJ Newsroom

Commentary: SMART Work and Life Intervention Reduces Sitting Time for Office Workers – HealthDay

 

Commentary on Twitter

 


Cross-Sectional Study | Hypertension common among poorest, least educated around the world.

22 Aug, 2022 | 12:14h | UTC

The Association of Socioeconomic Status With Hypertension in 76 Low- and Middle-Income Countries – Journal of the American College of Cardiology (link to abstract – $ for full-text)

News Release: Hypertension Common Among Poorest, Least Educated Around the World – American College of Cardiology

Editorial: Hypertension—A Silent Killer Without Global Bounds: What Next? – Journal of the American College of Cardiology

Commentary: Hypertension Common Among Poorest, Least Educated Globally – HealthDay

 

Commentary on Twitter

 


Modeling Study | Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030.

18 Aug, 2022 | 12:42h | UTC

Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study – BMJ Nutrition Prevention & Health

News Release: 1 g cut in daily salt intake could ward off nearly 9 million cases of stroke/heart disease in China – BMJ Newsroom

 


Perspective | Is there an optimal diet for primordial prevention of atherosclerosis?

17 Aug, 2022 | 14:23h | UTC

Is there an optimal diet for primordial prevention of atherosclerosis? – European Journal of Cardiology

 


Position Paper | Step-by-step diagnosis and management of the nocebo/drucebo effect in statin-associated muscle symptoms patients.

16 Aug, 2022 | 13:42h | UTC

Step-by-step diagnosis and management of the nocebo/drucebo effect in statin-associated muscle symptoms patients: a position paper from the International Lipid Expert Panel (ILEP) – Journal of Sarcopenia, Cachexia and Muscle

 


Guideline for use of GLP-1 receptor agonists and SGLT2 inhibitors for cardiorenal risk reduction in adults.

15 Aug, 2022 | 12:29h | UTC

2022 Canadian Cardiovascular Society Guideline for Use of GLP-1 Receptor Agonists and SGLT2 Inhibitors for Cardiorenal Risk Reduction in Adults – Canadian Journal of Cardiology

See related systematic review: The Effectiveness of Sodium-Glucose Cotransporter 2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists on Cardiorenal Outcomes: Systematic Review and Meta-analysis – Canadian Journal of Cardiology

 

Commentary on Twitter (thread – click for more)

https://mobile.twitter.com/CJCJournals/status/1557751107006472193

 


AHA Scientific Statement | Effects of objective and perceived social isolation on cardiovascular and brain health.

15 Aug, 2022 | 12:31h | UTC

Effects of Objective and Perceived Social Isolation on Cardiovascular and Brain Health: A Scientific Statement From the American Heart Association – Circulation

News Release: Social isolation and loneliness increase the risk of death from heart attack, stroke – American Heart Association

Commentaries:

Social Isolation, Loneliness and Cardiovascular Health: The Art of Listening! – American Heart Association

Loneliness Can Be a Real Heartbreaker, Cardiac Experts Warn – HealthDay

 


Clinical Practice Update | The detection, evaluation, and management of dyslipidemia in children and adolescents.

15 Aug, 2022 | 12:12h | UTC

The Detection, Evaluation, and Management of Dyslipidemia in Children and Adolescents: A Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Clinical Practice Update – Canadian Journal of Cardiology

 


Harmonization of American and European hypertension guidelines: comparisons, reflections, and recommendations.

12 Aug, 2022 | 15:19h | UTC

Harmonization of the American College of Cardiology/American Heart Association and European Society of Cardiology/European Society of Hypertension Blood Pressure/Hypertension Guidelines: Comparisons, Reflections, and Recommendations – European Heart Journal (also available at Circulation)

 


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