Internal Medicine
New 2020 AHA Guidelines for CPR and emergency cardiovascular care in adults and children
22 Oct, 2020 | 09:47h | UTCHighlights: 2020 AHA Guidelines Update for CPR and ECC
Executive Summary: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
Best practices in managing cardiac arrest in the emergency department during the COVID-19 pandemic
22 Oct, 2020 | 09:44h | UTC
Randomized trial: Tocilizumab does not improve outcomes for patients hospitalized with Covid-19
22 Oct, 2020 | 09:42h | UTCEfficacy of Tocilizumab in Patients Hospitalized with Covid-19 – New England Journal of Medicine
New calculator predicts risk of hospital admission and mortality from coronavirus 19 in adults
22 Oct, 2020 | 09:37h | UTCSee calculator: QCovid® risk calculator
Commentary on Twitter
A new "living" high quality prediction model for #COVID19 risk for hospitalization and mortality: top 20% risk accounted for 94% of deaths; https://t.co/aPXRM2pHCq calculatorhttps://t.co/gdd8b3j33K @bmj_latest
by @AshClift @JuliaHCox @OxPrimaryCare and colleagues pic.twitter.com/s8TrWWECb0— Eric Topol (@EricTopol) October 21, 2020
Meta-analysis: Dual antiplatelet therapy after percutaneous coronary intervention and drug-eluting stents
22 Oct, 2020 | 09:29h | UTC
ATS Conference coverage: Many patients prescribed home oxygen after an acute COPD exacerbation no longer meet the criteria two to three months later
22 Oct, 2020 | 09:25h | UTCBreathing easier from hospital to home – ACP Internist
Video consultations in primary and specialist care during the covid-19 pandemic and beyond
21 Oct, 2020 | 09:30h | UTCVideo consultations in primary and specialist care during the covid-19 pandemic and beyond – The BMJ
Studies offer little hope for Tocilizumab in treating COVID
21 Oct, 2020 | 09:27h | UTCStudies offer little hope for tocilizumab in treating COVID – CIDRAP
See studies: Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19 – JAMA Internal Medicine AND Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial – JAMA Internal Medicine AND Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia: A Randomized Clinical Trial – JAMA Internal Medicine
Commentary: expert reaction to three studies of Tocilizumab to treat COVID patients – Science Media Centre
Related study (preprint): Tocilizumab in Hospitalized Patients With COVID-19 Pneumonia – medRxiv
Studies point to big drop in COVID-19 death rates
21 Oct, 2020 | 09:23h | UTCStudies Point To Big Drop In COVID-19 Death Rates – NPR
Guidelines for care of adults with Down Syndrome
21 Oct, 2020 | 09:14h | UTCMedical Care of Adults With Down Syndrome: A Clinical Guideline – JAMA (free for a limited period)
Editorial: Guidelines for Care of Adults With Down Syndrome
Podcast: Approach to shortness of breath
21 Oct, 2020 | 09:06h | UTC
[Abstract Only] Study: Excess days in acute care provide a more comprehensive picture of hospital performance compared to 30-day readmission rates
21 Oct, 2020 | 09:04h | UTCEvaluation of Hospital Performance Using the Excess Days in Acute Care Measure in the Hospital Readmissions Reduction Program – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Excess Days in Acute Care Provide More Comprehensive Picture of Hospital Performance Compared to 30-day Readmission Rates – AboutHealthTransparency.org AND EDAC: A ’More Comprehensive Picture of Hospital Use’ – Physician’s Weekly
Herd immunity and implications for SARS-CoV-2 control
20 Oct, 2020 | 01:44h | UTCHerd Immunity and Implications for SARS-CoV-2 Control – JAMA
Author Interview: Can We Count on Herd Immunity to Control COVID-19? – JAMA
Patient Page: What Is Herd Immunity? – JAMA
Commentary on Twitter
Herd immunity is real. It may be inevitable given our poor handling of COVID-19 and nature of the virus.
But to *deliberately* shoot for natural herd immunity (ie, without a vaccine) makes no sense.
Via @SaadOmer3 @InciYildirim11 @thehowie @JAMA_current https://t.co/PwWc1wMMzE pic.twitter.com/Ybn7vHFnt8
— Nicholas A. Christakis (@NAChristakis) October 19, 2020
Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s?
20 Oct, 2020 | 01:38h | UTC
Commentary on Twitter
Side effect of #COVID19 surge: ignoring well established strategies
➡️ limit ABTs exposure vs resistances: MV/long #ICU stay
➡️ avoid toxicity: antivirals/antibiotics can have severe adverse effects/interactions
➡️ high mortality: improving outcome crucial https://t.co/FN3LtKKlsr pic.twitter.com/7KGbIOH3Uf— Intens Care Med (@yourICM) October 17, 2020
Meta-analysis: The association of D-dimers with mortality, intensive care unit admission or ARDS in patients hospitalized with COVID-19
20 Oct, 2020 | 01:37h | UTC
The household secondary attack rate of SARS-CoV-2: A rapid review
20 Oct, 2020 | 01:36h | UTCThe household secondary attack rate of SARS-CoV-2: A rapid review – Clinical Infectious Diseases
Commentary on Twitter
Household secondary attack rate (SAR) of #SARSCoV2 A rapid review https://t.co/u2YGZYB9Zt The overall pooled random-effects estimate of the household SAR was 17.1% (95% CI: 13.7-21.2%). Household SAR higher among older adult contacts and among contacts of symptomatic cases.
— Carlos del Rio (@CarlosdelRio7) October 16, 2020
AHA Scientific Statement: Contemporary diagnosis and management of rheumatic heart disease
20 Oct, 2020 | 01:34h | UTCTop Things to Know: Contemporary Diagnosis and Management of Rheumatic Heart Disease – American Heart Association
KDIGO 2020 Clinical practice guideline for diabetes management in chronic kidney disease
20 Oct, 2020 | 01:33h | UTCExecutive summary: 2020 KDIGO Diabetes Management in CKD Guideline: evidence-based advances in monitoring and treatment – Kidney International
Commentary on Twitter
2020 #KDIGO Diabetes Management in #CKD Guidelinehttps://t.co/G127PgO1fe@deboerih @P_Rossing @goKDIGO pic.twitter.com/3kVNDpAoub
— Kidney International (@Kidney_Int) October 4, 2020
Plastic surgery complications: A review for emergency clinicians
20 Oct, 2020 | 01:32h | UTC
Cohort study: Exposure to modafinil and armodafinil during pregnancy linked to fetal malformations
20 Oct, 2020 | 01:31h | UTCPregnancy and Fetal Outcomes Following Exposure to Modafinil and Armodafinil During Pregnancy – JAMA Internal Medicine (free for a limited period)
Commentaries: Caution in Prescribing Modafinil and Armodafinil to Individuals Who Could Become Pregnant – JAMA Internal Medicine (free for a limited period) AND Narcolepsy Drugs Tied to Increased Risk for Birth Defects – NEJM Journal Watch
[Abstract Only] Systematic review and meta-analysis of native kidney biopsy complications
20 Oct, 2020 | 01:26h | UTCSystematic Review and Meta-Analysis of Native Kidney Biopsy Complications – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
A meta-analysis found that although native kidney biopsy is an invasive diagnostic procedure, the rates of bleeding complications are low. Complications are more frequently seen after kidney biopsies of hospitalized patients with AKI. https://t.co/kxK6qxX1fc pic.twitter.com/SgCoI505cc
— CJASN (@CJASN) October 15, 2020
[Abstract Only] Meta-analysis: Effect of urate-lowering therapy on cardiovascular and kidney outcomes
20 Oct, 2020 | 01:22h | UTCEffect of Urate-Lowering Therapy on Cardiovascular and Kidney Outcomes: A Systematic Review and Meta-Analysis – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
Study found urate-lowering therapy didn't produce benefits on clinical outcomes including major adverse cardiovascular events, all-cause mortality & kidney failure. Insufficient evidence to support urate lowering to improve kidney & cardiovascular outcomes https://t.co/uifm4vikYe pic.twitter.com/3fV60V3Lcx
— CJASN (@CJASN) October 14, 2020
Meta-analysis: Evidence-based prevention of Alzheimer’s disease
20 Oct, 2020 | 01:21h | UTCCommentaries: Biggest risk factors identified to try and prevent Alzheimer’s disease – BMJ AND Systematic review finds ten lifestyle factors that clearly impact the probability of developing Alzheimer’s disease (AD) – Sharp Brains
Commentary on Twitter
Evidence-based #prevention of #Alzheimers disease https://t.co/XOMiEoMlmI via @JNNP_BMJ #dementia @perryd43 @PennilessScribe @u3Y4BDE @SanWren @lfkraus @the_scholar1 @ktanimara @drsharwood @TargetLatino @LilithResists @Joseph_Santoro @liftdupbyangels @mrtom101 @SteveDitchfield pic.twitter.com/T5hqbzmIwi
— Ian Kremer (@LEAD_Coalition) July 24, 2020
WHO: Herd immunity, lockdowns and COVID-19
18 Oct, 2020 | 23:19h | UTCCoronavirus disease (COVID-19): Herd immunity, lockdowns and COVID-19 – World Health Organization
Commentary on Twitter
Herd immunity is a concept used for vaccination, in which a population can be protected from a virus if a threshold of vaccination is reached. Vaccinated people are protected from getting the disease & passing it on, breaking any chains of transmission.
👉https://t.co/X9N7zcyfOX pic.twitter.com/V22iA6OqOq
— World Health Organization (WHO) (@WHO) October 16, 2020
[Preprint] Multi-organ impairment in low-risk individuals with long COVID
18 Oct, 2020 | 23:18h | UTCMulti-organ impairment in low-risk individuals with long COVID – medRxiv
Related study (preprint): Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services – medRxiv
Commentary on Twitter
"In a young, low-risk population with ongoing symptoms, almost 70% of individuals have impairment in 1 or more organs 4 months after initial symptoms of #SARSCoV2 infection" #LongCovid https://t.co/gPnDtacI1J by @amibanerjee1 and colleagues
via @ahandvanish<-🙏 pic.twitter.com/7mKEsQgq5l— Eric Topol (@EricTopol) October 17, 2020