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Internal Medicine

An update on refractory hypertension.

24 Jun, 2022 | 11:44h | UTC

An Update on Refractory Hypertension – Current Hypertension Reports

 

Is shorter always better? The pros and cons of treating Gram-negative bloodstream infections with 7 days of antibiotics.

24 Jun, 2022 | 11:38h | UTC

Is shorter always better? The pros and cons of treating Gram-negative bloodstream infections with 7 days of antibiotics – JAC-Antimicrobial Resistance

 

Cohort Study: COVID-19 trajectories among 57 million adults in England.

24 Jun, 2022 | 11:34h | UTC

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records – The Lancet Digital Health

News Release: Most comprehensive analysis of COVID-19 data reveals previously unattributed deaths – Health Data Research UK

 

Commentary from one of the authors on Twitter (thread – click for more)

 

Position Paper: Teleconsultation in respiratory medicine.

24 Jun, 2022 | 11:11h | UTC

Teleconsultation in respiratory medicine – A position paper of the Portuguese Pulmonology Society – Pulmonology

 

Hemorrhagic fever with renal syndrome: literature review, epidemiology, clinical picture and pathogenesis.

24 Jun, 2022 | 11:02h | UTC

Hemorrhagic Fever with Renal Syndrome: Literature Review, Epidemiology, Clinical Picture and Pathogenesis – Infections & Chemotherapy

 

Retrospective Cohort Study: Prevalence and predictors of Pseudomonas aeruginosa among hospitalized patients with diabetic foot infections.

24 Jun, 2022 | 10:43h | UTC

Prevalence and Predictors of Pseudomonas aeruginosa among Hospitalized Patients with Diabetic Foot Infections – Open Forum Infectious Diseases

 

Commentary on Twitter

 

AHA Scientific Statement: Cardiopulmonary consequences of vaping in adolescents.

23 Jun, 2022 | 13:03h | UTC

Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association – Circulation Research

News Release: Action needed to reduce e-cigarette use among adolescents to lower lifetime CVD risk – American Heart Association

 

Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.

23 Jun, 2022 | 10:38h | UTC

News Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine

Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

 

We don’t know whether most medical treatments work, and we know even less about whether they cause harm – new study.

23 Jun, 2022 | 10:32h | UTC

We don’t know whether most medical treatments work, and we know even less about whether they cause harm – new study – The Conversation

Original Study: Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis – Journal of Clinical Epidemiology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

AGA Guidelines on the pharmacological management of irritable bowel syndrome.

23 Jun, 2022 | 10:24h | UTC

Part 1: Patients with diarrhea: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea – Gastroenterology

Part 2: Patients with constipation: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation – Gastroenterology

Commentary: AGA issues guidance on drug treatment for patients with IBS – ACP Gastroenterology

 

Commentary on Twitter

 

Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk.

23 Jun, 2022 | 10:22h | UTC

Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk – UK Medicines and Healthcare products Regulatory Agency

 

RCT: Weaning of maintenance immunosuppressive therapy in lupus nephritis.

23 Jun, 2022 | 10:18h | UTC

Weaning of maintenance immunosuppressive therapy in lupus nephritis (WIN-Lupus): results of a multicentre randomised controlled trial – Annals of Rheumatic Diseases

 

RCT: Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y Gastric bypass on weight loss, comorbidities, and reflux at 10 years in adult patients with obesity.

23 Jun, 2022 | 10:17h | UTC

Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With Obesity: The SLEEVEPASS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

 

M-A: Early versus delayed complete revascularization in patients presenting with ST-segment elevation myocardial infarction and multivessel disease.

23 Jun, 2022 | 10:11h | UTC

Early versus delayed complete revascularisation in patients presenting with ST-segment elevation myocardial infarction and multivessel disease: a systematic review and meta-analysis of randomised controlled trials – openheart

 

M-A: Intravenous iron vs. oral iron vs. no iron with or without erythropoiesis‐ stimulating agents for cancer patients with anemia.

23 Jun, 2022 | 10:10h | UTC

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer patients with anaemia: a systematic review and network meta‐analysis – Cochrane Library

Summary: Which combinations of medicines are best for the prevention and treatment of anaemia in people with cancer? – Cochrane Library

 

M-A: Effectiveness of pharmacological-based interventions, including education and prescribing strategies, to reduce subacute pain after total hip or knee arthroplasty.

23 Jun, 2022 | 10:04h | UTC

Effectiveness of Pharmacological-Based Interventions, Including Education and Prescribing Strategies, to Reduce Subacute Pain After Total Hip or Knee Arthroplasty: A Systematic Review of Randomized Controlled Trials – Pain Medicine

Commentary: Multimodal Analgesia and Education Reduces Postoperative Arthroplasty Pain, Opioid Consumption – Rheumatology Advisor

 

Commentary on Twitter

 

Study Commentary: Simple tool identifies the people with diabetes most likely to develop foot ulcers.

23 Jun, 2022 | 10:00h | UTC

Commentary: Simple tool identifies the people with diabetes most likely to develop foot ulcers – National Institute for Health and Care Research

Original Study: Development and validation of a clinical prediction rule for development of diabetic foot ulceration: an analysis of data from five cohort studies – BMJ Open Diabetes Research & Care

 

USPSTF Statement: The current evidence is insufficient to recommend vitamins for the prevention of cardiovascular disease or cancer.

22 Jun, 2022 | 12:21h | UTC

Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement – JAMA

Evidence Report and Systematic Review: Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and Cancer – JAMA

Patient Page: Vitamins and Minerals to Prevent Cardiovascular Disease and Cancer – JAMA

Editorial: Why Too Many Vitamins Feels Just About Right – JAMA Internal Medicine

Author Interview: Why Too Many Vitamins Feels Just About Right – JAMA

Commentary: Vitamins, Supplements Useless for Most People: Expert Panel – HealthDay

 

ASA and APSF statement on perioperative testing for the COVID-19 virus.

22 Jun, 2022 | 12:19h | UTC

ASA and APSF Statement on Perioperative Testing for the COVID-19 Virus – American Society of Anesthesiologists

Commentary: ASA, APST Update Perioperative SARS-CoV-2 Testing Recommendations – HealthDay

Related:

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 

Cohort Study: Successful 10-second one-legged stance performance predicts survival in middle-aged and older individuals.

22 Jun, 2022 | 12:18h | UTC

Successful 10-second one-legged stance performance predicts survival in middle-aged and older individuals – British Journal of Sports Medicine

News Release: Inability to stand on one leg in mid to later life linked to higher risk of death – University fo Bristol

 

Commentary on Twitter

 

Self-care management of bothersome symptoms as recommended by clinicians for patients with a chronic condition: A Delphi study.

22 Jun, 2022 | 12:13h | UTC

Self-care management of bothersome symptoms as recommended by clinicians for patients with a chronic condition: A Delphi study – Heart & Lung

 

Cohort Study: Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA.

22 Jun, 2022 | 12:07h | UTC

Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA: a cohort study in claims databases – The Lancet

Commentaries:

COVID-19 mRNA vaccination and myocarditis or pericarditis – The Lancet

Myocarditis and Pericarditis After the COVID-19 mRNA Vaccination – American College of Cardiology

Related:

SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents – JAMA Cardiology

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Review: Sex differences in sequelae from COVID-19 infection and in long COVID syndrome.

22 Jun, 2022 | 12:06h | UTC

Sex differences in sequelae from COVID-19 infection and in long COVID syndrome: a review – Current Medical Research and Opinion

Commentary: Women more likely to have long COVID, different symptom profile – CIDRAP

 

Position Paper: Diagnosis and management of infections caused by multidrug-resistant bacteria.

22 Jun, 2022 | 11:23h | UTC

A position paper for the diagnosis and management of infections caused by multidrug-resistant bacteria: Endorsed by the Italian Society of Infection and Tropical Diseases (SIMIT), the Italian Society of Anti-Infective Therapy (SITA), the Italian Group for Antimicrobial Stewardship (GISA), the Italian Association of Clinical Microbiologists (AMCLI), and the Italian Society of Microbiology (SIM) – International Journal of Antimicrobial Agents

Related Guideline:

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections: Version 2.0 – Infectious Diseases Society of America

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections: Version 1.0 – Infectious Diseases Society of America

 

Cohort Study: Association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease.

22 Jun, 2022 | 11:18h | UTC

The association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease in the UK Biobank – European Journal of Preventive Cardiology

 

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