Pediatrics – Neonatal/Perinatal
RCT: Dextrose gel for neonates at risk with asymptomatic hypoglycemia.
24 Jun, 2022 | 10:50h | UTCDextrose Gel for Neonates at Risk With Asymptomatic Hypoglycemia: A Randomized Clinical Trial – Pediatrics (link to abstract – $ for full-text)
Commentary on Twitter
New study in @aap_peds further adds to evidence on use of Dextrose gel – It reduces the need for intravenous fluids in at-risk neonates with asymptomatic hypoglycemia in the first 48 hours of life in this stratified RCT.https://t.co/5EsIHOFJc1 #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/27VKzeIIat
— Evidence-Based Neo (@EBNEO) May 20, 2022
Sleep-Related Infant Deaths: Updated AAP 2022 recommendations for reducing infant deaths in the sleep environment.
23 Jun, 2022 | 13:05h | UTCCommentaries:
New safe-sleep guidelines aim to reduce infant deaths – University of Virginia Health System
AAP Updates Recommendations for Safe Infant Sleep Practices – HealthDay
Commentary on Twitter
Each year in the US approximately 3,500 infants die from sleep-related infant deaths. The @AmerAcadPeds recommends a safe sleep environment to reduce the risk of all sleep-related deaths. This Policy Statement provides updated guidance: https://t.co/y3RxNffsEv #Pediatrics pic.twitter.com/WFCKPJFdPd
— AAP Pediatrics (@aap_peds) June 22, 2022
Cohort Study: Neurodevelopmental outcomes at 1 year in infants of mothers who tested positive for SARS-CoV-2 during pregnancy.
10 Jun, 2022 | 12:14h | UTCCommentaries:
Commentary on Twitter
This cohort study of #SARSCoV2 exposure in utero found preliminary evidence that maternal SARS-CoV-2 may be associated with neurodevelopmental sequelae in some offspring. https://t.co/dYdoJbNOdl
— JAMA Network Open (@JAMANetworkOpen) June 9, 2022
Cohort Study: Association of SARS-CoV-2 infection during pregnancy with maternal and perinatal outcomes.
3 Jun, 2022 | 11:55h | UTCAssociation of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes – JAMA
Guideline: Ultrasound in labor.
3 Jun, 2022 | 11:34h | UTC
Essential components of postnatal care – a systematic literature review and development of signal functions to guide monitoring and evaluation.
2 Jun, 2022 | 10:29h | UTC
Global, regional, and national incidence and mortality of neonatal preterm birth, 1990-2019.
1 Jun, 2022 | 11:15h | UTCCommentary: Global Incidence of Neonatal Preterm Birth Decreasing Overall – HealthDay
Commentary on Twitter
Data from the Global Burden of Disease study found preterm birth remains a crucial issue in children worldwide and discovery research into the underlying mechanisms of neonatal preterm birth and the development of innovative interventions are urgent. https://t.co/ajOK4FUlHf
— JAMA Pediatrics (@JAMAPediatrics) May 31, 2022
Recommendations during shortage of artificial breast milk substitutes.
30 May, 2022 | 11:31h | UTC
M-A: Gestational diabetes mellitus and adverse pregnancy outcomes.
27 May, 2022 | 12:25h | UTC
Commentary on Twitter
NEW research finds gestational diabetes is associated with increased odds of a range of complications for both mother and baby, including caesarean delivery, severe breathing problems, and excessive birth weight https://t.co/oyzkFxMslc
— The BMJ (@bmj_latest) May 26, 2022
Cohort Study: Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes.
27 May, 2022 | 12:22h | UTCNews Release: Painkiller advice for pregnant women should always be followed, as use is linked to newborn problems – University of Aberdeen
Related:
Paracetamol use during pregnancy — a call for precautionary action – Nature Reviews Endocrinology
Editorial: Caution needed: paracetamol use in pregnancy – Nature Reviews Endocrinology
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019.
27 May, 2022 | 12:15h | UTCCommentaries:
Need for improved global measurement of early childhood respiratory syncytial virus disease – The Lancet (free registration required)
RSV kills 100,000 kids under age 5 a year worldwide – CHEST Physician
Interventions for the prevention of spontaneous preterm birth: a scoping review of systematic reviews.
27 May, 2022 | 11:19h | UTC
Systematic Review: The effects of breastfeeding on maternal mental health.
18 May, 2022 | 10:29h | UTC
Group B streptococcus infection during pregnancy and infancy: estimates of regional and global burden.
12 May, 2022 | 10:03h | UTCInvited Commentary: Variation of invasive neonatal GBS disease across the regions – The Lancet Global Health
Commentary on Twitter
Group B #streptococcus (GBS) colonisation during #pregnancy can lead to invasive GBS disease (iGBS) in #infants, including #meningitis or sepsis with a high mortality risk. There is a higher burden of iGBS than previously estimatedhttps://t.co/jr8zNS7Lak@LancetGH pic.twitter.com/XBsImwD13H
— The Lancet Reg Health-Southeast Asia (@LancetRH_SEAsia) May 5, 2022
Evidence for Maternity Care: new evidence and resources.
11 May, 2022 | 11:03h | UTCEvidence for Maternity Care: new evidence and resources – May 2022 – Evidently Cochrane
Review: Current status and future directions of neuromonitoring with emerging technologies in neonatal care.
5 May, 2022 | 09:47h | UTC
M-A: Interventions to prevent bronchopulmonary dysplasia in preterm neonates.
5 May, 2022 | 09:44h | UTCInterventions to Prevent Bronchopulmonary Dysplasia in Preterm Neonates: An Umbrella Review of Systematic Reviews and Meta-analyses – JAMA Pediatrics (link to abstract – $ for full-text)
Related:
State of the Art Review: Diagnosis and management of bronchopulmonary dysplasia.
ERS Guideline on Long-term Management of Children with Bronchopulmonary Dysplasia
Research: Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia
Commentary on Twitter
A meta-analysis in @JAMAPeds evaluates interventions that may prevent BPD https://t.co/871W5OaNAC #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/UXfYhQU3wd
— Evidence-Based Neo (@EBNEO) March 9, 2022
RCT: Effects of prophylactic oral dextrose gel on neurosensory impairment at 2-year follow-up in late preterm and term infants born at risk of neonatal hypoglycemia.
4 May, 2022 | 10:43h | UTCProphylactic Oral Dextrose Gel and Neurosensory Impairment at 2-Year Follow-up of Participants in the hPOD Randomized Trial – JAMA (link to abstract – $ for full-text)
Commentary: New insight into protecting newborns with low blood sugars – University of Auckland
Related:
Cohort Study: No association of neonatal hypoglycemia with academic performance in mid-childhood.
Oral dextrose gel for the treatment of hypoglycemia in newborn infants.
Commentary on Twitter
@EdwardsTaygen et al present 2-year Neurosensory Follow-Up results from their multicenter, double-blinded, placebo controlled hPOD randomized trial @JAMA_current https://t.co/ik6AKIjahS #EBNEOalerts, #neotwitter, #neoEBM pic.twitter.com/dQH8qti5Fv
— Evidence-Based Neo (@EBNEO) March 25, 2022
M-A: Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy.
1 May, 2022 | 23:09h | UTC
WHO reveals shocking extent of exploitative formula milk marketing.
29 Apr, 2022 | 10:58h | UTCNews Release: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization
Commentary on Twitter (thread – click for more)
🆕 WHO report reveals shocking extent of exploitative formula milk marketing
The formula milk industry, valued at US$55 billion, is paying social media platforms & influencers to gain direct access to pregnant women & mothers.#EndExploitativeMarketing
👉https://t.co/0dciNxB0fQ pic.twitter.com/hhAnyp0ueH— World Health Organization (WHO) (@WHO) April 29, 2022
RCT: Nasal high-flow therapy during neonatal endotracheal intubation.
28 Apr, 2022 | 08:07h | UTCNasal High-Flow Therapy during Neonatal Endotracheal Intubation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Successful Intubations Up With Nasal High-Flow Therapy in Neonates – HealthDay
Commentary on Twitter
Nasal high-flow therapy during neonatal endotracheal intubation increased the likelihood of successful intubation on the first attempt without physiological instability. https://t.co/JWRgtAcoAN pic.twitter.com/EQdFW6pojF
— NEJM (@NEJM) April 27, 2022
Phase 2b trial: Prefusion F protein–based respiratory syncytial virus immunization in pregnancy.
28 Apr, 2022 | 08:09h | UTCPrefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: RSV Prefusion F Protein-Based Immunization Studied in Pregnancy – HealthDay
Commentary on Twitter
In pregnant women, RSVpreF vaccine elicited neutralizing antibody responses with efficient transplacental transfer and without evident safety concerns. https://t.co/r8oktZmBZQ pic.twitter.com/UE7ffxYJW6
— NEJM (@NEJM) April 27, 2022
RCT: Noninvasive high-frequency oscillatory ventilation vs. nasal continuous positive airway pressure vs. nasal intermittent positive pressure ventilation as postextubation support for preterm neonates.
27 Apr, 2022 | 07:59h | UTCNoninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentaries on Twitter
In this randomized clinical trial, NHFOV and nasal intermittent positive pressure ventilation in neonates provided a small advantage of reduced need for invasive respiratory support when used from extubation and until discharge. https://t.co/qCtNP8Gwj9
— JAMA Pediatrics (@JAMAPediatrics) April 25, 2022
A RCT in @JAMAPediatrics evaluates total duration of mechanical ventilation, need for reintubation, and ventilator-free days after extubation to either NHFOV, NCPAP or NIPPV. https://t.co/krwwMv2Hbr#EBNEOalerts #neoEBM #neotwitter pic.twitter.com/uenwdlZfO4
— Evidence-Based Neo (@EBNEO) April 27, 2022
UK drug regulator advises patients and doctors against the use of Pregabalin during pregnancy due to a possible increased risk of congenital malformations.
22 Apr, 2022 | 09:31h | UTCSee also: Pregabalin and risks in pregnancy – Medicines and Healthcare products Regulatory Agency
Source: Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator – The BMJ ($)
Commentary on Twitter
The Medicines and Healthcare Products Regulatory Agency (@MHRAgovuk) has strengthened its warning about avoiding pregabalin during pregnancy after new data showed an increased risk of major congenital malformations associated with the drug https://t.co/ghGvqCqA0C
— The BMJ (@bmj_latest) April 22, 2022
M-A: Invasive group A streptococcal disease in pregnant women and young children.
20 Apr, 2022 | 09:05h | UTCInvited Commentary: Recognising group A streptococcal disease in pregnancy – The Lancet Infectious Diseases (free registration required)