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Pediatrics - Neonatal-Perinatal

RCT showed improved outcomes with fetal surgery for severe left diaphragmatic hernia.

5 Jul, 2021 | 01:53h | UTC

Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia – New England Journal of Medicine (link to abstract – $ for full-text – Full text can be found here)

Commentary: Fetal Surgery Boosts Survival for Babies With Severe Birth Defect – MedPage Today (free registration required)

 


Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic enabled the reduction of in-person consultations by 50% without compromising pregnancy outcomes.

2 Jul, 2021 | 11:26h | UTC

Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic: an interrupted time-series analysis – The Lancet

Commentary: Expanding the concept of safety in antenatal care provision – The Lancet

 


WHO: Caesarean section rates continue to rise, amid growing inequalities in access.

18 Jun, 2021 | 08:23h | UTC

Caesarean section rates continue to rise, amid growing inequalities in access – World Health Organization

Original study: Trends and projections of caesarean section rates: global and regional estimates – BMJ Global Health

 

Commentary on Twitter (thread – click for more)

 


M-A: Delivery room interventions for hypothermia in preterm neonates – “use of a plastic bag or wrap with a plastic cap or with heated humidified gas was associated with lower risk of major brain injury and mortality”.

1 Jun, 2021 | 08:10h | UTC

Delivery Room Interventions for Hypothermia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)

 


RCT: Immediate “kangaroo mother care” improves survival in infants with low birth weight compared to conventional care with “kangaroo mother care” initiated after stabilization.

27 May, 2021 | 08:18h | UTC

Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight – New England Journal of Medicine

Commentary: Immediate skin-to-skin contact after birth improves survival of pre-term babies – Karolisnka Institutet

Related: RCT: Community-initiated kangaroo mother care reduced the risk of moderate-to-severe maternal postpartum depressive symptoms among mothers of low-birth-weight infants in low-income areas in India AND WHO: New research highlights risks of separating newborns from mothers during COVID-19 pandemic AND Randomized Trial: Kangaroo Mother Care Improves Survival of Infants with Low Birthweight

 


Study suggests it is safe to discontinue antiseizure medication for most neonates with acute symptomatic seizures prior to discharge from the hospital.

27 May, 2021 | 08:14h | UTC

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures – JAMA Neurology (free for a limited period)

Editorial: Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures—Primum non nocere – JAMA Neurology (free for a limited period)

Commentaries: Stopping Antiseizure Medication After Acute Symptomatic Neonatal Seizures Is Found to Be Safe – Neurology Today AND Babies with Seizures May Be Overmedicated – Michigan Medicine

 

Commentary on Twitter

 


Systematic Review: Oral dextrose gel reduces the risk of neonatal hypoglycemia in at‐risk infants and probably reduces the risk of major neurological disability at two years.

25 May, 2021 | 08:38h | UTC

Oral dextrose gel to prevent hypoglycaemia in at‐risk neonates – Cochrane Library

Summary: Oral dextrose gel for prevention of low blood glucose levels in newborn babies – Cochrane Library

 


Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.

19 May, 2021 | 08:20h | UTC

Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome – Cochrane Library

Summary: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome – Cochrane Library

 

Commentary on Twitter

 


WHO: New report sounds the alarm on global shortage of 900 000 midwives.

6 May, 2021 | 08:45h | UTC

New report sounds the alarm on global shortage of 900 000 midwives – World Health Organization

Report: The State of the World’s Midwifery 2021 – UN sexual and reproductive health agency

 

Commentary on Twitter (thread – click for more)

 


Cohort study: Risk of developmental difficulties remains high among children born early

5 May, 2021 | 08:24h | UTC

Neurodevelopmental outcomes at age 5 among children born preterm: EPIPAGE-2 cohort study – The BMJ

News release: Risk of developmental difficulties remains high among children born early – The BMJ

 

Commentary on Twitter

 


RCT: Community-initiated kangaroo mother care reduced the risk of moderate-to-severe maternal postpartum depressive symptoms among mothers of low-birth-weight infants in low-income areas in India

5 May, 2021 | 08:21h | UTC

Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress Among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


RCT: Discontinuing nasal continuous positive airway pressure either at 5 cm H2O vs. 3 cm H2O in infants ≤32 weeks of gestational age

3 May, 2021 | 05:15h | UTC

Discontinuing Nasal Continuous Positive Airway Pressure in Infants ≤32 Weeks of Gestational Age: A Randomized Control Trial – The Journal of Pediatrics (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Cohort study: Association of maternal SARS-CoV-2 infection in pregnancy with neonatal outcomes – “although babies born of test-positive mothers are more likely to be born early, extremely few were infected with COVID-19”

30 Apr, 2021 | 08:17h | UTC

Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes – JAMA

News release: Low risk of infection in babies born to mothers with COVID-19 – Karolinska Institutet

Editorial: Understanding Risk for Newborns Born to SARS-CoV-2–Positive Mothers – JAMA

 

Commentary on Twitter

 


Pre-post study: A hospital quality improvement intervention significantly reduced the rates of cesarean delivery for nulliparous, term, singleton, vertex births

29 Apr, 2021 | 08:21h | UTC

Hospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California – JAMA (free for a limited period)

Editorial: Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births – JAMA

 

Commentary on Twitter (thread – click for more)

 


Covid-19: More data on the increased risks to pregnant women and their newborn infants

23 Apr, 2021 | 08:44h | UTC

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study – JAMA Pediatrics

Editorial: COVID-19 in Pregnant Women and Their Newborn Infants

Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN

Related: Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

 

Commentary on Twitter

 


Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

22 Apr, 2021 | 08:49h | UTC

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons – New England Journal of Medicine

Audio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine

Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News

 


Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions

22 Apr, 2021 | 08:19h | UTC

Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions – Agency for Healthcare Research and Quality

See also: Final Report AND Evidence Summary

 


NICE Guideline | Neonatal infection: antibiotics for prevention and treatment

21 Apr, 2021 | 06:46h | UTC

Neonatal infection: antibiotics for prevention and treatment – National Institute for Health and Care Excellence

 


NICE Guideline | Postnatal care

21 Apr, 2021 | 06:43h | UTC

Postnatal care – National Institute for Health and Care Excellence

 


Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

2 Apr, 2021 | 09:23h | UTC

Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis – The Lancet Global Health

Commentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health

 

Commentary on Twitter

 


The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis

31 Mar, 2021 | 03:27h | UTC

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis – Canadian Medical Association Journal

 


Cohort study: Even small amounts of Caffeine consumption in pregnancy were linked to smaller neonatal birth size

28 Mar, 2021 | 22:14h | UTC

Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies–Singletons – JAMA Network Open

Commentaries: Even a Little Coffee in Pregnancy Could Impact Newborn’s Weight: Study – HealthDay AND Moderate daily caffeine intake during pregnancy may lead to smaller birth size – NIH News Releases

 

Commentary on Twitter

 


Systematic review: Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates

18 Mar, 2021 | 08:45h | UTC

Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates – Cochrane Library

 


WHO: New research highlights risks of separating newborns from mothers during COVID-19 pandemic

17 Mar, 2021 | 03:04h | UTC

New research highlights risks of separating newborns from mothers during COVID-19 pandemic – World Health Organization

Original study: Preterm care during the COVID-19 pandemic: A comparative risk analysis of neonatal deaths averted by kangaroo mother care versus mortality due to SARS-CoV-2 infection – EclinicalMedicine

 


M-A: Assessment of postnatal corticosteroids for the prevention of bronchopulmonary dysplasia in preterm neonates

16 Mar, 2021 | 01:38h | UTC

Assessment of Postnatal Corticosteroids for the Prevention of Bronchopulmonary Dysplasia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (free for a limited period)

Editorial: The Swinging Pendulum of Postnatal Corticosteroid Use (free for a limited period)

 


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