Pediatrics - Neonatal-Perinatal | Links Medicus Free Medical News & Perspectives

RCT showed improved outcomes with fetal surgery for severe left diaphragmatic hernia.

5 Jul, 2021 | 01:53h | UTC

Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia – New England Journal of Medicine (link to abstract – $ for full-text – Full text can be found here)

Commentary: Fetal Surgery Boosts Survival for Babies With Severe Birth Defect – MedPage Today (free registration required)

Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic enabled the reduction of in-person consultations by 50% without compromising pregnancy outcomes.

2 Jul, 2021 | 11:26h | UTC

Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic: an interrupted time-series analysis – The Lancet

Commentary: Expanding the concept of safety in antenatal care provision – The Lancet

WHO: Caesarean section rates continue to rise, amid growing inequalities in access.

18 Jun, 2021 | 08:23h | UTC

Caesarean section rates continue to rise, amid growing inequalities in access – World Health Organization

Original study: Trends and projections of caesarean section rates: global and regional estimates – BMJ Global Health

Commentary on Twitter (thread – click for more)

Caesarean section use continues to rise 📈 globally, now accounting for more than 1 in 5 of all childbirths.

C-section can put women and babies at unnecessary risk of short- and long-term health problems if performed when there is not medical need

https://t.co/tvfsQO1zMX

— World Health Organization (WHO) (@WHO) June 17, 2021

M-A: Delivery room interventions for hypothermia in preterm neonates – “use of a plastic bag or wrap with a plastic cap or with heated humidified gas was associated with lower risk of major brain injury and mortality”.

1 Jun, 2021 | 08:10h | UTC

Delivery Room Interventions for Hypothermia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)

RCT: Immediate “kangaroo mother care” improves survival in infants with low birth weight compared to conventional care with “kangaroo mother care” initiated after stabilization.

27 May, 2021 | 08:18h | UTC

Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight – New England Journal of Medicine

Commentary: Immediate skin-to-skin contact after birth improves survival of pre-term babies – Karolisnka Institutet

Study suggests it is safe to discontinue antiseizure medication for most neonates with acute symptomatic seizures prior to discharge from the hospital.

27 May, 2021 | 08:14h | UTC

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures – JAMA Neurology (free for a limited period)

Editorial: Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures—Primum non nocere – JAMA Neurology (free for a limited period)

Commentaries: Stopping Antiseizure Medication After Acute Symptomatic Neonatal Seizures Is Found to Be Safe – Neurology Today AND Babies with Seizures May Be Overmedicated – Michigan Medicine

Commentary on Twitter

New CER study on @JAMANeuro finds no difference in functional neurodevelopment or epilepsy at 24 mnths in children whose antiseizure meds was discont'd vs maintained at discharge after resolution of acute symptomatic neonatal seizures: https://t.co/yvKbrJuCvQ #ebneoalerts #neoEBM pic.twitter.com/810weSUSgb

— Evidence-Based Neo (@EBNEO) May 26, 2021

Systematic Review: Oral dextrose gel reduces the risk of neonatal hypoglycemia in at‐risk infants and probably reduces the risk of major neurological disability at two years.

25 May, 2021 | 08:38h | UTC

Oral dextrose gel to prevent hypoglycaemia in at‐risk neonates – Cochrane Library

Summary: Oral dextrose gel for prevention of low blood glucose levels in newborn babies – Cochrane Library

Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.

19 May, 2021 | 08:20h | UTC

Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome – Cochrane Library

Summary: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome – Cochrane Library

Commentary on Twitter

Is giving surfactant via minimally invasive technique involving placement of a thin catheter in the trachea of a spontaneously breathing #infant effective and safe? https://t.co/0TKceRx4Oh New #SystematicReview from @CochraneNeonate looks at the evidence from 6 randomised trials. pic.twitter.com/qPB3Q0vp9E

— Cochrane UK (@CochraneUK) May 15, 2021

WHO: New report sounds the alarm on global shortage of 900 000 midwives.

6 May, 2021 | 08:45h | UTC

New report sounds the alarm on global shortage of 900 000 midwives – World Health Organization

Report: The State of the World’s Midwifery 2021 – UN sexual and reproductive health agency

Commentary on Twitter (thread – click for more)

9⃣3⃣% of #midwives are women. But too many face persistent gender discrimination that prevents them from thriving professionally.

Gender transformative policies are key to change this! 👉https://t.co/qxkv16SVxp #MidwivesDay #IDM2021 pic.twitter.com/7aBBwvXFQa

— World Health Organization (WHO) (@WHO) May 5, 2021

Cohort study: Risk of developmental difficulties remains high among children born early

5 May, 2021 | 08:24h | UTC

Neurodevelopmental outcomes at age 5 among children born preterm: EPIPAGE-2 cohort study – The BMJ

News release: Risk of developmental difficulties remains high among children born early – The BMJ

Commentary on Twitter

Children born preterm remain at high risk of developmental difficulties that can affect their behaviour and ability to learn, finds new research https://t.co/0A1aIQWWqk #BMJResearch

— The BMJ (@bmj_latest) May 2, 2021

RCT: Community-initiated kangaroo mother care reduced the risk of moderate-to-severe maternal postpartum depressive symptoms among mothers of low-birth-weight infants in low-income areas in India

5 May, 2021 | 08:21h | UTC

Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress Among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

Skin to Skin care doesn’t only help babies; it also helps mothers!

Randomized trial of ~2k mothers from India found kangaroo care reduces postpartum depression #neoEBM #mentalhealth @JAMANetworkOpen https://t.co/6YqPQChKLe pic.twitter.com/DYAbU3Tsxu

— Abdul Razak, MD, FRCPCH (@DrAbdulRazak_MD) April 23, 2021

RCT: Discontinuing nasal continuous positive airway pressure either at 5 cm H2O vs. 3 cm H2O in infants ≤32 weeks of gestational age

3 May, 2021 | 05:15h | UTC

Discontinuing Nasal Continuous Positive Airway Pressure in Infants ≤32 Weeks of Gestational Age: A Randomized Control Trial – The Journal of Pediatrics (link to abstract – $ for full-text)

Commentary on Twitter

Randomized trial finds stopping CPAP at 5 cm H2O versus weaning until 3 cm H2O & then stopping is no different except babies will less likely to fail the initial attempt of discontinuation in weaning group (wean until 3 cm & then stop)@EBNEO @JPediatr https://t.co/G5yNK3fD1b

— Abdul Razak, MD, FRCPCH (@DrAbdulRazak_MD) October 27, 2020

Cohort study: Association of maternal SARS-CoV-2 infection in pregnancy with neonatal outcomes – “although babies born of test-positive mothers are more likely to be born early, extremely few were infected with COVID-19”

30 Apr, 2021 | 08:17h | UTC

Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes – JAMA

News release: Low risk of infection in babies born to mothers with COVID-19 – Karolinska Institutet

Editorial: Understanding Risk for Newborns Born to SARS-CoV-2–Positive Mothers – JAMA

Commentary on Twitter

Maternal #SARSCoV2 infection in pregnancy was significantly associated with small increases in the absolute risk of respiratory disorders and some other neonatal morbidities https://t.co/ANkXkaxnwp

— JAMA (@JAMA_current) April 29, 2021

Pre-post study: A hospital quality improvement intervention significantly reduced the rates of cesarean delivery for nulliparous, term, singleton, vertex births

29 Apr, 2021 | 08:21h | UTC

Hospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California – JAMA (free for a limited period)

Editorial: Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births – JAMA

Commentary on Twitter (thread – click for more)

"Rates of cesarean delivery for NTSV births in California decreased [from 26% to 22.8%] in the setting of a coordinated hospital-level collaborative and statewide initiatives designed to support vaginal birth.

"The rest of the US had no change."https://t.co/jwKkQZ4nix @cmqcc

— Ben Harder #BlackLivesMatter (@benharder) April 27, 2021

Covid-19: More data on the increased risks to pregnant women and their newborn infants

23 Apr, 2021 | 08:44h | UTC

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study – JAMA Pediatrics

Editorial: COVID-19 in Pregnant Women and Their Newborn Infants

Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN

Commentary on Twitter

18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz

— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

22 Apr, 2021 | 08:49h | UTC

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons – New England Journal of Medicine

Audio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine

Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News

Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions

22 Apr, 2021 | 08:19h | UTC

Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions – Agency for Healthcare Research and Quality

See also: Final Report AND Evidence Summary

NICE Guideline | Neonatal infection: antibiotics for prevention and treatment

21 Apr, 2021 | 06:46h | UTC

Neonatal infection: antibiotics for prevention and treatment – National Institute for Health and Care Excellence

NICE Guideline | Postnatal care

21 Apr, 2021 | 06:43h | UTC

Postnatal care – National Institute for Health and Care Excellence

Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

2 Apr, 2021 | 09:23h | UTC

Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis – The Lancet Global Health

Commentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health

Commentary on Twitter

NEW—Pregnancy outcomes worsened during the #COVID19 pandemic worldwide, with an increase in maternal deaths, stillbirth, ruptured ectopic pregnancies, and maternal depression.

New review of 40 studies from 17 countries in @LancetGH: https://t.co/GWBohu6b6k pic.twitter.com/4RzgtShYeH

— The Lancet (@TheLancet) April 1, 2021

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis

31 Mar, 2021 | 03:27h | UTC

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis – Canadian Medical Association Journal

Cohort study: Even small amounts of Caffeine consumption in pregnancy were linked to smaller neonatal birth size

28 Mar, 2021 | 22:14h | UTC

Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies–Singletons – JAMA Network Open

Commentaries: Even a Little Coffee in Pregnancy Could Impact Newborn’s Weight: Study – HealthDay AND Moderate daily caffeine intake during pregnancy may lead to smaller birth size – NIH News Releases

Commentary on Twitter

Cohort study finds even small amounts of caffeine consumption in pregnancy were associated with smaller birthweight and lean tissue measures, consistent for measured plasma caffeine/paraxanthine, and self-reported caffeine consumption. @NIH https://t.co/YzDVU6ejYO

— JAMA Network Open (@JAMANetworkOpen) March 25, 2021