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Pediatrics – Neonatal/Perinatal

Caring for two in the ICU: pharmacologic management of pregnancy-related complications

7 Aug, 2023 | 14:31h | UTC

Caring for two in the ICU: Pharmacologic management of pregnancy-related complications – Pharmacotherapy (free for a limited period)

 


M-A | Antenatal corticosteroid exposure linked to negative outcomes in term-born infants

4 Aug, 2023 | 11:59h | UTC

The proportions of term or late preterm births after exposure to early antenatal corticosteroids, and outcomes: systematic review and meta-analysis of 1.6 million infants – The BMJ

Related Study: Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study – The BMJ

Editorial: Antenatal corticosteroids and longer term outcomes – The BMJ

News Releases:

New studies shed more light on potential risks of antenatal steroids – BMJ Newsroom

Researchers find drugs that reduce infant death may lead to long-term health issues – McMaster University

 


Cohort Study | Antenatal corticosteroid exposure associated with increased incidence of pediatric serious infection

4 Aug, 2023 | 11:57h | UTC

Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study – The BMJ

Related Study: The proportions of term or late preterm births after exposure to early antenatal corticosteroids, and outcomes: systematic review and meta-analysis of 1.6 million infants – The BMJ

Editorial: Antenatal corticosteroids and longer term outcomes – The BMJ

 


M-A | Exploring perinatal interventions and their impact on severe intraventricular hemorrhage in preterm neonates

4 Aug, 2023 | 11:56h | UTC

Interventions to Reduce Severe Brain Injury Risk in Preterm Neonates: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


RCT – 2ry analysis | Use of NIPPV, NHFOV post-extubation outperforms NCPAP in neonates with severe respiratory failure or extremely preterm

4 Aug, 2023 | 11:48h | UTC

Effectiveness of Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation vs Noninvasive High-Frequency Oscillatory Ventilation as Support After Extubation of Neonates Born Extremely Preterm or With More Severe Respiratory Failure: A Secondary Analysis of a Randomized Clinical Trial – JAMA Network Open

Original Study: Noninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics

Related: Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation – Cochrane Library

 

Commentary on Twitter

 


Systematic Review | NIPPV potentially superior to NCPAP in reducing reintubation in extubated preterm neonates

4 Aug, 2023 | 11:46h | UTC

Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation – Cochrane Library

Related: M-A | Early NIPPV likely reduces the risk of respiratory failure and intubation in very preterm infants

 


Systematic Review | Necrotizing enterocolitis onset typically in third week for very preterm, low birthweight infants

3 Aug, 2023 | 13:33h | UTC

Age of onset of necrotising enterocolitis (NEC) and focal intestinal perforation (FIP) in very preterm and low birthweight infants: a systematic review – BMJ Open

 


Systematic Review | Probiotics’ potential in preventing necrotizing enterocolitis in very preterm, VLBW infants warrants further research

31 Jul, 2023 | 13:51h | UTC

Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants – Cochrane Library

 


Key factors associated with quality of postnatal care: a pooled analysis of 23 countries

25 Jul, 2023 | 13:50h | UTC

Key factors associated with quality of postnatal care: a pooled analysis of 23 countries – eClinicalMedicine

 


M-A | Early NIPPV likely reduces the risk of respiratory failure and intubation in very preterm infants

25 Jul, 2023 | 13:39h | UTC

Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants – Cochrane Library

 


RCT | Planned delivery from 34 weeks’ gestation effectively reduces pre-eclampsia related morbidity and mortality in LMICs

24 Jul, 2023 | 13:10h | UTC

Planned delivery or expectant management for late preterm pre-eclampsia in low-income and middle-income countries (CRADLE-4): a multicentre, open-label, randomised controlled trial – The Lancet

Related:

RCT | Planned delivery for pre-eclampsia between 34 and 37 weeks of gestation

M-A | Planned delivery or expectant management in preeclampsia.

Randomized Trial: Planned Early Delivery vs. Expectant Management for Late Preterm Pre-eclampsia

 


Phase 2 Trial | Maternal GBS6 vaccine shows promise in infant group B strep prevention

21 Jul, 2023 | 13:34h | UTC

Potential for Maternally Administered Vaccine for Infant Group B Streptococcus – New England Journal of Medicine

Commentary: Maternal strep B vaccine slashes risk of infection among infants – CIDRAP

 


Comparative Study | Genomic sequencing yields higher diagnostic results than targeted neonatal gene test in suspected genetic disorders

17 Jul, 2023 | 13:36h | UTC

Rapid Whole-Genomic Sequencing and a Targeted Neonatal Gene Panel in Infants With a Suspected Genetic Disorder – JAMA (link to abstract – $ for full-text)

Author Interview: Genomic Sequencing for Ill Newborns – JAMA

News Release: Genome sequencing highly effective at diagnosing genetic disorders in newborns and infants – Tufts University

 

Commentary on Twitter (thread – click for more)

 


Cohort Study | Intermittent hypoxemia is associated with unfavorable respiratory outcomes in extremely preterm infants

17 Jul, 2023 | 13:28h | UTC

Cardiorespiratory Monitoring Data to Predict Respiratory Outcomes in Extremely Preterm Infants – American Journal of Respiratory and Critical Care Medicine

 


Impact of newborn screening on severe combined immunodeficiency survival: results from a 36-year longitudinal study

14 Jul, 2023 | 12:45h | UTC

Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium – The Lancet (link to abstract – $ for full-text)

News Release: Newborn screening facilitates early identification of infants with severe combined immunodeficiency – NIH/National Institute of Allergy and Infectious Diseases/News Medical

 

Commentary on Twitter

 


AAP standards for levels of neonatal care: II, III, and IV

14 Jun, 2023 | 14:35h | UTC

Standards for Levels of Neonatal Care: II, III, and IV – Pediatrics

News Release: AAP sets national standards for levels of neonatal care – AAP News

Commentary: National Standards Developed for Neonatal Care – HealthDay

 


M-A | Kangaroo mother care reduces mortality in preterm and low birth weight infants

13 Jun, 2023 | 13:41h | UTC

Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis – BMJ Global Health

News Release: Effects of KMC in preterm and low birth weight infants – BMJ / News Medical

Related:

M-A | The efficacy of Kangaroo-Mother care to the clinical outcomes of LBW and premature infants

Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight – New England Journal of Medicine

Effect of community-initiated kangaroo mother care on survival of infants with low birthweight: a randomised controlled trial – The Lancet

Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress Among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial – JAMA Network Open

Kangaroo mother care to reduce morbidity and mortality in low birthweight infants – Cochrane Library

Preterm care during the COVID-19 pandemic: A comparative risk analysis of neonatal deaths averted by kangaroo mother care versus mortality due to SARS-CoV-2 infection – EclinicalMedicine

 


M-A | Elevated HbA1c in gestational diabetes mellitus tied to 1.7-fold rise in large for gestational age incidence

13 Jun, 2023 | 13:39h | UTC

Association between HbA1c Levels and Fetal Macrosomia and Large for Gestational Age Babies in Women with Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of 17,711 Women – Journal of Clinical Medicine

 


Guideline | Prevention and therapy of preterm birth

12 Jun, 2023 | 13:45h | UTC

Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG

Part 1: Recommendations on the Epidemiology, Etiology, Prediction, Primary and Secondary Prevention of Preterm Birth – Geburtshilfe und Frauenheilkunde

Part 2: Recommendations on the Tertiary Prevention of Preterm Birth and on the Management of Preterm Premature Rupture of Membranes – Geburtshilfe und Frauenheilkunde

 


M-A | Labor induction at 39 weeks: improved outcomes but increased shoulder dystocia for nulliparous women

31 May, 2023 | 14:10h | UTC

Comparison of Maternal Labor-Related Complications and Neonatal Outcomes Following Elective Induction of Labor at 39 Weeks of Gestation vs Expectant Management: A Systematic Review and Meta-analysis – JAMA Network Open

 


WHO Report | Global progress in tackling maternal and newborn deaths stalls since 2015

25 May, 2023 | 11:36h | UTC

News Release: Global progress in tackling maternal and newborn deaths stalls since 2015: UN – World Health Organization

Report: Improving maternal and newborn health and survival and reducing stillbirth – Progress report 2023 – World Health Organization

 


SR | Videolaryngoscopy vs. direct laryngoscopy for tracheal intubation in neonates

24 May, 2023 | 13:11h | UTC

Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates – Cochrane Library

 

Commentary on Twitter

 


WHO Report | 152 million babies born preterm in the last decade

23 May, 2023 | 13:15h | UTC

News Release: 152 million babies born preterm in the last decade – World Health Organization

Report: Born too soon: decade of action on preterm birth – World Health Organization

 


The Lancet Series | Small vulnerable newborns

23 May, 2023 | 13:13h | UTC

News Release: An estimated 1 million stillbirths and newborn baby deaths could be prevented each year with low-cost solutions – Lancet

Homepage: Small vulnerable newborns – The Lancet (free registration required for all articles)

Small vulnerable newborns—big potential for impact

Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting

Biological and pathological mechanisms leading to the birth of a small vulnerable newborn

Evidence-based antenatal interventions to reduce the incidence of small vulnerable newborns and their associated poor outcomes

The ethical, economic, and developmental imperative to prevent small vulnerable newborns and stillbirths: essential actions to improve the country and global response

 


SR | Nasal high flow therapy for primary respiratory support in preterm infants

12 May, 2023 | 13:31h | UTC

Nasal high flow therapy for primary respiratory support in preterm infants – Cochrane Library

Summary: Nasal high flow therapy for breathing support in preterm babies – Cochrane Library

 

Commentary on Twitter

 


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