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Endocrinology

Cohort Study | Modifiable risk factors may reduce the risk of type 2 diabetes in patients with a history of gestational diabetes.

23 Sep, 2022 | 13:08h | UTC

Modifiable risk factors and long term risk of type 2 diabetes among individuals with a history of gestational diabetes mellitus: prospective cohort study – The BMJ

News Release: Healthy lifestyle linked to 90% lower risk of diabetes in susceptible women – BMJ Newsroom

 

Commentary on Twitter

 


RCT | Insulin Glargine vs. Glimepiride vs. Sitagliptin vs. Liraglutide resulted in similar microvascular outcomes and death rates in patients with Type 2 diabetes not controlled with metformin.

22 Sep, 2022 | 13:20h | UTC

Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: Glycemia Reduction in Type 2 Diabetes — Glycemic Outcomes – New England Journal of Medicine

News Release: Two popular diabetes drugs outperformed others in large clinical trial – National Institutes of Health

 


Study shows that the leading causes of hospitalization of adults with diabetes are changing.

22 Sep, 2022 | 13:08h | UTC

Trends in leading causes of hospitalisation of adults with diabetes in England from 2003 to 2018: an epidemiological analysis of linked primary care records – The Lancet Diabetes & Endocrinology

Commentaries:

The changing character of diabetes complications – The Lancet Diabetes & Endocrinology (free registration required)

Reasons for hospital admissions in people with type 2 diabetes are changing – MedicalXpress

 


Review | Adrenal insufficiency in cirrhosis.

22 Sep, 2022 | 12:59h | UTC

Adrenal Insufficiency in Cirrhosis – Journal of the Endocrine Society

 


RCT | Effects of an exercise program on brain health outcomes for children with overweight or obesity.

21 Sep, 2022 | 13:17h | UTC

Effects of an Exercise Program on Brain Health Outcomes for Children With Overweight or Obesity: The ActiveBrains Randomized Clinical Trial – JAMA Network Open

News Release: Study finds schoolchildren who exercise perform better academically – University of Granada

Commentary: Exercise Improves Brain Health in Overweight, Obese Youth – HealthDay

 

Commentary on Twitter

 


Network M-A | Associations between statins and adverse events in secondary prevention of cardiovascular disease.

20 Sep, 2022 | 13:30h | UTC

Associations between statins and adverse events in secondary prevention of cardiovascular disease: Pairwise, network, and dose-response meta-analyses of 47 randomized controlled trials – Frontiers in Cardiovascular Medicine

 


RCT | Open-source automated insulin delivery in Type 1 Diabetes.

19 Sep, 2022 | 12:41h | UTC

Open-Source Automated Insulin Delivery in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Video summary: Open-Source Automated Insulin Delivery in Type 1 Diabetes – NEJM

Commentaries:

Open-Source AID Systems Can Improve Glycemic Control in Both Children and Adults with Type 1 Diabetes – Endocrinology Network

Automated Insulin Delivery Ups Time in Target Glucose Range in T1D – HealthDay

 


Cohort Study | Patients diagnosed with diabetes by oral glucose tolerance test without elevated HbA1c had similar cardiovascular and renal disease risks as those without diabetes.

15 Sep, 2022 | 13:12h | UTC

Risk of Macrovascular and Microvascular Disease in Diabetes Diagnosed Using Oral Glucose Tolerance Test With and Without Confirmation by Hemoglobin A1c: The Whitehall II Cohort Study – Circulation

Commentary: Patients diagnosed by OGTT without elevated HbA1c had similar CV, renal disease risks as those without diabetes – ACP Diabetes

 

Commentary on Twitter

 


Consensus recommendations for the use of Automated Insulin Delivery (AID) technologies in clinical practice.

15 Sep, 2022 | 13:06h | UTC

Consensus Recommendations for the Use of Automated Insulin Delivery (AID) Technologies in Clinical Practice – Endocrine Reviews

 


Cohort Study | A 7-year study of the durability of improvements in pain, physical function, and work productivity after Roux-en-Y gastric bypass and sleeve gastrectomy.

15 Sep, 2022 | 13:03h | UTC

A 7-Year Study of the Durability of Improvements in Pain, Physical Function, and Work Productivity After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy – JAMA Network Open

News Release: Beyond weight loss: Improvements in pain, mobility persist long after bariatric surgery – University of Pittsburgh

Author Interview: Long-term Changes in Pain, Physical Function, and Work Productivity After Bariatric Surgery – JAMA

 


USPSTF Statement | The current evidence is insufficient to recommend routine screening for prediabetes and type 2 diabetes in children and adolescents.

14 Sep, 2022 | 13:23h | UTC

Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: US Preventive Services Task Force Recommendation Statement – JAMA

Editorials:

Recommendations for Screening Children and Adolescents for Prediabetes and Type 2 Diabetes – JAMA

Broader Screening for Youth-Onset Type 2 Diabetes—We Just Are Not There Yet – JAMA Network Open

Evidence Report: Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents: Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Screening for Type 2 Diabetes in Children and Adolescents – JAMA

Author Interview: USPSTF Recommendation: Screening for Prediabetes and Diabetes in Children and Adolescents – JAMA

 


Expert Opinion | Clinical management of pregnancy in women with polycystic ovary syndrome.

14 Sep, 2022 | 13:02h | UTC

Clinical management of pregnancy in women with polycystic ovary syndrome: An expert opinion – Clinical Endocrinology

 


Cluster RCT | Tighter vs. less tight glycemic targets for women with gestational diabetes mellitus for reducing maternal and perinatal morbidity.

13 Sep, 2022 | 13:21h | UTC

Tighter or less tight glycaemic targets for women with gestational diabetes mellitus for reducing maternal and perinatal morbidity: A stepped-wedge, cluster-randomised trial – PLOS Medicine

 


Levoketoconazole in the treatment of patients with endogenous Cushing’s syndrome: a double-blind, placebo-controlled, randomized withdrawal study.

13 Sep, 2022 | 13:02h | UTC

Levoketoconazole in the treatment of patients with endogenous Cushing’s syndrome: a double-blind, placebo-controlled, randomized withdrawal study – Pituitary

Related study: Efficacy and safety of levoketoconazole in the treatment of endogenous Cushing’s syndrome (SONICS): a phase 3, multicentre, open-label, single-arm trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 


RCT | In youths with new-onset type 1 diabetes, intensive glucose control for 24 months with a closed-loop system did not help to preserve pancreatic function.

11 Sep, 2022 | 22:57h | UTC

Closed-Loop Therapy and Preservation of C-Peptide Secretion in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

MedH researcher on new study on preserved insulin production in type 1 diabetes – Karolinska Institutet

Preservation of C-Peptide Secretion Examined in Youth With T1D – HealthDay

 

Commentary on Twitter (video summary)

 


Cohort study showed a possible link between artificial sweeteners and heart disease.

11 Sep, 2022 | 22:55h | UTC

News Release: Possible link between artificial sweeteners and heart disease – BMJ Newsroom

Original Study: Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort – The BMJ

 


A randomized crossover trial with 12 patients showed that a bihormonal “artificial pancreas” with closed-loop glucose control increases patients’ time on euglycemia after total pancreatectomy.

11 Sep, 2022 | 22:45h | UTC

Bihormonal Artificial Pancreas With Closed-Loop Glucose Control vs Current Diabetes Care After Total Pancreatectomy: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Novel Bihormonal Artificial Pancreas Beneficial After Pancreatectomy – HealthDay

 


Network M-A | Comparative efficacy of lipid‐lowering therapies added to maximally tolerated statins for the reduction of LDL cholesterol.

11 Sep, 2022 | 22:38h | UTC

Network Meta‐Analysis of Randomized Trials Evaluating the Comparative Efficacy of Lipid‐Lowering Therapies Added to Maximally Tolerated Statins for the Reduction of Low‐Density Lipoprotein Cholesterol – Journal of the American Heart Association

 


Systematic Review | Surgery for the treatment of obesity in children and adolescents.

11 Sep, 2022 | 22:29h | UTC

Surgery for the treatment of obesity in children and adolescents – Cochrane Library

Summary: Surgery for the treatment of obesity in children and adolescents – Cochrane Library

 


Study shows bariatric surgery is more effective than lifestyle for type 2 diabetes remission.

8 Sep, 2022 | 14:27h | UTC

News Release: Bariatric surgery more effective than lifestyle for type 2 diabetes remission – Pennington Biomedical Research Center

Original Study: Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) – Diabetes Care

 


M-A | Hypocalcemia following thyroidectomy among patients who have previously undergone bariatric surgery.

8 Sep, 2022 | 14:25h | UTC

Hypocalcaemia following thyroidectomy among patients who have previously undergone bariatric surgery: systematic review and meta-analysis – British Journal of Surgery (link to abstract – $ for full-text)

 


RCT | Advanced hybrid closed loop therapy versus conventional treatment in adults with type 1 diabetes.

7 Sep, 2022 | 12:30h | UTC

Advanced hybrid closed loop therapy versus conventional treatment in adults with type 1 diabetes (ADAPT): a randomised controlled study – The Lancet Endocrinology (link to abstract – $ for full-text)

Commentary: ‘Artificial Pancreas’ Best in Poorly Controlled Type 1 Diabetes – Medscape (free registration required)

 

Commentary on Twitter

 


RCT | Weekly Somapacitan is noninferior to daily GH in children with GH deficiency.

6 Sep, 2022 | 14:25h | UTC

Weekly Somapacitan is Effective and Well Tolerated in Children with GH Deficiency: The Randomized Phase 3 REAL4 Trial – The Journal of Clinical Endocrinology & Metabolism

 


The Australian obesity management algorithm: a simple tool to guide the management of obesity in primary care.

5 Sep, 2022 | 14:31h | UTC

The Australian Obesity Management Algorithm: A simple tool to guide the management of obesity in primary care – Obesity Research & Clinical Practice

 


Nonalcoholic fatty liver disease: review of management for primary care providers.

5 Sep, 2022 | 14:18h | UTC

Nonalcoholic Fatty Liver Disease: Review of Management for Primary Care Providers – Mayo Clinic Proceedings

 


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