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Endocrinology

Bioethics | Should clinical guidelines incorporate cost pathways for persons with financial hardship?

28 Feb, 2021 | 20:54h | UTC

Should Clinical Guidelines Incorporate Cost Pathways for Persons With Financial Hardship? – AMA Journal of Ethics

 


COVID-19 hospitalizations attributable to cardiometabolic conditions

26 Feb, 2021 | 08:40h | UTC

Coronavirus Disease 2019 Hospitalizations Attributable to Cardiometabolic Conditions in the United States: A Comparative Risk Assessment Analysis – Journal of the American Heart Association

Commentary: Study estimates two-thirds of COVID-19 hospitalizations due to four conditions – Tufts University

 

Commentary on Twitter

 


Study: Unhealthy alcohol use common after bariatric surgery

26 Feb, 2021 | 08:14h | UTC

Association of Bariatric Surgical Procedures With Changes in Unhealthy Alcohol Use Among US Veterans – JAMA Network Open

Commentaries: Unhealthy Alcohol Use—A Common Iatrogenic Complication of Bariatric Surgery – JAMA Network Open AND Bariatric Surgery May Increase Risk of Unhealthy Alcohol Use – Psychiatric News Alert AND Bariatric Surgery Ups Risk of Alcohol Abuse – Physician’s Weekly

 

Commentary on Twitter

 


Series of n-of-1 trials show no difference in muscle symptoms in patients receiving placebo or statins

25 Feb, 2021 | 08:54h | UTC

Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials – The BMJ

Commentary: Do statins cause muscle symptom side effects? – The BMJ Opinion AND Study: Muscle Symptoms Didn’t Differ Between Statin and Placebo Periods – NEJM Journal Watch

Related study: #AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo (study and commentaries)

 


RCT: Effect of high-dose subcutaneous Semaglutide vs. placebo in adults with overweight or obesity

25 Feb, 2021 | 08:52h | UTC

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity: The STEP 3 Randomized Clinical Trial – JAMA

Commentary: Semaglutide paired with intensive behavioral therapy showed triple weight loss vs placebo – University of Pennsylvania School of Medicine

Related study: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults – New England Journal of Medicine (study and commentary)

 

Commentary on Twitter

 


Cohort study: High glycemic index diets are linked to increased risk of cardiovascular disease and death

25 Feb, 2021 | 08:49h | UTC

Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality – New England Journal of Medicine

Commentaries: Study finds diet high in poor quality carbohydrates increases heart disease and death – McMaster University AND High Glycemic Index Diets Linked to CVD and Mortality – TCTMD

 


SR: Metformin has modest efficacy for children with obesity

24 Feb, 2021 | 02:08h | UTC

Efficacy and Safety of Metformin for Obesity: A Systematic Review – Pediatrics (link to abstract – $ for full-text)

Commentary: Metformin Underwhelms in Pediatric Obesity – Physician’s Weekly

 


Meta-analysis: Effect of food variety on intake of a meal

21 Feb, 2021 | 21:33h | UTC

Effect of food variety on intake of a meal: a systematic review and meta-analysis – American Journal of Clinical Nutrition

 


RCT: Levothyroxine does not reduce the risk of developing depressive symptoms in older adults with subclinical hypothyroidism

18 Feb, 2021 | 02:46h | UTC

Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial – JAMA Network Open

Related Studies: Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine AND L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial – Annals of Internal Medicine

Guidelines (conflicting viewpoints): BMJ Guideline: Treatment of Subclinical Hypothyroidism AND Society for Endocrinology & British Thyroid Association issue statement against new treatment recommendations for subclinical hypothyroidism

 

Commentary on Twitter

 


SR: Concomitant use of levothyroxine and proton pump inhibitors causes a significant increase in TSH concentration

18 Feb, 2021 | 02:48h | UTC

Concomitant Use of Levothyroxine and Proton Pump Inhibitors in Patients with Primary Hypothyroidism: a Systematic Review – Journal of General Internal Medicine

 


Dieting may slow metabolism – but it doesn’t ruin it

18 Feb, 2021 | 02:44h | UTC

Dieting may slow metabolism – but it doesn’t ruin it – The Conversation

 


M-A: Intake of dietary fats and fatty acids and the incidence of type 2 diabetes

16 Feb, 2021 | 01:59h | UTC

Intake of dietary fats and fatty acids and the incidence of type 2 diabetes: A systematic review and dose-response meta-analysis of prospective observational studies – PLOS Medicine

 


RCT: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults

11 Feb, 2021 | 02:09h | UTC

Once-Weekly Semaglutide in Adults with Overweight or Obesity – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Semaglutide Plus Lifestyle Change Shown Effective for Obesity – NEJM Journal Watch

 

Commentary on Twitter

 


Randomized, cross-over trial: Compared to Mediterranean diet, a Low-fat vegan diet is better at improving body weight, lipid concentrations, and insulin sensitivity

11 Feb, 2021 | 01:56h | UTC

A Mediterranean Diet and Low-Fat Vegan Diet to Improve Body Weight and Cardiometabolic Risk Factors: A Randomized, Cross-over Trial – Journal of the American College of Nutrition

Commentary: Vegan diet associated with more weight loss, better cholesterol control than Mediterranean diet – Cardiovascular Business

Commentary: Vegan diet associated with more weight loss, better cholesterol control than Mediterranean diet – Cardiovascular Business

 

Commentary on Twitter

 


Red Yeast Rice for Hypercholesterolemia: JACC Focus Seminar

11 Feb, 2021 | 01:54h | UTC

Red Yeast Rice for Hypercholesterolemia: JACC Focus Seminar – Journal of the American College of Cardiology

 


Consensus statement: Cardiovascular health after menopause transition, pregnancy disorders, and other gynecologic conditions

10 Feb, 2021 | 01:25h | UTC

Cardiovascular health after menopause transition, pregnancy disorders, and other gynaecologic conditions: a consensus document from European cardiologists, gynaecologists, and endocrinologists – European Heart Journal

Commentary: ESC Consensus Document Provides Guidance on CV Risk in Women After Menopause, Pregnancy Disorders, Gynecologic Conditions – American College of Cardiology

 

Commentary on Twitter

 


SR: Long‐term effects of weight‐reducing diets in people with hypertension

10 Feb, 2021 | 01:23h | UTC

Long‐term effects of weight‐reducing diets in people with hypertension – Cochrane Library

Summary: Do weight-loss diets affect blood pressure, and reduce the effects of high blood pressure (hypertension)? – Cochrane Library

 


Cohort study: Characteristics and outcomes of pregnant women with type 1 or type 2 diabetes

10 Feb, 2021 | 01:16h | UTC

Characteristics and outcomes of pregnant women with type 1 or type 2 diabetes: a 5-year national population-based cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 

Commentaries on Twitter

 


Cohort study: Low risk of progression to diabetes among older adults with “prediabetes”

9 Feb, 2021 | 01:09h | UTC

Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine (free for a limited period)

Commentaries: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health AND Prediabetes—A Risk Factor Twice Removed – JAMA Internal Medicine (free for a limited period) AND How many pre-diabetics go on to develop diabetes? – MedicalResearch.com

Author Interview: Risk of Progression to Diabetes Among Older Adults With Prediabetes

Related: The war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science

 


M-A: Effects of whole grain intake, compared with refined grain, on appetite and energy intake

9 Feb, 2021 | 00:50h | UTC

Effects of Whole Grain Intake, Compared with Refined Grain, on Appetite and Energy Intake: A Systematic Review and Meta-Analysis – Advances in Nutrition

 

Commentary on Twitter

 


SR/MA: Up to a third of patients may discontinue thyroid hormone replacement and remain euthyroid

7 Feb, 2021 | 21:02h | UTC

Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis – Thyroid (link to abstract – $ for full-text)

Commentary: A Third Discontinuing Levothyroxine Have Normal Thyroid Levels – Medscape (free registration required)

 

Commentaries on Twitter

(thread – click for more)

 


Cohort study: Increased consumption of refined grains linked to higher risk of mortality and major cardiovascular disease events

5 Feb, 2021 | 01:30h | UTC

Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries in Prospective Urban and Rural Epidemiology study: prospective cohort study – The BMJ

Commentaries: Refined carbs like white bread, pasta, and pastries could increase risk of early death, a study found – Insider AND High intake of refined grains linked to higher risk of heart disease and death – The BMJ

 


Intermittent fasting may be effective weight loss strategy in patients with type 2 diabetes

4 Feb, 2021 | 01:00h | UTC

Intermittent fasting may be effective weight loss strategy in patients with type 2 diabetes – ACP Diabetes

Original Study: Metabolic Impact of Intermittent Fasting in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis of Interventional Studies – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)

 


AAP urges continuing obesity management

2 Feb, 2021 | 01:03h | UTC

AAP urges continuing obesity management – Contemporary Pediatrics

Original Guideline: Obesity Management and Treatment During COVID-19 – American Academy of Pediatrics

 


Management of diabetes and hyperglycemia in the hospital

29 Jan, 2021 | 01:34h | UTC

Management of diabetes and hyperglycaemia in the hospital – The Lancet Diabetes & Endocrinology (free for a limited period)

 

Commentary on Twitter

 


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