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Endocrinology

Clinical review of subcutaneous Semaglutide for obesity.

24 Jan, 2022 | 07:54h | UTC

Clinical review of subcutaneous semaglutide for obesity – Journal of Clinical Pharmacy and Therapeutics

 

RCT: In very young children with Type 1 Diabetes, a hybrid closed-loop therapy (“artificial pancreas”) resulted in better glycemic control without increased risk of hypoglycemia vs. sensor-augmented pump therapy.

20 Jan, 2022 | 09:07h | UTC

Randomized Trial of Closed-Loop Control in Very Young Children with Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Artificial pancreas proves ‘life-changing’ for very young children with type 1 diabetes and their families – University of Cambridge

 

Review: Diagnosis and treatment of polycystic ovary syndrome.

20 Jan, 2022 | 08:54h | UTC

Diagnosis and Treatment of Polycystic Ovary Syndrome – JAMA (free for a limited period)

 

Consensus Statement: Exercise/physical activity in individuals with Type 2 Diabetes.

20 Jan, 2022 | 08:51h | UTC

Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine – Medicine & Science in Sports & Exercise

 

Commentary from the author on Twitter

 

M-A: Association of Sodium-Glucose Cotransporter 2 Inhibitors with cardiovascular outcomes in patients with Type 2 Diabetes and other risk factors for cardiovascular disease.

20 Jan, 2022 | 08:42h | UTC

Association of Sodium-Glucose Cotransporter 2 Inhibitors With Cardiovascular Outcomes in Patients With Type 2 Diabetes and Other Risk Factors for Cardiovascular Disease: A Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 

Cohort study: In patients who underwent bariatric surgery, those submitted to gastric bypass were slightly more likely to remain free of obesity-related medications during follow-up compared with those who underwent sleeve gastrectomy.

18 Jan, 2022 | 09:31h | UTC

Medication Use for Obesity-Related Comorbidities After Sleeve Gastrectomy or Gastric Bypass – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Gastric Bypass Tied to Modest Shift in Need for Comorbidity Meds – MedPage Today (free registration required)

 

Commentary on Twitter

 

Association of hormonal contraceptive use with adverse health outcomes: an umbrella review of meta-analyses of randomized clinical trials and cohort studies.

18 Jan, 2022 | 09:29h | UTC

Association of Hormonal Contraceptive Use With Adverse Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials and Cohort Studies – JAMA Network Open

 

Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide.

18 Jan, 2022 | 09:23h | UTC

Treating Acne in Transgender Persons Receiving Testosterone: A Practical Guide – American Journal of Clinical Dermatology

 

ERAS Guidelines for perioperative care in bariatric surgery.

16 Jan, 2022 | 23:21h | UTC

Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations: A 2021 Update – World Journal of Surgery

Related: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

 

Commentary on Twitter

 

RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

16 Jan, 2022 | 23:13h | UTC

The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Related:

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Research: Circulating vitamin D concentration and risk of seven cancers

Research: Vitamin D and risk of total and site specific cancers

 

RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

16 Jan, 2022 | 23:11h | UTC

Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial-a randomized controlled trial – American Journal of Clinical Nutrition

News Release: Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer – University of Eastern Finland

Related:

Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Research: Circulating vitamin D concentration and risk of seven cancers

Research: Vitamin D and risk of total and site specific cancers

 

Perspective: Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age.

16 Jan, 2022 | 22:53h | UTC

Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age – Family Medicine and Community Health

Commentaries:

Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’ – Florida Atlantic University

Preventive Aspirin Should Be Based on Benefit, Not Age – HealthDay

Related: USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.

 

Assessment and treatment of thyroid disorders in pregnancy and the postpartum period.

16 Jan, 2022 | 22:42h | UTC

Assessment and treatment of thyroid disorders in pregnancy and the postpartum period – Nature Reviews Endocrinology (if the link is paywalled, try this one)

 

Commentary on Twitter

 

RCT: In patients with acromegaly who previously tolerated and responded to both regimens, oral octreotide was non-inferior for maintaining biochemical response and symptomatic control compared to injectable somatostatin receptor ligands.

14 Jan, 2022 | 07:55h | UTC

Maintenance of response to oral octreotide compared with injectable somatostatin receptor ligands in patients with acromegaly: a phase 3, multicentre, randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 

The year in cardiovascular medicine 2021: diabetes and metabolic disorders.

13 Jan, 2022 | 08:33h | UTC

The year in cardiovascular medicine 2021: diabetes and metabolic disorders – European Heart Journal

 

The year in cardiovascular medicine 2021: dyslipidemia.

13 Jan, 2022 | 08:30h | UTC

The year in cardiovascular medicine 2021: dyslipidemia – European Heart Journal

 

M-A: Intermittent Fasting and Obesity-Related Health Outcomes.

13 Jan, 2022 | 08:22h | UTC

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

 

RCT: High-dose weekly Semaglutide (2.4 mg) resulted in increased weight loss compared to daily Liraglutide (3.0 mg).

12 Jan, 2022 | 08:55h | UTC

Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

 

Cohort Study: Higher consumption of olive oil linked to lower risk of cardiovascular, cancer, and all-cause mortality.

12 Jan, 2022 | 08:41h | UTC

Consumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

Higher olive oil intake associated with lower risk of CVD mortality – American College of Cardiology

Higher Olive Oil Intake May Be Associated With Lower Risk of CVD Mortality – American College of Cardiology

 

AHA Scientific Statement: Comprehensive management of cardiovascular risk factors for adults with Type 2 Diabetes.

11 Jan, 2022 | 02:40h | UTC

Comprehensive Management of Cardiovascular Risk Factors for Adults With Type 2 Diabetes: A Scientific Statement From the American Heart Association – Circulation

News Release: Fewer than 1 in 5 adults with Type 2 diabetes in the U.S. are meeting optimal heart health targets – American Heart Association

 

Guideline: ADA 2022 Standards of Medical Care in Diabetes.

24 Dec, 2021 | 13:38h | UTC

Guideline Homepage: ADA 2022 Standards of Medical Care in Diabetes – American Diabetes Association

Introduction: Standards of Medical Care in Diabetes—2022

Summary of Revisions: Standards of Medical Care in Diabetes—2022

Standards of Medical Care in Diabetes—2022 Guideline Abridged for Primary Care Providers

Video Summary: Standards of Care in Diabetes – 2022

  1. Improving Care and Promoting Health in Populations
  2. Classification and Diagnosis of Diabetes 
  3. Prevention or Delay of Type 2 Diabetes and Associated Comorbidities
  4. Comprehensive Medical Evaluation and Assessment of Comorbidities
  5. Facilitating Behavior Change and Well-being to Improve Health Outcomes
  6. Glycemic Targets
  7. Diabetes Technology
  8. Obesity and Weight Management for the Prevention and Treatment of Type 2 Diabetes
  9. Pharmacologic Approaches to Glycemic Treatment
  10. Cardiovascular Disease and Risk Management
  11. Chronic Kidney Disease and Risk Management
  12. Retinopathy, Neuropathy, and Foot Care
  13. Older Adults
  14. Children and Adolescents
  15. Management of Diabetes in Pregnancy
  16. Diabetes Care in the Hospital
  17. Diabetes Advocacy

 

Commentaries on Twitter

 

AAN Guideline: Oral and topical treatment of painful diabetic polyneuropathy.

8 Jan, 2022 | 23:18h | UTC

Oral and Topical Treatment of Painful Diabetic Polyneuropathy: Practice Guideline Update Summary: Report of the AAN Guideline Subcommittee – Neurology

News Release: AAN Issues Guideline for Treatment of Painful Diabetic Neuropathy – American Academy of Neurology

 

NICE Guideline | Type 2 diabetes in adults: management.

17 Dec, 2021 | 08:45h | UTC

Type 2 diabetes in adults: management – National Institute for Health and Care Excellence

Related: Guideline: ADA 2021 Standards of Medical Care in Diabetes

 

Review: Impact of obesity in critical illness.

16 Dec, 2021 | 08:45h | UTC

Impact of Obesity in Critical Illness – CHEST

 

M-A: Pharmacotherapy for adults with overweight and obesity – “phentermine–topiramate and GLP-1 receptor agonists proved the best drugs in reducing weight”.

15 Dec, 2021 | 08:30h | UTC

Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 

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