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Endocrinology

RCT: The combination of liraglutide + exercise improves weight loss maintenance more than either treatment alone.

6 May, 2021 | 08:52h | UTC

Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined – New England Journal of Medicine

Commentary: Liraglutide beneficial for post-diet weight loss maintenance – Medwire News

 

Consensus Statement: Post-exercise recovery for the endurance athlete with type 1 diabetes.

6 May, 2021 | 08:42h | UTC

Post-exercise recovery for the endurance athlete with type 1 diabetes: a consensus statement – The Lancet Diabetes & Endocrinology (free registration required)

 

Commentary on Twitter

 

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

5 May, 2021 | 08:30h | UTC

Draft Recommendation Statement: Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer – U.S. Preventive Services Task Force

Draft Evidence Review: Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer

 

Study with 6.9 million people in England shows severe Covid-19 in young people can mostly be explained by obesity – At a BMI of more than 23 kg/m2, there was a linear increase in risk of severe COVID-19

30 Apr, 2021 | 08:22h | UTC

Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study – The Lancet Diabetes & Endocrinology

Commentaries: Severe COVID in young people can mostly be explained by obesity – new study – The Conversation AND Obesity studies highlight severe COVID outcomes, even in young adults – CIDRAP AND Expert reaction to study looking at a potential link between body weight and risk of severe COVID-19, especially for younger adults – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 

AHA Scientific Statement: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormonal therapies

29 Apr, 2021 | 08:33h | UTC

Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications: A Scientific Statement From the American Heart Association – Circulation: Genomic and Precision Medicine

News release: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormones – American Heart Association

Top Things to Know: Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System – American Heart Association

Commentaries: Hormonal Therapy for Breast and Prostate Cancer: Lessons and Opportunities – American Heart Association AND Hormonal Based Therapies in the Treatment of Breast and Prostate Cancer – balancing the risks! – American Heart Association AND Hormone Cancer Therapies Increase CV Risk: AHA Scientific Statement – TCTMD AND Closely Monitor Heart Health in Cancer Patients Who Get Hormonal Therapies: AHA – HealthDay

 

Review: Non-alcoholic fatty liver disease

29 Apr, 2021 | 08:30h | UTC

Non-alcoholic fatty liver disease – The Lancet (free for a limited period)

 

RCT: Metformin vs. insulin in gestational diabetes – metformin was associated better glycemic control, lower risk of hypoglycemia, and less maternal weight gain

25 Apr, 2021 | 21:03h | UTC

MeDiGes Study. Metformin versus insulin in gestational diabetes: Glycemic control, and obstetrical and perinatal outcomes. Randomized prospective trial. – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Related: Randomized trial tests metformin in women with type 2 diabetes in pregnancy AND Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis – PLOS Medicine AND Case-Control Study: Metformin Exposure in First Trimester of Pregnancy is Not Associated with Congenital Anomalies

 

AHA Scientific Statement: Obesity and Cardiovascular Disease

23 Apr, 2021 | 08:22h | UTC

Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association – Circulation

News Release: More belly weight increases danger of heart disease even if BMI does not indicate obesity – American Heart Association

Commentary: It’s time to measure your waistline, according to new recommendations. Belly fat raises your risk for disease – CNN

 

Survey: Despite guideline recommendations, many patients with low-risk thyroid cancer continue to be treated with suppressive doses of thyroid hormone

23 Apr, 2021 | 08:13h | UTC

TSH Suppression for Papillary Thyroid Cancer: A Physician Survey Study – Thyroid (link to abstract – $ for full-text)

 

Commentary on Twitter

 

AGA recommends intragastric balloons as an additional weight loss option for obese patients

23 Apr, 2021 | 08:10h | UTC

AGA recommends intragastric balloons as an additional weight loss strategy for obese patients – American Gastroenterological Association

Original article: AGA Clinical Practice Guidelines on Intragastric Balloons in the Management of Obesity – Gastroenterology

 

Study: Postprandial glycemic dips predict appetite and energy intake in healthy individuals

21 Apr, 2021 | 06:36h | UTC

Postprandial glycaemic dips predict appetite and energy intake in healthy individuals – Nature Metabolism

Commentaries: New research reveals why some of us are hungry all the time – King’s College London AND The easy test that predicts the size of your next few meals – Nature AND Feeling Hungry All The Time? Scientists Have a New Explanation For What’s Going On – Science Alert

 

Commentary on Twitter

 

M-A: Portal venous system thrombosis after bariatric surgery

21 Apr, 2021 | 06:16h | UTC

Portal venous system thrombosis after bariatric surgery: A systematic review and meta-analysis – Surgery (link to abstract – $ for full-text)

 

Podcast: Management of Obesity Hypoventilation Syndrome

20 Apr, 2021 | 05:23h | UTC

#269 Obesity Hypoventilation Syndrome (OHS) and the Didgeridoo with Dr Aneesa Das – The Curbsiders

 

Study: Teprotumumab for patients with active thyroid eye disease

20 Apr, 2021 | 05:25h | UTC

Teprotumumab for patients with active thyroid eye disease: a pooled data analysis, subgroup analyses, and off-treatment follow-up results from two randomised, double-masked, placebo-controlled, multicentre trials – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 

2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult

18 Apr, 2021 | 21:24h | UTC

2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult – Canadian Journal of Cardiology

 

Commentary on Twitter

 

Review: Endocrine complications of immunotherapies

15 Apr, 2021 | 06:13h | UTC

Endocrine complications of immunotherapies: a review – Clinical Medicine Journal

 

WHO Calls For Expanding Access To Insulin At Launch of Global Diabetes Compact

15 Apr, 2021 | 06:25h | UTC

WHO Calls For Expanding Access To Insulin At Launch of Global Diabetes Compact – Health Policy Watch

News release: New WHO Global Compact to speed up action to tackle diabetes – World Health Organization

Guidance: WHO global diabetes compact – World Health Organization

 

USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening

14 Apr, 2021 | 01:47h | UTC

Vitamin D Deficiency in Adults: Screening – U.S. Preventive Services Task Force

Evidence Report: Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Editorial: The USPSTF 2021 Recommendations on Screening for Asymptomatic Vitamin D Deficiency in Adults: The Challenge for Clinicians Continues – JAMA AND Why USPSTF Still Finds Insufficient Evidence to Support Screening for Vitamin D Deficiency – JAMA Network Open

JAMA Patient Page: Screening for Vitamin D Deficiency in Adults

 

RCT: Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy

9 Apr, 2021 | 03:18h | UTC

Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial – JAMA Neurology

Author Interview: Effect of High-Frequency (10 kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy

 

Commentary on Twitter

 

Commentary | Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes?

9 Apr, 2021 | 03:28h | UTC

Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology

 

Chronic Coronary Syndromes in Women: Challenges in Diagnosis and Management

6 Apr, 2021 | 01:08h | UTC

Chronic Coronary Syndromes in Women: Challenges in Diagnosis and Management – Mayo Clinic Proceedings

 

RCT: Effect of intravitreous anti–vascular endothelial growth factor vs. sham treatment for prevention of vision-threatening complications of diabetic retinopathy

6 Apr, 2021 | 01:02h | UTC

Effect of Intravitreous Anti–Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy: The Protocol W Randomized Clinical Trial – JAMA Ophthalmology

Commentaries: Preventive treatment reduces diabetic retinopathy complications – NIH News Releases AND Prevention of Severe Nonproliferative Diabetic Retinopathy Progression With More at Stake Than Visual Acuity – JAMA Ophthalmology AND Practicality of Prophylactic Aflibercept to Reduce Diabetic Retinopathy Progression – JAMA Ophthalmology

Author interview: Randomized Trial of Anti-VEGF to Prevent Proliferative Diabetic Retinopathy (PDR) and Diabetic Macular Edema (DME) – JAMA

 

Commentary on Twitter

 

Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement

28 Mar, 2021 | 22:06h | UTC

Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement – Sports Medicine

 

RCT: Effect of continued weekly subcutaneous Semaglutide vs. placebo on weight loss maintenance in adults with overweight or obesity

24 Mar, 2021 | 08:05h | UTC

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial – JAMA (free for a limited period)

Commentaries: Continuing Semaglutide Leads to Further Weight Loss – NEJM Journal Watch AND STEP 4: Long-term treatment needed for full semaglutide benefit – MedwireNews

Podcast: Semaglutide for Weight Loss – JAMA

 

Commentary on Twitter

 

Ultra-Processed Foods and Incident Cardiovascular Disease in the Framingham Offspring Study

24 Mar, 2021 | 08:02h | UTC

Ultra-Processed Foods and Incident Cardiovascular Disease in the Framingham Offspring Study – Journal of the American College of Cardiology

Commentaries: Eating More Ultraprocessed ‘Junk’ Food Linked to Higher CVD Risk – TCTMD AND Ultra-Processed Foods and Incident Cardiovascular Disease – American College of Cardiology

 

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