GI Surgery – Esophagus
Sleeping on the LEFT side seems to be associated with reduced nocturnal acid exposure compared with supine and right lateral decubitus positions.
21 Jan, 2022 | 09:45h | UTCAssociations Between Sleep Position and Nocturnal Gastroesophageal Reflux: A Study Using Concurrent Monitoring of Sleep Position and Esophageal pH and Impedance – American Journal of Gastroenterology (link to abstract – $ for full-text)
M-A: Role of adjuvant therapy in esophageal cancer patients after neoadjuvant therapy and esophagectomy.
19 Jan, 2022 | 08:19h | UTCRole of Adjuvant Therapy in Esophageal Cancer Patients After Neoadjuvant Therapy and Esophagectomy: A Systematic Review and Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)
Commentary on Twitter
New in Annals! Meta-analysis examines the effect of adjuvant therapy on overall survival after esophagectomy
Free download – https://t.co/r2SY34ZiVE
Lee, Samarasinghe, @michaelhylee, @luxmy_thiru, @ShargallYaron, Finley, @wc_hanna, Levine, Juergens, Agzarian pic.twitter.com/UV4v6leCcr
— Annals of Surgery (@AnnalsofSurgery) November 2, 2021
Outcomes associated with caustic ingestion among 1198 adults in a national prospective database in France.
9 Dec, 2021 | 10:19h | UTCOutcomes Associated With Caustic Ingestion Among Adults in a National Prospective Database in France – JAMA Surgery (free for a limited period)
Invited commentary: Caustic Ingestion—The Haves and the Have Nots (free for a limited period)
Commentary on Twitter
Study provides nation-wide data regarding in-hospital patients' outcomes after caustic ingestion. Severity of ingestion and hospital volume are associated with mortality. If feasible, low volume hospitals should transfer patients to larger centers https://t.co/VbX1jhGbjJ
— JAMA Surgery (@JAMASurgery) December 8, 2021
M-A: Major adverse events related to endoscopic or laparoscopic procedures in achalasia.
7 Dec, 2021 | 08:33h | UTC
Guideline | Endoscopic tissue sampling – Part 1: Upper gastrointestinal and hepatopancreatobiliary tracts.
26 Nov, 2021 | 09:41h | UTC
ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.
23 Nov, 2021 | 08:40h | UTC
Commentary on Twitter (thread – click for more)
⭐️NEW @AmCollegeGastro guidelines on #GERD!⭐️
🔥 🤭 🌶 💊 ✂️
"A lot has changed, much remains the same." 🧵 ⬇️#MedTwitter #GITwitter #GI #motility #MedEd https://t.co/HS26GDk8Jd
— John Damianos, M.D. (@john_damianosMD) November 22, 2021
Clinical Guideline Highlights for the Hospitalist: Management of Upper Gastrointestinal and Ulcer Bleeding.
21 Nov, 2021 | 22:44h | UTCClinical Guideline Highlights for the Hospitalist: Management of Upper Gastrointestinal and Ulcer Bleeding – Journal of Hospital Medicine (free for a limited period)
Review and algorithm: Dysphagia aortica.
16 Nov, 2021 | 08:19h | UTCDysphagia aortica – European Surgery
M-A: Comparison of outcomes between neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy in patients with locally advanced esophageal cancer.
7 Nov, 2021 | 20:07h | UTC
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract.
27 Oct, 2021 | 01:35h | UTC
RCT: Effect of Camrelizumab vs. placebo added to chemotherapy on survival and progression-free survival in patients with advanced or metastatic esophageal squamous cell carcinoma.
15 Sep, 2021 | 08:51h | UTCEffect of Camrelizumab vs Placebo Added to Chemotherapy on Survival and Progression-Free Survival in Patients With Advanced or Metastatic Esophageal Squamous Cell Carcinoma: The ESCORT-1st Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma—Renewed Enthusiasm and a Lingering Challenge – JAMA Oncology (free for a limited period)
Commentary on Twitter
Among patients with advanced or metastatic esophageal squamous cell carcinoma, the addition of camrelizumab to chemotherapy, compared with placebo and chemotherapy, significantly improved overall survival and progression-free survival https://t.co/DAlhmtgvv1
— JAMA (@JAMA_current) September 14, 2021
SAGES guidelines for the surgical treatment of gastroesophageal reflux.
21 Jul, 2021 | 10:34h | UTCSAGES guidelines for the surgical treatment of gastroesophageal reflux (GERD) – Surgical Endoscopy
Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.
14 Jul, 2021 | 11:07h | UTCNews release: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet
Commentaries: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian AND Expert reaction to study of alcohol and cancer – Science Media Centre
RCT: Long-term efficacy of neoadjuvant chemoradiotherapy plus surgery for the treatment of locally advanced esophageal squamous cell carcinoma.
13 Jul, 2021 | 09:20h | UTC
Commentary on Twitter
Long-term outcomes from the NEOCRTEC5010 demonstrated the survival benefit of neoadjuvant chemoradiotherapy followed by surgery compared with surgery alone for patients with locally advanced esophageal squamous cell carcinoma https://t.co/UBBEEAynsy
— JAMA Surgery (@JAMASurgery) June 29, 2021
Ranitidine absolved? FDA study finds Ranitidine does not convert to carcinogen NDMA, regardless of diet.
12 Jul, 2021 | 01:36h | UTCEditorial: Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation
Commentary: Ranitidine: FDA finds no evidence of elevated NDMA, regardless of diet
Commentaries on Twitter
Despite ranitidine (zantac) being pulled from market last year, a new study from the FDA did not find evidence that it increases concentrations of the carcinogenic metabolite people were worried about (i.e., it's probably safe). From @JAMA_current https://t.co/AdRic2GdXS
— Zack Williams (@QuantPsychiatry) June 28, 2021
In this crossover, randomized clinical trial, oral ranitidine did not significantly increase 24-hour urinary excretion of NDMA when administered with a noncured-meats diet or a cured-meats diet. https://t.co/EszRvfJOFJ
— JAMA (@JAMA_current) June 28, 2021
RCT: Reduced-intensity chemotherapy among older and frail patients with advanced gastroesophageal cancer provides an improved patient experience with no significant detriment in cancer control.
20 May, 2021 | 08:18h | UTC
Commentary on Twitter
The GO2 trial tested reduced intensity of chemo for pts w adv gastroesophageal cancer & found reducing intensity led to comparable survival but w improved patient experience, & decision-making can be enhanced using geriatric assessment https://t.co/DtZOXcozo7 #GeriOnc
— JAMA Oncology (@JAMAOnc) May 13, 2021
Randomized trial long-term results confirm the benefits of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer
20 May, 2021 | 08:16h | UTC
Commentaries on Twitter
Out at @ASCO_pubs
🔟yr Outcome of Neoadj #Chemoradiotherapy➕Surgery for #EsophagealCancer☑️Show OS benefit in locally advanced resectable esophageal or junctional #Cancer who receive preop chemorad🧪☢️ According to CROSS, persists at least🔟years‼️https://t.co/yJSibSveAh pic.twitter.com/UssnzuFiEe
— Gil Morgan (@weoncologists) May 14, 2021
Survival benefit of preoperative chemoradiotherapy for patients with esophageal cancer persists – 10-year outcome of the CROSS trial https://t.co/s02sMVpYhI #esocsm #JCO @ErasmusMC @bmeyck pic.twitter.com/2JwV0iOvoB
— ASCO Publications (@ASCO_pubs) May 5, 2021
RCT: Among patients with esophageal cancer, intrathoracic anastomosis after totally or hybrid minimally invasive esophagectomy resulted in lower anastomotic leakage rates and better outcomes when compared with cervical anastomosis.
18 May, 2021 | 07:21h | UTCIntrathoracic vs Cervical Anastomosis After Totally or Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited commentary: Does the Location Matter for the Anastomosis for Minimally Invasive Esophagectomy? (free for a limited period)
Commentary on Twitter
Intrathoracic anastomosis after MIE is associated with a lower anastomotic leakage rate and better outcome for patients with mid to distal esophageal or gastro-esophageal junction cancer: results of the ICAN trial https://t.co/CXv2CeCnuX pic.twitter.com/QCYg4UJeyF
— JAMA Surgery (@JAMASurgery) May 12, 2021
ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding – RBC transfusion at a threshold of 7 g/dL; Erythromycin infusion is suggested before endoscopy; and endoscopy is suggested within 24 hours after presentation.
3 May, 2021 | 05:27h | UTC
M-A: Treatment for bleeding esophageal varices in people with decompensated liver cirrhosis
12 Apr, 2021 | 00:39h | UTCRelated Cochrane Reviews: M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis AND Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta‐analysis – Cochrane Library
Meta-Analysis: Primary prevention of variceal bleeding in people with esophageal varices due to liver cirrhosis
8 Apr, 2021 | 08:45h | UTCRelated Cochrane Review: M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis
M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis
5 Apr, 2021 | 01:17h | UTC
RCT: No benefit from palliative radiotherapy after esophageal cancer stenting
18 Mar, 2021 | 08:52h | UTC
Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers
24 Feb, 2021 | 02:00h | UTC
Randomized trial: Pneumatic dilation does not work for persistent dysphagia after antireflux surgery
19 Jan, 2021 | 01:13h | UTCPneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomised sham-controlled clinical trial – Gut (link to abstract – $ for full-text)