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General Surgery & Trauma

Diverticulitis: Observational study in outpatients suggests amoxicillin-clavulanate is a safe and effective option compared with metronidazole-fluoroquinolone

24 Feb, 2021 | 02:16h | UTC

Comparative Effectiveness and Harms of Antibiotics for Outpatient Diverticulitis: Two Nationwide Cohort Studies – Annals of Internal Medicine

Commentaries: Amoxicillin-clavulanate safe and effective compared with metronidazole-with-fluoroquinolone for diverticulitis – American College of Physicians AND Study supports fluoroquinolone-sparing treatment for diverticulitis – CIDRAP


Deep learning algorithm detects universal trauma on pelvic radiographs

24 Feb, 2021 | 02:03h | UTC

A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs – Nature Communications

Commentary: AI algorithm accurately detects trauma on pelvic radiographs – AuntMinnie


Commentary on Twitter


Cohort study: Tomographic radiation in patients who underwent appendectomy linked to increased risk of hematologic malignant neoplasms

22 Jan, 2021 | 08:25h | UTC

Risk of Hematologic Malignant Neoplasms From Abdominopelvic Computed Tomographic Radiation in Patients Who Underwent Appendectomy – JAMA Surgery (free for a limited period)

Commentary: Optimizing the Gold Standard—Low-Dose Computed Tomography Modalities as a Part of Clinical Practice in Acute Appendicitis Imaging – JAMA Surgery (free for a limited period)

Author Interview: Risk of Hematologic Malignant Neoplasms From Abdominopelvic CT Radiation


Meta-analysis: Comparison of the loop technique with incision and drainage for skin and soft tissue abscesses

20 Jan, 2021 | 01:22h | UTC

Comparison of the Loop Technique With Incision and Drainage for Skin and Soft Tissue Abscesses: A Systematic Review and Meta‐analysis – Academic Emergency Medicine


Commentary on Twitter


Postdischarge virtual visits for low-risk surgeries: A randomized noninferiority clinical trial

17 Jan, 2021 | 21:57h | UTC

Postdischarge Virtual Visits for Low-risk Surgeries: A Randomized Noninferiority Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Surgical Centers Warm Up to Video Chats, Texts for Patient Follow-Up – MedPage Today (free registration required)


Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

14 Jan, 2021 | 01:57h | UTC

Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial – JAMA

Editorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis

Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly


Commentary on Twitter


Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations

14 Jan, 2021 | 01:36h | UTC

Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations – Surgery (link to abstract – $ for full-text)


Observational study: Surgical decompression within 24 h of acute spinal cord injury is associated with improved sensorimotor recovery

13 Jan, 2021 | 01:49h | UTC

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data – The Lancet Neurology (link to abstract – $ for full-text)


Commentary on Twitter


Multiple trauma management in mountain environments – a scoping review

12 Jan, 2021 | 01:25h | UTC

Multiple trauma management in mountain environments – a scoping review – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine


Randomized trial: Ultra-early tranexamic acid does not improve outcomes after subarachnoid hemorrhage

10 Jan, 2021 | 21:02h | UTC

Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)



Randomized trial: Laparoscopic lavage vs. primary resection for perforated purulent diverticulitis; similar long-term results, but recurrence was more common after laparoscopic lavage

10 Jan, 2021 | 20:25h | UTC

Laparoscopic Lavage vs Primary Resection for Acute Perforated Diverticulitis: Long-term Outcomes From the Scandinavian Diverticulitis (SCANDIV) Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Laparoscopic Lavage a Safe Option in Perforated Diverticulitis — No difference versus resection in long-term severe complications, but recurrence more common – MedPage Today (free registration required)


Randomized trial: In surgical patients at moderate or high risk of venous thromboembolism, pharmaco-thromboprophylaxis alone is as good as the combination of pharmaco-thromboprophylaxis and graduated compression stockings

16 Dec, 2020 | 10:00h | UTC

Compression stockings in addition to low-molecular-weight heparin to prevent venous thromboembolism in surgical inpatients requiring pharmacoprophylaxis: the GAPS non-inferiority RC – Health Technology Assessment


Review: Perioperative venous thromboembolism prophylaxis

3 Dec, 2020 | 08:28h | UTC

Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings


Podcast on Wilderness Medicine: Pearls on altitude sickness, frostbite, animal bites, thermoregulation, and wound care

17 Nov, 2020 | 09:32h | UTC

#242 Wilderness Medicine: Prepare for Disaster – The Curbsiders Internal Medicine Podcast


Tranexamic acid after traumatic brain injury: Exploratory analysis combining data from CRASH-2 and CRASH-3 trials suggests reduced mortality

13 Nov, 2020 | 09:21h | UTC

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial – Critical Care

Commentary: New analysis combining data from the world’s largest trauma trials provides compelling evidence that rapid tranexamic acid treatment saves lives – London School of Hygiene & Tropical Medicine


Commentary on Twitter


Safe surgery: A cluster randomized trial showed that the implementation of control charts with feedback on indicators to surgical teams was associated with concomitant reductions in major adverse events in patients

9 Nov, 2020 | 01:23h | UTC

Effect of monitoring surgical outcomes using control charts to reduce major adverse events in patients: cluster randomised trial – The BMJ


NICE Guideline: Human and animal bites. Assessment, indications for antibiotic prophylaxis in uninfected bites, and choice of antibiotic are reviewed

5 Nov, 2020 | 09:02h | UTC

Human and animal bites: antimicrobial prescribing – National Institute for Health and Care Excellence


Review: Management of common postoperative complications

4 Nov, 2020 | 09:26h | UTC

Management of Common Postoperative Complications – Mayo Clinic Proceedings


Updated guidelines to reduce venous thromboembolism in trauma patients

3 Nov, 2020 | 03:08h | UTC

Updated guidelines to reduce venous thromboembolism in trauma patients: A Western Trauma Association critical decisions algorithm – Trauma and Acute Care Surgery


Guideline: Airway management in adult trauma patients

27 Oct, 2020 | 09:30h | UTC

Western Trauma Association critical decisions in trauma: airway management in adult trauma patients – Trauma Surgery & Acute Care Open


Commentary on Twitter


Study: Low risk of SARS-CoV-2 transmission among coworkers in a surgical environment

23 Oct, 2020 | 09:05h | UTC

Risk of SARS-CoV-2 Transmission Among Coworkers in a Surgical Environment – Mayo Clinic Proceedings


Meta-analysis: Efficacy and safety of tranexamic acid in acute traumatic brain injury

22 Oct, 2020 | 09:31h | UTC

Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials – Intensive Care Medicine


Commentary on Twitter


Randomized trial: Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury

7 Oct, 2020 | 09:04h | UTC

Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial – JAMA Surgery

Commentaries: Prehospital Tranexamic Acid: STAAMP of Approval or Return to Sender? – JAMA Surgery AND Trial examines prehospital administration of blood-clotting agent in severely injured trauma patients – News Medical


Commentary on Twitter


[Abstract Only] A Randomized trial comparing antibiotics with appendectomy for appendicitis

6 Oct, 2020 | 00:44h | UTC

A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Benefits, risks seen with antibiotics-first for appendicitis – University of Washington School of Medicine

Infographic: Deciding Between Antibiotics & Surgery for Appendicitis: Findings from the CODA Study


Commentary on Twitter


Global Burden of Injury: IHME special series of 13 research articles for the Global Burden of Disease Study

4 Oct, 2020 | 23:09h | UTC

Table of Contents: Global Burden of Injuries

Editorial: Global burden of injuries: it is time to understand the data in order to intervene – Injury Prevention


Commentary on Twitter


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