General Surgery & Trauma
M-A | Incidence of multiple organ failure in adult polytrauma patients
30 Mar, 2023 | 13:30h | UTC
Practice Guidance | On-site treatment of avalanche victims
28 Mar, 2023 | 14:48h | UTC
Position Paper | Prehospital hemorrhage control and treatment by clinicians
27 Mar, 2023 | 13:20h | UTC
Phase 2b RCT | Efficacy and safety of PL-5 (Peceleganan) spray for wound infections
27 Mar, 2023 | 13:08h | UTC
Cohort Study | Association between motor vehicle crashes and adverse maternal outcomes in pregnancy
24 Mar, 2023 | 12:54h | UTCMaternal outcomes in association with motor vehicle crashes during pregnancy: a nationwide population-based retrospective study – Injury Prevention (link to abstract – full text may be available here)
News Release: Pregnant women in traffic collisions at heightened risk of birth complications – BMJ Newsroom
M-A | Efficacy of intraosseous access for trauma resuscitation
23 Mar, 2023 | 12:52h | UTC
RCT | 4F-PCC fails to reduce blood product consumption and raises thromboembolic events in trauma patients
22 Mar, 2023 | 13:41h | UTCSummary: The PROCOAG Randomized Clinical Trial aimed to investigate the efficacy and safety of 4-factor prothrombin complex concentrate (4F-PCC) in trauma patients at risk of massive transfusion. Conducted in 12 French trauma centers, this double-blind, randomized, placebo-controlled superiority trial involved 324 patients. All patients were treated according to European traumatic hemorrhage guidelines and received early ratio-based transfusion (packed red blood cells:fresh frozen plasma ratio of 1:1 to 2:1). The primary outcome measured was 24-hour blood product consumption (efficacy), while arterial or venous thromboembolic events were assessed as a secondary outcome (safety).
The trial revealed no significant difference in 24-hour blood product consumption between the 4F-PCC and placebo groups, with median consumption of 12 units and 11 units, respectively. However, the study identified a statistically significant higher risk of thromboembolic events in the 4F-PCC group, with 35% of patients experiencing at least one event compared to 24% in the placebo group.
In conclusion, the study found no beneficial effect of incorporating 4F-PCC into a ratio-based transfusion strategy for patients with severe trauma at risk of massive transfusion. Furthermore, the higher rate of thromboembolic events in the 4F-PCC group indicated potential harm. The findings do not support the routine use of 4F-PCC in patients experiencing trauma who are at risk for extensive transfusion.
Article: Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
Review | Neurogenic shock: definition, identification, and management in the ED
20 Mar, 2023 | 13:09h | UTCNeurogenic Shock: Definition, Identification, and Management in the ED – emDocs
Review | Approach to the patient with adrenal hemorrhage
15 Mar, 2023 | 15:03h | UTCApproach to the Patient With Adrenal Hemorrhage – The Journal of Clinical Endocrinology & Metabolism
Brief Review | Enhanced recovery after emergency laparotomy
13 Mar, 2023 | 14:37h | UTCEnhanced recovery after emergency laparotomy – British Journal of Surgery
New WHO guidelines to boost the use of life-saving safety restraints in vehicles
10 Mar, 2023 | 14:40h | UTCNews Release: New global guidelines to boost the use of life-saving safety restraints in vehicles – World Health Organization
Perspective | Dangerous selfies aren’t just foolish. We need to treat them like the public health hazard they really are
8 Mar, 2023 | 14:30h | UTC
E-Scooter users more likely to suffer serious trauma compared to bicycle users: a nationwide study in England and Wales
8 Mar, 2023 | 14:13h | UTCSummary:
The study aimed to determine the incidence, demographics, and injury patterns involved in E-Scooter-related hospital admissions due to significant trauma compared with bicycle-related trauma within England and Wales. The retrospective cohort study was based on data submitted to the UK Trauma Audit and Research Network (TARN) registry between 1 January 2021 to 31 December 2021.
The study found that E-Scooter users were more likely to be admitted to a major trauma center or a critical care unit than bicycle users. Serious head and limb trauma occurred more frequently among E-Scooter users, while serious chest and pelvic trauma were greater among bicycle users. Over one-third of E-Scooter injuries were incurred outside the current legislation by patients who were intoxicated by alcohol and drugs or under the age of 17.
The study suggests a greater relative incidence of serious trauma and an alternative pattern of injury among E-Scooter users compared with bicycle users. The study concludes that further legislation and tighter regulation of E-Scooter rental are required to reduce the already significant burden of injury associated with this mode of transport.
Article: Major trauma among E-Scooter and bicycle users: a nationwide cohort study – Injury Prevention
News Release: Crashing an e-scooter likely to lead to more serious injuries than crashing a bike – British Medical Journal
Commentary: E-scooter riders more likely than cyclists to sustain serious injuries – BBC
The European guideline on management of major bleeding and coagulopathy following trauma
2 Mar, 2023 | 13:04h | UTC
Guidelines | Efficacy and safety of non-steroidal anti-inflammatory drugs for the treatment of acute pain after orthopedic trauma
28 Feb, 2023 | 13:48h | UTC
RCT | Single chest tube superior to double chest tube post decortication in trauma/TB patients
27 Feb, 2023 | 12:53h | UTC
Consensus Paper | Early management of isolated severe traumatic brain injury in a hospital without neurosurgical capabilities
24 Feb, 2023 | 13:49h | UTC
Commentary from the author on Twitter
Great to see our consensus published. Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES).https://t.co/k9hwI82dOW pic.twitter.com/pIp5gFRnPa
— Deepak Sharma (@deepak_neuro) January 14, 2023
Review | Management of gastrointestinal foreign bodies with brief review of the guidelines
24 Feb, 2023 | 13:36h | UTC
Instant noodle burns common in pediatric scald injuries: Study highlights need for prevention efforts
21 Feb, 2023 | 11:50h | UTCSummary: The study examined pediatric scald burns at the University of Chicago Burn Center between 2010 and 2020 and found that 31% of burns were attributed to instant noodles. Children with instant noodle burns were typically older, more likely to be Black/African American, and from lower socio-economic backgrounds. They were also more likely to be unsupervised at the time of the injury. While instant noodle burns were smaller and required less operative intervention than other scald burns, some still required hospitalization and were associated with complications. The study highlights the need for targeted burn prevention efforts to reduce the incidence of these common but serious injuries.
Article: Pediatric instant noodle burns: A ten-year single center retrospective study – Burns (link to abstract – $ for full-text)
Commentary: Why Instant Noodles Are a Danger to Your Kids – HealthDay
Consensus Paper | Pediatric traumatic hemorrhagic shock
17 Feb, 2023 | 13:15h | UTCPreface: Pediatric traumatic hemorrhagic shock consensus conference
Other articles in the supplement:
Pediatric traumatic hemorrhagic shock consensus conference research priorities
Building an optimal pediatric trauma program
Time is tissue: Barriers to timely transfusion after pediatric injury
Resuscitative practices and the use of low-titer group O whole blood in pediatric trauma
Tranexamic acid in pediatric hemorrhagic trauma
Blood banking considerations in pediatric trauma
Detecting traumatic brain injury–induced coagulopathy: What we are testing and what we are not
Consensus Statement | Development of an Enhanced Recovery After Surgery (ERAS) surgical safety checklist
10 Feb, 2023 | 14:03h | UTC
Commentary from the author on Twitter (thread – click for more)
The @WHO Surgical Safety Checklist and the @ErasSociety guidelines come together.🔥
#ERAS teams can leverage 2 tools in 1 to improve care in critical perioperative communication moments https://t.co/EaXYyj7b56
via @JAMANetworkOpen part of @JAMANetwork pic.twitter.com/WHJMjThubO— Mary Brindle (@MaryEBrindle) February 8, 2023
RCT | Tissue adhesive, adhesive tape, and sutures for skin closure of pediatric surgical wounds
9 Feb, 2023 | 13:35h | UTC
Spinal cord injury: the global incidence, prevalence, and disability from the Global Burden of Disease Study 2019
9 Feb, 2023 | 13:20h | UTCCommentary: Measures needed to combat growing incidence and burden of spinal cord injury – Spinal News International
Guideline | Assessment and management of complex fractures
7 Feb, 2023 | 14:19h | UTCFractures (complex): assessment and management – National Institute for Health and Care Excellence
ACG Guideline | Management of patients with acute lower gastrointestinal bleeding
6 Feb, 2023 | 13:43h | UTCManagement of Patients With Acute Lower Gastrointestinal Bleeding: An Updated ACG Guideline
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