Tropical Medicine
WHO approves first ever malaria vaccine for children at risk.
7 Oct, 2021 | 10:40h | UTCWHO recommends groundbreaking malaria vaccine for children at risk – World Health Organization
Commentaries:
WHO Approves First Ever Malaria Vaccine – Health Policy Watch
In major decision, WHO recommends broad rollout of world’s first malaria vaccine – STAT
Why the WHO approval of the first malaria vaccine is a big deal – Vox
WHO greenlights the world’s first malaria vaccine — but it’s not a perfect shot – NPR
The World Health Organization Just Endorsed The World’s First Malaria Vaccine – TIME
WHO Backs Widespread Use Of First Malaria Vaccine – Forbes
World’s 1st malaria vaccine recommended by WHO – LiveScience
Commentaries on Twitter
I started my career as a #malaria researcher, and I longed for the day that we would have an effective vaccine against this ancient and terrible disease. Today is that day: @WHO is recommending the broad use of the world’s first malaria vaccine. #EndMalaria https://t.co/Oh1O155tYj
— Tedros Adhanom Ghebreyesus (@DrTedros) October 6, 2021
(thread – click for more)
A child dies from #malaria every two minutes.
One death is one too many.🚨 Today, WHO recommends RTS,S, a groundbreaking malaria vaccine, to reduce child illness & deaths in areas with moderate and high malaria transmission https://t.co/xSk58nTIV1#VaccinesWork pic.twitter.com/mSECLtRhQs
— World Health Organization (WHO) (@WHO) October 6, 2021
Systematic Review: Administration of antimalarial drugs to whole populations for reducing malaria.
7 Oct, 2021 | 10:36h | UTCAdministration of antimalarial drugs to whole populations for reducing malaria – Cochrane Library
Original study: Mass drug administration for malaria – Cochrane Library
Commentary on Twitter
Administration of #antimalarial drugs to whole populations for reducing #malaria – https://t.co/4Q4vGKwmgU – Updated #OpenAccess @Cochrane_IDG review includes 13 studies and gives implications for practice & future research. pic.twitter.com/EMB2Tihs81
— Cochrane UK (@CochraneUK) October 3, 2021
Drug-resistant malaria is gaining a foothold in Africa – “Analyses of patient blood samples suggest artemisinin effectiveness is slipping”.
28 Sep, 2021 | 08:49h | UTCDrug-resistant malaria is gaining a foothold in Africa – Science
Commentary on Twitter
Drug-evading parasites appeared in Southeast Asia in the early 2000s, eventually leading to failures of key therapies.
But the stakes are higher for Africa, home to 94% of both malaria cases and deaths worldwide in 2019. https://t.co/ILamXKP3yh
— Global Health NOW (@ghn_news) September 27, 2021
How COVID is derailing the fight against HIV, TB and malaria.
15 Sep, 2021 | 09:01h | UTCHow COVID is derailing the fight against HIV, TB and malaria – Nature
Related:
How COVID hurt the fight against other dangerous diseases
World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis
An update on prevention of malaria in travelers.
15 Sep, 2021 | 08:39h | UTCAn update on prevention of malaria in travelers – Therapeutic Advances in Infectious Disease
Related: CDC Yellow Book
RCT: Severe malaria among young African children dramatically reduced through seasonal vaccination and preventative drug combination.
1 Sep, 2021 | 09:02h | UTCOriginal article: Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention – New England Journal of Medicine
Commentary: Malaria trial shows ‘striking’ 70% reduction in severe illness in children – The Guardian
Related: Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal
Cluster RCT: Vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh conferred 85% total protection.
11 Aug, 2021 | 08:28h | UTCInvited commentary: Salmonella Typhi Vi polysaccharide conjugate vaccine protects infants and children against typhoid fever – The Lancet
Diagnosis and clinical management of hepatosplenic schistosomiasis: A scoping review of the literature.
15 Jul, 2021 | 09:02h | UTC
CDC advisory panel backs use of dengue vaccine in high-risk areas, despite delivery challenges.
25 Jun, 2021 | 10:13h | UTC
WHO issues new guidance for research on genetically modified mosquitoes to fight malaria and other vector-borne diseases.
10 Jun, 2021 | 09:38h | UTCGuideline: The guidance framework for testing genetically modified mosquitoes – World Health Organization
Cluster-randomized trial: Wolbachia-infected Aedes aegypti (less susceptible than wild-type A. aegypti to dengue virus infection) deployments reduced the incidence of symptomatic dengue and resulted in fewer hospitalizations.
10 Jun, 2021 | 09:40h | UTCCommentary: ‘Miraculous’ mosquito hack cuts dengue by 77% – BBC
Video Abstract: Efficacy of Wolbachia-infected Mosquito Deployments for the Control of Dengue
Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal
25 Apr, 2021 | 21:17h | UTCNews release: Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal – University of Oxford
Original study (preprint): High Efficacy of a Low Dose Candidate Malaria Vaccine, R21 in 1 Adjuvant Matrix-M™, with Seasonal Administration to Children in Burkina Faso – The Lancet
Commentaries: Malaria vaccine hailed as potential breakthrough – BBC AND Oxford Malaria vaccine proves highly effective in Burkina Faso trial – The Guardian
Commentary on Twitter (thread – click for more)
💡AMAZING—First high >75% efficacy vaccine for a disease with 229 million cases & 409,000 deaths worldwide in 2019 —#Malaria!
Created by Oxford, produced by Serum Institute of India, & supporting adjuvant by Novavax, SII expects to make 200 mil doses a year!
Science! #vaccine pic.twitter.com/gnPMvXxww6
— Eric Feigl-Ding (@DrEricDing) April 23, 2021
Ahead of World Malaria Day, WHO launches effort to stamp out malaria in 25 more countries by 2025
22 Apr, 2021 | 08:23h | UTCReport: Zeroing in on malaria elimination: Final report of the E-2020 initiative – World Health Organization
How COVID hurt the fight against other dangerous diseases
22 Apr, 2021 | 08:35h | UTCHow COVID hurt the fight against other dangerous diseases – Nature
Related: World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis AND WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1
RCT: New shorter regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease
8 Apr, 2021 | 08:47h | UTC
Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease
5 Apr, 2021 | 01:05h | UTC
Commentary on Twitter
In this report from the Democratic Republic of Congo, Ebola virus disease developed in a young man, and he recovered after treatment with a monoclonal antibody.
6 months later, EVD recrudesced, and he transmitted the virus to others & died from EVD @NEJM https://t.co/kJSBNdN5bC pic.twitter.com/jDnnGMLmOG— Antibiotic Steward🆔🦠Bassam Ghanem (@ABsteward) March 31, 2021
Diagnosis and clinical management of hepatosplenic schistosomiasis: A scoping review of the literature
31 Mar, 2021 | 03:01h | UTC
Resurgence of Ebola Virus disease in Guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days
14 Mar, 2021 | 20:15h | UTCCommentaries: Bombshell analysis traces new Ebola outbreak to survivor of West Africa crisis – STAT AND New Ebola outbreak likely sparked by a person infected 5 years ago – Science AND Ebola survivors can pass on the virus: we’re trying to understand what role sex plays – The Conversation AND The latest Ebola outbreak may have started with someone infected years ago – Science News
WHO Guidance: Management of people affected by lymphatic filariasis
7 Mar, 2021 | 19:26h | UTC
Systematic review: Atovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria
5 Mar, 2021 | 08:13h | UTCAtovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library
Targeted spraying to prevent malaria in low-transmission setting halves cost of current practice
28 Feb, 2021 | 21:25h | UTCNews release: Targeted spraying to prevent malaria in low-transmission setting halves cost of current practice – Wits University
Commentary on Twitter
New paper from @davidjbath @CatKPitt and colleagues @LSHTM_CHIL @LSHTM_malaria
Targeting spraying for malaria control is safe, less costly, and cost-effective compared with standard spraying
With low incidence, these funds could be spent elsewhere🦟https://t.co/OCb9qhqBCX https://t.co/a0sD4uhymo
— Centre for Health Economics In London (CHIL) (@LSHTM_CHIL) February 26, 2021
Turning houses into ‘lethal mosquito lures’ nearly halves incidence of malaria in children
28 Feb, 2021 | 21:26h | UTC
Commentary on Twitter (thread – click for more)
Incredibly pleased to finally be able to share this with the world @PSUScience @LSHTM @LSTMnews
Impact and cost-effectiveness of a lethal house lure against malaria transmission in central Côte d'Ivoire: a two-arm, cluster-randomised controlled trialhttps://t.co/aPkvtHMDSS
— Eleanore Sternberg (@EDSternberg) February 25, 2021
Clinical Update: Enteric Fever
28 Feb, 2021 | 21:02h | UTCEnteric fever – The BMJ (free for a limited period)
Commentary on Twitter
Diagnosis of enteric fever is complicated as symptoms overlap with other causes of fever and early investigations are inconclusive. Here's what you need to know about its presentation, diagnosis, and treatment #BMJEducationhttps://t.co/1mvbNb7peS pic.twitter.com/Z7YxngHanl
— The BMJ (@bmj_latest) February 28, 2021
M-A: Risk predictors of progression to severe disease during the febrile phase of dengue
28 Feb, 2021 | 20:57h | UTC
Global guideline for the diagnosis and management of rare mold infections
19 Feb, 2021 | 02:18h | UTC
Commentary on Twitter
🔥🔥🔥 Global Guideline for Rare Moulds. Endorsed by 55 scientific societies in the field.
All you need to know about Diagnosis and Treatment of Rare Mould infections: from Fusarium to Purpureocillium. @eurconfmedmycol @ISHAM_Mycology @ASMicrobiology
https://t.co/YJ3BX58osW pic.twitter.com/nrAGZl5ox4— Martin Hoenigl (@martinhoenigl) February 16, 2021