Critical Care & Emergencies
Observational Study: Many Patients with Covid-19 in the ICU Develop Thromboembolism Despite Routine Prophylaxis
29 May, 2020 | 03:17h | UTC
WHO Interim Guidance: Clinical Management of COVID-19
28 May, 2020 | 10:02h | UTCClinical management of COVID-19 – World Health Organization
Systematic Review: Hydroxychloroquine or Chloroquine for Treatment or Prophylaxis of COVID-19
28 May, 2020 | 09:59h | UTC
Remdesivir for Covid-19: A 5-day Course is Similarly Effective as a 10-day Course
28 May, 2020 | 10:00h | UTCRemdesivir for 5 or 10 Days in Patients with Severe Covid-19 – New England Journal of Medicine
Study: No Evidence Blanket ‘Do-not-resuscitate’ Orders for COVID-19 Patients are Necessary
28 May, 2020 | 09:50h | UTC
Just the Facts: What Drugs are Safe and Effective for COVID-19?
27 May, 2020 | 02:31h | UTCRelated Guidelines: NIH Coronavirus Disease 2019 (COVID-19) Treatment Guidelines – National Institutes of Health AND Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection
“Apart from supportive care, there are no current effective therapeutics for COVID-19”
Clinical Guidance: Advanced Pulmonary and Cardiac Support of COVID-19 Patients
27 May, 2020 | 02:27h | UTC
Meta-analysis: Efficacy and Safety of Convalescent Plasma for Severe COVID-19
27 May, 2020 | 02:21h | UTC
Duration of Prone Position Sessions: A Prospective Cohort Study
27 May, 2020 | 02:20h | UTCDuration of prone position sessions: a prospective cohort study – Annals of Intensive Care
Meta-Analysis: Vasopressin or Its Analogs are Not Associated with Reduced Mortality Compared to Catecholamines Alone in Patients with Septic Shock
27 May, 2020 | 02:13h | UTCRelated Review: Vasopressin and its analogues in shock states: a review – Annals of Intensive Care (free)
Review: COVID-19 and Cardiovascular Disease
26 May, 2020 | 10:05h | UTCCOVID-19 and Cardiovascular Disease – Circulation
Related Guidelines: COVID-19 rapid guideline: acute myocardial injury – National Institute for Health and Care Excellence AND ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic – European Society of Cardiology AND Management of Acute Myocardial Infarction During the COVID-19 Pandemic – Journal of the American Academy of Cardiology
Podcast: Evidence-Based Medicine for the Management of COVID-19 ARDS
26 May, 2020 | 09:57h | UTCRelated Perspective from the Author: In Defense of Evidence-Based Medicine for the Treatment of COVID-19 ARDS – Annals of the American Thoracic Society
Clinical Guidance: Intravenous Fluid Therapy in the Perioperative and Critical Care Setting
26 May, 2020 | 09:28h | UTC
Remdesivir for the Treatment of Covid-19 — Preliminary Report
25 May, 2020 | 02:06h | UTCRemdesivir for the Treatment of Covid-19 — Preliminary Report – New England Journal of Medicine
Commentaries: Preliminary report on NIAID trial of remdesivir – PulmCrit AND Peer-reviewed data shows remdesivir for COVID-19 improves time to recovery – National Institutes of Health AND Covid-19 study details benefits of treatment with remdesivir, and also its limitations – STAT
Related Commentary on Twitter (Thread – Click for more)
I finished reading the Remdesivir trial
If you want my thoughts you will have to read this thread
[Thread] pic.twitter.com/GqA30lCOLI
— Vinay Prasad (@VPrasadMDMPH) May 23, 2020
Hydroxychloroquine and Chloroquine for Covid-19: Large Observational Analysis Finds No Benefit and Possible Harm
25 May, 2020 | 02:03h | UTCCommentaries: Chloroquine or hydroxychloroquine for COVID-19: why might they be hazardous? – The Lancet AND What a big new study on malaria drugs as Covid-19 treatments tells us — and what it doesn’t – STAT AND Hydroxychloroquine May Cause More Harm Than Benefit To COVID-19 Patients, Says New Lancet Study – Health Policy Watch
Meta-Analysis: Corticosteroids May Reduce Mortality for Patients with COVID-19 and ARDS
25 May, 2020 | 01:45h | UTC
Clinical Guidance: Thromboembolism and Anticoagulant Therapy During the COVID-19 Pandemic
25 May, 2020 | 01:43h | UTCRelated: Coagulation abnormalities and thrombosis in patients with COVID-19 – The Lancet AND COVID-19 and its implications for thrombosis and anticoagulation – Blood AND Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Infection: A Consensus Statement before Guidelines – Thrombosis and Haemostasis AND Thrombosis and COVID-19: FAQs For Current Practice – American College of Cardiology
Systematic Review: Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19
25 May, 2020 | 01:40h | UTC
[Abstract Only] Randomized Trial: Haloperidol Effective for the Treatment of Headache in the Emergency Department
25 May, 2020 | 01:33h | UTC
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
22 May, 2020 | 04:59h | UTCCommentary: Lungs of deceased COVID-19 patients show distinctive features – Brigham and Women’s Hospital
Related: Postmortem Examination of Patients With COVID-19 – JAMA AND Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome: Results From a Prospective, Single-Center, Clinicopathologic Case Series – Annals of Internal Medicine AND Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis
Choosing Wisely in the COVID-19 Era: Preventing Harm to Healthcare Workers
22 May, 2020 | 04:58h | UTC
SARS2-CoV-2 and Stroke in a New York Healthcare System
22 May, 2020 | 04:56h | UTCSARS2-CoV-2 and Stroke in a New York Healthcare System – Stroke
Commentary: COVID-19 patients may have lower stroke rates than previously suggested – NYU Grossman School of Medicine
15 Drugs Being Tested to Treat COVID-19 and How They Would Work
22 May, 2020 | 04:52h | UTC15 drugs being tested to treat COVID-19 and how they would work – Nature
[Preprint] IL6 Inhibition in Critically Ill COVID-19 Patients is Associated with Increased Secondary Infections
22 May, 2020 | 04:44h | UTC
Wide Complex Tachycardia Differentiation: A Reappraisal of the State‐of‐the‐Art
22 May, 2020 | 04:38h | UTC