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Critical Care & Emergencies

Comprehensive review on the management of pharmaceutical and recreational drug poisoning

1 Dec, 2020 | 08:21h | UTC

Management of pharmaceutical and recreational drug poisoning – Annals of Intensive Care

 

NICE COVID-19 guideline: Prevention of thromboembolism in patients with COVID-19. “For patients who are having advanced respiratory support: consider increasing pharmacological VTE prophylaxis to an intermediate dose”

1 Dec, 2020 | 08:19h | UTC

COVID-19 rapid guideline: reducing the risk of venous thromboembolism in over 16s with COVID-19 – National Institute for Health and Care Excellence

 

Colchicine to be investigated as a possible treatment for COVID-19 in the RECOVERY trial

1 Dec, 2020 | 08:08h | UTC

Colchicine to be investigated as a possible treatment for COVID-19 in the RECOVERY trial – University of Oxford

Commentary: Gout drug Colchicine to be tested as COVID-19 treatment in UK trial – Reuters

 

Critically ill patients with COVID-19: A narrative review on prone position

1 Dec, 2020 | 08:07h | UTC

Critically Ill Patients with COVID-19: A Narrative Review on Prone Position – Pulmonary Therapy

 

Randomized trial: Convalescent Plasma does not improve clinical status or overall mortality in severe Covid-19 pneumonia

25 Nov, 2020 | 09:17h | UTC

A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia – New England Journal of Medicine

Commentary: New trial of convalescent plasma for covid-19 falls flat, another setback for hyped treatment – Brief19

 

Commentary on Twitter

 

Latest COVID-19 guidelines come out against bamlanivimab, remdesivir

25 Nov, 2020 | 09:10h | UTC

Latest COVID-19 guidelines come out against bamlanivimab, remdesivir – ACP Internist

 

Diagnosis, management, and pathophysiology of arterial and venous thrombosis in COVID-19

24 Nov, 2020 | 09:34h | UTC

Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19 – JAMA

 

Commentary on Twitter

 

Data show hospitalized Covid-19 patients are surviving at higher rates, but surge in cases could roll back gains

24 Nov, 2020 | 09:25h | UTC

Data show hospitalized Covid-19 patients are surviving at higher rates, but surge in cases could roll back gains – STAT

 

Updated WHO guideline on drugs for Covid-19 rejects Remdesivir and strongly recommends Corticosteroids for patients with severe and critical disease

20 Nov, 2020 | 08:51h | UTC

A living WHO guideline on drugs for covid-19 – The BMJ

Commentary: WHO Guideline Development Group advises against use of remdesivir for COVID-19 – British Medical Journal

 

Commentary on Twitter

 

Older adults with COVID-19 commonly present to the ED with delirium

20 Nov, 2020 | 08:46h | UTC

Delirium in Older Patients With COVID-19 Presenting to the Emergency Department – JAMA Network Open

Commentaries: Delirium could signal Covid-19 infection in older adults, study finds – STAT AND Delirium fairly common in older COVID-19 patients – CIDRAP AND Delirium is first symptom for many elderly COVID-19 patients – UPI

 

Commentary on Twitter

 

Systematic review: Routine laboratory tests are not useful for accurately ruling in or ruling out COVID-19 on their own

20 Nov, 2020 | 08:42h | UTC

Routine laboratory testing to determine if a patient has COVID‐19 – Cochrane Library

Summary: Routine laboratory testing to determine if a patient has COVID‐19 – Cochrane Library

 

Review: How to ventilate obstructive and asthmatic patients

20 Nov, 2020 | 08:39h | UTC

How to ventilate obstructive and asthmatic patients – Intensive Care Medicine

 

Commentary on Twitter

 

NICE Guideline: Acute coronary syndromes

19 Nov, 2020 | 09:24h | UTC

Acute coronary syndromes – National Institute for Health and Care Excellence

Visual summary: STEMI

Visual summary: NSTEMI/unstable angina

Visual summary: Cardiac rehabilitation and secondary prevention

 

Review: Fluid administration and monitoring in ARDS. Restrictive vs. liberal strategy of fluid administration, assessment of fluid responsiveness, and other topics are discussed

19 Nov, 2020 | 09:19h | UTC

Fluid administration and monitoring in ARDS: which management? – Intensive Care Medicine

 

Commentary on Twitter

 

CDC Report: 9% readmitted after Covid-19 hospitalization. Risk factors were age ≥65 y, chronic medical conditions, recent hospitalization before Covid-19, and discharge to a skilled nursing facility or with home health care

17 Nov, 2020 | 09:46h | UTC

Characteristics of Hospitalized COVID-19 Patients Discharged and Experiencing Same-Hospital Readmission — United States, March–August 2020 – CDC Morbidity and Mortality Weekly Report

Commentary: 9 percent readmitted after index COVID-19 hospitalization – MedicalXpress AND One in 11 coronavirus patients discharged from a hospital is readmitted within two months, suggesting long-lasting effects of the infection, CDC report warns – Daily Mail

 

Commentary on Twitter

 

Review: Prone positioning for patients with hypoxic respiratory failure related to COVID-19

17 Nov, 2020 | 09:41h | UTC

Prone positioning for patients with hypoxic respiratory failure related to COVID-19 – Canadian Medical Association Journal

 

Commentary on Twitter

 

Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies

17 Nov, 2020 | 09:40h | UTC

Treatment of Community-Acquired Pneumonia in Immunocompromised Adults: A Consensus Statement Regarding Initial Strategies – CHEST

Editorial: Management of Community-Acquired Pneumonia in Immunocompromised Adults – CHEST

 

Systematic review: Evidence-based practices for acute respiratory failure and Acute Respiratory Distress Syndrome

17 Nov, 2020 | 09:37h | UTC

Evidence-Based Practices for Acute Respiratory Failure and Acute Respiratory Distress Syndrome – CHEST

Commentary: Best practices for mechanical ventilation in patients with ARDS, COVID-19 – University of Michigan

 

Podcast on Wilderness Medicine: Pearls on altitude sickness, frostbite, animal bites, thermoregulation, and wound care

17 Nov, 2020 | 09:32h | UTC

#242 Wilderness Medicine: Prepare for Disaster – The Curbsiders Internal Medicine Podcast

 

#AHA20 – A small phase 2 randomized trial showed significantly improved survival with an early ECMO-facilitated resuscitation for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation

16 Nov, 2020 | 01:56h | UTC

Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial – The Lancet

Commentaries: Early ECMO-Facilitated Resuscitation for Out-of-Hospital Cardiac Arrest – NEJM Journal Watch AND Advanced REperfusion STrategies for refractory cardiac arrest – ARREST – American College of Cardiology AND Cardiac arrest treatment that uses life support machine boosts survival – NIH News Releases

 

Commentary on Twitter

 

#AHA20 – In patients hospitalized for heart failure with iron deficiency, intravenous Ferric carboxymaltose at discharge reduced the risk of heart failure rehospitalizations

16 Nov, 2020 | 01:53h | UTC

Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial – The Lancet

Commentaries: Intravenous iron reduced rehospitalization risk in people with heart failure – American Heart Association AND AFFIRM-AHF: IV Iron Supplementation Linked to Fewer Repeat Hospitalizations for HF – TCTMD

 

Commentary on Twitter

 

Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

13 Nov, 2020 | 09:35h | UTC

Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial – JAMA

Editorial: COVID-19 Infection—Preventing Clinical Deterioration

Commentary: Fluvoxamine may prevent serious illness in COVID-19 patients, study suggests – Washington University School of Medicine

 

Covid-19: Inhaled Nebulized Interferon Beta-1a shows potential for hospitalized patients in preliminary trial

13 Nov, 2020 | 09:33h | UTC

Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial – The Lancet Respiratory Medicine

 

Case report: Persistence and evolution of SARS-CoV-2 in an immunocompromised host

13 Nov, 2020 | 09:24h | UTC

Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host – New England Journal of Medicine

 

Commentary on Twitter (thread – click for more)

 

Tranexamic acid after traumatic brain injury: Exploratory analysis combining data from CRASH-2 and CRASH-3 trials suggests reduced mortality

13 Nov, 2020 | 09:21h | UTC

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial – Critical Care

Commentary: New analysis combining data from the world’s largest trauma trials provides compelling evidence that rapid tranexamic acid treatment saves lives – London School of Hygiene & Tropical Medicine

 

Commentary on Twitter

 

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