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Emergency Medicine

AHA/ASA Guideline for the management of patients with aneurysmal subarachnoid hemorrhage

29 May, 2023 | 11:16h | UTC

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke

Top Things to Know: 2023 Aneurysmal Subarachnoid Hemorrhage Guideline – American Heart Association

 

Commentary on Twitter

 


M-A | Hydrocortisone shows no significant impact on 90-day mortality in septic shock patients

29 May, 2023 | 11:06h | UTC

Patient-Level Meta-Analysis of Low-Dose Hydrocortisone in Adults with Septic Shock – NEJM Evidence

News Release: Study examines the role of hydrocortisone in the management of adult patients with septic shock – University of California San Francisco Medical Center/News Medical

 


Guideline | Investigation and management of acute transfusion reactions

29 May, 2023 | 11:02h | UTC

Guideline on the investigation and management of acute transfusion reactions – British Journal of Haematology

 


ISPD Catheter-related infection recommendations

29 May, 2023 | 11:00h | UTC

ISPD Catheter-related Infection Recommendations: 2023 Update – Peritoneal Dialysis International

 


Guideline | Targeted temperature management in intracerebral, subarachnoid hemorrhage and acute ischemic stroke

29 May, 2023 | 10:48h | UTC

Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: updated consensus guideline recommendations by the Neuroprotective Therapy Consensus Review (NTCR) group – British Journal of Anaesthesia

 


2023 Update on sepsis and septic shock in adult patients | Management in the emergency department

25 May, 2023 | 11:26h | UTC

2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department – Journal of Clinical Medicine

 


Guideline | Assessment and early management of head injury

23 May, 2023 | 13:11h | UTC

Head injury: assessment and early management – NICE

Commentary: NICE head injury guidelines 2023: Now who do we scan? – St Emilyn’s

 


Practice Guidance | Differential diagnosis of suspected COPD exacerbations in the acute care setting

15 May, 2023 | 13:26h | UTC

Differential Diagnosis of Suspected Chronic Obstructive Pulmonary Disease Exacerbations in the Acute Care Setting: Best Practice – American Journal of Respiratory and Critical Care Medicine

 

Commentary on Twitter

 


Guideline | Acute dizziness and vertigo in the emergency department

15 May, 2023 | 13:25h | UTC

Guidelines for reasonable and appropriate care in the emergency department 3 (GRACE-3): Acute dizziness and vertigo in the emergency department – Academic Emergency Medicine

News Release: New guideline for treatment of acute dizziness and vertigo in the emergency department – Society for Academic Emergency Medicine

 


RCT | Prophylactic antibiotics show no statistically significant survival improvement in severe alcohol-related hepatitis

15 May, 2023 | 13:21h | UTC

Summary: This multicenter, randomized, double-blind clinical trial aimed to determine the efficacy of amoxicillin-clavulanate combined with prednisolone compared to placebo combined with prednisolone on mortality in patients hospitalized with severe alcohol-related hepatitis. The study involved 284 patients from 25 centers in France and Belgium with biopsy-proven severe alcohol-related hepatitis, who were followed up for 180 days.

The primary outcome was all-cause mortality at 60 days, while secondary outcomes included mortality at 90 and 180 days, infection rates, hepatorenal syndrome, and changes in Model for End-stage Liver Disease (MELD) and Lille scores. The results showed no statistically significant difference in 60-day mortality between the two groups, with 17.3% in the amoxicillin-clavulanate group and 21.3% in the placebo group. However, infection rates at 60 days were significantly lower in the amoxicillin-clavulanate group compared to the placebo group.

It is worth noting that the study may have been underpowered, as the absolute risk difference of 4% did not achieve statistical significance. In conclusion, the combination of amoxicillin-clavulanate and prednisolone did not show a statistically significant improvement in 2-month survival in patients hospitalized with severe alcohol-related hepatitis compared to prednisolone alone. These findings do not support the use of prophylactic antibiotics to improve survival in this patient population, but the potential underpowered nature of the study should be considered.

Article: Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Brief Review | Coagulation support during perioperative bleeding management

15 May, 2023 | 13:01h | UTC

Coagulation support during perioperative bleeding management – Intensive Care Medicine

 

Commentary on Twitter

 


M-A | Endovascular therapy for stroke presenting beyond 24 hours

12 May, 2023 | 13:44h | UTC

Endovascular Therapy for Stroke Presenting Beyond 24 Hours: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Should my elderly hospitalized patient with acute onset of altered mental status undergo stat head CT?

12 May, 2023 | 13:38h | UTC

Should my elderly hospitalized patient with acute onset of altered mental status undergo stat head CT? – Cleveland Clinic Journal of Medicine

 


Review | Progress in the treatment of acute pulmonary embolism and chronic thrombo-embolic pulmonary hypertension/disease

12 May, 2023 | 13:24h | UTC

Progress in the treatment of acute pulmonary embolism and chronic thrombo-embolic pulmonary hypertension/disease – European Heart Journal Supplements

See all articles in the series here

 


Review | Takotsubo syndrome: more frequent in women, more dangerous in men

12 May, 2023 | 13:21h | UTC

Takotsubo syndrome: more frequent in women, more dangerous in men – European Heart Journal Supplements

See all articles in the series here


A review of bicarbonate use in common clinical scenarios

11 May, 2023 | 12:17h | UTC

A Review of Bicarbonate Use in Common Clinical Scenarios – The Journal of Emergency Medicine

 


Review | Diagnosis and management of cirrhosis and its complications

10 May, 2023 | 16:06h | UTC

Diagnosis and Management of Cirrhosis and Its Complications: A Review – JAMA (free for a limited period)

Author Interview: Management of Cirrhosis in 2023

 


ESTES recommendation on thoracolumbar spine fractures

10 May, 2023 | 15:40h | UTC

ESTES recommendation on thoracolumbar spine fractures – European Journal of Trauma and Emergency Surgery


M-A | PCI vs. CABG in non–ST-elevation coronary syndromes and multivessel disease

10 May, 2023 | 15:35h | UTC

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Non–ST-Elevation Coronary Syndromes and Multivessel Disease: A Systematic Review and Meta-Analysis – American Journal of Cardiology

 


Guideline | Management of type B aortic dissection

10 May, 2023 | 15:32h | UTC

Interdisciplinary German clinical practice guidelines on the management of type B aortic dissection – Gefässchirurgie

 


M-A | Clinical profile and outcome of isolated pulmonary embolism

10 May, 2023 | 15:27h | UTC

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis – eClinicalMedicine

 


Cohort Study | Predicting the emergence of malignant brain edema in acute ischemic stroke

10 May, 2023 | 15:26h | UTC

Predicting the emergence of malignant brain oedema in acute ischaemic stroke: a prospective multicentre study with development and validation of predictive modelling – eClinicalMedicine

 


Study shows unenhanced CT shows 30% lower diagnostic accuracy in abdominal pain evaluation

9 May, 2023 | 15:02h | UTC

Diagnostic Accuracy of Unenhanced Computed Tomography for Evaluation of Acute Abdominal Pain in the Emergency Department – JAMA Surgery (free for a limited period)

Editorial: Intravenous Contrast in Computed Tomography Imaging for Acute Abdominal Pain – JAMA Surgery (free for a limited period)

News Release: Bypassing contrast in patients with kidney disease and contrast allergies may lead to less accurate scans – University of Michigan

Commentary: New data suggest clinicians should think twice before foregoing contrast-enhanced imaging – Health Imaging

 

Commentary on Twitter

 


Review | Challenges in cardiology: diagnosis of native and prosthetic valve endocarditis

9 May, 2023 | 14:19h | UTC

Challenges in cardiology: diagnosis of native and prosthetic valve endocarditis – European Heart Journal Supplements

See all articles in the series here

 


Review | Causes of sudden death

9 May, 2023 | 14:16h | UTC

Causes of sudden death – European Heart Journal Supplements

See all articles in the series here

 


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