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Emergency Medicine

Comprehensive Review | Pneumonia

9 Apr, 2021 | 03:14h | UTC

Pneumonia – Nature Reviews Disease Primers (free for a limited period)

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Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19

12 Apr, 2021 | 01:24h | UTC

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial – The Lancet Respiratory Medicine

Commentary: Early treatment with inhaled budesonide to prevent clinical deterioration in patients with COVID-19 – The Lancet Respiratory Medicine

 

Commentary on Twitter

 


[Preprint] CoronaVac is 50% effective for reducing symptomatic SARS-CoV-2 infection after the first dose in the setting of high P.1 variant transmission in Brazil

9 Apr, 2021 | 03:36h | UTC

Effectiveness of CoronaVac in the setting of high SARS-CoV-2 P.1 variant transmission in Brazil: A test-negative case-control study – medRxiv

 

Commentary on Twitter (thread – click for more)

 


The NIH COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19

9 Apr, 2021 | 03:35h | UTC

The COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19 – NIH COVID-19 Treatment Guidelines

 


Commentary | Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes?

9 Apr, 2021 | 03:28h | UTC

Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology

 


Study finds low risk of venous thromboembolism in outpatients with Covid-19 – researchers advise against the use of anticoagulants outside clinical trials

8 Apr, 2021 | 08:59h | UTC

Incidence of 30-Day Venous Thromboembolism in Adults Tested for SARS-CoV-2 Infection in an Integrated Health Care System in Northern California – JAMA Internal Medicine

Commentaries: VTE Related to SARS-CoV-2 Infection Less Of a Problem in Outpatients – TCTMD AND No Increase Seen in Outpatient VTE for SARS-CoV-2-Positive Patients – Physician’s Weekly

 

Commentary on Twitter (thread – Click for more)

 


ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

6 Apr, 2021 | 01:12h | UTC

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Summary for Patients: Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians

News release: ACP best practice advice: Shorter course of antibiotics may be appropriate for some common infection – American College of Physicians

 


Guidance on syndrome of Thrombosis and Thrombocytopenia occurring after coronavirus Vaccination

7 Apr, 2021 | 01:48h | UTC

Guidance produced from the Expert Haematology Panel (EHP) focussed on syndrome of Thrombosis and Thrombocytopenia occurring after coronavirus Vaccination – British Society of Haematology

Related: Exceedingly rare side effects reported with AstraZeneca vaccine in the UK – 22 cases of cerebral venous sinus thrombosis with low levels of platelets out of 18 million vaccinated individuals

 

Commentary on Twitter

 


Large study showed no association between blood group types and increased risk of Covid-19

7 Apr, 2021 | 01:41h | UTC

Association of Sociodemographic Factors and Blood Group Type With Risk of COVID-19 in a US Population – JAMA Network Open

 

Commentary on Twitter

 


Diagnostic Test Interpretation: Evaluation of Hypokalemia

6 Apr, 2021 | 01:07h | UTC

Evaluation of Hypokalemia – JAMA (free for a limited period)

 


M-A: Colchicine administration for percutaneous coronary intervention

6 Apr, 2021 | 00:58h | UTC

Colchicine administration for percutaneous coronary intervention: A meta-analysis of randomized controlled trials – The American Journal of Emergency Medicine (link to abstract – $ for full-text)

Related: Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials – European Heart Journal (link to abstract – $ for full-text)

 


Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates

5 Apr, 2021 | 01:52h | UTC

Mortality and Readmission Rates Among Patients With COVID-19 After Discharge From Acute Care Setting With Supplemental Oxygen – JAMA Network Open

Video: Home Oxygen Instructions for Discharged Patients With COVID-19

Commentaries: Covid-19: Ambulatory Management with Home Oxygen Results in Low Mortality, Low Readmissions – Physician’s Weekly AND Mortality, readmission low with COVID-19 discharge on home oxygen – HealthDay

 

Commentaries on Twitter

 


Cohort study: High thrombotic risk in cancer patients receiving immunotherapy

5 Apr, 2021 | 01:08h | UTC

High thrombotic risk in cancer patients receiving immunotherapy – Medical University of Vienna

Original study: Incidence, risk factors, and outcomes of venous and arterial thromboembolism in immune checkpoint inhibitor therapy – Blood

 


Exceedingly rare side effects reported with AstraZeneca vaccine in the UK – 22 cases of cerebral venous sinus thrombosis with low levels of platelets out of 18 million vaccinated individuals

5 Apr, 2021 | 01:45h | UTC

Covid-19: Seven UK blood clot deaths after AstraZeneca vaccine – BBC

Original report: Coronavirus vaccine – weekly summary of Yellow Card reporting – Medicines and Healthcare products Regulatory Agency

Related opinion: Undermining the AstraZeneca jab is a dangerous act of political folly – The Guardian

“Based on current experience, the expected benefits of both COVID-19 vaccines in preventing COVID-19 and its serious complications far outweigh any known side effects”

 


Many hospitalized Covid-19 patients are given antibiotics. That’s a problem

5 Apr, 2021 | 01:33h | UTC

Many hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT

 


Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

2 Apr, 2021 | 09:23h | UTC

Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis – The Lancet Global Health

Commentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health

 

Commentary on Twitter

 


Rapid point-of-care tests for diagnosing COVID-19 infection: the latest Cochrane evidence

2 Apr, 2021 | 09:21h | UTC

Rapid point-of-care tests for diagnosing COVID-19 infection: the latest Cochrane evidence – Evidently Cochrane

Original review and commentaries: Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection

 


Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials

1 Apr, 2021 | 04:02h | UTC

Summary and Infographic: Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ

Original guideline: Therapeutics and COVID-19: living guideline – World Health Organization

News release: WHO advises that ivermectin only be used to treat COVID-19 within clinical trials – World Health Organization

Commentary: WHO joins Europe, Merck in recommending against ivermectin for COVID-19 – Reuters

 

Commentary on Twitter

 


ERAS Guidelines for Perioperative Care for Emergency Laparotomy: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization

1 Apr, 2021 | 03:35h | UTC

Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization – World Journal of Surgery

 


Consensus Document: Management of superficial and deep surgical site infection

1 Apr, 2021 | 03:33h | UTC

Management of superficial and deep surgical site infection: an international multidisciplinary consensus – Updates in Surgery

Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery AND Global guidelines on the prevention of surgical site infection – World Health Organization AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence AND APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control

 


Troponin Testing in Patients With Supraventricular Tachycardia—Are We Overtesting? A Teachable Moment

30 Mar, 2021 | 03:07h | UTC

Troponin Testing in Patients With Supraventricular Tachycardia—Are We Overtesting? A Teachable Moment – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Updating Our Thinking on Troponin Use and Interpretation (free for a limited period)

 


Science, Medicine, and the Anesthesiologist – Key Papers from the Most Recent Literature Relevant to Anesthesiologists

30 Mar, 2021 | 02:59h | UTC

Science, Medicine, and the Anesthesiologist – Anesthesiology

 


Analysis of conflicts of interest among authors and researchers of European clinical guidelines in cardiovascular medicine

30 Mar, 2021 | 02:53h | UTC

Analysis of conflicts of interest among authors and researchers of European clinical guidelines in cardiovascular medicine – Clinical Medicine Journal

 

Commentary on Twitter (thread – click for more)

 


The management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: key points from the ESC 2020 Clinical Practice Guidelines for the general and emergency physician

30 Mar, 2021 | 02:51h | UTC

The management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: key points from the ESC 2020 Clinical Practice Guidelines for the general and emergency physician – Clinical Medicine Journal

 


COVID-19, Personal Protective Equipment, and Human Performance

30 Mar, 2021 | 03:14h | UTC

COVID-19, Personal Protective Equipment, and Human Performance – Anesthesiology

 


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