Pediatrics - Hematology-Oncology
Recent progress in the treatment of cancer in children
5 Apr, 2021 | 01:15h | UTCRecent progress in the treatment of cancer in children – CA: A Cancer Journal for Clinicians
Preliminary study finds a low-calorie diet and mild exercise may improve survival for young people with leukemia
2 Apr, 2021 | 09:12h | UTC
Rethinking Success in Pediatric Oncology: Beyond 5-Year Survival
31 Mar, 2021 | 02:56h | UTCRethinking Success in Pediatric Oncology: Beyond 5-Year Survival – Journal of Clinical Oncology
Systematic review: Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease
23 Mar, 2021 | 02:09h | UTC
Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study
5 Mar, 2021 | 08:10h | UTCGlobal patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Global thyroid cancer overdiagnosis in children and adolescents – MDEdge (free registration required) AND Global Thyroid Cancer Overdiagnosis in Children and Adolescents – Medscape (free registration required)
Commentary on Twitter
New #IARCpaper shows the incidence of thyroid cancer in children & adolescents, a rare condition everywhere before 2000, has increased rapidly in recent years in many countries, & suggests overdiagnosis is likely to be the main driver of these increases https://t.co/1ct8iEJSty pic.twitter.com/JIjBBAyKNv
— IARC (@IARCWHO) January 20, 2021
RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia
3 Mar, 2021 | 08:19h | UTCEffect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)
Bleeding in critically ill children—review of literature, knowledge gaps, and suggestions for future investigation
19 Feb, 2021 | 02:23h | UTC
Defining the optimal total number of chemotherapy courses in younger patients with Acute Myeloid Leukemia: A comparison of 3 vs. 4 courses
19 Feb, 2021 | 02:06h | UTCDefining the Optimal Total Number of Chemotherapy Courses in Younger Patients With Acute Myeloid Leukemia: A Comparison of Three Versus Four Courses – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: Optimal Number of Treatment Courses Explored in Younger Patients with AML – CancerNetwork
Commentary on Twitter
What is the optimal number of chemotherapy courses in younger patients with acute myeloid leukemia (AML)? This study evaluates 3 vs 4 courses https://t.co/peC7Xo3BbX #leusm #JCO pic.twitter.com/OGChNkYS0X
— ASCO Publications (@ASCO_pubs) January 6, 2021
RCT: Total Body Irradiation vs. Chemotherapy Conditioning in Childhood ALL
9 Feb, 2021 | 00:39h | UTCCommentary: TBI Beats Chemoconditioning for ALL Transplants in Children – Medscape (free registration required)
Commentary on Twitter
Total body irradiation or chemotherapy conditioning in childhood acute lymphoblastic leukemia (ALL) — outcomes suggest there's still a role for TBI https://t.co/ICTC0iEGN8 #leusm #pedonc #pedcsm #JCO pic.twitter.com/xARMBlSeni
— ASCO Publications (@ASCO_pubs) December 26, 2020
RCT: Posaconazole noninferior to voriconazole for primary treatment of invasive aspergillosis
7 Feb, 2021 | 21:00h | UTCPosaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Cohort study: Tomographic radiation in patients who underwent appendectomy linked to increased risk of hematologic malignant neoplasms
22 Jan, 2021 | 08:25h | UTCRisk of Hematologic Malignant Neoplasms From Abdominopelvic Computed Tomographic Radiation in Patients Who Underwent Appendectomy – JAMA Surgery (free for a limited period)
Commentary: Optimizing the Gold Standard—Low-Dose Computed Tomography Modalities as a Part of Clinical Practice in Acute Appendicitis Imaging – JAMA Surgery (free for a limited period)
Author Interview: Risk of Hematologic Malignant Neoplasms From Abdominopelvic CT Radiation