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Pediatrics – Hematology/Oncology

10-year outcomes of a RCT: Time to cure for childhood and young adult Acute Lymphoblastic Leukemia is independent of early risk factors.

20 Jun, 2022 | 00:49h | UTC

Time to Cure for Childhood and Young Adult Acute Lymphoblastic Leukemia Is Independent of Early Risk Factors: Long-Term Follow-Up of the UKALL2003 Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


RCT: Efficacy of mobile instant messaging–delivered brief motivational interviewing for parents to promote physical activity in pediatric cancer survivors.

15 Jun, 2022 | 10:53h | UTC

Efficacy of Mobile Instant Messaging–Delivered Brief Motivational Interviewing for Parents to Promote Physical Activity in Pediatric Cancer Survivors: A Randomized Clinical Trial – JAMA Network Open

Invited commentary: Improving Physical Activity in Pediatric Cancer Survivors—Engaging Parents – JAMA Network Open

 

Commentary on Twitter

 


Cross Sectional Study: Underdiagnosis and undertreatment of modifiable cardiovascular risk factors among survivors of childhood cancer.

15 Jun, 2022 | 10:43h | UTC

Underdiagnosis and Undertreatment of Modifiable Cardiovascular Risk Factors Among Survivors of Childhood Cancer – Journal of the American Heart Association

Commentaries:

Survivors of Childhood Cancer More Likely to Be Undertreated for CVD Risk Factors – AMJC

Childhood cancer survivors 80% more likely to be undertreated for cardiovascular risk factors – News Medical

 


ESTRO ACROP and SIOPE recommendations for myeloablative total body irradiation in children.

7 Jun, 2022 | 10:52h | UTC

ESTRO ACROP and SIOPE recommendations for myeloablative total body irradiation in children – Radiotherapy & Oncology

 


Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukemia, by subtype, during 2000–14: analysis of individual data from 258 cancer registries in 61 countries.

12 May, 2022 | 10:02h | UTC

Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3): analysis of individual data from 258 cancer registries in 61 countries – The Lancet Child & Adolescent Health

 


National, regional, and global estimates of anemia by severity in women and children for 2000–19.

20 Apr, 2022 | 09:25h | UTC

National, regional, and global estimates of anaemia by severity in women and children for 2000–19: a pooled analysis of population-representative data – The Lancet Global Health

Invited Commentary: Sustainable Development Goals for anaemia: 20 years later, where are we now? – The Lancet Global Health

 


Guidance on the need for contraception related to use of pharmaceuticals: providing information on the proper use of pharmaceuticals in patients with reproductive potential.

31 Mar, 2022 | 07:49h | UTC

Guidance on the need for contraception related to use of pharmaceuticals: the Japan Agency for Medical Research and Development Study Group for providing information on the proper use of pharmaceuticals in patients with reproductive potential

 


RCT: Effects of freshly irradiated vs. irradiated and stored red blood cell transfusion on cerebral oxygenation in preterm infants.

29 Mar, 2022 | 08:44h | UTC

Effects of Freshly Irradiated vs Irradiated and Stored Red Blood Cell Transfusion on Cerebral Oxygenation in Preterm Infants: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Editorial: Use of Irradiated Red Blood Cell Transfusions in Newborns to Improve Intracerebral Saturation – JAMA Pediatrics (free for a limited period)

 

Commentary on Twitter

 


Review | Imaging findings of gastrointestinal tract tumors in children and adolescents.

25 Mar, 2022 | 08:38h | UTC

Imaging findings of gastrointestinal tract tumors in children and adolescents – Insights into Imaging

 


Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents.

22 Mar, 2022 | 08:34h | UTC

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira – 2022 – Hematology, Transfusion and Cell Therapy

Related: RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

 


Podcast: Pediatric cancer survivorship.

8 Mar, 2022 | 08:26h | UTC

#44: Pediatric Cancer Survivorship – Focusing on Thriving, Not Just Surviving – The Cribsiders

 


Guideline: Management of Clostridioides difficile infection in hematopoietic cell transplant recipients.

3 Mar, 2022 | 08:17h | UTC

American Society for Transplantation and Cellular Therapy Series: #5 – Management of Clostridioides difficile infection in hematopoietic cell transplant recipients – Transplantation and Cellular Therapy

See other articles in the series:

American Society of Transplantation and Cellular Therapy Series, 1: Enterobacterales Infection Prevention and Management after Hematopoietic Cell Transplantation

 

American Society of Transplantation and Cellular Therapy Series, 2: Management and Prevention of Aspergillosis in Hematopoietic Cell Transplantation Recipients

 

American Society for Transplantation and Cellular Therapy Series: #3—Prevention of Cytomegalovirus Infection and Disease After Hematopoietic Cell Transplantation

 

American Society for Transplantation and Cellular Therapy Series: #4 – Cytomegalovirus treatment and management of resistant or refractory infections after hematopoietic cell transplantation

 


Meta-analysis showed a 2.4-fold increased risk of cancer in patients with pediatric-onset inflammatory bowel disease.

3 Mar, 2022 | 08:06h | UTC

Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease: A Meta-analysis of Population-Based Studies – JAMA Network Open

Commentary: Kids With IBD Need Close Monitoring as They Grow Up — Meta-analysis confirms: substantially increased cancer risk in adulthood – MedPage Today (free registration required)

 


Educational Review: Multiparametric MRI evaluation of bone sarcomas in children.

3 Mar, 2022 | 07:54h | UTC

Multiparametric MRI evaluation of bone sarcomas in children – Insights into Imaging

 


IPSO Pediatric Surgical Oncology Surgical Practice Guidelines.

21 Feb, 2022 | 08:44h | UTC

International Society of Paediatric Surgical Oncology (IPSO) Surgical Practice Guidelines – eCancer

 


RCT: Olanzapine may improve the control of vomiting in the delayed phase in children receiving highly emetogenic chemotherapy.

30 Jan, 2022 | 14:13h | UTC

Efficacy and Safety of Olanzapine in Children Receiving Highly Emetogenic Chemotherapy: A Randomized, Double-blind Placebo-controlled Phase 3 Trial – Journal of Pediatric Hematology/Oncology (link to abstract – $ for full-text)

 


Impact of the COVID‐19 pandemic on pediatric oncology providers globally: A mixed‐methods study.

27 Jan, 2022 | 09:46h | UTC

Impact of the COVID‐19 pandemic on pediatric oncology providers globally: A mixed‐methods study – Cancer

Editorial: The impact of the COVID‐19 pandemic in pediatric oncology units: A lesson of resilience and hope – Cancer

News Release: How has the COVID-19 pandemic impacted clinicians who care for children with cancer? – Wiley

 


M-A: Late kidney effects of nephron-sparing vs. radical nephrectomy for Wilms Tumor.

27 Jan, 2022 | 09:22h | UTC

Late Kidney Effects of Nephron-Sparing vs Radical Nephrectomy for Wilms Tumor: A Systematic Review and Meta-Analysis – The Journal of Urology (link to abstract – $ for full-text)

 


ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question in children.

25 Jan, 2022 | 09:33h | UTC

The ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question – Blood Advances

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


Expert consensus for plasma and platelet transfusion practice in critically ill children.

20 Jan, 2022 | 08:44h | UTC

Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative—Control/Avoidance of Bleeding (TAXI-CAB) – Pediatric Critical Care Medicine

 


RCT: Sirolimus plus prednisolone vs. sirolimus monotherapy for kaposiform hemangioendothelioma.

18 Jan, 2022 | 09:08h | UTC

Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial – Blood (link to abstract – $ for full-text)

 


Best Practice Recommendations: Management of adults and children receiving CAR T-cell therapy.

12 Jan, 2022 | 08:31h | UTC

Management of Adults and Children receiving CAR T-cell therapy: 2021 Best Practice Recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA) – Annals of Oncology

 


RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

11 Jan, 2022 | 02:10h | UTC

Hydroxyurea for primary stroke prevention in children with sickle cell anaemia in Nigeria (SPRING): a double-blind, multicentre, randomised, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)

 


Non-inferiority randomized trial showed radiotherapy can be safely omitted in many children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma.

10 Dec, 2021 | 10:04h | UTC

Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma (EuroNet-PHL-C1): a titration study with an open-label, embedded, multinational, non-inferiority, randomised controlled trial – The Lancet Oncology

 


Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance.

7 Dec, 2021 | 08:47h | UTC

Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance – European Journal of Cancer

 


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