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[Press release – not published yet] Moderna’s COVID-19 vaccine candidate shows 94.5% protection in an interim analysis of the phase 3 COVE study

17 Nov, 2020 | 09:55h | UTC

Press release: Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study

See also: Moderna Announces Longer Shelf Life for its COVID-19 Vaccine Candidate at Refrigerated Temperatures

Commentaries: What Moderna’s Covid-19 vaccine results mean for ending the pandemic – Vox AND Moderna follows Pfizer with exciting vaccine news – how to read these dramatic developments – The Conversation AND Moderna’s COVID Vaccine Is  95% Effective – Independent NIH-Appointed Board Assessment – Higher Storage Temperature Make It Even Better News – Health Policy Watch AND Moderna’s Vaccine News “Encouraging” But Won’t Solve Immediate Problem of Virus Surge in Europe & Americas – WHO – Health Policy Watch AND COVID vaccine excitement builds as Moderna reports third positive result – Nature AND Moderna’s Covid-19 vaccine is strongly effective, early look at data show – STAT AND With strong data on two Covid-19 vaccines, we have more answers about the road ahead — and questions too – STAT AND Early data show Moderna’s COVID vaccine 94.5% effective – CIDRAP AND A Note Of Caution On Moderna’s Promising Covid-19 Vaccine News – Forbes AND Promising Interim Results from Clinical Trial of NIH-Moderna COVID-19 Vaccine – NIH News Releases AND Moderna: Covid vaccine shows nearly 95% protection – BBC AND Latest vaccine success is good news but high price may restrict access – The Guardian AND ‘Just beautiful’—Another COVID-19 vaccine, from newcomer Moderna, succeeds in large-scale trial – Science AND Moderna trial success gives world more hope in race to end pandemic – Reuters AND Expert reaction to Moderna announcement of its phase 3 vaccine interim results – Science Media Centre

 

Worldwide measles deaths climb 50% from 2016 to 2019, claiming over 207 500 lives in 2019

17 Nov, 2020 | 09:34h | UTC

Worldwide measles deaths climb 50% from 2016 to 2019 claiming over 207 500 lives in 2019 – World Health Organization

See also: Action needed now to prevent further increases in measles and measles deaths in the coming years – The Lancet AND Progress Toward Regional Measles Elimination — Worldwide, 2000–2019 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

 

Perspective: The third surge is breaking health-care workers

16 Nov, 2020 | 01:46h | UTC

‘No One Is Listening to Us’. More people than ever are hospitalized with COVID-19. Health-care workers can’t go on like this. – The Atlantic

 

Commentary from the author (thread – click for more)

 

Long Covid: 2 months after being hospitalized for Covid-19, many patients persisted symptomatic and did not resume normal activities

13 Nov, 2020 | 09:28h | UTC

Sixty-Day Outcomes Among Patients Hospitalized With COVID-19 – Annals of Internal Medicine

Commentary: Life after COVID hospitalization: Study shows major lasting effects on health, work and more – University of Michigan

 

Commentary on Twitter

 

Long Covid: Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection

13 Nov, 2020 | 09:27h | UTC

Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection – PLOS One

Commentary: Half of recovered COVID-19 patients report lingering fatigue – CIDRAP

 

[Abstract Only] Study: An automated predictive model can identify hospitalized adults outside the ICU at risk for clinical deterioration for whom interventions by rapid-response teams could be implemented

13 Nov, 2020 | 09:16h | UTC

Automated Identification of Adults at Risk for In-Hospital Clinical Deterioration – New England Journal of Medicine (link to abstract – $ for full-text)

 

[Abstract Only] Large randomized trial fails to show benefit from a multifactorial prevention strategy to prevent falls and fractures in older people

6 Nov, 2020 | 09:48h | UTC

Screening and Intervention to Prevent Falls and Fractures in Older People – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: No reduction in fractures seen in falls prevention programmes prescribed to older people – University of Warwick

Related study: A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries – New England Journal of Medicine

 

Perspective: Reinventing pediatrics through video care first

3 Nov, 2020 | 02:57h | UTC

Reinventing Pediatrics Through Video Care First – JAMA Pediatrics (free for a limited period)

 

Cohort study: Risk of hospital admission with Covid-19 in healthcare workers and their households

2 Nov, 2020 | 02:35h | UTC

Risk of hospital admission with coronavirus disease 2019 in healthcare workers and their households: nationwide linkage cohort study – The BMJ

Commentaries: High-risk COVID contact puts health workers, patients, families at risk – CIDRAP AND Health workers and their families account for 1 in 6 hospital COVID-19 cases – BMJ

 

Commentary on Twitter

 

Randomized trial: Validation of an enhanced recovery after surgery protocol in gynecologic surgery

29 Oct, 2020 | 09:07h | UTC

Validation of an enhanced recovery after surgery protocol in gynecologic surgery: an Italian randomized study – American Journal of Obstetrics & Gynecology

Related Systematic Review: Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review – Health Services and Delivery Research AND Summary: People leave hospital after surgery sooner if hospitals follow ‘enhanced recovery protocols’ – NIHR

See also: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

Commentary on Twitter

 

CDC Report on health care personnel hospitalized with COVID-19

28 Oct, 2020 | 09:17h | UTC

COVID-19–Associated Hospitalizations Among Health Care Personnel — COVID-NET, 13 States, March 1–May 31, 2020 – Centers for Disease Control and Prevention

Commentary: Nurses Make Up Most Hospitalized Coronavirus Health Care Workers, CDC Finds – U.S. News

 

Commentary on Twitter (thread – click for more)

 

Outpatient management of COVID-19: Rapid evidence review

28 Oct, 2020 | 09:11h | UTC

Outpatient Management of COVID-19: Rapid Evidence Review – American Family Physician

 

Preventing the spread of SARS-CoV-2 with masks and other “low-tech” interventions

27 Oct, 2020 | 09:51h | UTC

Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions – JAMA

 

Commentary on Twitter

 

Narrative systematic review: Benefits of medication charts provided at transitions of care

25 Oct, 2020 | 23:29h | UTC

Benefits of medication charts provided at transitions of care: a narrative systematic review – BMJ Open

 

Study: Low risk of SARS-CoV-2 transmission among coworkers in a surgical environment

23 Oct, 2020 | 09:05h | UTC

Risk of SARS-CoV-2 Transmission Among Coworkers in a Surgical Environment – Mayo Clinic Proceedings

 

New 2020 AHA Guidelines for CPR and emergency cardiovascular care in adults and children

22 Oct, 2020 | 09:47h | UTC

2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care – Circulation

Highlights: 2020 AHA Guidelines Update for CPR and ECC

Executive Summary: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

News release: Updated CPR guidelines tackle health disparities, management of opioid-related emergencies and physical, emotional recovery – American Heart Association

 

Best practices in managing cardiac arrest in the emergency department during the COVID-19 pandemic

22 Oct, 2020 | 09:44h | UTC

Best Practices in Managing Cardiac Arrest in the Emergency Department During the COVID-19 Pandemic – Mayo Clinic Proceedings

 

Professionalism revealed: Rethinking quality improvement in the wake of a pandemic

22 Oct, 2020 | 09:32h | UTC

Professionalism Revealed: Rethinking Quality Improvement in the Wake of a Pandemic – NEJM Catalyst

 

[Preprint] Multi-organ impairment in low-risk individuals with long COVID

18 Oct, 2020 | 23:18h | UTC

Multi-organ impairment in low-risk individuals with long COVID – medRxiv

Related study (preprint): Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services – medRxiv

 

Commentary on Twitter

 

Improving prone positioning for severe ARDS during the COVID-19 pandemic: An implementation mapping approach

18 Oct, 2020 | 23:17h | UTC

Improving Prone Positioning for Severe ARDS during the COVID-19 Pandemic: An Implementation Mapping Approach – Annals of the American Thoracic Society

Commentary: Study examines ways to improve prone positioning for severe ARDS during COVID-19 pandemic – News Medical / American Thoracic Society

 

Commentary on Twitter

 

NIHR dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid)

18 Oct, 2020 | 23:14h | UTC

A dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid) – National Institute for Health Research

News Release: Living with COVID: NIHR publishes dynamic themed review into ‘ongoing COVID’

Commentaries: Coronavirus: ‘Long Covid could be four different syndromes’ – BBC AND Long covid could be four different syndromes, review suggests – The BMJ AND ‘Long COVID’ may affect multiple parts of body and mind, doctors say – Reuters

 

NEW Special issue of The Global Burden of Disease Study 2019

16 Oct, 2020 | 09:31h | UTC

Homepage: Global Burden of Disease Study 2019 – The Lancet

Editorial: Global health: time for radical change? – The Lancet

 

Commentary on Twitter

 

IDSA Position Statement: “Herd immunity” is not an answer to a pandemic

15 Oct, 2020 | 09:31h | UTC

“Herd Immunity” is Not an Answer to a Pandemic – Infectious Diseases Society of America

 

Commentary on Twitter

 

Review: The duration of infectiousness of individuals infected with SARS-CoV-2

15 Oct, 2020 | 09:26h | UTC

The duration of infectiousness of individuals infected with SARS-CoV-2 – Journal of Infection

 

Commentary on Twitter

 

Study: Polypharmacy (taking > 10 medications) is common in older patients with heart failure

15 Oct, 2020 | 09:03h | UTC

Polypharmacy in Older Adults Hospitalized for Heart Failure – Circulation: Heart Failure

Commentaries: Ten or more medications, often prescribed to older heart failure patients, raises concerns – American Heart Association AND Polypharmacy Common Among Older Heart Failure Patients – Physician’s Weekly

 

Commentary on Twitter

 

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