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Vaccines

Impact of routine childhood immunization in reducing vaccine-preventable diseases in the US.

21 Sep, 2022 | 13:11h | UTC

Impact of Routine Childhood Immunization in Reducing Vaccine-Preventable Diseases in the United States – Pediatrics

 


RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.

13 Sep, 2022 | 13:19h | UTC

Influenza vaccination strategy in acute coronary syndromes: the VIP-ACS trial – European Heart Journal

 

Commentary on Twitter

 


Study raises concerns about the effectiveness of the monkeypox vaccine.

6 Sep, 2022 | 14:39h | UTC

Study raises concerns about the effectiveness of the monkeypox vaccine – STAT

Original Study (Preprint): Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals – medRxiv

 


FDA authorizes updated COVID boosters from Moderna and Pfizer.

5 Sep, 2022 | 14:36h | UTC

FDA authorizes updated COVID boosters from Moderna and Pfizer – CIDRAP

FDA News Release: Coronavirus (COVID-19) Update: FDA Authorizes Moderna, Pfizer-BioNTech Bivalent COVID-19 Vaccines for Use as a Booster Dose – U.S. Food & Drug Administration

 


Review | Covid-19 vaccines — immunity, variants, boosters.

1 Sep, 2022 | 11:57h | UTC

Covid-19 Vaccines — Immunity, Variants, Boosters – New England Journal of Medicine

 


Long-term follow up of a RCT | Precancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine.

24 Aug, 2022 | 13:53h | UTC

Precancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine: an analysis of the long-term follow-up study from the randomised Costa Rica HPV Vaccine Trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Clinical Unmasking May Cause Increased Rates of High-Grade Cervical Neoplasia From Non–Vaccine Preventable HPV – Cancer Network

 

Commentary on Twitter

 


WHO Guidance | Behavioral and social drivers of vaccination: tools and practical guidance for achieving high uptake.

22 Aug, 2022 | 12:13h | UTC

Behavioural and social drivers of vaccination: tools and practical guidance for achieving high uptake – World Health Organization

 


UK approves updated Moderna vaccine targeting Omicron variant.

16 Aug, 2022 | 13:49h | UTC

UK approves updated Moderna vaccine targeting Omicron variant – Associated Press/MedicalXpress

See also: Covid: UK first country to approve dual-strain vaccine – BBC

 


M-A | Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course.

15 Aug, 2022 | 12:21h | UTC

Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis – The Lancet Global Health

Invited Commentary: Infant BCG vaccination is beneficial, but not sufficient – The Lancet Global Health

News Release: BCG vaccine prevents tuberculosis in young children, but not adults – Boston University School of Public Health

 

Commentary from the author on Twitter (thread – click for more)

 


RCT | Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi.

15 Aug, 2022 | 11:55h | UTC

Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial – The Lancet Global Health

Commentaries:

Typhoid conjugate vaccine: are we heading towards the elimination of typhoid in endemic countries? – The Lancet Global Health

New TCV data from Malawi highlight longer-term immune response – Coalition Against Typhoid

Related:

Safety and Efficacy of a Typhoid Conjugate Vaccine in Malawian Children – New England Journal of Medicine

Cluster RCT: Vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh conferred 85% total protection.

Randomized Trial: Efficacy Analysis of a Typhoid Conjugate Vaccine

 


Cohort Study | Incidence of acute chest syndrome in children with sickle cell disease following implementation of the 13-valent pneumococcal conjugate vaccine.

3 Aug, 2022 | 13:53h | UTC

Incidence of Acute Chest Syndrome in Children With Sickle Cell Disease Following Implementation of the 13-Valent Pneumococcal Conjugate Vaccine in France – JAMA Network Open

 

Commentary on Twitter

 


Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.

25 Jul, 2022 | 13:03h | UTC

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden – The Lancet Regional Health Europe

Related:

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities – JAMA Internal Medicine

Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study – The BMJ

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

 


Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.

25 Jul, 2022 | 12:54h | UTC

Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan – JAMA Network Open

 

Commentary on Twitter

 


Cohort Study | Effectiveness of the Pfizer vaccine against Omicron in children 5 to 11 years of age.

21 Jul, 2022 | 13:28h | UTC

Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of Age – New England Journal of Medicine

 


A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.

20 Jul, 2022 | 12:27h | UTC

A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics – American Journal of Obstetrics and Gynecology

Commentary: Study suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle length – News Medical

 


Who to vaccinate first? A peek at decision-making in a pandemic.

19 Jul, 2022 | 13:40h | UTC

Who to vaccinate first? A peek at decision-making in a pandemic – Nature

 


A pandemic treaty for equitable global access to medical countermeasures: seven recommendations for sharing intellectual property, know-how and technology.

19 Jul, 2022 | 13:38h | UTC

A pandemic treaty for equitable global access to medical countermeasures: seven recommendations for sharing intellectual property, know-how and technology – BMJ Global Health

 


WHO | COVID-19 pandemic fuels largest continued backslide in vaccinations in three decades.

18 Jul, 2022 | 11:45h | UTC

COVID-19 pandemic fuels largest continued backslide in vaccinations in three decades – World Health Organization

Commentaries:

WHO, UNICEF sound alarm over childhood immunization slide – CIDRAP

Expert reaction to data from WHO and UNICEF on global childhood vaccination rates, including against diphtheria, tetanus and pertussis (DTP3); HPV; and measles – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 


Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.

18 Jul, 2022 | 11:34h | UTC

Reactogenicity of Simultaneous COVID-19 mRNA Booster and Influenza Vaccination in the US – JAMA Network Open

Commentaries:

More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP

Reactogenicity and Concomitant Administration of the COVID-19 Booster and Influenza Vaccine – JAMA Network Open

 


Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.

18 Jul, 2022 | 11:30h | UTC

Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review – The BMJ

News Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom

 


7 of your most pressing monkeypox vaccine questions, answered – “We have safe, effective options — but in short supply”.

15 Jul, 2022 | 13:00h | UTC

7 of your most pressing monkeypox vaccine questions, answered – Vox

Related:

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


FDA authorizes emergency use of Novavax COVID-19 vaccine.

14 Jul, 2022 | 13:01h | UTC

Coronavirus (COVID-19) Update: FDA Authorizes Emergency Use of Novavax COVID-19 Vaccine, Adjuvanted – U.S. Food & Drug Administration

Commentaries:

FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT

US regulators OK new COVID-19 shot option from Novavax – Associated Press

 


Nationwide cohort study | Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines.

14 Jul, 2022 | 12:52h | UTC

Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines: nationwide cohort study – The BMJ

 


European Medicines Agency recommends second COVID booster for people over 60 – as WHO ponders guidance.

11 Jul, 2022 | 12:41h | UTC

European Medicines Agency Recommends Second COVID Booster for People Over 60 – as WHO Ponders Guidance – Health Policy Watch

 


Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.

7 Jul, 2022 | 13:00h | UTC

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

 


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