Vaccines
WHO: Vaccine inequity undermining global economic recovery.
23 Jul, 2021 | 10:53h | UTCNews release: Vaccine inequity undermining global economic recovery – World Health Organization
Dashboard: Global Dashboard for Vaccine Equity
Commentaries: Urgent need for COVID-19 vaccine equity – University of Oxford AND COVID-19 Vaccine Inequity Undermines Global Economic Recovery – Health Policy Watch
Commentary on Twitter (thread – click for more)
COVID-19 vaccine inequity is undermining 🌍 economic recovery. 🆕WHO, @UNDP and @BlavatnikSchool Dashboard on #VaccinEquity finds that low-income countries would add $38B to their GDP forecast if they had the same vaccination rate as high-income countrieshttps://t.co/BsYF2eYL1G
— World Health Organization (WHO) (@WHO) July 22, 2021
Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.
22 Jul, 2021 | 11:16h | UTCCommentaries: Study Finds Pfizer And AstraZeneca Vaccines Effective Against The Delta Variant — As Long As You Get Both Doses – Forbes AND Pfizer’s COVID-19 vaccine works very well against the Delta variant — but only after 2 doses – Insider
Related: [Preprint] 2 doses of Covid vaccines (Pfizer-BioNTech or Oxford-AstraZeneca) highly effective against hospitalization from Delta variant. AND Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization. AND Should I get my second AstraZeneca dose? Yes, it almost doubles your protection against Delta.
Commentary on Twitter
Public Health England's test-negative case-control study for Delta variant now in NEJM: over 14,000 people with Alpha, over 4,000 with Delta https://t.co/3l1QhKeXBT
Vax effectiveness against testing positive for Delta after 2 doses:
– BNT-Pfizer 88.0% (85-90)
– AZ 67.0% (61-72) pic.twitter.com/9UFy6CLSWw— Hilda Bastian, PhD (@hildabast) July 21, 2021
Should children get COVID vaccines? What the science says.
22 Jul, 2021 | 11:06h | UTCShould children get COVID vaccines? What the science says – Nature
Analysis finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis.
22 Jul, 2021 | 11:05h | UTCNews release: Study finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis – American Heart Association
Original study: Myocarditis with COVID-19 mRNA Vaccines – Circulation
Commentary: Myocarditis and COVID-19 Vaccines: New Review Tackles Knowns, Unknowns – TCTMD
Commentary on Twitter
Just published ahead of print- Myocarditis with Covid mRNA Vaccines https://t.co/mc2yrr5pDV Mechanisms, benefit of COVID-19 mRNA vaccination over low risk, management strategies – review of all myocarditis cases published to date, CDC&other reports @PeterHotez @ishannovation
— BiykemBozkurt (@BiykemB) July 20, 2021
Opinion | The benefits of a COVID vaccine far outweigh the small risk of treatable heart inflammation.
22 Jul, 2021 | 10:57h | UTC
WHO and UNICEF warn of a decline in vaccinations during COVID-19.
20 Jul, 2021 | 10:27h | UTCWHO and UNICEF warn of a decline in vaccinations during COVID-19 – World Health Organization
Related: Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020.
20 Jul, 2021 | 10:04h | UTCRelated: Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.
CDC warns Covid-19 vaccines might not protect people who are immunocompromised – “CDC is looking into ongoing research exploring the possibility that immunocompromised could benefit from an additional dose”.
18 Jul, 2021 | 23:38h | UTCCDC warns Covid-19 vaccines might not protect people who are immunocompromised – CNN
Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.
15 Jul, 2021 | 09:24h | UTCMillions of children worldwide missed routine vaccinations during the pandemic, study suggests – CNN
Invited Commentary: Disruptions to childhood immunisation due to the COVID-19 pandemic – The Lancet
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
14 Jul, 2021 | 11:20h | UTCBetween BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women – JAMA
Commentary: Pfizer COVID vaccine shows 78% efficacy in pregnancy – CIDRAP
One COVID vaccine dose yields good protection in elderly, 2 studies find.
14 Jul, 2021 | 11:15h | UTCOne COVID vaccine dose yields good protection in elderly, 2 studies find – CIDRAP
Commentary on Twitter (thread – click for more)
2 research Articles on #COVID19 vaccine effectiveness in older people:
1) Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study https://t.co/ELvMCPwSHF— The Lancet Infectious Diseases (@TheLancetInfDis) June 24, 2021
Extremely rare cases of Guillain-Barré reported with Johnson & Johnson vaccine for Covid-19.
13 Jul, 2021 | 09:48h | UTCJ&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT
See also: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR AND F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.
9 Jul, 2021 | 10:16h | UTCReduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization – Nature
Commentaries: Study highlights need for full Covid vaccination to protect against Delta variant – STAT AND How does the Delta variant dodge the immune system? Scientists find clues. – The New York Times
Commentary on Twitter (thread – click for more)
Just published @Nature
Delta variant protection by mRNA and AZ vaccines requires 2-doses, little neutralizing antibody (nAb) with 1-dose, and insufficient nAb with prior covidhttps://t.co/TOgJdMe0g6 pic.twitter.com/KWLb9rBZ44— Eric Topol (@EricTopol) July 8, 2021
Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.
8 Jul, 2021 | 09:22h | UTCEffectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine
Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. AND WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Commentary on Twitter
Chile's data on Sinovac CoronaVac in NEJM: not controlled study. Model details pic 2
– doses 28 days apart (like Serrana trial)
– symptomatic disease 65.9% (65-67)
– hospitalization 87.5% (87-88)
– intensive care 90.3% (89-91)
– Covid death 86.3% (85-88)
https://t.co/CB1U8Ar163 pic.twitter.com/4HwASRCnwQ— Hilda Bastian, PhD (@hildabast) July 7, 2021
Mounting evidence suggests Sputnik COVID vaccine is safe and effective.
8 Jul, 2021 | 09:14h | UTCMounting evidence suggests Sputnik COVID vaccine is safe and effective – Nature
Study Commentary: Decreased Antibiotic Use for Acute Otitis Media and Acute Sinusitis Following Implementation of Childhood PCV13 Immunization.
8 Jul, 2021 | 08:54h | UTC
RCOG Guidance: Coronavirus (COVID-19) Vaccination in Pregnancy.
7 Jul, 2021 | 08:53h | UTCCoronavirus (COVID-19) Vaccination in Pregnancy – Royal College of Obstetricians & Gynaecologists
See also: Resources and FAQs – Royal College of Obstetricians & Gynaecologists
Commentary on Twitter
We have published an interim update to the main coronavirus and pregnancy guidance to summarise the guidance on COVID-19 vaccination and pregnancy. Find out more: https://t.co/2YDyZFrVWJ pic.twitter.com/KnwXDvZls2
— RoyalCollegeObsGyn (@RCObsGyn) July 1, 2021
Opinion | Fractionation of COVID-19 vaccine doses could extend limited supplies and reduce mortality.
6 Jul, 2021 | 10:18h | UTC
Commentary on Twitter
For accelerating global containment, the use of lower doses of vaccines, w/ potential for =/high efficacy, should be considered, by @bencowling88 @sarahcobey @NatureMedicine https://t.co/H4YtnJEsdR
Also applies to @moderna_tx https://t.co/K0yJMirXFhhttps://t.co/8k7PGOp43s pic.twitter.com/ptCA1VtKzD— Eric Topol (@EricTopol) July 5, 2021
Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.
5 Jul, 2021 | 02:39h | UTCJoint COVAX Statement on the Equal Recognition of Vaccines – World Health Organization
Commentary on Twitter (thread – click for more)
#COVAX urges all government authorities to recognize as fully vaccinated all who have received #COVID19 vaccines approved by WHO or one of 11 approved Stringent Regulatory Authorities, when making decisions on who is able to travel or attend events.
👉https://t.co/udYVrYTdMg pic.twitter.com/DihCPUmS8F
— World Health Organization (WHO) (@WHO) July 1, 2021
Opinion | Covid is a greater risk to young people than the vaccines.
5 Jul, 2021 | 02:34h | UTCCovid Is a Greater Risk to Young People Than the Vaccines – The New York Times
Counterpoint: Weighing myocarditis cases, ACIP failed to balance the harms vs benefits of 2nd doses – by Wesley Pegden AND Vaccine-Induced Myocarditis Concerns Demand Respect, Not Absolutism – Medscape (free registration required)
Commentary on Twitter
“Realize the choice is not ‘vaccinate or do nothing.’ It’s ‘vaccinate or eventually contract the coronavirus,’ and the risks that come with it.”
My latest with @celinegounder and @EMDocinTraining@NYTOpinion @acsifferlin https://t.co/wGugCuWgSs
— Jeremy Faust MD MS (ER physician) (@jeremyfaust) July 4, 2021
Roundup on Covid vaccines | A Big Hit, A Big Miss, & Mixed Vaccine Schedules: The 18-Month Mark.
5 Jul, 2021 | 02:31h | UTCA Big Hit, A Big Miss, & Mixed Vaccine Schedules: The 18-Month Mark – Absolutely Maybe Blog
Commentary on Twitter
My latest roundup on Covid vax: a big hit, a big miss, & mixed vaccine schedules. 15 vaxes with phase 3 results coming up to the 18-month mark! More than 20 controlled community impact studies now, & lots on immunocompromise | New @PLOS https://t.co/HEsuFc4af3 #IC
— Hilda Bastian, PhD (@hildabast) July 2, 2021
Why Covid-19 outbreaks in countries using Chinese vaccines don’t necessarily mean the shots have failed.
5 Jul, 2021 | 02:30h | UTC
What are the Sinopharm and Sinovac vaccines? And how effective are they? Two experts explain.
5 Jul, 2021 | 02:28h | UTC
Germany issues world’s strongest recommendation for mixing Covid-19 vaccines.
5 Jul, 2021 | 02:27h | UTCGermany issues world’s strongest recommendation for mixing Covid-19 vaccines – CNN
[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.
2 Jul, 2021 | 11:47h | UTCMixing Covid jabs has good immune response, study finds – BBC