Vaccines
EULAR/PRES recommendations for vaccination of pediatric patients with autoimmune inflammatory rheumatic diseases.
24 Jun, 2022 | 11:17h | UTC
Cohort Study: Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA.
22 Jun, 2022 | 12:07h | UTCCommentaries:
COVID-19 mRNA vaccination and myocarditis or pericarditis – The Lancet
Myocarditis and Pericarditis After the COVID-19 mRNA Vaccination – American College of Cardiology
Related:
Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.
Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.
Myocarditis after BNT162b2 vaccination in Israeli adolescents.
[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.
Heart-inflammation risk from Pfizer COVID vaccine is very low.
Comparing the Pfizer and Moderna Covid vaccines for young children.
22 Jun, 2022 | 12:02h | UTCComparing the Pfizer and Moderna Covid vaccines for young children – STAT
Related: FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP
WHO Interim statement on decision-making considerations for the use of variant updated COVID-19 vaccines.
20 Jun, 2022 | 10:42h | UTCSee also: Interim statement on the composition of current COVID-19 vaccines – World Health Organization
Commentary on Twitter (thread – click for more)
Current #COVID19 vaccines provide high levels of protection against severe disease and death from all variants. They should continue to be used.
🆕 interim statement:https://t.co/bVzzx1HnG2 pic.twitter.com/CJlAJqFr3C
— World Health Organization (WHO) (@WHO) June 17, 2022
Test-negative, case–control study: Effects of previous infection and vaccination on symptomatic omicron infections.
17 Jun, 2022 | 11:44h | UTCRelated:
Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Two new studies show vaccination provides additional protection after Covid-19 infection.
Commentary on Twitter
A study in Qatar assessed the effectiveness of previous infection, vaccination, and both against symptomatic SARS-CoV-2 caused by omicron BA.1 and BA.2 and against severe, critical, or fatal #COVID19. https://t.co/bEVD3Y1sUn pic.twitter.com/Y38a0xxead
— NEJM (@NEJM) June 15, 2022
FDA advisers OK COVID-19 vaccines for youngest kids.
17 Jun, 2022 | 11:43h | UTCFDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP
See also: FDA advisers endorse 1st COVID-19 shots for kids under 5 – Associated Press
Comparative safety of BNT162b2 and mRNA-1273 vaccines in a nationwide cohort of US veterans.
14 Jun, 2022 | 11:08h | UTC
Commentary on Twitter
1/
TODAY: We compared the safety of #COVID19 mRNA vaccines in the largest healthcare system in the US.TAKE-HOME MESSAGE: Both Moderna and Pfizer vaccines are quite safe. If interested in vaccination, you can confidently use whichever one is available.https://t.co/fFIlXwH5Qv
— Miguel Hernán (@_MiguelHernan) June 13, 2022
Maternal vaccination: a review of current evidence and recommendations.
3 Jun, 2022 | 11:40h | UTC
Commentary on Twitter
AJOG Expert Review: Maternal vaccination: a review of current evidence and recommendations – Placental transfer of IgG antibodies from maternal to fetal circulation https://t.co/yd3DQpwSoD pic.twitter.com/obicClLhzC
— AJOG (@AJOG_thegray) April 1, 2022
Network Meta-Analysis: Effectiveness of heterologous and homologous covid-19 vaccine regimens.
1 Jun, 2022 | 12:00h | UTCNews Release: Three doses of the same or mixed covid jabs work equally well against infections – BMJ
Commentary: Three jabs best for preventing Covid infections, global analysis finds – The Guardian
Analysis/Opinion: The unintended consequences of COVID-19 vaccine policy: “why mandates, passports and restrictions may cause more harm than good”.
30 May, 2022 | 11:46h | UTC
Commentary on Twitter (thread – click for more)
📢 Our paper on COVID-19 vaccine policy has been published💉🦠
We discuss 12 unintended consequences of mandates and passports across society
& argue that pandemic vaccine policies have caused more social harm than good
Read the paper: https://t.co/TeyTki0nWI pic.twitter.com/BRJQRURbUc
— Kevin Bardosh (@KevinBardosh) May 26, 2022
Covid-19: Vaccine effectiveness wanes more rapidly for cancer patients, study finds.
27 May, 2022 | 12:04h | UTCCommentary: Covid-19: Vaccine effectiveness wanes more rapidly for cancer patients, study finds – The BMJ
Study Commentary: Long COVID risk falls only slightly after vaccination, huge study shows.
26 May, 2022 | 11:25h | UTCCommentary: Long COVID risk falls only slightly after vaccination, huge study shows – Nature
Original Study: Long COVID after breakthrough SARS-CoV-2 infection – Nature Medicine
Commentary from the author on Twitter (thread – click for more)
The latest from our team in @NatureMedicine
Does vaccination protect from #LongCovid?
Vaccines modestly reduce but do not eliminate risk of Long Covid @VAResearch @vahsrd @WUSTLmed @WUSTLnews @VREFSTL@Biostayan @BCBowe https://t.co/UEexmL8svS
A thread 🧵
— Ziyad Al-Aly, MD (@zalaly) May 25, 2022
Cohort Study: Protection and waning of natural and hybrid immunity to SARS-CoV-2.
26 May, 2022 | 11:07h | UTCProtection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Editorial: Audio Interview: Waning Immunity against Covid-19
Commentary on Twitter
Protection against SARS-CoV-2 waned over time in both vaccinated and previously infected persons; an additional vaccine dose restored protection, find investigators from Israel. https://t.co/617uBmWu8l pic.twitter.com/yiDnBbCuQ5
— NEJM (@NEJM) May 25, 2022
Test-negative, case–control study: effectiveness of homologous and heterologous Covid-19 boosters against Omicron.
26 May, 2022 | 10:59h | UTC
Effectiveness of CoronaVac in children 3 to 5 years during the SARS-CoV-2 Omicron outbreak in Chile.
25 May, 2022 | 11:42h | UTC
Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study.
25 May, 2022 | 11:34h | UTCRelated recommendations:
RCT: Safety and immunogenicity of heterologous boost immunization with an orally administered aerosolized Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults.
23 May, 2022 | 01:54h | UTC
Commentary on Twitter
Mix-and-match typically refers to different shots. Here's a randomized trial of shots and an oral vaccine that ameliorates the immune responsehttps://t.co/FFWHEwS37Y @LancetRespirMed pic.twitter.com/JZyvrxCalS
— Eric Topol (@EricTopol) May 21, 2022
WHO validates 11th vaccine for COVID-19.
20 May, 2022 | 11:16h | UTCWHO validates 11th vaccine for COVID-19 – World Health Organization
Commentary on Twitter
WHO issued an emergency use listing for CONVIDECIA, a vaccine manufactured by CanSino Biologics, China, adding to a growing portfolio of #COVID19 vaccines validated by WHO https://t.co/QdpHiasT2p pic.twitter.com/2B54FwiNDl
— World Health Organization (WHO) (@WHO) May 19, 2022
Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO.
20 May, 2022 | 11:08h | UTCOriginal Statement: Interim statement on the use of additional booster doses of Emergency Use Listed mRNA vaccines against COVID-19 – World Health Organization
Related recommendations:
RCT: Evaluation of mRNA-1273 Covid-19 vaccine in children 6 to 11 years of age.
12 May, 2022 | 10:22h | UTC
Commentary on Twitter
Two 50-μg doses of mRNA-1273 vaccine were found to be safe and effective in inducing immune responses and preventing Covid-19 in children 6 to 11 years of age. https://t.co/A5SBK4zK6E pic.twitter.com/7x4JgOwK57
— NEJM (@NEJM) May 11, 2022
Phase 2 RCT: A fourth dose of an mRNA Covid-19 vaccine increases cellular and humoral immunity against SARS-CoV-2.
11 May, 2022 | 11:14h | UTCCommentaries:
What a second booster dose of mRNA COVID-19 vaccines tells us – The Lancet Infectious Diseases
Covid: Fourth-dose jab trial shows good boost – BBC
Commentary on Twitter (thread – click for more)
The results of the @CovBoost fourth dose booster substudy are now online in @TheLancetInfDis
We demonstrated fourth doses of covid vaccines were safe and well tolerated and boost antibody levels above their peak following a third dosehttps://t.co/zGi0iNCAcL
— Alasdair Munro (@apsmunro) May 10, 2022
M-A: Interventions to improve immunization coverage among children and adolescents.
11 May, 2022 | 10:45h | UTC
Kids get limited COVID protection from world’s most popular vaccines – “First analyses of two Chinese-made vaccines in young children show that the shots do provide 60–65% effectiveness against hospitalization”.
10 May, 2022 | 11:04h | UTCKids get limited COVID protection from world’s most popular vaccines – Nature
Studies show promise for 2 new COVID vaccine platforms.
9 May, 2022 | 02:12h | UTCCommentary: Studies show promise for 2 new COVID vaccine platforms – CIDRAP
Editorial: Does the World Still Need New Covid-19 Vaccines?
Commentaries on Twitter
Efficacy of a plant-based vaccine with adjuvant was 69.5% against symptomatic #COVID19 and 78.8% against moderate-to-severe disease. https://t.co/WH54QWCBdg pic.twitter.com/BiEYpJUD7D
— NEJM (@NEJM) May 4, 2022
ZF2001 vaccine has 87% efficacy against critical or severe #COVID19 for at least 6 months after full vaccination and was safe in large cohort of adults. #IDTwitter https://t.co/wsG0AXqI4Y pic.twitter.com/45fqwVrz9a
— NEJM (@NEJM) May 4, 2022
M-A of randomized trials: association of influenza vaccination with cardiovascular risk.
3 May, 2022 | 10:58h | UTCAssociation of Influenza Vaccination With Cardiovascular Risk: A Meta-analysis – JAMA Network Open
Commentary on Twitter
In this meta-analysis, seasonal flu vaccine was associated with a 34% reduced risk of major adverse cardiovascular events in 1 year, with the biggest difference in patients with recent acute coronary syndrome. @WCHResearch @PMunkCardiacCtr https://t.co/SPrXNfMQJS
— JAMA Network Open (@JAMANetworkOpen) April 29, 2022