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Neurology

Intracerebral hemorrhage: diagnosis, emergency management, and prognosis.

15 Oct, 2021 | 02:12h | UTC

Intracerebral Hemorrhage: Diagnosis, Emergency Management, and Prognosis – emDocs

 

Autoimmune encephalitis–related seizures and epilepsy: diagnostic and therapeutic approaches.

15 Oct, 2021 | 02:08h | UTC

Autoimmune Encephalitis–Related Seizures and Epilepsy: Diagnostic and Therapeutic Approaches – Mayo Clinic Proceedings

 

Commentary on Twitter

 

M-A: Frequency of Neurologic Manifestations in COVID-19 – up to one-third of patients (89% hospitalized) experienced at least one neurological manifestation.

13 Oct, 2021 | 01:40h | UTC

Frequency of Neurologic Manifestations in COVID-19: A Systematic Review and Meta-analysis – Neurology

 

M-A: New pharmacologic agents (Ditans and Gepants) are not as good as triptans for treating migraines.

13 Oct, 2021 | 01:17h | UTC

Comparison of New Pharmacologic Agents With Triptans for Treatment of Migraine: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Migraine: Older Drugs May Be Best Bet for Lessening Pain – Physician’s Weekly

 

Commentary on Twitter

 

RCT: In patients with acute ischemic stroke and large vessel occlusion, thrombectomy with combined contact aspiration and stent retriever was not better than stent retriever alone.

12 Oct, 2021 | 00:04h | UTC

Effect of Thrombectomy With Combined Contact Aspiration and Stent Retriever vs Stent Retriever Alone on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion: The ASTER2 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries:

Little Benefit From Adding Aspiration to Thrombectomy for Stroke – Medscape (free registration required)

Combo Thrombectomy Approach No Better for Large Vessel Strokes – MedPage Today (free registration required)

 

Commentary on Twitter

 

RCT: Early treatment with mild aerobic exercise safely speeds recovery from sport-related concussion in adolescents.

11 Oct, 2021 | 23:58h | UTC

Early targeted heart rate aerobic exercise versus placebo stretching for sport-related concussion in adolescents: a randomised controlled trial – The Lancet Child & Adolescent Health

News release: Aerobic exercise after a sport-related concussion speeds recovery in adolescent athletes – University at Buffalo

Related:

Randomized Trial: Early Aerobic Exercise for Sport-Related Concussion

RCT: Limiting screen time for young adults after concussion results in shorter duration of symptoms.

Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

 

Commentaries on Twitter

 

Editorial: Brain health and its social determinants.

10 Oct, 2021 | 21:35h | UTC

Brain health and its social determinants – The Lancet

 

Commentary on Twitter

 

Study shows an increased risk of Guillain-Barré Syndrome with the J&J vaccine; the estimated observed to expected rate ratio was 4.18 for the 42-day window.

8 Oct, 2021 | 10:40h | UTC

Association of Receipt of the Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barré Syndrome, February-July 2021 – JAMA

 

Commentary on Twitter

 

Choosing Wisely: Seven things physicians and residents/patients should question in long term care.

7 Oct, 2021 | 10:31h | UTC

Seven Things Physicians and Residents/Patients Should Question – Canadian Society for Long Term Care Medicine

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

AAN Position Statement: Ethical perspectives on costly drugs and health care.

5 Oct, 2021 | 08:57h | UTC

Ethical Perspectives on Costly Drugs and Health Care: AAN Position Statement – Neurology

News release: AAN Issues Ethics Position Statement on Costly Drugs and Health Care – American Academy of Neurology

 

Neurological Effects of COVID-19 in Children.

1 Oct, 2021 | 10:40h | UTC

Neurological Effects of COVID-19 in Children – Pediatric Clinics of North America

 

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

1 Oct, 2021 | 10:07h | UTC

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness – The Conversation

Related studies:

Cannabinol and Sleep: Separating Fact from Fiction – Cannabis and Cannabinoid Research

Medical Cannabis and Cannabinoids for Impaired Sleep: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – Sleep (link to abstract – $ for full-text)

 

Review: Clinical features, laboratory, and radiological findings of patients with acute inflammatory myelopathy after COVID-19 infection.

30 Sep, 2021 | 10:27h | UTC

Clinical Features, Laboratory, and Radiological Findings of Patients With Acute Inflammatory Myelopathy After COVID-19 Infection: A Narrative Review – American Journal of Physical Medicine & Rehabilitation

 

RCT: Maintenance vs. discontinuation of antidepressants in patients who felt well enough to discontinue antidepressant therapy.

30 Sep, 2021 | 10:22h | UTC

Maintenance or Discontinuation of Antidepressants in Primary Care – New England Journal of Medicine

Commentaries:

Many can stop anti-depressants without relapse – BBC

Study highlights difficulty of stopping antidepressants – Associated Press

 

AAN Position Statement: Use of social media in health care—opportunities, challenges, and ethical considerations.

30 Sep, 2021 | 10:19h | UTC

Use of Social Media in Health Care—Opportunities, Challenges, and Ethical Considerations: A Position Statement of the American Academy of Neurology – Neurology

 

RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.

28 Sep, 2021 | 09:06h | UTC

Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)

Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)

 

Commentary on Twitter

 

The AUA/SUFU Guideline on Adult Neurogenic Lower Urinary Tract Dysfunction.

26 Sep, 2021 | 21:58h | UTC

The AUA/SUFU Guideline on Adult Neurogenic Lower Urinary Tract Dysfunction – The Journal of Urology

Part I: Diagnosis and Evaluation – The Journal of Urology

Part II: Treatment and Follow up – The Journal of Urology

 

Phenotypes and subphenotypes of delirium: a review of current categorizations and suggestions for progression.

23 Sep, 2021 | 09:54h | UTC

Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression – Critical Care

 

RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.

21 Sep, 2021 | 09:01h | UTC

Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)

Commentaries:

Intervening Before 18 Months May Reduce Odds of Autism Diagnosis in Babies Identified at High Risk – Psychiatric News Alert

Expert reaction to trial looking at the effect of a pre-emptive intervention in children showing early signs of autism on developmental outcomes – Science Media Centre

Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian

 

Commentary on Twitter

 

Editorial: Brain health and its social determinants.

19 Sep, 2021 | 23:28h | UTC

Brain health and its social determinants – The Lancet

 

Commentary on Twitter

 

AAN Position Statement: Ethical Considerations in Dementia Diagnosis and Care.

17 Sep, 2021 | 10:04h | UTC

Ethical Considerations in Dementia Diagnosis and Care: AAN Position Statement – Neurology

 

Systematic Review: Interventional treatments for acute and chronic pain.

17 Sep, 2021 | 10:01h | UTC

Interventional Treatments for Acute and Chronic Pain: Systematic Review – Agency for Healthcare Research and Quality

Full report

Evidence summary

 

Case series: Vaccine-induced thrombocytopenia with severe headache may precede cerebral venous sinus thrombosis by several days – patients with severe headache 5 to 20 days after adenovirus vector vaccination against Covid-19 should undergo immediate testing for thrombocytopenia and d-dimer levels and, if available, testing for anti–PF4–heparin IgG antibodies.

16 Sep, 2021 | 10:14h | UTC

Vaccine-Induced Thrombocytopenia with Severe Headache – New England Journal of Medicine

 

Commentary on Twitter

 

Study suggests mobile stroke units (ambulances with staff and a CT scanner that may enable faster thrombolysis) may improve outcomes for ischemic stroke patients.

12 Sep, 2021 | 21:41h | UTC

Prospective, Multicenter, Controlled Trial of Mobile Stroke Units – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Patients treated by mobile stroke units had better outcomes, according to study published in NEJM – University of Texas Health Science Center at Houston

 

Commentary on Twitter (video – click to view)

 

People with Parkinson’s may benefit from seven walking strategies.

12 Sep, 2021 | 21:40h | UTC

News release: People with Parkinson’s may benefit from seven walking strategies – American Academy of Neurology

Original study: Perception and Use of Compensation Strategies for Gait Impairment by Persons With Parkinson Disease – Neurology

Commentary: Compensation Strategies Benefit Parkinson Patients With Gait Impairment – HealthDay

 

Commentary on Twitter (thread – click for more)

 

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