RCT | Recombinant human prourokinase demonstrates noninferiority to alteplase in acute ischemic stroke treatment 3 Aug, 2023 | 13:46h | UTC Efficacy and Safety of Recombinant Human Prourokinase in the Treatment of Acute Ischemic Stroke Within 4.5 Hours of Stroke Onset: A Phase 3 Randomized Clinical Trial – JAMA Network Open See also: Visual Abstract