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Radiation Oncology

Radiation therapy for rectal cancer: Executive summary of an ASTRO clinical practice guideline

28 Oct, 2020 | 08:45h | UTC

Radiation Therapy for Rectal Cancer: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology

Commentaries: ASTRO issues clinical guideline on radiation therapy for rectal cancer AND ASTRO Issues Guideline on Radiation Therapy for Rectal Cancer – Physician’s Weekly

 

Commentary on Twitter

 


[Abstract Only] Meta-analysis: Adjuvant vs. early salvage radiotherapy for the treatment of localized and locally advanced prostate cancer

29 Sep, 2020 | 10:04h | UTC

Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data – The Lancet

Commentaries: For Radiotherapy After Radical Prostatectomy, Salvage Therapy Should Be “Standard of Care” – NEJM Journal Watch AND Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back – The Daily Mail

 


Randomized trials: Salvage radiotherapy vs. adjuvant radiotherapy after radical prostatectomy

29 Sep, 2020 | 10:03h | UTC

Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial – The Lancet

Related articles: Adjuvant radiotherapy versus early salvage radiotherapy plus short-term androgen deprivation therapy in men with localised prostate cancer after radical prostatectomy (GETUG-AFU 17): a randomised, phase 3 trial – The Lancet Oncology (free registration required) AND Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial – The Lancet Oncology (free registration required)

Commentaries: For Radiotherapy After Radical Prostatectomy, Salvage Therapy Should Be “Standard of Care” – NEJM Journal Watch AND Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back – The Daily Mail

 


Advanced Prostate Cancer: AUA/ASTRO/SUO Guidelines

24 Sep, 2020 | 09:15h | UTC

Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I – The Journal of Urology

Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II – The Journal of Urology

 


[ESMO2020 press release – Not published yet] Randomized trial: No benefit for post-operative radiotherapy in non-small-cell lung cancer

22 Sep, 2020 | 09:23h | UTC

No benefit for post-operative radiotherapy in non-small-cell lung cancer – European Society of Medical Oncology

Commentary: Phase 3 Trial Results Do Not Support PORT in Resected Stage IIIAN2 NSCLC – Targeted Oncology

 


[Abstract Only] Randomized trial: Preoperative radiotherapy plus surgery vs. surgery alone for patients with primary retroperitoneal sarcoma

16 Sep, 2020 | 08:46h | UTC

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Randomized trial: Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy for early breast cancer

21 Aug, 2020 | 02:27h | UTC

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial – The BMJ

Commentaries: Targeted intraoperative radiotherapy for early breast cancer—new evidence challenges traditional treatment – The BMJ Opinion AND Long-term TARGIT-A data support single-dose intraoperative breast cancer radiotherapy – medwire News

 


[Abstract Only] Randomized trial: Hypofractionated vs. conventional fractionated radiotherapy after breast-conserving surgery

18 Aug, 2020 | 07:15h | UTC

Hypofractionated Versus Conventional Fractionated Radiotherapy After Breast-Conserving Surgery in the Modern Treatment Era: A Multicenter, Randomized Controlled Trial From China – Journal of Clinical Oncology

 


Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

13 Aug, 2020 | 00:02h | UTC

Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT – Health Technology Assessment

 


ASTRO Guideline: Radiation Therapy for Cervical Cancer

11 Jun, 2020 | 09:20h | UTC

Radiation Therapy for Cervical Cancer: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology

Commentary: ASTRO’s new guideline provides recommendations for radiation therapy to treat cervical cancer – News Medical

 


Randomized Trial: Hypofractionated Breast Radiotherapy for 1 Week Noninferior to 3 weeks

30 Apr, 2020 | 04:02h | UTC

Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial – The Lancet

Commentaries: 1-week hypofractionated adjuvant whole-breast radiotherapy: towards a new standard? – The Lancet AND One-week course of radiotherapy could benefit women with early stage breast cancer, study finds – Institute of Cancer Research

 


[Abstract Only] Randomized Trial: Hippocampal Avoidance During Whole-Brain Radiotherapy for Patients with Brain Metastases

10 Mar, 2020 | 10:17h | UTC

Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001 – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentaries: Hippocampal avoidance during WBRT reduces risks on NRG Oncology trial – NRG Oncology (free) AND ‘Practice-Changing’ Study on WBRT for Patients With Brain Mets – Medscape (free registration required)

 


ASTRO Guideline: Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin

21 Jan, 2020 | 01:35h | UTC

Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin: Executive Summary of an American Society for Radiation Oncology Clinical Practice Guideline – Practical Radiation Oncology (free)

Commentary: ASTRO Issues Clinical Guideline on Radiation Therapy for Basal Cell and Cutaneous Squamous Cell Carcinomas – The ASCO Post (free)

 


Observational Study: Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation for Localized Prostate Cancer

16 Jan, 2020 | 08:53h | UTC

Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer – JAMA (free for a limited period)

Related Study: Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received (free)

Commentaries: Prostatectomy-associated urinary incontinence disparities persist at 5 years – MedwireNews (free) AND Prostate Cancer Treatment Side Effects Worse With Prostatectomy – Renals & Urology News (free)

 


[Abstract Only] Randomized Trial: External Beam Accelerated Partial Breast Irradiation vs. Whole Breast Irradiation after Breast Conserving Surgery in Women with Ductal Carcinoma in Situ and Node-negative Breast Cancer

5 Jan, 2020 | 13:08h | UTC

External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Results mixed for twice-daily APBI in early breast cancer – MedicalXpress (free)

 

Related Commentary on Twitter

 


[Abstract Only] Randomized Trial: Accelerated Partial Breast Irradiation vs. Whole-breast Irradiation After Breast-conserving Surgery for Early-stage Breast Cancer

5 Jan, 2020 | 13:05h | UTC

Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial – The Lancet (link to abstract – $ for full-text)

 

Related Commentary on Twitter


Randomized Trial: Single-Fraction vs. Multifraction Radiotherapy for Spinal Canal Compression from Metastatic Cancer

4 Dec, 2019 | 08:18h | UTC

Effect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: One dose of radiotherapy as effective as five doses for cancer in the spine – University College London (free)

 


Randomized Trial: Synchronous vs. Sequential Chemo-radiotherapy in Patients with Early Stage Breast Cancer

4 Dec, 2019 | 08:17h | UTC

Synchronous versus sequential chemo-radiotherapy in patients with early stage breast cancer (SECRAB): A randomised, phase III, trial – Radiation & Oncology (free)

 


Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received

29 Nov, 2019 | 08:24h | UTC

Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received – European Urology (free)

Original Study: 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer – New England Journal of Medicine (free)

 

Related Commentary on Twitter

 


Meta-Analysis: Early vs. Delayed Surgery After Short-course Radiotherapy for Rectal Cancer

24 Nov, 2019 | 20:41h | UTC

Early versus delayed surgery after short-course radiotherapy for rectal cancer: A network meta-analysis of randomized Controlled Trials – Asian Journal of Surgery (free)

 


Deep Learning: A Review for the Radiation Oncologist

29 Oct, 2019 | 02:16h | UTC

Deep Learning: A Review for the Radiation Oncologist – Frontiers in Oncology (free)

 


Perspective: Alternative Payment for Radiation Oncology

10 Oct, 2019 | 09:15h | UTC

Alternative Payment for Radiation Oncology – JAMA (free for a limited period)

 


#ESMO19 – [Not Published Yet] Randomized Trial: Many Men with Prostate Cancer May Avoid Postoperative Radiotherapy, Study Suggests

30 Sep, 2019 | 00:39h | UTC

Men with Prostate Cancer can be Spared Radiotherapy after Surgery [ESMO 2019 Press Release] (free)

See also: ESMO 2019: Men With Prostate Cancer May Avoid Postoperative Radiotherapy, Study Finds – The ASCO Post (free) AND Skipping Radiotherapy After Surgery for Prostate Cancer – Medscape (free registration required)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

 


ASTRO Guideline: Radiation Therapy for Pancreatic Cancer

12 Sep, 2019 | 08:01h | UTC

Radiation Therapy for Pancreatic Cancer: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology (free)

Commentaries: ASTRO Guideline on Use of Radiation Therapy for Patients With Pancreatic Cancer – The ASCO Post (free) AND New guideline clarifies role of radiation therapy in pancreatic cancer treatment – American Society for Radiation Oncology (free)

 


[Abstract Only] Randomized Trial: Adjuvant Radiotherapy Following Radical Prostatectomy vs. Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension

10 Sep, 2019 | 00:56h | UTC

Randomised Trial of Adjuvant Radiotherapy Following Radical Prostatectomy Versus Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension – European Urology (link to abstract – $ for full-text)

Commentaries: Adjuvant Radiotherapy After Radical Prostatectomy vs Radical Prostatectomy Alone in Patients With Positive Margins or Extracapsular Extension – The ASCO Post (free) AND Adjuvant radiotherapy may be beneficial in treating locally advanced prostate cancer – University of Helsinki (free)

Source: EvidenceAlerts

 


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