Radiation Oncology
Radiation therapy for rectal cancer: Executive summary of an ASTRO clinical practice guideline
28 Oct, 2020 | 08:45h | UTCCommentaries: ASTRO issues clinical guideline on radiation therapy for rectal cancer AND ASTRO Issues Guideline on Radiation Therapy for Rectal Cancer – Physician’s Weekly
Commentary on Twitter
ASTRO issues clinical guideline on #RadiationTherapy for #RectalCancer. Recommendations address #patient selection and treatment techniques for locally advanced disease. This new guideline is published in the #PracticalRO Journal: https://t.co/Q6BDPAOxRI #RadOnc pic.twitter.com/9Zzj5BWA2o
— ASTRO (@ASTRO_org) October 21, 2020
[Abstract Only] Meta-analysis: Adjuvant vs. early salvage radiotherapy for the treatment of localized and locally advanced prostate cancer
29 Sep, 2020 | 10:04h | UTCCommentaries: For Radiotherapy After Radical Prostatectomy, Salvage Therapy Should Be “Standard of Care” – NEJM Journal Watch AND Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back – The Daily Mail
Randomized trials: Salvage radiotherapy vs. adjuvant radiotherapy after radical prostatectomy
29 Sep, 2020 | 10:03h | UTCRelated articles: Adjuvant radiotherapy versus early salvage radiotherapy plus short-term androgen deprivation therapy in men with localised prostate cancer after radical prostatectomy (GETUG-AFU 17): a randomised, phase 3 trial – The Lancet Oncology (free registration required) AND Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial – The Lancet Oncology (free registration required)
Commentaries: For Radiotherapy After Radical Prostatectomy, Salvage Therapy Should Be “Standard of Care” – NEJM Journal Watch AND Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back – The Daily Mail
Advanced Prostate Cancer: AUA/ASTRO/SUO Guidelines
24 Sep, 2020 | 09:15h | UTCAdvanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I – The Journal of Urology
Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II – The Journal of Urology
[ESMO2020 press release – Not published yet] Randomized trial: No benefit for post-operative radiotherapy in non-small-cell lung cancer
22 Sep, 2020 | 09:23h | UTCCommentary: Phase 3 Trial Results Do Not Support PORT in Resected Stage IIIAN2 NSCLC – Targeted Oncology
[Abstract Only] Randomized trial: Preoperative radiotherapy plus surgery vs. surgery alone for patients with primary retroperitoneal sarcoma
16 Sep, 2020 | 08:46h | UTCPreoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Randomized trial: Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy for early breast cancer
21 Aug, 2020 | 02:27h | UTCCommentaries: Targeted intraoperative radiotherapy for early breast cancer—new evidence challenges traditional treatment – The BMJ Opinion AND Long-term TARGIT-A data support single-dose intraoperative breast cancer radiotherapy – medwire News
[Abstract Only] Randomized trial: Hypofractionated vs. conventional fractionated radiotherapy after breast-conserving surgery
18 Aug, 2020 | 07:15h | UTC
Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT
13 Aug, 2020 | 00:02h | UTC
ASTRO Guideline: Radiation Therapy for Cervical Cancer
11 Jun, 2020 | 09:20h | UTCCommentary: ASTRO’s new guideline provides recommendations for radiation therapy to treat cervical cancer – News Medical
Randomized Trial: Hypofractionated Breast Radiotherapy for 1 Week Noninferior to 3 weeks
30 Apr, 2020 | 04:02h | UTCCommentaries: 1-week hypofractionated adjuvant whole-breast radiotherapy: towards a new standard? – The Lancet AND One-week course of radiotherapy could benefit women with early stage breast cancer, study finds – Institute of Cancer Research
[Abstract Only] Randomized Trial: Hippocampal Avoidance During Whole-Brain Radiotherapy for Patients with Brain Metastases
10 Mar, 2020 | 10:17h | UTCHippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001 – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries: Hippocampal avoidance during WBRT reduces risks on NRG Oncology trial – NRG Oncology (free) AND ‘Practice-Changing’ Study on WBRT for Patients With Brain Mets – Medscape (free registration required)
ASTRO Guideline: Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin
21 Jan, 2020 | 01:35h | UTCCommentary: ASTRO Issues Clinical Guideline on Radiation Therapy for Basal Cell and Cutaneous Squamous Cell Carcinomas – The ASCO Post (free)
Observational Study: Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation for Localized Prostate Cancer
16 Jan, 2020 | 08:53h | UTCPatient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer – JAMA (free for a limited period)
Related Study: Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received (free)
Commentaries: Prostatectomy-associated urinary incontinence disparities persist at 5 years – MedwireNews (free) AND Prostate Cancer Treatment Side Effects Worse With Prostatectomy – Renals & Urology News (free)
[Abstract Only] Randomized Trial: External Beam Accelerated Partial Breast Irradiation vs. Whole Breast Irradiation after Breast Conserving Surgery in Women with Ductal Carcinoma in Situ and Node-negative Breast Cancer
5 Jan, 2020 | 13:08h | UTCExternal beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary: Results mixed for twice-daily APBI in early breast cancer – MedicalXpress (free)
Related Commentary on Twitter
NEW: External beam accelerated partial breast irradiation was non-inferior to whole breast irradiation in preventing ipsilateral breast tumour recurrence: finding from the RAPID randomised controlled trial https://t.co/4aexxXC8Vg pic.twitter.com/JMa0jUWY1X
— The Lancet (@TheLancet) December 6, 2019
[Abstract Only] Randomized Trial: Accelerated Partial Breast Irradiation vs. Whole-breast Irradiation After Breast-conserving Surgery for Early-stage Breast Cancer
5 Jan, 2020 | 13:05h | UTCLong-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
PRESS RELEASE: Accelerated Partial Breast Irradiation Although Close was Not Equivalent to Whole-breast Irradiation to Control Ipsilateral Breast Tumor Recurrence https://t.co/mCvuC5aeag #breastcancer pic.twitter.com/KRXAAtAjbj
— NRG Oncology (@NRGonc) December 6, 2019
Randomized Trial: Single-Fraction vs. Multifraction Radiotherapy for Spinal Canal Compression from Metastatic Cancer
4 Dec, 2019 | 08:18h | UTCEffect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: One dose of radiotherapy as effective as five doses for cancer in the spine – University College London (free)
Randomized Trial: Synchronous vs. Sequential Chemo-radiotherapy in Patients with Early Stage Breast Cancer
4 Dec, 2019 | 08:17h | UTC
Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received
29 Nov, 2019 | 08:24h | UTCOriginal Study: 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer – New England Journal of Medicine (free)
Related Commentary on Twitter
Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received@Freddie_Hamdy @JimCatto https://t.co/sNfevwU3R4 pic.twitter.com/uqnoZUgSRm
— European Urology (@EUplatinum) November 25, 2019
Meta-Analysis: Early vs. Delayed Surgery After Short-course Radiotherapy for Rectal Cancer
24 Nov, 2019 | 20:41h | UTC
Deep Learning: A Review for the Radiation Oncologist
29 Oct, 2019 | 02:16h | UTCDeep Learning: A Review for the Radiation Oncologist – Frontiers in Oncology (free)
Perspective: Alternative Payment for Radiation Oncology
10 Oct, 2019 | 09:15h | UTCAlternative Payment for Radiation Oncology – JAMA (free for a limited period)
#ESMO19 – [Not Published Yet] Randomized Trial: Many Men with Prostate Cancer May Avoid Postoperative Radiotherapy, Study Suggests
30 Sep, 2019 | 00:39h | UTCMen with Prostate Cancer can be Spared Radiotherapy after Surgery [ESMO 2019 Press Release] (free)
See also: ESMO 2019: Men With Prostate Cancer May Avoid Postoperative Radiotherapy, Study Finds – The ASCO Post (free) AND Skipping Radiotherapy After Surgery for Prostate Cancer – Medscape (free registration required)
#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona
ASTRO Guideline: Radiation Therapy for Pancreatic Cancer
12 Sep, 2019 | 08:01h | UTCCommentaries: ASTRO Guideline on Use of Radiation Therapy for Patients With Pancreatic Cancer – The ASCO Post (free) AND New guideline clarifies role of radiation therapy in pancreatic cancer treatment – American Society for Radiation Oncology (free)
[Abstract Only] Randomized Trial: Adjuvant Radiotherapy Following Radical Prostatectomy vs. Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension
10 Sep, 2019 | 00:56h | UTCRandomised Trial of Adjuvant Radiotherapy Following Radical Prostatectomy Versus Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension – European Urology (link to abstract – $ for full-text)
Commentaries: Adjuvant Radiotherapy After Radical Prostatectomy vs Radical Prostatectomy Alone in Patients With Positive Margins or Extracapsular Extension – The ASCO Post (free) AND Adjuvant radiotherapy may be beneficial in treating locally advanced prostate cancer – University of Helsinki (free)
Source: EvidenceAlerts