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Radiation Oncology

Radiation therapy-associated toxicity: Etiology, management, and prevention.

15 Jul, 2021 | 09:13h | UTC

Radiation therapy-associated toxicity: Etiology, management, and prevention – CA: A Cancer Journal for Clinicians

 


Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

1 Jul, 2021 | 09:44h | UTC

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 

Commentary on Twitter

 


Randomized trial long-term results confirm the benefits of neoadjuvant chemoradiotherapy plus surgery for esophageal cancer

20 May, 2021 | 08:16h | UTC

Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial – Journal of Clinical Oncology

 

Commentaries on Twitter

 


RCT: Inclusion of 18F-fluciclovine-PET/CT imaging to guide postprostatectomy salvage radiotherapy in patients with prostate cancer may improve survival free from biochemical recurrence or persistence.

10 May, 2021 | 00:46h | UTC

18F-fluciclovine-PET/CT imaging versus conventional imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial – The Lancet (link to abstract – $ for full-text)

 


Population-based cohort study suggests increased survival after breast conservation surgery + radiotherapy compared to mastectomy with or without radiotherapy in women with breast cancer.

10 May, 2021 | 00:42h | UTC

Survival After Breast Conservation vs Mastectomy Adjusted for Comorbidity and Socioeconomic Status: A Swedish National 6-Year Follow-up of 48 986 Women – JAMA Surgery

Commentary: Breast-Conserving Surgery+RT Yields Significant Survival Benefits For Early-Stage Breast Cancer – Physician’s Weekly

 

Commentary on Twitter

 


Review: Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer

30 Apr, 2021 | 08:31h | UTC

Evolution and Current Status of the Multidisciplinary Management of Locally Advanced Rectal Cancer – JCO Oncology Practice

 


M-A: Chemotherapy and radiotherapy in locally advanced head and neck cancer

15 Apr, 2021 | 06:29h | UTC

Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis – The Lancet Oncology

 

Commentary on Twitter

 


RCT: No benefit from palliative radiotherapy after esophageal cancer stenting

18 Mar, 2021 | 08:52h | UTC

Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial – The Lancet Gastroenterology & Hepatology

 


Cohort study: Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

14 Mar, 2021 | 20:09h | UTC

Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer – JAMA Oncology (free for a limited period)

 

Commentary on Twitter

 


New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer

7 Mar, 2021 | 19:28h | UTC

News Release: New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer – World Health Organization

Technical Document: Technical specifications of radiotherapy equipment for cancer treatment

 

 


M-A: Local salvage therapies after radiotherapy for prostate cancer

3 Mar, 2021 | 08:06h | UTC

A Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER) – European Urology (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 


RCT: Endoscopic surgery improves survival compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma

28 Feb, 2021 | 20:45h | UTC

Endoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial – The Lancet Oncology

Commentary: Endoscopic Nasopharyngectomy vs IMRT for Previously Treated, Resectable, Locally Recurrent Nasopharyngeal Carcinoma – The ASCO Post

 


Guidelines in the management of CNS tumors

23 Feb, 2021 | 01:09h | UTC

Guidelines in the management of CNS tumors – Journal of Neuro-Oncology

 


Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer: ASCO guideline update

21 Feb, 2021 | 21:47h | UTC

Initial Management of Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer: ASCO Guideline Update – Journal of Clinical Oncology

 


RCT: Radiopharmaceutical therapy vs. cabazitaxel in patients with metastatic castration-resistant prostate cancer

15 Feb, 2021 | 00:29h | UTC

[177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Radionuclide Tx Wins in Third-Line Metastatic CRPC – MedPage Today

 


RCT: Total Body Irradiation vs. Chemotherapy Conditioning in Childhood ALL

9 Feb, 2021 | 00:39h | UTC

Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study – Journal of Clinical Oncology

Commentary: TBI Beats Chemoconditioning for ALL Transplants in Children – Medscape (free registration required)

 

Commentary on Twitter

 


Radiation therapy for small-cell lung cancer: ASCO Guideline endorsement of an ASTRO Guideline

29 Jan, 2021 | 01:27h | UTC

Radiation Therapy for Small-Cell Lung Cancer: ASCO Guideline Endorsement of an ASTRO Guideline – Journal of Clinical Oncology

 


ASCO Guideline Update: Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer

28 Jan, 2021 | 01:17h | UTC

Initial Management of Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer: ASCO Guideline Update – Journal of Clinical Oncology

 


Randomized trial: Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer

28 Jan, 2021 | 01:09h | UTC

Prostate-Only Versus Whole-Pelvic Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer (POP-RT): Outcomes From Phase III Randomized Controlled Trial – Journal of Clinical Oncology

 

Commentary on Twitter

 


Randomized trial: Ultra-hypofractionated vs. conventionally fractionated radiotherapy for prostate cancer

19 Jan, 2021 | 01:14h | UTC

Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer (HYPO-RT-PC): patient-reported quality-of-life outcomes of a randomised, controlled, non-inferiority, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


CSCO and ASCO Guideline: Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma

15 Jan, 2021 | 08:14h | UTC

Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline – Journal of Clinical Oncology

 


Randomized trial: Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) improve outcomes vs. traditional approach in locally advanced rectal cancer

12 Jan, 2021 | 01:12h | UTC

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Meta-analysis: Total neoadjuvant therapy vs. standard therapy in locally advanced rectal cancer

12 Jan, 2021 | 01:10h | UTC

Total Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries: Personalizing Treatment for Rectal Cancer: Total Neoadjuvant Therapy Is Leading the Way AND Total Neoadjuvant Therapy Improves Rectal Cancer Pathologic Response – Physician’s Weekly

Related meta-analysis (just published): Impact of Total Neoadjuvant Therapy vs. Standard Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review and Meta-Analysis of Randomized Trials – Cancers

 

Commentary on Twitter

 


Randomized trial: Among patients with advanced rectal cancer, short-course radiotherapy followed by chemotherapy before total mesorectal excision reduces disease-related treatment failure compared to standard treatment

15 Dec, 2020 | 01:29h | UTC

Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial – The Lancet Oncology

 

Commentary on Twitter

 


Short review: How to diagnose and manage radiation therapy cardiotoxicity

6 Dec, 2020 | 23:27h | UTC

How to Diagnose and Manage Radiation Cardiotoxicity – JACC: CardioOncology

 


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