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Radiation Oncology

[ESMO2020 press release – Not published yet] Randomized trial: No benefit for post-operative radiotherapy in non-small-cell lung cancer

22 Sep, 2020 | 09:23h | UTC

No benefit for post-operative radiotherapy in non-small-cell lung cancer – European Society of Medical Oncology

Commentary: Phase 3 Trial Results Do Not Support PORT in Resected Stage IIIAN2 NSCLC – Targeted Oncology

 


[Abstract Only] Randomized trial: Preoperative radiotherapy plus surgery vs. surgery alone for patients with primary retroperitoneal sarcoma

16 Sep, 2020 | 08:46h | UTC

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Randomized trial: Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy for early breast cancer

21 Aug, 2020 | 02:27h | UTC

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial – The BMJ

Commentaries: Targeted intraoperative radiotherapy for early breast cancer—new evidence challenges traditional treatment – The BMJ Opinion AND Long-term TARGIT-A data support single-dose intraoperative breast cancer radiotherapy – medwire News

 


[Abstract Only] Randomized trial: Hypofractionated vs. conventional fractionated radiotherapy after breast-conserving surgery

18 Aug, 2020 | 07:15h | UTC

Hypofractionated Versus Conventional Fractionated Radiotherapy After Breast-Conserving Surgery in the Modern Treatment Era: A Multicenter, Randomized Controlled Trial From China – Journal of Clinical Oncology

 


Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

13 Aug, 2020 | 00:02h | UTC

Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT – Health Technology Assessment

 


ASTRO Guideline: Radiation Therapy for Cervical Cancer

11 Jun, 2020 | 09:20h | UTC

Radiation Therapy for Cervical Cancer: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology

Commentary: ASTRO’s new guideline provides recommendations for radiation therapy to treat cervical cancer – News Medical

 


Randomized Trial: Hypofractionated Breast Radiotherapy for 1 Week Noninferior to 3 weeks

30 Apr, 2020 | 04:02h | UTC

Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial – The Lancet

Commentaries: 1-week hypofractionated adjuvant whole-breast radiotherapy: towards a new standard? – The Lancet AND One-week course of radiotherapy could benefit women with early stage breast cancer, study finds – Institute of Cancer Research

 


[Abstract Only] Randomized Trial: Hippocampal Avoidance During Whole-Brain Radiotherapy for Patients with Brain Metastases

10 Mar, 2020 | 10:17h | UTC

Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001 – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentaries: Hippocampal avoidance during WBRT reduces risks on NRG Oncology trial – NRG Oncology (free) AND ‘Practice-Changing’ Study on WBRT for Patients With Brain Mets – Medscape (free registration required)

 


ASTRO Guideline: Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin

21 Jan, 2020 | 01:35h | UTC

Definitive and Postoperative Radiation Therapy for Basal and Squamous Cell Cancers of the Skin: Executive Summary of an American Society for Radiation Oncology Clinical Practice Guideline – Practical Radiation Oncology (free)

Commentary: ASTRO Issues Clinical Guideline on Radiation Therapy for Basal Cell and Cutaneous Squamous Cell Carcinomas – The ASCO Post (free)

 


Observational Study: Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation for Localized Prostate Cancer

16 Jan, 2020 | 08:53h | UTC

Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer – JAMA (free for a limited period)

Related Study: Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received (free)

Commentaries: Prostatectomy-associated urinary incontinence disparities persist at 5 years – MedwireNews (free) AND Prostate Cancer Treatment Side Effects Worse With Prostatectomy – Renals & Urology News (free)

 


[Abstract Only] Randomized Trial: External Beam Accelerated Partial Breast Irradiation vs. Whole Breast Irradiation after Breast Conserving Surgery in Women with Ductal Carcinoma in Situ and Node-negative Breast Cancer

5 Jan, 2020 | 13:08h | UTC

External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Results mixed for twice-daily APBI in early breast cancer – MedicalXpress (free)

 

Related Commentary on Twitter

 


[Abstract Only] Randomized Trial: Accelerated Partial Breast Irradiation vs. Whole-breast Irradiation After Breast-conserving Surgery for Early-stage Breast Cancer

5 Jan, 2020 | 13:05h | UTC

Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial – The Lancet (link to abstract – $ for full-text)

 

Related Commentary on Twitter


Randomized Trial: Single-Fraction vs. Multifraction Radiotherapy for Spinal Canal Compression from Metastatic Cancer

4 Dec, 2019 | 08:18h | UTC

Effect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: One dose of radiotherapy as effective as five doses for cancer in the spine – University College London (free)

 


Randomized Trial: Synchronous vs. Sequential Chemo-radiotherapy in Patients with Early Stage Breast Cancer

4 Dec, 2019 | 08:17h | UTC

Synchronous versus sequential chemo-radiotherapy in patients with early stage breast cancer (SECRAB): A randomised, phase III, trial – Radiation & Oncology (free)

 


Ten-year Outcomes in Men with Localized Prostate Cancer from the ProtecT Randomized Controlled Trial According to Treatment Received

29 Nov, 2019 | 08:24h | UTC

Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received – European Urology (free)

Original Study: 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer – New England Journal of Medicine (free)

 

Related Commentary on Twitter

 


Meta-Analysis: Early vs. Delayed Surgery After Short-course Radiotherapy for Rectal Cancer

24 Nov, 2019 | 20:41h | UTC

Early versus delayed surgery after short-course radiotherapy for rectal cancer: A network meta-analysis of randomized Controlled Trials – Asian Journal of Surgery (free)

 


Deep Learning: A Review for the Radiation Oncologist

29 Oct, 2019 | 02:16h | UTC

Deep Learning: A Review for the Radiation Oncologist – Frontiers in Oncology (free)

 


Perspective: Alternative Payment for Radiation Oncology

10 Oct, 2019 | 09:15h | UTC

Alternative Payment for Radiation Oncology – JAMA (free for a limited period)

 


#ESMO19 – [Not Published Yet] Randomized Trial: Many Men with Prostate Cancer May Avoid Postoperative Radiotherapy, Study Suggests

30 Sep, 2019 | 00:39h | UTC

Men with Prostate Cancer can be Spared Radiotherapy after Surgery [ESMO 2019 Press Release] (free)

See also: ESMO 2019: Men With Prostate Cancer May Avoid Postoperative Radiotherapy, Study Finds – The ASCO Post (free) AND Skipping Radiotherapy After Surgery for Prostate Cancer – Medscape (free registration required)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

 


ASTRO Guideline: Radiation Therapy for Pancreatic Cancer

12 Sep, 2019 | 08:01h | UTC

Radiation Therapy for Pancreatic Cancer: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology (free)

Commentaries: ASTRO Guideline on Use of Radiation Therapy for Patients With Pancreatic Cancer – The ASCO Post (free) AND New guideline clarifies role of radiation therapy in pancreatic cancer treatment – American Society for Radiation Oncology (free)

 


[Abstract Only] Randomized Trial: Adjuvant Radiotherapy Following Radical Prostatectomy vs. Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension

10 Sep, 2019 | 00:56h | UTC

Randomised Trial of Adjuvant Radiotherapy Following Radical Prostatectomy Versus Radical Prostatectomy Alone in Prostate Cancer Patients with Positive Margins or Extracapsular Extension – European Urology (link to abstract – $ for full-text)

Commentaries: Adjuvant Radiotherapy After Radical Prostatectomy vs Radical Prostatectomy Alone in Patients With Positive Margins or Extracapsular Extension – The ASCO Post (free) AND Adjuvant radiotherapy may be beneficial in treating locally advanced prostate cancer – University of Helsinki (free)

Source: EvidenceAlerts

 


Systematic Review: Hypofractionation (Fewer, Larger Doses of Daily Radiation) for Clinically Localized Prostate Cancer Results in Similar Oncologic Outcomes

8 Sep, 2019 | 23:00h | UTC

Hypofractionation for clinically localized prostate cancer – Cochrane Library (free)

 


Randomized Trial: Neoadjuvant Radiotherapy for Resectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombus

27 Aug, 2019 | 00:09h | UTC

Neoadjuvant Three-Dimensional Conformal Radiotherapy for Resectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombus: A Randomized, Open-Label, Multicenter Controlled Study – Journal of Clinical Oncology (free)

Commentary: Neoadjuvant Radiotherapy vs Surgery Alone for Resectable Hepatocellular Carcinoma With Tumor Thrombus – The ASCO Post (free)

Source: EvidenceAlerts

 


Brachytherapy: An Overview for Clinicians

25 Aug, 2019 | 21:09h | UTC

Brachytherapy: An overview for clinicians – CA: A Cancer Journal for Clinicians (free)

 


Study: Association of Radioactive Iodine Treatment With Cancer Mortality in Patients With Hyperthyroidism

2 Jul, 2019 | 06:20h | UTC

Association of Radioactive Iodine Treatment With Cancer Mortality in Patients With Hyperthyroidism – JAMA Internal Medicine (free)

Commentaries: NIH study finds long-term increased risk of cancer death following common treatment for hyperthyroidism – NIH News Releases (free) AND Treatment for overactive thyroid linked to increased risk of dying from cancer – CNN (free) AND Expert reaction to study looking at radioactive iodine treatment for overactive thyroid and risk of cancer – Science Media Centre (free)

 


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