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TOP 10 Medical News Stories

Fri August 14 – 10 Stories of The Day!

14 Aug, 2020 | 00:01h | UTC


1 – Methylprednisolone as Adjunctive Therapy for Patients Hospitalized With COVID-19 (Metcovid): A Randomised, Double-Blind, Phase IIb, Placebo-Controlled Trial – Clinical Infectious Diseases

Related Study: Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report – New England Journal of Medicine


2 – There’s ‘No Evidence’ Of Foodborne Transmission Of COVID-19, Says WHO – Health Policy Watch

Related: You Probably Won’t Catch the Coronavirus From Frozen Food – The New York Times


3 – Fauci Says Coronavirus Temperature Checks ‘Notoriously Inaccurate’ – Forbes

Related: Paging Dr. Hamblin: Everyone Wants to Check My Temperature – The Atlantic


4 – Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes: Interim Analysis of 2 Randomized Clinical Trials – JAMA


5 – These Covid-19 vaccine candidates could change the way we make vaccines — if they work – Vox


6 – Effect of Convalescent Plasma on Mortality among Hospitalized Patients with COVID-19: Initial Three-Month Experience – medRxiv

Commentary: Large study suggests convalescent plasma can help treat Covid-19, but experts have doubts – STAT


7 – Contact Settings and Risk for Transmission in 3410 Close Contacts of Patients With COVID-19 in Guangzhou, China: A Prospective Cohort Study – Annals of Internal Medicine


8 – Coagulopathy in COVID-19: Manifestations and management – Cleveland Clinic Journal of Medicine


9 – Development and validation of a model for individualized prediction of hospitalization risk in 4,536 patients with COVID-19 – PLOS One

Commentary: New prediction model can forecast personalized risk for COVID-19-related hospitalization – MedicalXpress

Online risk calculator: Predict Hospitalization Risk for COVID-19 Positive


10 –COVID-19 Updates / 14 August 2020 Edition

14 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Thu August 13 – 10 Stories of The Day!

13 Aug, 2020 | 00:29h | UTC


1 – AVIFAVIR for Treatment of Patients with Moderate COVID-19: Interim Results of a Phase II/III Multicenter Randomized Clinical Trial – Clinical Infectious Diseases


2 – Laboratory features of severe vs. non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis – European Journal of Medical Research


3 – Russia’s Rapid COVID-19 Vaccine Approval Draws Intense Criticism From Some – And Offers To Collaborate From Others – Health Policy Watch


4 – Extracorporeal Membrane Oxygenation for Patients With COVID-19 in Severe Respiratory Failure – JAMA Surgery


5 – Diagnostic Performance of Chest CT for SARS-CoV-2 Infection in Individuals with or without COVID-19 Symptoms – Radiology


6 – Digital public health and COVID-19 – The Lancet Public Health


7 – Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients – medRxiv

Commentaries: Viable SARS-CoV-2 aerosols detected in a hospital room with COVID-19 patients – News Medical AND ‘A Smoking Gun’: Infectious Coronavirus Retrieved From Hospital Air – The New York Times


8 – Association Between Youth Smoking, Electronic Cigarette Use, and Coronavirus Disease 2019 – Journal of Adolescent Health

Commentary: Vaping linked to COVID-19 risk in teens and young adults, study finds – Stanford Medicine


9 – The pandemic appears to have spared Africa so far. Scientists are struggling to explain why – Science


10 –COVID-19 Updates / 13 August 2020 Edition

13 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Wed August 12 – 10 Stories of The Day!

12 Aug, 2020 | 02:43h | UTC


1 – Management of post-acute covid-19 in primary care – The BMJ

Commentary: We Need to Take Care of the Growing Number of Long-term COVID-19 Patients – TIME


2 – Track COVID-19 sickness, not just positive tests and deaths – Nature


3 – Antibody therapies could be a bridge to a coronavirus vaccine — but will the world benefit? – Nature

Related: Antibody drugs could be one of the best weapons against Covid-19. But will they matter? – STAT AND Designer antibodies could battle COVID-19 before vaccines arrive – Science


4 – Filtration Efficiency of Hospital Face Mask Alternatives Available for Use During the COVID-19 Pandemic – JAMA Internal Medicine

Editorial: Filtration Efficiency, Effectiveness, and Availability of N95 Face Masks for COVID-19 Prevention

Commentary: Sanitized N95s acceptable alternatives to new masks, JAMA study finds – Healthcare Dive


5 – Putin says Russia has approved ‘world first’ Covid-19 vaccine. But questions over its safety remain – CNN

See also: Russia has launched the world’s first COVID-19 vaccine: Here’s all you need to know – Firstpost AND Coronavirus: Putin says vaccine has been approved for use – BBC AND Russia Approves Coronavirus Vaccine Before Completing Tests – The New York Times AND The Russian Vaccine – Science Translational Medicine AND Russia claims first coronavirus vaccine as global cases top 20 million – MedicalXpress


6 – Delay routine dental checkups, WHO urges, until COVID risk is known – Reuters

Related WHO Guidance: Considerations for the provision of essential oral health services in the context of COVID-19 – World Health Organization


7 – Managing Hyperglycemia in the COVID-19 Inflammatory Storm – Diabetes


8 – A Pragmatic Approach to Inpatient Diabetes Management during the COVID-19 Pandemic – The Journal of Clinical Endocrinology & Metabolism


9 – Risk to health from COVID‐19 for anaesthetists and intensivists – a narrative review – Anaesthesia


10 –COVID-19 Updates / 12 August 2020 Edition

12 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Tue August 11 – 10 Stories of The Day!

11 Aug, 2020 | 10:31h | UTC


1 – COncise adVice on Inpatient Diabetes (COVID:Diabetes) – Diabetes UK

Commentary: Guidance Covers Glycemia in Dexamethasone-Treated COVID-19 – Medscape (free registration required)

See also: COVID-19 (Coronavirus) Information for Healthcare Professionals – Association of British Clinical Diabetologists


2 – Myasthenia Gravis Associated With SARS-CoV-2 Infection – Annals of Internal Medicine


3 – Covid-19 Drug Research Is a Big Huge Mess – Wired


4 – Patient-reported outcomes: central to the management of COVID-19 – The Lancet


5 – SARS-CoV-2 and the Role of Orofecal Transmission: Systematic Review – medRxiv


6 – Immunogenicity and Safety of a SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18-59 years: Report of the Randomized, Double-blind, and Placebo-controlled Phase 2 Clinical Trial – medRxiv


7 – Role of extracorporeal membrane oxygenation in COVID‐19: A systematic review – Journal of Cardiac Surgery


8 – What we are learning about Covid-19 and kids – The Guardian


9 – Reopening schools too early could spread COVID-19 even faster – especially in the developing world – World Economic Forum


10 –COVID-19 Updates / 11 August 2020 Edition

11 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Mon August 10 – 10 Stories of The Day!

10 Aug, 2020 | 02:14h | UTC


1 – Children Can Get Severe COVID-19, CDC Says — Especially Black And Hispanic Children – NPR

Original Study: Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 1–July 25, 2020 – CDC Morbidity and Mortality Weekly Report


2 – SARS-CoV-2 viral load predicts COVID-19 mortality – The Lancet Respiratory Medicine


3 – International variation in the management of severe COVID-19 patients – Critical Care


4 – Researchers created a test to determine which masks are the least effective – CNN

Original study: Low-cost measurement of facemask efficacy for filtering expelled droplets during speech – Science Advances


5 – Case Rates, Treatment Approaches, and Outcomes in Acute Myocardial Infarction During the Coronavirus Disease 2019 Pandemic – JAMA Cardiology

Commentaries: Heart attack victims may be dying because of coronavirus fears, study finds – CNN AND Hospitalizations for heart attacks drop sharply during covid pandemic –


6 – Cardiac Involvement in Patients Recovered From COVID-2019 Identified Using Magnetic Resonance Imaging – JACC: Cardiovascular Imaging

Related study: Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19) – JAMA Cardiology


7 – Saliva as a Noninvasive Specimen for Detection of SARS-CoV-2 – Journal of Clinical Microbiology


8 – Successful Elimination of Covid-19 Transmission in New Zealand – New England Journal of Medicine

Related: 100 days without COVID-19: how New Zealand got rid of a virus that keeps spreading across the world – The Conversation


9 – The Coronavirus Is New, but Your Immune System Might Still Recognize It – The New York Times


10 –COVID-19 Updates / 10 August 2020 Edition

10 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Fri August 07 – 10 Stories of The Day!

7 Aug, 2020 | 03:36h | UTC


1 – Even Asymptomatic People Carry the Coronavirus in High Amounts – The New York Times

Original Study: Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea – JAMA Internal Medicine


2 – Asymptomatic SARS-CoV-2 infections: a living systematic review and meta-analysis – medRxiv


3 – Fast, cheap tests could enable safer reopening – Science


4 – How Safe Is Your School’s Reopening Plan? Here’s What To Look For – NPR


5 – Aboard the Diamond Princess, a Case Study in Aerosol Transmission – The New York Times

Original Study [Preprint]: Mechanistic Transmission Modeling of COVID-19 on the Diamond Princess Cruise Ship Demonstrates the Importance of Aerosol Transmission – medRxiv


6 – Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection – medRxiv

Commentary: Severe fatigue common in COVID-19, independent of disease severity – News Medical


7 – COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection – Blood

Invited commentary: COVID-19 coagulopathy, thrombosis, and bleeding – Blood


8 – Three simple acts can stop Covid-19 outbreaks, study finds – CNN

Original Study: Impact of self-imposed prevention measures and short-term government-imposed social distancing on mitigating and delaying a COVID-19 epidemic: A modelling study – PLOS Medicine


9 – Pulmonary embolism: update on management and controversies – The BMJ


10 –COVID-19 Updates / 07 August 2020 Edition

07 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Thu August 06 – 10 Stories of The Day!

6 Aug, 2020 | 03:05h | UTC


1 – Use of Chest Imaging in the Diagnosis and Management of COVID-19: A WHO Rapid Advice Guide – Radiology


2 – Coronavirus Update With Soumya Swaminathan from the WHO – JAMA


3 – How the pandemic might play out in 2021 and beyond – Nature


4 – T cell responses in patients with COVID-19 – Nature Reviews Immunology


5 – Immunology Is Where Intuition Goes to Die – The Atlantic


6 – Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study – The Lancet Public Health

Commentary: Health workers, especially minorities, at high risk for COVID, even with PPE – CIDRAP


7 – Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial – The Lancet

Commentary: Reducing corticosteroid use in rheumatoid arthritis – Charité – Universitätsmedizin Berlin


8 – Heart Failure With Reduced Ejection Fraction: A Review – JAMA (free for a limited period)

Podcast: Update on Congestive Heart Failure – JAMA


9 – The global burden of disease attributable to high body mass index in 195 countries and territories, 1990–2017: An analysis of the Global Burden of Disease Study – PLOS Medicine


10 –COVID-19 Updates / 06 August 2020 Edition

06 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Wed August 05 – 10 Stories of The Day!

5 Aug, 2020 | 10:14h | UTC


1 – Nine Important Things We’ve Learned about the Coronavirus Pandemic So Far – Scientific American


2 – Why pregnant women face special risks from COVID-19 – Science


3 – “Is It Safe for Me to Go to Work?” Risk Stratification for Workers during the Covid-19 Pandemic – New England Journal of Medicine


4 – SARS-CoV-2 (COVID-19) serology: implications for clinical practice, laboratory medicine and public health – Canadian Medical Association Journal


5 – Those with milder COVID-19 may not shed live virus as long – CIDRAP

Original Study: SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease – CDC Emerging Infectious Diseases


6 – How to Think Like an Epidemiologist – The New York Times


7 – Coronavirus vaccine tracker: how close are we to a vaccine? – The Guardian

Related: Coronavirus Vaccine Tracker – The New York Times


8 – Exposure to common cold coronaviruses can teach the immune system to recognize SARS-CoV-2 – La Jolla Institute for Immunology

Original Study: Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans – Science


9 – REGN-COV2 antibody cocktail prevents and treats SARS-CoV-2 infection in rhesus macaques and hamsters – bioRxiv

Commentaries: Regeneron’s Monoclonal Antibody Cocktail in Primates – Science Translational Medicine AND Regeneron antibody cocktail shows promise as potential COVID-19 treatment – News Medical


10 –COVID-19 Updates / 05 August 2020 Edition

05 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Tue August 04 – 10 Stories of The Day!

4 Aug, 2020 | 03:27h | UTC


1 – The Stanford Hall consensus statement for post-COVID-19 rehabilitation – British Journal of Sports Medicine


2 – Long term respiratory complications of covid-19 – The BMJ


3 – Anxiety and depression in COVID-19 survivors: role of inflammatory and clinical predictors – Brain, Behavior and Immunity

Commentary: Survivors of Covid-19 show increased rate of psychiatric disorders, study finds – The Guardian


4 – Cerebral Micro-Structural Changes in COVID-19 Patients – An MRI-based 3-month Follow-up Study – EClinicalMedicine


5 – Coronavirus Q&A With Anthony Fauci – JAMA


6 – Cloth face masks can reduce the spread of SARS-CoV-2 – Karolinska Institutet

Original Study: Forgotten Technology in the COVID-19 Pandemic. Filtration Properties of Cloth and Cloth Masks: A Narrative Review – Mayo Clinic Proceedings


7 – Use of facemasks during the COVID-19 pandemic – The Lancet Respiratory Medicine

Related: How masks work: It’s simple arithmetic – Daily Hampshire Gazette


8 – More Marketing than medical evidence: infrared thermometers to screen for COVID-19 – CEBM Oxford


9 – Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection – Nature Medicine

Commentary: Ancient part of immune system may underpin severe COVID – Columbia University Irving Medical Center


10 –COVID-19 Updates / 04 August 2020 Edition

04 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Mon August 03 – 10 Stories of The Day!

3 Aug, 2020 | 01:12h | UTC


1 – Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ


2 – Cellular immune responses to covid-19 – The BMJ


3 – COVID-19 pandemic personal protective equipment (PPE): Guidance for intensive care – Intensive Care Society


4 – Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS – Intensive Care Medicine


5 – From ‘brain fog’ to heart damage, COVID-19’s lingering problems alarm scientists – Science


6 – Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil – Nature Human Behaviour


7 – Opinion – ‘This Push to Open Schools Is Guaranteed to Fail’ – The Atlantic

“Within two weeks of opening schools in communities with high virus transmission, teachers will become ill. All it will take is for a single teacher to become hospitalized with COVID and everything will shut down.”


8 – SARS-CoV-2 Transmission and Infection Among Attendees of an Overnight Camp — Georgia, June 2020 – CDC – Morbidity and Mortality Weekly Report (MMWR)

Commentaries: The Coronavirus Infected Hundreds at a Georgia Summer Camp – The New York Times AND How At Least 44% Of Young People At A Summer Camp Caught Coronavirus – Forbes


9 – Assessment of SARS-CoV-2 Screening Strategies to Permit the Safe Reopening of College Campuses in the United States – JAMA Network Open

Commentaries: Researchers offer ways to promote safety when reopening colleges – CIDRAP AND New Study: College Students Who Get Tested Every Two Days Can Return To Campus Safely – Forbes


10 –COVID-19 Updates / 03 August 2020 Edition

03 August 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Fri July 31 – 10 Stories of The Day!

31 Jul, 2020 | 09:02h | UTC


1 – Remdesivir for severe covid-19: a clinical practice guideline – The BMJ


2 – Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19) – JAMA Pediatrics

Commentaries: Young kids could spread COVID-19 as much as older children and adults, study suggests – Ann & Robert H. Lurie Children’s Hospital of Chicago AND Study finds higher viral load in young children, raising questions about how likely they are to transmit the coronavirus – CNN AND Children May Carry Coronavirus at High Levels, Study Finds – The New York Times


3 – COVID-19 and Dexamethasone: A Potential Strategy to Avoid Steroid-Related Strongyloides Hyperinfection – JAMA


4 – SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19 – Nature

Commentaries: Could prior exposure to common cold viruses affect the severity of SARS-CoV-2 symptoms? – Charité – Universitätsmedizin Berlin AND Why some people who haven’t had Covid-19 might already have some immunity – CNN


5 – Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques – Nature

Commentaries: Vaccine Candidate Delivers Protection In A Single Shot (In Monkeys) – NPR AND Novel vaccine candidate robustly protects non-human primates against SARS-CoV-2 – News Medical


6 – Study: Travel to 3 countries may have seeded COVID-19 pandemic – CIDRAP

Original study: Observations of the global epidemiology of COVID-19 from the prepandemic period using web-based surveillance: a cross-sectional analysis – The Lancet Infectious Diseases


7 – COVID-19 pandemic is “one big wave” says WHO – News Medical

See also: ‘One big wave’ – why the Covid-19 second wave may not exist – The Guardian


8 – Things you should think about when you hear “vaccine by end of the year” – Health News Review


9 – ‘A huge experiment’: How the world made so much progress on a Covid-19 vaccine so fast – STAT


10 –COVID-19 Updates / 31 July 2020 Edition

31 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Thu July 30 – 10 Stories of The Day!

30 Jul, 2020 | 10:55h | UTC


1 – Roche provides an update on the phase III COVACTA trial of Actemra/RoActemra in hospitalised patients with severe COVID-19 associated pneumonia


2 – Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US – JAMA

Editorial: COVID-19 and School Closures

Author Interview: COVID-19 and School Reopenings

Commentaries: School closures in spring linked to drastic decrease in Covid-19 cases and deaths – STAT AND Schools closures in spring were linked to reductions in Covid-19 cases and deaths, study says – CNN AND Closing schools in March may have saved the lives of 40,000 Americans, a new analysis found – Business Insider AND School Closures in the Spring Saved Lives, Study Asserts – The New York Times


3 – Reopening K-12 Schools During the COVID-19 Pandemic: A Report From the National Academies of Sciences, Engineering, and Medicine – JAMA

Original report: Reopening K-12 Schools During the COVID-19 Pandemic – National Academies of Sciences, Engineering, and Medicine


4 – How Schools & Parents Should Navigate Reopening During COVID-19 – Infectious Diseases Society of America


5 – Reopening Primary Schools during the Pandemic – New England Journal of Medicine


6 – Opening Schools Won’t Be Easy, but Here’s How to Do It Safely – The New York Times


7 – What Do We Know About Children and Coronavirus Transmission? – Kaiser Family Foundation


8 –  Swabs Collected by Patients or Health Care Workers for SARS-CoV-2 Testing – New England Journal of Medicine


9 – SARS-CoV-2 viral load dynamics, duration of viral shedding and infectiousness: a living systematic review and meta-analysis – medRxiv


10 –COVID-19 Updates / 30 July 2020 Edition

30 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Wed July 29 – 10 Stories of The Day!

29 Jul, 2020 | 09:54h | UTC


1 – Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates – New England Journal of Medicine

Commentary: Experimental COVID-19 vaccine protects upper and lower airways in nonhuman primates – National Institutes of Health


2 – Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study – The Lancet Respiratory Medicine

Commentary: Mortality in COVID-19 is not merely a question of resource availability – The Lancet Respiratory Medicine


3 – Epidemiology of invasive pulmonary aspergillosis among COVID-19 intubated patients: a prospective study – Clinical Infectious Diseases


4 – Ecology and economics for pandemic prevention – Science

Commentaries: Cost of preventing next pandemic ‘equal to just 2% of Covid-19 economic damage’ – The Guardian AND Report: Cost Of Preventing The Next Pandemic Will Be Just 2% Of Covid-19’s Economic Damage [Infographic] – Forbes AND 3 ways to prevent the next pandemic with nature, according to science – Conservation International


5 – Viral RNA level, serum antibody responses, and transmission risk in discharged COVID-19 patients with recurrent positive SARS-CoV-2 RNA test results: a population-based observational cohort study – medRxiv


6 – Management of Infants Born to Mothers with Suspected or Confirmed COVID-19 – American Academy of Pediatrics

Commentary: AAP no longer recommends separating newborns from mothers with COVID-19 – Healio (free registration required)


7 – Coronavirus (COVID-19) Testing – Our World in Data


8 – Longitudinal analyses reveal immunological misfiring in severe COVID-19 – Nature

Commentary: Immune system variation can predict severe COVID-19 outcomes – Yale University


9 – Sodium–Glucose Cotransporter-2 Inhibitors and the Risk for Diabetic Ketoacidosis: A Multicenter Cohort Study – Annals of Internal Medicine

Commentary: Sodium glucose cotransporter-2 inhibitor use associated with increased risk of diabetic ketoacidosis – 2 Minute Medicine


10 –COVID-19 Updates / 29 July 2020 Edition

29 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Tue July 28 – 10 Stories of The Day!

28 Jul, 2020 | 08:08h | UTC


1 – Infectious Diseases Society of America Guidelines on Infection Prevention for Health Care Personnel Caring for Patients with Suspected or Known COVID-19 – Clinical Infectious Diseases


2 – Respiratory support in patients with COVID-19 (outside intensive care unit). A position paper of the Respiratory Support and Chronic Care Group of the French Society of Respiratory Diseases


3 – Respiratory Mechanics of COVID-19– versus Non–COVID-19–associated Acute Respiratory Distress Syndrome – American Journal of Respiratory and Critical Care Medicine


4 – Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19) – JAMA Cardiology

Related Study: Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases – JAMA Cardiology

Editorial: Coronavirus Disease 2019 (COVID-19) and the Heart—Is Heart Failure the Next Chapter? – JAMA Cardiology

Commentaries: Research reveals heart complications in COVID-19 patients – CIDRAP AND 78% of COVID-19 patients show signs of heart damage after recovery – Cardiovascular Business


5 – Characteristics and Strength of Evidence of COVID-19 Studies Registered on – JAMA Internal Medicine

Editorial: Setting Expectations for Clinical Research During the COVID-19 Pandemic

Commentary: Large proportion of COVID-19 studies have low-level evidence – MedicalXpress


6 – Covidization of research: what are the risks? – Nature Medicine


7 – Assessing the extent of SARS-CoV-2 circulation through serological studies – Nature Medicine


8 – A Vaccine Reality Check – The Atlantic


9 – Covid-19 vaccines may cause mild side effects, experts say, stressing need for education, not alarm – STAT


10 –COVID-19 Updates / 28 July 2020 Edition

28 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Mon July 27 – 10 Stories of The Day!

27 Jul, 2020 | 10:08h | UTC


1 – A Cluster-Randomized Trial of Hydroxychloroquine as Prevention of Covid-19 Transmission and Disease – medRxiv


2 – Presence of Genetic Variants Among Young Men With Severe COVID-19 – JAMA

Editorial: Molecular Underpinnings of Severe Coronavirus Disease 2019

Commentary: Genetic mutations predispose individuals to severe COVID-19 – Radboud University


3 – COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives – Nature Reviews Cardiology


4 – Multimodality Imaging in Evaluation of Cardiovascular complications in Patients with COVID-19 – Journal of the American College of Cardiology

Commentary: Which Modality and When? New Guidance for Cardiac Imaging in COVID-19 – TCTMD


5 – Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network — United States, March–June 2020 – CDC Morbidity and Mortality Weekly Report

Commentary: Covid-19 Can Cause ‘Prolonged Illness And Persistent Symptoms’ Even In Young People: Study – Forbes


6 – Anosmia and loss of smell in the era of covid-19 – The BMJ


7 – Particle sizes of infectious aerosols: implications for infection control – The Lancet Respiratory Medicine


8 – Which mask works best? We filmed people coughing and sneezing to find out – The Conversation

Original Study: Face coverings and mask to minimise droplet dispersion and aerosolisation: a video case study – Thorax


9 – Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study – The Lancet Child & Adolescent Health

Commentaries: Covid-19 and breastfeeding: Moms unlikely to pass virus to newborns with proper safety techniques – CNN AND Management of mother–newborn dyads in the COVID-19 era – The Lancet Child & Adolescent Health


10 –COVID-19 Updates / 27 July 2020 Edition

27 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Fri July 24 – 10 Stories of The Day!

24 Jul, 2020 | 09:38h | UTC


1 – Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19 – New England Journal of Medicine

Commentary: Another study finds hydroxychloroquine does not help Covid-19 patients – CNN


2 – Evolution and epidemic spread of SARS-CoV-2 in Brazil – Science

Commentary: COVID-19 in Brazil: Research reveals how epidemic spread around country – Imperial College London


3 – The impact of COVID-19 and strategies for mitigation and suppression in low- and middle-income countries – Science

Commentaries: LMICs will face ‘extreme strain’ on health systems despite younger populations – Imperial College London AND Is COVID-19 magnifying colonial attitudes in global health? – Devex AND New modeling study evaluates impact of COVID-19 in low- and middle-income countries – News Medical


4 – A large COVID-19 outbreak in a high school 10 days after schools’ reopening, Israel, May 2020 – Eurosurveillance


5 – Coronavirus Update With Eric Topol – JAMA


6 – Covid-19 Patients No Longer Need Tests to End Isolation – The New York Times

Original CDC Guidance: Duration of Isolation and Precautions for Adults with COVID-19 – Centers for Disease Control and Prevention


7 – Trusting evidence over anecdote: Clinical decision making in the era of covid-19 – The BMJ Opinion


8 – Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers: A Living Rapid Review – Annals of Internal Medicine


9 – Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis – Clinical Microbiology and Infection


10 –COVID-19 Updates / 24 July 2020 Edition

24 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Thu July 23 – 10 Stories of The Day!

23 Jul, 2020 | 08:51h | UTC


1 – Effect of Systemic Glucocorticoids on Mortality or Mechanical Ventilation in Patients With COVID-19 – Journal of Hospital Medicine

Commentaries: A blood test may show which COVID-19 patients steroids will help — or harm – Science News AND Common blood test identifies benefits and risks of steroid treatment in COVID-19 patients – Albert Einstein College of Medicine


2 – Managing uncertainty in the covid-19 era – The BMJ Opinion


3 – Audio Interview: Dexamethasone and Covid-19 – New England Journal of Medicine


4 – Rapid Scaling Up of Covid-19 Diagnostic Testing in the United States — The NIH RADx Initiative – New England Journal of Medicine


5 – Coronavirus vaccines leap through safety trials — but which will work is anybody’s guess – Nature


6 – Covid-19 Vaccines With ‘Minor Side Effects’ Could Still Be Pretty Bad – Wired


7 – Controversial ‘human challenge’ trials for COVID-19 vaccines gain support – Science


8 – How to Understand COVID-19 Numbers – ProPublica


9 – COVID-19 Serological Tests: How Well Do They Actually Perform? – Diagnostics

Commentary: Overview of Covid-19 Serological Tests –


10 –COVID-19 Updates / 23 July 2020 Edition

23 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Wed July 22 – 10 Stories of The Day!

22 Jul, 2020 | 02:38h | UTC


1 – The RECOVERY Platform – New England Journal of Medicine


2 – Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19 – New England Journal of Medicine


3 – Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020 – JAMA Internal Medicine

Editorial: Serosurveillance and the COVID-19 Epidemic in the US: Undetected, Uncertain, and Out of Control – JAMA

Commentaries: Actual Covid-19 case count could be 6 to 24 times higher than official estimates, CDC study shows – STAT AND Coronavirus Infections Much Higher Than Reported Cases in Parts of U.S., Study Shows – The New York times


4 – Community prevalence of SARS-CoV-2 virus in England during May 2020: REACT study – medRxiv

Commentary: Expert reaction to preprint (not a published paper) from the REACT study on community prevalence of SARS-CoV-2 – Science Media Centre


5 – Impact of delays on effectiveness of contact tracing strategies for COVID-19: a modelling study – The Lancet Public Health

Commentaries: Quick testing is needed for coronavirus contact tracing to be most effective, research finds – CNN AND Speed of testing is most critical factor in the success of contact tracing strategies to slow COVID-19 transmission – The Lancet AND Expert reaction to paper looking at COVID-19 contact tracing strategies and speed of testing – Science Media Centre AND Can digital contact tracing make up for lost time? – The Lancet Public Health


6 – Care of the pregnant woman with coronavirus disease 2019 in labor and delivery: anesthesia, emergency cesarean delivery, differential diagnosis in the acutely ill parturient, care of the newborn, and protection of the healthcare personnel – American Journal of Obstetrics & Gynecology


7 – Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study – medRxiv


8 – Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with COVID-19 in New York City – The Journal of Pediatrics


9 – SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls – Nature

Commentaries: New Data on T Cells and the Coronavirus – Science Translational Medicine AND Scientists uncover SARS-CoV-2-specific T cell immunity in recovered COVID-19 and SARS patients – Duke-NUS Medical School AND Expert reaction to study looking at SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS and uninfected controls from data from Singapore – Science Media Centre


10 –COVID-19 Updates / 22 July 2020 Edition

22 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Tue July 21 – 10 Stories of The Day!

21 Jul, 2020 | 09:36h | UTC


1 – Encouraging results from phase 1/2 COVID-19 vaccine trials – The Lancet

Podcast: The Lancet Editor-in-Chief Richard Horton explains the current status of the Oxford and China COVID-19 vaccines

Commentaries: Promising early findings for 2 more COVID-19 vaccines – CIDRAP AND Expert reaction to two vaccine candidate studies: a phase 1/2 trial of the University of Oxford’s ChAdOx1 vaccine candidate; and a phase 2 trial of China’s Ad5-vectored COVID-19 vaccine candidate – Science Media Centre


2 – Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial – The Lancet

Commentaries: New study reveals Oxford coronavirus vaccine produces strong immune response – University of Oxford AND Oxford’s Covid-19 vaccine appears safe and induces immune response, early results suggest, but more research is needed – CNN AND Early Oxford-AstraZeneca Coronavirus Vaccine Data ‘Encouraging,’ Scientists Say – NPR


3 – Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial – The Lancet

Commentaries: China’s Ad5 vectored COVID-19 vaccine safe and induces immune response – News Medical AND CanSino COVID-19 vaccine generates immune response in 90% of patients – UPI


4 – Synairgen announces positive results from trial of SNG001 in hospitalised COVID-19 patients

Commentaries: New Treatment for Covid-19 Shows Promise, but Scientists Urge Caution – The New York Times AND Expert reaction to announcement by Synairgen that their drug SNG001 has had positive results in initial trials on COVID-19 patients – Science Media Centre AND Trial of Covid-19 drug given via inhaler ‘very promising’, say scientists – The Guardian


5 – Symptom clusters in Covid19: A potential clinical prediction tool from the COVID Symptom study app – medRxiv

Commentaries: Covid-19: Study reveals six clusters of symptoms that could be used as a clinical prediction tool – The BMJ AND Six distinct ‘types’ of COVID-19 identified – King’s College London AND Coronavirus symptoms fall into six different groupings, study finds – The Guardian


6 – Survivorship after COVID-19 ICU stay – Nature Reviews


7 – Ketoacidosis in Children and Adolescents With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic in Germany – JAMA


8 – Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System – JAMA


9 – The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study – The Lancet Oncology


10 –COVID-19 Updates / 21 July 2020 Edition

21 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Mon July 20 – 10 Stories of The Day!

20 Jul, 2020 | 08:22h | UTC


1 – Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report – New England Journal of Medicine

Commentary: Trial data support dexamethasone, but not hydroxychloroquine, for COVID-19 – CIDRAP


2 – Research in the Context of a Pandemic – New England Journal of Medicine


3 – Contact Tracing during Coronavirus Disease Outbreak, South Korea, 2020 – CDC Emerging Infectious Diseases

Commentaries: Older Children Spread the Coronavirus Just as Much as Adults, Large Study Finds – The New York Times AND Children over age 10 spread COVID-19 as much as adults, study finds – CTV


4 – The role of chest radiography in confirming covid-19 pneumonia – The BMJ


5 – What counts as a covid-19 death? – The BMJ


6 – Policy Responses to the Coronavirus Pandemic – Our World in Data


7 – Benefits of routine childhood vaccines far outweigh risks of additional COVID-19 transmission in Africa, modelling study suggests – London School of Hygiene & Tropical Medicine

Original Study: Routine childhood immunisation during the COVID-19 pandemic in Africa: a benefit–risk analysis of health benefits versus excess risk of SARS-CoV-2 infection – The Lancet Global Health


8 – COVID-19 in people with diabetes: understanding the reasons for worse outcomes – The Lancet Diabetes & Endocrinology

Related: New-Onset Diabetes in Covid-19 – New England Journal of Medicine


9 – Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series – The Lancet


10 –COVID-19 Updates / 20 July 2020 Edition

20 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Fri July 17 – 10 Stories of The Day!

17 Jul, 2020 | 09:01h | UTC


1 – RIP Hydroxychloroquine? 2 studies show no benefit in early/mild COVID-19

Study 1: Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19: A Randomized Trial – Annals of Internal Medicine

Study 2: Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial – Clinical Infectious Diseases

Commentaries: Hydroxychloroquine also doesn’t help Covid-19 patients who aren’t hospitalized, new study finds – CNN AND New Covid-19 study, despite flaws, adds to case against hydroxychloroquine – STAT


2 – Palliative care for patients with severe covid-19 – The BMJ


3 – How effective does a COVID-19 coronavirus vaccine need to be to stop the pandemic? A new study has answers – The Conversation

Original Study: Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention – American Journal of Preventive Medicine


4 – Challenge Trials for COVID-19 – 1 Day Sooner

Commentary: Scientists call for volunteers to be infected with the coronavirus to test vaccines – CNBC


5 – Coronavirus Drug and Treatment Tracker – The New York Times


6 – What happens if Covid-19 symptoms don’t go away? Doctors are trying to figure it out – Vox


7 – Coronavirus: why are some people experiencing long-term fatigue? – The Conversation


8 – How deadly is the coronavirus? The true fatality rate is tricky to find, but researchers are getting closer – The Conversation


9 – Social Isolation—the Other COVID-19 Threat in Nursing Homes – JAMA


10 –COVID-19 Updates / 17 July 2020 Edition

17 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Thu July 16 – 10 Stories of The Day!

16 Jul, 2020 | 08:40h | UTC


1 – Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial – medRxiv


2 – WHO and UNICEF warn of a decline in vaccinations during COVID-19 – World Health Organization

Commentary: Officials warn about drop in childhood vaccination due to COVID-19 – CIDRAP


3 – Physical distancing interventions and incidence of coronavirus disease 2019: natural experiment in 149 countries – The BMJ

Editorial: Lockdown-type measures look effective against covid-19


4 – Covid-19: Experts criticise claim that remdesivir cuts death rates – The BMJ


5 – Covid-19: an opportunity to reduce unnecessary healthcare – The BMJ

Commentary: ED volume recoveries are sluggish. That might not be a bad thing – Health Leaders


6 – Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection risk during elective peri‐operative care: a narrative review – Anaesthesia


7 – COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England – The Lancet

Commentaries: About 5,000 heart attack sufferers in England missed out on lifesaving hospital treatment due to pandemic – University of Oxford AND Thousands missed heart attack treatment during pandemic – University of Leeds AND Expert reaction to paper suggesting 5000 heart attack sufferers in England did not seek treatment due to the COVID-19 pandemic – Science Media Centre


8 – Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study – The Lancet Haematology

Commentary: Coagulation disorder in COVID-19 – The Lancet Haematology


9 – Intrauterine Transmission of Sars-Cov-2 Infection in a Preterm Infant – The Pediatric Infectious Disease Journal

Commentary: COVID-19 can be transmitted in the womb, reports pediatric infectious disease journal – Wolters Kluwer Health


10 –COVID-19 Updates / 16 July 2020 Edition

16 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Wed July 15 – 10 Stories of The Day!

15 Jul, 2020 | 08:34h | UTC


1 – Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers – JAMA

Editorial: Universal Masking to Prevent SARS-CoV-2 Transmission—The Time Is Now – JAMA

Commentaries: CDC director: We can control virus in 4 to 8 weeks if everyone in the US wears a mask – Business Insider AND CDC Director: It’s Time For Universal Masking To End Covid-19 Pandemic – Forbes


2 – Coronavirus Update With CDC Director, Robert R. Redfield, MD – JAMA


3 – Absence of Apparent Transmission of SARS-CoV-2 from Two Stylists After Exposure at a Hair Salon with a Universal Face Covering Policy — Springfield, Missouri, May 2020 – CDC Morbidity and Mortality Weekly Report

Commentary: How two hairstylists with COVID-19 saw 139 clients without passing on the virus – CTV


4 – Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 in Aerosol Suspensions – CDC Emerging Infectious Diseases


5 – Coronavirus Sparks New Interest In Using Ultraviolet Light To Disinfect Indoor Air – NPR


6 – An mRNA Vaccine against SARS-CoV-2 — Preliminary Report – New England Journal of Medicine

Editorial: The Covid-19 Vaccine-Development Multiverse – New England Journal of Medicine

Commentaries: Experimental COVID-19 vaccine safe, generates immune response – NIH News Release AND First data for Moderna Covid-19 vaccine show it spurs an immune response – STAT


7 – Evidence-Based Practice for Public Health Emergency Preparedness and Response: Recommendations From a National Academies of Sciences, Engineering, and Medicine Report – JAMA

Full Report: Evidence-Based Practice for Public Health Emergency Preparedness and Response – National Academies of Sciences, Engineering, and Medicine


8 – Transplacental transmission of SARS-CoV-2 infection – Nature Communications

Commentaries: Baby Was Infected With Coronavirus in Womb, Study Reports – The New York Times AND Expert reaction to a case study which finds evidence for the potential transmission of SARS-CoV-2 via the placenta from a mother to her baby – Science Media Centre


9 – How scientific societies are weathering the pandemic’s financial storm – Nature


10 –COVID-19 Updates / 15 July 2020 Edition

15 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Tue July 14 – 10 Stories of The Day!

14 Jul, 2020 | 08:35h | UTC


1 – Researchers develop COVID-19 mortality risk calculator – News Medical

Original Study [Preprint]: COVID-19 Mortality Risk Assessment: An International Multi-Center Study – medRxiv

See Calculator: COVID Analytics


2 – Airborne Transmission of SARS-CoV-2: Theoretical Considerations and Available Evidence – JAMA

Author Interview: How Is COVID-19 Transmitted?

Related: The debate over “airborne” coronavirus spread, explained – Vox


3 – Communicating Science in the Time of a Pandemic – JAMA


4 – A New Understanding of Herd Immunity – The Atlantic

Related: A mathematical model reveals the influence of population heterogeneity on herd immunity to SARS-CoV-2 – Science


5 – Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study – The Lancet Global Health

Invited Commentary: HIV, tuberculosis, and malaria: how can the impact of COVID-19 be minimised? – The Lancet Global Health


6 – My patient caught Covid-19 twice. So long to herd immunity hopes. – Vox


7 – A perspective on potential antibody-dependent enhancement of SARS-CoV-2 – Nature


8 – Evidence-based medicine and COVID-19: what to believe and when to change – Emergency Medicine Journal


9 – Interferon-γ release assays or tuberculin skin test for detection and management of latent tuberculosis infection: a systematic review and meta-analysis – The Lancet Infectious Diseases


10 –COVID-19 Updates / 14 July 2020 Edition

14 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


Mon July 13 – 10 Stories of The Day!

13 Jul, 2020 | 00:31h | UTC


1 – Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review – JAMA


2 – Extrapulmonary manifestations of COVID-19 – Nature Medicine

Related review: Extra‐pulmonary complications of COVID‐19: a multi‐system disease? – Journal of Medical Virology


3 – The mathematical strategy that could transform coronavirus testing – Nature


4 – Mounting evidence suggests coronavirus is airborne — but health advice has not caught up – Nature


5 – WHO Concedes Airborne Transmission of SARS-CoV-2; Critics Say Advice On Masks Still Falls Short – Health Policy Watch

Related: Transmission of SARS-CoV-2: implications for infection prevention precautions – World Health Organization AND It is Time to Address Airborne Transmission of COVID-19 – Clinical Infectious Diseases


6 – Face masks and coverings for the general public: Behavioural knowledge, effectiveness of cloth coverings and public messaging – The Royal Society / The British Academy

Commentary: Oxford COVID-19 study: face masks and coverings work – act now – University of Oxford


7 – Ivermectin and COVID-19: Keeping Rigor in Times of Urgency – The American Journal of Tropical Medicine and Hygiene

Related Editorial: COVID-19 and the rush for self-medication and self-dosing with ivermectin: A word of caution – One Health


8 – COVID-19 in Children and the Dynamics of Infection in Families – Pediatrics

News Release: Study: Household COVID-19 infection rarely starts with children – American Academy o Pediatrics

Commentaries: COVID-19 Transmission and Children: The Child Is Not to Blame – Pediatrics AND Children rarely transmit COVID-19, doctors write in new commentary – University of Vermont AND Children Seem Not to Be Driving SARS-COV-2 Transmission – Physician’s Briefing


9 – Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Pandemic – JAMA


10 –COVID-19 Updates / 13 July 2020 Edition

13 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)


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