Infectious Diseases
Cohort Study: Mortality and Pulmonary Complications in Surgical Patients with Covid-19
1 Jun, 2020 | 04:02h | UTCCommentaries: Mitigating the risks of surgery during the COVID-19 pandemic – The Lancet AND COVID-19 patients who undergo surgery are at increased risk of postoperative death – University of Birmingham AND Clinicians must carefully balance risk of complications linked to SARS-CoV2 infection with risks of delaying surgery – The Lancet
Cohort Studies: Clinical Impact of COVID-19 on Patients with Cancer
1 Jun, 2020 | 04:00h | UTCStudy 1: Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study – The Lancet
Commentaries: Studies highlight COVID-19 impact on cancer patients – CIDRAP AND Cancer, coronavirus are a dangerous mix, new studies find – MedicalXpress AND Cancer, coronavirus are a dangerous mix, new studies find – Associated Press AND Cancer and COVID-19: what do we really know? – The Lancet
An Open Letter to Mehra et al and The Lancet
1 Jun, 2020 | 03:58h | UTCAn open letter to Mehra et al and The Lancet – Zenodo
See also: Disputed Hydroxychloroquine Study Brings Scrutiny to Surgisphere – The Scientist AND A Study Out of Thin Air – Medicine (Un)Censored
Perspective: Will Evidence-Based Medicine Survive COVID-19?
1 Jun, 2020 | 03:56h | UTCWill Evidence-Based Medicine Survive COVID-19? – Boston Review
Review: Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019
1 Jun, 2020 | 03:55h | UTCRelated: A Review of Neurological Complications of COVID-19 – Cureus
[Abstract Only] Meta-Analysis: Reappraisal of the Treatment Duration of Antibiotic Regimens for Acute Uncomplicated Cystitis in Adult Women
1 Jun, 2020 | 03:31h | UTCReappraisal of the treatment duration of antibiotic regimens for acute uncomplicated cystitis in adult women: a systematic review and network meta-analysis of 61 randomised clinical trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Related Commentary on Twitter
New research Article: Reappraisal of the treatment duration of antibiotic regimens for acute uncomplicated cystitis in adult women: a systematic review and network meta-analysis of 61 randomised clinical trials #UTI https://t.co/klr2k9JFI1 pic.twitter.com/K1nPd5QCxc
— The Lancet Infectious Diseases (@TheLancetInfDis) May 21, 2020
Cohort Study: Clinical Characteristics, Etiology, and Initial Management Strategy of Newly Diagnosed Periprosthetic Joint Infection
1 Jun, 2020 | 03:29h | UTC
Editorial: Shielding from Covid-19 Should be Stratified by Risk
29 May, 2020 | 03:34h | UTCShielding from covid-19 should be stratified by risk – The BMJ
Study in a Cruise Boat Showed 81% of Patients Infected with Covid-19 were Asymptomatic
29 May, 2020 | 03:31h | UTCCOVID-19: in the footsteps of Ernest Shackleton – Thorax
Commentaries: New Paper Finds Startling Number Of Asymptomatic Covid-19 Carriers – Forbes AND Asymptomatic COVID-19 cases may be more common than suspected – NBC News AND Cruise ship study hints at many ‘silent’ COVID-19 infections – The BMJ
42% of Patients with Covid-19 Asymptomatic in Study from China
29 May, 2020 | 03:29h | UTCCommentaries: 40% of COVID-19 patients may be asymptomatic as disease progresses – UPI AND How Common Are Asymptomatic Cases of COVID-19? – U.S News
Opinion: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic
29 May, 2020 | 03:27h | UTCUsing Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic – JAMA
Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity
29 May, 2020 | 03:26h | UTCConducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity – JAMA
Perspective: For Seniors, COVID-19 Sets Off A Pandemic Of Despair
29 May, 2020 | 03:23h | UTCFor Seniors, COVID-19 Sets Off A Pandemic Of Despair – Kaiser Health News
Wastewater Testing Gains Traction as a Covid-19 Early Warning System
29 May, 2020 | 03:22h | UTCWastewater testing gains traction as a Covid-19 early warning system – STAT
Related: SARS-CoV-2 RNA in wastewater anticipated COVID-19 occurrence in a low prevalence area – Water Research AND New Research Examines Wastewater to Detect Community Spread of Covid-19
Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development
29 May, 2020 | 03:19h | UTCEthical guidelines for deliberately infecting volunteers with COVID-19 – Journal of Medical Ethics
Related: Challenge trials can speed development of a Covid-19 vaccine. Planning for them needs to start now – STAT AND AstraZeneca says it may consider exposing vaccine trial participants to virus – Reuters
Ethical Guidelines for COVID-19 Tracing Apps
29 May, 2020 | 03:18h | UTCEthical guidelines for COVID-19 tracing apps – Nature
Observational Study: Many Patients with Covid-19 in the ICU Develop Thromboembolism Despite Routine Prophylaxis
29 May, 2020 | 03:17h | UTC
Study: Face Mask Use in Households May Reduce Secondary Transmission of SARS-CoV-2
29 May, 2020 | 03:15h | UTCCommentaries: Wearing face masks at home might help ward off COVID-19 spread among family members – BMJ AND Expert reaction to study looking at face masks in the home – Science Media Centre
Small Study Shows No Evidence of Secondary Transmission of COVID-19 from Children Attending School
29 May, 2020 | 03:14h | UTC
[Abstract Only] Meta-Analysis: Postoperative Continuation of Antibiotic Prophylaxis Does Not Reduce the Incidence of Surgical Site Infections
29 May, 2020 | 03:09h | UTC
WHO Interim Guidance: Clinical Management of COVID-19
28 May, 2020 | 10:02h | UTCClinical management of COVID-19 – World Health Organization
Systematic Review: Hydroxychloroquine or Chloroquine for Treatment or Prophylaxis of COVID-19
28 May, 2020 | 09:59h | UTC
Remdesivir for Covid-19: A 5-day Course is Similarly Effective as a 10-day Course
28 May, 2020 | 10:00h | UTCRemdesivir for 5 or 10 Days in Patients with Severe Covid-19 – New England Journal of Medicine
Face Coverings for the Public: Laying Straw Men to Rest, by Trisha Greenhalgh
28 May, 2020 | 09:57h | UTCFace coverings for the public: Laying straw men to rest – Journal of Evaluation in Clinical Practice
Related: Face coverings for the lay public: an alternative view – CEBM Oxford AND Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach – Annals of Internal Medicine
Unusual in 2 ways
1. "I address charges that my coauthors and I had misapplied the precautionary principle; drawn conclusions that were not supported …"
2. Best review on the essentiality of masks, debunking the naysayers
Thanks @trishgreenhalgh 👏https://t.co/wZrep7BQ8U pic.twitter.com/n052R1RvsL— Eric Topol (@EricTopol) May 27, 2020
Perspective: Reducing Transmission of SARS-CoV-2
28 May, 2020 | 09:55h | UTCReducing transmission of SARS-CoV-2 – Science