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Infectious Diseases (all articles)

2022 AHA/ACC key data elements and definitions for cardiovascular and noncardiovascular complications of COVID-19.

27 Jun, 2022 | 12:01h | UTC

2022 AHA/ACC Key Data Elements and Definitions for Cardiovascular and Noncardiovascular Complications of COVID-19: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards – Journal of the American College of Cardiology

News Release: New ACC/AHA Data Standards Address CV, Noncardiovascular Complications of COVID-19 – American College of Cardiology

 

Systematic Review: Antibiotics for uncomplicated diverticulitis.

27 Jun, 2022 | 11:56h | UTC

Antibiotics for uncomplicated diverticulitis – Cochrane Library

Summary: Antibiotics for uncomplicated diverticulitis – Cochrane Library

Related:

Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)

The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly – World Journal of Emergency Surgery

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

Elective surgical management of diverticulitis – Current Problems in Surgery

Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality

2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting – World Journal of Emergency Surgery

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis – Diseases of the Colon & Rectum

 

Commentary on Twitter

 

[Press Release – not published yet]: RCT: Sanofi-GSK report its vaccine targeted against ancestral and Beta strains had an overall efficacy of 72% against the Omicron variant.

27 Jun, 2022 | 11:52h | UTC

Press Release: Sanofi-GSK first to report a successful efficacy study against Omicron with COVID-19 Beta-containing vaccine – Sanofi

Commentaries: Bivalent COVID Vax Gets Phase III Win Against Omicron, Companies Say — Sanofi, GSK boast of 72% efficacy against Omicron variant – MedPage Today (free registration required)

 

Epidemiology of myocarditis and pericarditis following mRNA vaccination by vaccine product, schedule, and interdose interval among adolescents and adults in Ontario, Canada.

27 Jun, 2022 | 11:51h | UTC

Epidemiology of Myocarditis and Pericarditis Following mRNA Vaccination by Vaccine Product, Schedule, and Interdose Interval Among Adolescents and Adults in Ontario, Canada – JAMA Network Open

Commentary: Young Men’s Myocarditis Risk 5 Times Higher With Moderna vs Pfizer Vax — But Canadian study finds that 8-week interval before second dose attenuates some of the risk – MedPage Today (free registration required)

 

Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19.

27 Jun, 2022 | 11:49h | UTC

Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19 – The Lancet Respiratory Medicine

Commentary: Early-phase clinical trials in a pandemic: learning from the response to COVID-19 – The Lancet Respiratory Medicine

 

Commentary on Twitter

 

Perspective | What Omicron’s BA.4 and BA.5 variants mean for the pandemic.

27 Jun, 2022 | 11:48h | UTC

What Omicron’s BA.4 and BA.5 variants mean for the pandemic – Nature

 

Vaccinations may have prevented almost 20 million COVID-19 deaths worldwide.

27 Jun, 2022 | 11:46h | UTC

News Release: Vaccinations may have prevented almost 20 million COVID-19 deaths worldwide – Imperial College London

Original Study: Global impact of the first year of COVID-19 vaccination: a mathematical modelling study – The Lancet Infectious Diseases

Commentaries:

The global impact of disproportionate vaccination coverage on COVID-19 mortality – The Lancet Infectious Diseases

Covid-19 vaccines prevented nearly 20 million deaths in a year, study estimates – STAT

COVID-19 vaccines saved an estimated 20 million lives in 1 year – CIDRAP

COVID-19 Vaccines Saved Almost 20 Million Lives in a Year, Modelling Study Estimates – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 

Phase 2a RCT: Vaccine efficacy in adults in a respiratory syncytial virus challenge study.

27 Jun, 2022 | 11:21h | UTC

Vaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge Study -New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Challenge Study Shows Efficacy of RSV Vaccine in Healthy Adults – HealthDay

 

Commentary on Twitter

 

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

27 Jun, 2022 | 11:17h | UTC

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Gastroenterology & Hepatology

Commentary: Chronic Hepatitis B Infections Decreasing in Recent Years – HCP Live

 

Commentary on Twitter

 

Cluster RCT: Effect of automated telephone infectious disease consultations to nonacademic hospitals on 30-day mortality among patients with Staphylococcus aureus bacteremia.

27 Jun, 2022 | 11:03h | UTC

Effect of Automated Telephone Infectious Disease Consultations to Nonacademic Hospitals on 30-Day Mortality Among Patients With Staphylococcus aureus Bacteremia: The SUPPORT Cluster Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 

Systematic Review: Parenteral Vitamin C in patients with severe infection.

24 Jun, 2022 | 11:49h | UTC

Parenteral Vitamin C in Patients with Severe Infection: A Systematic Review – NEJM Evidence

Related:

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit – New England Journal of Medicine

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis – Intensive Care Medicine

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA

 

New COVID drugs face delays as trials grow more difficult.

24 Jun, 2022 | 11:47h | UTC

New COVID drugs face delays as trials grow more difficult – Nature

 

Is shorter always better? The pros and cons of treating Gram-negative bloodstream infections with 7 days of antibiotics.

24 Jun, 2022 | 11:38h | UTC

Is shorter always better? The pros and cons of treating Gram-negative bloodstream infections with 7 days of antibiotics – JAC-Antimicrobial Resistance

 

Perspective | Four areas of health innovation boosted by the pandemic.

24 Jun, 2022 | 11:36h | UTC

Four areas of health innovation boosted by the pandemic – Nature Medicine

 

Commentary on Twitter

 

Cohort Study: COVID-19 trajectories among 57 million adults in England.

24 Jun, 2022 | 11:34h | UTC

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records – The Lancet Digital Health

News Release: Most comprehensive analysis of COVID-19 data reveals previously unattributed deaths – Health Data Research UK

 

Commentary from one of the authors on Twitter (thread – click for more)

 

EULAR/PRES recommendations for vaccination of pediatric patients with autoimmune inflammatory rheumatic diseases.

24 Jun, 2022 | 11:17h | UTC

EULAR/PRES recommendations for vaccination of paediatric patients with autoimmune inflammatory rheumatic diseases: update 2021 – Annals of Rheumatic Diseases

 

Hemorrhagic fever with renal syndrome: literature review, epidemiology, clinical picture and pathogenesis.

24 Jun, 2022 | 11:02h | UTC

Hemorrhagic Fever with Renal Syndrome: Literature Review, Epidemiology, Clinical Picture and Pathogenesis – Infections & Chemotherapy

 

Retrospective Cohort Study: Prevalence and predictors of Pseudomonas aeruginosa among hospitalized patients with diabetic foot infections.

24 Jun, 2022 | 10:43h | UTC

Prevalence and Predictors of Pseudomonas aeruginosa among Hospitalized Patients with Diabetic Foot Infections – Open Forum Infectious Diseases

 

Commentary on Twitter

 

Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.

23 Jun, 2022 | 10:38h | UTC

News Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine

Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

 

Systematic Review: SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19.

23 Jun, 2022 | 10:37h | UTC

SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19 – Cochrane Library

Summary: Are laboratory-made COVID-19-specific monoclonal antibodies effective to prevent COVID-19 in adults? – Cochrane Library

 

Risk factors for SARS-CoV-2 related severe Multisystem Inflammatory Syndrome in Children investigated in a Swedish population-based study.

23 Jun, 2022 | 10:36h | UTC

News Release: Risk factors for severe COVID-19 complication in children investigated in Swedish population-based study – Karolinska Institutet

Original Study: Risk factors for multisystem inflammatory syndrome in children – A population-based cohort study of over 2 million children – The Lancet Regional Health Europe

 

M-A: Incidence and etiology of infant Gram-negative bacteremia and meningitis in children.

23 Jun, 2022 | 10:27h | UTC

Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis – Archives of Disease in Childhood

 

Systematic Review: Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection.

23 Jun, 2022 | 10:09h | UTC

Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection – Cochrane Library

Summary: Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection – Cochrane Library

 

Commentary from the author on Twitter

 

Systematic Review: Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria.

23 Jun, 2022 | 10:07h | UTC

Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

Summary: Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

 

ASA and APSF statement on perioperative testing for the COVID-19 virus.

22 Jun, 2022 | 12:19h | UTC

ASA and APSF Statement on Perioperative Testing for the COVID-19 Virus – American Society of Anesthesiologists

Commentary: ASA, APST Update Perioperative SARS-CoV-2 Testing Recommendations – HealthDay

Related:

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 

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