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Geriatrics

CDC panel moves health workers, nursing home residents to front of COVID vaccine line

2 Dec, 2020 | 07:26h | UTC

CDC panel moves health workers, nursing home residents to front of COVID vaccine line – CIDRAP

See also: Health workers, long-term care facilities should get Covid-19 vaccine first, CDC advisory panel says – STAT

 


Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or greater to that for higher dose benzodiazepines

1 Dec, 2020 | 08:25h | UTC

Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study – BMC Medicine

Commentary: The danger of Z-drugs for dementia patients – University of Exeter

 


Long Covid: Comprehensive health assessment three months after recovery from acute COVID-19 revealed problems in several health domains in a substantial number of patients

27 Nov, 2020 | 08:33h | UTC

Comprehensive health assessment three months after recovery from acute COVID-19 – Clinical Infectious Diseases

 


Phase 2 trial of Oxford COVID-19 vaccine finds it is safe and provokes immune response in young as well as in older adults

20 Nov, 2020 | 08:50h | UTC

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

Commentaries: Covid: Oxford vaccine shows ‘encouraging’ immune response in older adults – BBC AND Age and frailty in COVID-19 vaccine development – The Lancet AND Expert reaction to phase 2 trial safety and immunogenicity data from the Oxford COVID-19 vaccine trial including in healthy older adults – Science Media Centre AND Phase 2 trial of Oxford COVID-19 vaccine in healthy older adults finds it is safe and provokes immune response – The Lancet

 

Commentary on Twitter

 


Older adults with COVID-19 commonly present to the ED with delirium

20 Nov, 2020 | 08:46h | UTC

Delirium in Older Patients With COVID-19 Presenting to the Emergency Department – JAMA Network Open

Commentaries: Delirium could signal Covid-19 infection in older adults, study finds – STAT AND Delirium fairly common in older COVID-19 patients – CIDRAP AND Delirium is first symptom for many elderly COVID-19 patients – UPI

 

Commentary on Twitter

 


CDC Report: 9% readmitted after Covid-19 hospitalization. Risk factors were age ≥65 y, chronic medical conditions, recent hospitalization before Covid-19, and discharge to a skilled nursing facility or with home health care

17 Nov, 2020 | 09:46h | UTC

Characteristics of Hospitalized COVID-19 Patients Discharged and Experiencing Same-Hospital Readmission — United States, March–August 2020 – CDC Morbidity and Mortality Weekly Report

Commentary: 9 percent readmitted after index COVID-19 hospitalization – MedicalXpress AND One in 11 coronavirus patients discharged from a hospital is readmitted within two months, suggesting long-lasting effects of the infection, CDC report warns – Daily Mail

 

Commentary on Twitter

 


Sleep problems in dementia: Despite many drugs being widely prescribed, systematic review finds lack of evidence and no randomized controlled trials to guide decisions about drug treatment

17 Nov, 2020 | 09:29h | UTC

Pharmacotherapies for sleep disturbances in dementia – Cochrane Library

 


Long Covid: 2 months after being hospitalized for Covid-19, many patients persisted symptomatic and did not resume normal activities

13 Nov, 2020 | 09:28h | UTC

Sixty-Day Outcomes Among Patients Hospitalized With COVID-19 – Annals of Internal Medicine

Commentary: Life after COVID hospitalization: Study shows major lasting effects on health, work and more – University of Michigan

 

Commentary on Twitter

 


Long Covid: Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection

13 Nov, 2020 | 09:27h | UTC

Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection – PLOS One

Commentary: Half of recovered COVID-19 patients report lingering fatigue – CIDRAP

 


Older age and frailty are frequently associated with atypical and unspecific COVID-19 presentations, including functional decline, acute mental change, and hypotension

12 Nov, 2020 | 09:22h | UTC

Divergent: age, frailty, and atypical presentations of COVID-19 in hospitalized patients – The Journals of Gerontology

 

Commentary on Twitter

 


Randomized trial: vitamin D, omega-3 fatty acids, or a strength-training exercise program do not improve clinical outcomes in older adults

11 Nov, 2020 | 09:11h | UTC

Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial – JAMA (free for a limited period)

 


[Not published yet – presented at #ACR20] Randomized trial: Methotrexate improves function in people with knee osteoarthritis after 3 months

9 Nov, 2020 | 01:19h | UTC

Methotrexate improves function in people with knee OA after 3 months – American College of Rheumatology

 


[Abstract Only] Large randomized trial fails to show benefit from a multifactorial prevention strategy to prevent falls and fractures in older people

6 Nov, 2020 | 09:48h | UTC

Screening and Intervention to Prevent Falls and Fractures in Older People – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: No reduction in fractures seen in falls prevention programmes prescribed to older people – University of Warwick

Related study: A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries – New England Journal of Medicine

 


[Abstract Only] More than a third of older adults are prescribed potentially inappropriate drugs, study finds

6 Nov, 2020 | 09:42h | UTC

More than a third of older adults are prescribed potentially inappropriate drugs, study finds – Lown Institute

Original study: Potentially Inappropriate Medications Are Associated with Increased Healthcare Utilization and Costs – Journal of the American Geriatrics Society (link to abstract – $ for full-text)

 


Study provides new estimates of breast cancer risks associated with different hormone replacement therapy preparations

30 Oct, 2020 | 01:04h | UTC

Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases – The BMJ

Commentaries: Study provides new estimates of breast cancer risks associated with HRT – University of Oxford AND New estimates of breast cancer risks associated with HRT – The BMJ AND HRT: Breast Ca Risk Tied to Hormone Type, Duration of Tx – Physician’s Weekly

 


Narrative systematic review: Benefits of medication charts provided at transitions of care

25 Oct, 2020 | 23:29h | UTC

Benefits of medication charts provided at transitions of care: a narrative systematic review – BMJ Open

 


Meta-analysis: Evidence-based prevention of Alzheimer’s disease

20 Oct, 2020 | 01:21h | UTC

Evidence-based prevention of Alzheimer’s disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials – Journal of Neurology, Neurosurgery & Psychiatry

Commentaries: Biggest risk factors identified to try and prevent Alzheimer’s disease – BMJ AND Systematic review finds ten lifestyle factors that clearly impact the probability of developing Alzheimer’s disease (AD) – Sharp Brains

 

Commentary on Twitter

 


[Preprint] Multi-organ impairment in low-risk individuals with long COVID

18 Oct, 2020 | 23:18h | UTC

Multi-organ impairment in low-risk individuals with long COVID – medRxiv

Related study (preprint): Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services – medRxiv

 

Commentary on Twitter

 


NIHR dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid)

18 Oct, 2020 | 23:14h | UTC

A dynamic review of the evidence around ongoing Covid19 symptoms (often called Long Covid) – National Institute for Health Research

News Release: Living with COVID: NIHR publishes dynamic themed review into ‘ongoing COVID’

Commentaries: Coronavirus: ‘Long Covid could be four different syndromes’ – BBC AND Long covid could be four different syndromes, review suggests – The BMJ AND ‘Long COVID’ may affect multiple parts of body and mind, doctors say – Reuters

 


Randomized trial: Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women

18 Oct, 2020 | 23:06h | UTC

Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women: multicentre randomised controlled trial – The BMJ

Commentary: For Urinary Incontinence, No Need to Add Biofeedback to Pelvic Floor Exercises – NEJM Journal Watch

 

Commentary on Twitter

 


Randomized trial: Targeting rehabilitation to improve outcomes after total knee arthroplasty in patients at risk of poor outcomes

18 Oct, 2020 | 23:04h | UTC

Targeting rehabilitation to improve outcomes after total knee arthroplasty in patients at risk of poor outcomes: randomised controlled trial – The BMJ

Commentary: Self-Directed Physical Therapy Effective After Total Knee Arthroplasty – NEJM Journal Watch

 

Commentaries on Twitter

 


SCCM International consensus conference on prediction and identification of long-term impairments after critical illness

18 Oct, 2020 | 22:59h | UTC

Society of Critical Care Medicine’s International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness – Critical Care Medicine

Systematic review: Prediction Models for Physical, Cognitive, and Mental Health Impairments After Critical Illness: A Systematic Review and Critical Appraisal – Critical Care Medicine

Source: Grupo UTI Clínica HCFMUSP

 

Commentary on Twitter

 


Study: Polypharmacy (taking > 10 medications) is common in older patients with heart failure

15 Oct, 2020 | 09:03h | UTC

Polypharmacy in Older Adults Hospitalized for Heart Failure – Circulation: Heart Failure

Commentaries: Ten or more medications, often prescribed to older heart failure patients, raises concerns – American Heart Association AND Polypharmacy Common Among Older Heart Failure Patients – Physician’s Weekly

 

Commentary on Twitter

 


Meta-analysis: Association of receipt of palliative care interventions with health care use, quality of life, and symptom burden among adults with chronic noncancer illness

14 Oct, 2020 | 09:18h | UTC

Association of Receipt of Palliative Care Interventions With Health Care Use, Quality of Life, and Symptom Burden Among Adults With Chronic Noncancer Illness: A Systematic Review and Meta-analysis – JAMA

Editorial: Palliative Care for Patients With Noncancer Illnesses

 

Commentary on Twitter

 


‘Long Covid’: Why are some people not recovering?

13 Oct, 2020 | 01:03h | UTC

‘Long Covid’: Why are some people not recovering? – BBC

 


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