Geriatrics
CDC Study: Suspected SARS-CoV-2 reinfections in a skilled nursing facility
28 Feb, 2021 | 21:55h | UTCCommentaries: Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility – HealthDay AND Reinfections could be more likely among those with a mild first case of COVID-19: case study – CTV News
Commentary on Twitter (thread – Click for more)
📌CDC report: Asymptomatic or mildly symptomatic infections don't always produce sufficient immune response to prevent reinfection. Report of nursing facility found 5 people reinfected ~3 months after initial infection. All 5 had more severe symptoms 2nd time around, one death🧵 pic.twitter.com/m9ix9XJolA
— Dr. Ali Nouri (@AliNouriPhD) February 28, 2021
WHO Report: Preparing for Long COVID 2021
26 Feb, 2021 | 08:46h | UTCIn the wake of the pandemic: preparing for Long COVID (2021) – World Health Organization
Commentaries: Long COVID sufferer still has disease’s debilitating symptoms nearly a year after first falling ill – EuroNews AND Debilitating ‘long-COVID’ may have severe health, social impacts: WHO – Reuters
Related: Dr. Fauci says new data suggests ‘long’ Covid symptoms can last up to 9 months – CNBC
RCT: Effect of telephone cognitive behavioral therapy for insomnia in older adults with osteoarthritis pain
25 Feb, 2021 | 08:29h | UTCCommentary: Effective treatment for insomnia delivered in a few short phone calls – University of Washington
Medication review interventions to reduce hospital readmissions in older people
24 Feb, 2021 | 02:14h | UTC
Commentary on Twitter
A medication review in combination with medication reconciliation, patient education, professional education and transitional care is associated with a decreased risk of hospital readmissions. #geriatrics https://t.co/nAeHF82dlm pic.twitter.com/50lEVVeQwn
— JAGS (@AGSJournal) February 16, 2021
State of the Art Review: Vaccines for older adults
23 Feb, 2021 | 01:23h | UTCVaccines for older adults – The BMJ (free for a limited period)
Long Covid: Sequelae in adults at 6 Months after COVID-19 infection
21 Feb, 2021 | 22:13h | UTCSequelae in Adults at 6 Months After COVID-19 Infection – JAMA Network Open
Commentaries: Almost a third of people with ‘mild’ COVID-19 still battle symptoms months later, study finds – CNN AND Nearly One Third of Covid-19 Survivors Have Symptoms, Some Up To 9 Months Later, New Study Finds – Forbes
Commentary on Twitter
Long COVID:
~1/3 of COVID-19 pts had lingering symptoms of a median of 6 mths after infection onset.Among pts whose infections ranged from asymptomatic to severe, 2 problems — fatigue & loss of smell/taste persisted most frequently.https://t.co/xoaWwskPnP
— Christopher Lee (@chriskc_Lee) February 20, 2021
Study: In intensively treated hypertensive patients, a diastolic blood pressure of less than 60 mm Hg was associated with increased risk of cardiovascular events
19 Feb, 2021 | 02:37h | UTCCommentary: Treated Diastolic Blood Pressure: How Low Is Too Low? – NEJM Journal Watch
Commentary on Twitter
Cohort study showed on-treatment diastolic BP <60 was associated with increased risk of adverse outcomes; on-treatment diastolic BP of 70-80 was associated with lowest adverse outcome risk in patients with on-treatment systolic BP <130 mmHg. @MayoClinic https://t.co/0wOfqpMcIH
— JAMA Network Open (@JAMANetworkOpen) February 17, 2021
M-A: Intra-articular saline injection is as effective as corticosteroids, platelet-rich plasma, and hyaluronic acid for hip osteoarthritis pain
19 Feb, 2021 | 02:35h | UTC
Commentary on Twitter
Anyone else buying shares in saline? 👀
Intra-articular saline as effective as corticosteroids, PRP and hyaluronic acid for hip OA pain: a systematic review and network meta-analysis #NoSilverBullet #Paywallhttps://t.co/B6tutNJVDD pic.twitter.com/f75ExkZ2A6
— British Journal of Sports Medicine (@BJSM_BMJ) August 27, 2020
How many people get ‘long COVID’ – and who is most at risk?
19 Feb, 2021 | 02:54h | UTCHow many people get ‘long COVID’ – and who is most at risk? – The Conversation
SR: Integrating palliative care in ambulatory care of noncancer serious chronic illness
19 Feb, 2021 | 02:28h | UTCFull report: Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness
Evidence summary: Integrating Palliative Care in Ambulatory Care of Noncancer Serious Illness
RCT: Levothyroxine does not reduce the risk of developing depressive symptoms in older adults with subclinical hypothyroidism
18 Feb, 2021 | 02:46h | UTCRelated Studies: Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine AND L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial – Annals of Internal Medicine
Guidelines (conflicting viewpoints): BMJ Guideline: Treatment of Subclinical Hypothyroidism AND Society for Endocrinology & British Thyroid Association issue statement against new treatment recommendations for subclinical hypothyroidism
Commentary on Twitter
Ancillary study of the TRUST RCT of levothyroxine therapy finds it does not reduce depression risk among older adults with subclinical hypothyroidism and shouldn't be prescribed for this purpose. #VisualAbstract https://t.co/yu3EChdkm1
— JAMA Network Open (@JAMANetworkOpen) February 10, 2021
M-A: Preventable medication harm across health care settings
18 Feb, 2021 | 02:43h | UTCCommentary: Preventable medication harm across health care settings: a systematic review and meta-analysis – PSNet
RCT: Among patients with knee osteoarthritis, high-intensity strength training was not associated with better outcomes compared with low-intensity strength training or an attention control
17 Feb, 2021 | 01:24h | UTCCommentary: No Benefit from High-Intensity Strength Training for Knee Osteoarthritis – NEJM Journal Watch
Commentary on Twitter
Hot from press: JAMA paper puts question mark on the effectiveness of both low- and high-intensity exercise for knee OA pain. Attention controls had similar improvement. Contextual effects and RTM phenomenon in OA may be powerful! https://t.co/EBrXZcvyXH@OARSInews @JAMA_current pic.twitter.com/880InW1Lag
— Martin Englund (@dr_englund) February 16, 2021
Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee OsteoarthritisThe START Randomized Clinical Trial
👀👀👇👇😳😳https://t.co/W6EQizkiAM pic.twitter.com/RViK36gjHv
— Physio Meets Science (@PhysioMeScience) February 16, 2021
Cohort study: Risk factors associated with transition from acute to chronic low back pain
17 Feb, 2021 | 01:21h | UTC
Commentary on Twitter
Risk Factors Associated With Transition From Acute to Chronic Low Back Pain in US Patients Seeking Primary Care
👀👀👇👇https://t.co/DzpfvWMzIV pic.twitter.com/qzvoJL2Mxf
— Physio Meets Science (@PhysioMeScience) February 16, 2021
SR: Interventions for improving outcomes in patients with multimorbidity in primary care and community settings
17 Feb, 2021 | 01:11h | UTCSummary: Improving outcomes for people with multiple chronic conditions – Cochrane Library
Review: Diagnosis and treatment of hip and knee osteoarthritis
16 Feb, 2021 | 02:05h | UTCDiagnosis and Treatment of Hip and Knee Osteoarthritis: A Review – JAMA (free or a limited period)
Effectiveness of telerehabilitation in physical therapy: A rapid overview
16 Feb, 2021 | 01:53h | UTCEffectiveness of telerehabilitation in physical therapy: A rapid overview – Physical Therapy
M-A: No link between blood pressure drugs and falls
12 Feb, 2021 | 02:05h | UTCNo link between blood pressure drugs and falls, finds study – University of Oxford
Original study: Association between antihypertensive treatment and adverse events: systematic review and meta-analysis – The BMJ
Commentary on Twitter (thread – click for more)
Can #bloodpressure treatment be harmful? Our new meta-analysis suggests it is NOT linked to #falls or #fractures but may increase the risk of syncope & acute kidney injury https://t.co/H5LlsFVBXJ – see thread @RichardJMcManus @Richard_D_Riley @ebhcmedstats @JulietU_S @drandyclegg pic.twitter.com/UtWjE1BzMW
— James Sheppard (@jamessheppard48) February 10, 2021
SR: Plasma and cerebrospinal fluid ABeta42 for the differential diagnosis of Alzheimer’s disease dementia
12 Feb, 2021 | 01:53h | UTC
RCT: The effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults
11 Feb, 2021 | 01:58h | UTCThe effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)
Commentary on Twitter
Daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial https://t.co/sT81S8JfNs
No effect of protein supplementation in older persons, but lifting is good!
— Stuart Phillips (@mackinprof) February 10, 2021
WHO experts recommend AstraZeneca COVID vaccine across all ages and countries
11 Feb, 2021 | 02:20h | UTCCommentaries: WHO Experts Recommend AstraZeneca COVID Vaccine Across All Ages & Countries – Signal For Start Of Global COVAX Vaccine Rollout – Health Policy Watch AND WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages – The Guardian AND Covid: WHO backs Oxford vaccine ‘even if variants present’ – BBC AND Expert reaction to WHO recommending use of the Oxford/AstraZeneca COVID-19 vaccine, including in over 65s – Science Media Centre AND Up Against Mutants, WHO Says AstraZeneca Vaccine Is Still A Good Bet – NPR
Cohort study: Low risk of progression to diabetes among older adults with “prediabetes”
9 Feb, 2021 | 01:09h | UTCRisk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine (free for a limited period)
Commentaries: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health AND Prediabetes—A Risk Factor Twice Removed – JAMA Internal Medicine (free for a limited period) AND How many pre-diabetics go on to develop diabetes? – MedicalResearch.com
Author Interview: Risk of Progression to Diabetes Among Older Adults With Prediabetes
Related: The war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science
Canadians Win Again – Syncope Score Systematic Review
9 Feb, 2021 | 01:03h | UTCCanadians Win Again – Syncope Score Systematic Review – Journal Feed
See calculator: Canadian Syncope Risk Score – MdCalc
Review: Dysphagia in older adults
5 Feb, 2021 | 01:22h | UTCDysphagia in Older Adults – Mayo Clinic Proceedings
The AstraZeneca vaccine and over-65s: we may not have all the data yet, but limiting access could be counterproductive
3 Feb, 2021 | 01:46h | UTC