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Geriatrics

M-A: Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis – although Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be most effective treatments, topical diclofenac 70-81 mg/day is safer and should be considered as first line treatment.

17 Oct, 2021 | 21:14h | UTC

Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis – The BMJ

News release: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital

Commentary: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News

 

Commentary on Twitter

 


WHO provides guidance to address the shortage of quality palliative care services.

14 Oct, 2021 | 09:59h | UTC

News release: WHO takes steps to address glaring shortage of quality palliative care services – World Health Organization

See Guidance:

Assessing the development of palliative care worldwide: a set of actionable indicators – World Health Organization

Quality health services and palliative care: practical approaches and resources to support policy, strategy and practice – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.

13 Oct, 2021 | 01:36h | UTC

USPSTF Draft Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease – U.S. Preventive Services Task Force

Commentaries:

Advice shifting on aspirin use for preventing heart attacks – Associated Press

Taking aspirin to prevent heart attack may cause more harm than good, task force says – NPR

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

 

Commentary on Twitter

 


RCT: Laser treatment not better than sham treatment on symptom severity in women with postmenopausal vaginal symptoms.

13 Oct, 2021 | 01:30h | UTC

Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial – JAMA (free for a limited period)

News release: This laser is supposed to rejuvenate vaginal tissue. But scientists say it’s no better than a placebo – University of New South Wales

Editorial: Time for a “Pause” on the Use of Vaginal Laser (free for a limited period)

Author Interview: Effect of Carbon Dioxide Laser vs Sham Therapy on Women With Postmenopausal Vaginal Symptoms

Commentary: Vagina lasering for postmenopausal women ‘may be placebo’ – The Guardian

 

Commentary on Twitter

 


Survey finds misperceptions associated with palliative care are widespread – stigma may be perpetuated by those who falsely believe they understand its meaning.

11 Oct, 2021 | 23:54h | UTC

Public knowledge and attitudes concerning palliative care – BMJ Supportive & Palliative Care

 

Commentary on Twitter

 


U.S. Data: Drug-resistant Infections led to $1.9 billion in health care costs, more than 10,000 deaths among older adults in one year.

8 Oct, 2021 | 10:11h | UTC

News release: Drug-resistant Infections Led to $1.9 Billion in Health Care Costs, More Than 10,000 Deaths Among Older Adults in One Year – Infectious Diseases Society of America

Original study: Mortality, Length of Stay, and Healthcare Costs Associated With Multidrug-Resistant Bacterial Infections Among Elderly Hospitalized Patients in the United States – Clinical Infectious Diseases

Commentaries:

Urgent, Comprehensive Federal Action Needed To Stem Mortality and Medicare Costs Associated With Antimicrobial Resistance – Clinical Infectious Diseases

Study highlights impact of antibiotic resistance on older Americans – CIDRAP

 


Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.

8 Oct, 2021 | 10:07h | UTC

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

 


Choosing Wisely: Seven things physicians and residents/patients should question in long term care.

7 Oct, 2021 | 10:31h | UTC

Seven Things Physicians and Residents/Patients Should Question – Canadian Society for Long Term Care Medicine

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


SILENCE Randomized Trial: In patients at the end of life, prophylactic subcutaneous scopolamine butylbromide reduces the occurrence of the death rattle (noisy breathing caused by mucus in the upper respiratory tract).

6 Oct, 2021 | 09:54h | UTC

Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle in Patients at the End of LifeThe SILENCE Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide – JAMA (free for a limited period)

Author interview: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle – JAMA

 

Commentary on Twitter

 


Series from the Lancet journals: Hematological malignancies in older people.

6 Oct, 2021 | 08:47h | UTC

Homepage: Haematological malignancies in older people – The Lancet Haematology

Commentary: Living longer and better with haematological malignancies: a promise for older adults too? (free registration required)

A comprehensive approach to therapy of haematological malignancies in older patients (free registration required)

Frailty assessment in the care of older people with haematological malignancies

Haematopoietic stem-cell transplantation in older adults: geriatric assessment, donor considerations, and optimisation of care (free registration required)

Palliative care of patients with haematological malignancies: strategies to overcome difficulties via integrated care

Implementation of geriatric haematology programmes for the treatment of older people with haematological malignancies in low-resource settings

 


Review: Optimizing care for critically ill older adults.

5 Oct, 2021 | 08:51h | UTC

Optimizing care for critically ill older adults – Canadian Medical Association Journal

 


Systematic Review: Is exercise an effective therapy to treat long-lasting low back pain?

3 Oct, 2021 | 22:32h | UTC

Summary: Is exercise an effective therapy to treat long-lasting low back pain? – Cochrane Library

Original Study: Exercise therapy for chronic low back pain – Cochrane Library

 

Commentary on Twitter

 


Review: COVID-19 in older adults.

1 Oct, 2021 | 10:27h | UTC

COVID-19 in older adults – Cleveland Clinic Journal of Medicine

 


Guideline Synopsis: The Non-Surgical Management of Hip and Knee Osteoarthritis.

1 Oct, 2021 | 10:00h | UTC

Synopsis of the 2020 US Department of Veterans Affairs/US Department of Defense Clinical Practice Guideline: The Non-Surgical Management of Hip and Knee Osteoarthritis – Mayo Clinic Proceedings

 


AUA Guidelines: Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia.

1 Oct, 2021 | 09:58h | UTC

Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA GUIDELINE – The Journal of Urology

PART I—Initial Work-up and Medical Management

PART II—Surgical Evaluation and Treatment

 


NCCN Guideline: Older Adult Oncology

30 Sep, 2021 | 09:59h | UTC

NCCN Guidelines® Insights: Older Adult Oncology, Version 1.2021 – Journal of the National Comprehensive Cancer Network

 


Never Waste a Pandemic: Strategies to Increase Advance Care Planning Now.

29 Sep, 2021 | 10:22h | UTC

Never Waste a Pandemic: Strategies to Increase Advance Care Planning Now – Mayo Clinic Proceedings

 


Guideline for Perioperative Care for People Living with Frailty Undergoing Elective and Emergency Surgery.

29 Sep, 2021 | 10:10h | UTC

News release and infographic: Perioperative Care of People Living with Frailty – Centre for Perioperative Care

Guideline: Perioperative Care for People Living with Frailty Undergoing Elective and Emergency Surgery – British Geriatrics Society

 

Commentary on Twitter

 


Review: Sensory Dysfunction in Old Age.

29 Sep, 2021 | 09:57h | UTC

Sensory Dysfunction in Old Age – Deutsches Ärzteblatt International

 


Systematic review: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities?

28 Sep, 2021 | 09:47h | UTC

Commentary: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities? – Cochrane Library

Original study: Non‐pharmacological measures implemented in the setting of long‐term care facilities to prevent SARS‐CoV‐2 infections and their consequences: a rapid review – Cochrane Library

 


RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.

28 Sep, 2021 | 09:06h | UTC

Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)

Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)

 

Commentary on Twitter

 


Phenotypes and subphenotypes of delirium: a review of current categorizations and suggestions for progression.

23 Sep, 2021 | 09:54h | UTC

Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression – Critical Care

 


Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.

22 Sep, 2021 | 10:02h | UTC

Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial – The BMJ

 


Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond.

22 Sep, 2021 | 09:57h | UTC

Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond – Critical Care Medicine

 


AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.

21 Sep, 2021 | 09:03h | UTC

News release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons

Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons

Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline

 


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