Geriatrics
The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly.
24 Jan, 2022 | 08:24h | UTCRelated:
ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.
Review: Changing paradigms in the management of acute uncomplicated diverticulitis.
Review: Elective surgical management of diverticulitis
State of the Art Review | Management of colonic diverticulitis
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
Systematic review: Management of colonic diverticulitis
WSES Guidelines for the Management of Acute Colonic Diverticulitis
ASCRS Guidelines for the Treatment of Left-Sided Colonic Diverticulitis
Review: Postdischarge Evaluation for Individuals Hospitalized with COVID-19.
21 Jan, 2022 | 10:08h | UTCPostdischarge Evaluation for Individuals Hospitalized with COVID-19 – Southern Medical Journal
RCT: Metal pins no better than traditional plaster cast for a broken wrist.
21 Jan, 2022 | 09:51h | UTCNews Release: Metal pins no better than traditional plaster cast for a broken wrist – BMJ
Original Study: Surgical fixation with K-wires versus casting in adults with fracture of distal radius: DRAFFT2 multicentre randomised clinical trial – The BMJ
Commentary: Wrist fractures: study compares casting to surgical fixation – MedicalResearch.com
Commentary on Twitter
Fascinating to read the results of #DRAFFT2 in the BMJ. Lots to think about: No difference in wrist function at 12 months but higher reoperation rate for loss of position in cast-only group (13% v 0.4%) #orthotwitter https://t.co/QJO43XBdB6 pic.twitter.com/IMCpcsoiSh
— Tom Lewis (@thomasllewis) January 20, 2022
Systematic Review: In people with Alzheimer’s disease and vascular dementia with agitation and psychosis, atypical antipsychotics probably reduce agitation slightly (moderate‐certainty evidence) but probably have a negligible effect on psychosis or risk of any adverse event.
21 Jan, 2022 | 09:50h | UTC
Cluster Randomized Trial: A multifactorial falls prevention program in UK care homes reduced fall rates among older people and was cost effective.
21 Jan, 2022 | 09:21h | UTCNews Release: Falls in care homes can be significantly reduced with intervention, says new study – University of Nottingham
Commentary on Twitter
NEW RESEARCH: A falls prevention programme for older people in care homes, co-designed with care home staff & residents, that involved awareness raising, education, screening, decision & implementation support was associated with a reduction in falls rate https://t.co/wupI0LeAxj
— The BMJ (@bmj_latest) December 11, 2021
Study shows that the retinal age gap might be a potential biomarker of aging linked to increased mortality risk.
20 Jan, 2022 | 09:04h | UTCRetinal age gap as a predictive biomarker for mortality risk – British Journal of Ophthalmology (link to abstract – $ for full-text)
News Release: Difference between retina’s biological age and person’s real age linked to heightened death risk – BMJ
Commentary on Twitter
Difference between retina’s biological age and person’s real age linked to heightened death risk finds @BMJ_Ophth study https://t.co/TNveo5E77D
— BMJ (@bmj_company) January 19, 2022
Cohort Study: Factors associated with 10-year declines in physical health and function among women during midlife.
19 Jan, 2022 | 08:29h | UTCCommentary: Four Factors in Midlife Predict a Healthy Old Age for Women – HealthDay
Perspective | Post-acute neurological consequences of COVID-19: an unequal burden – “COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity”.
18 Jan, 2022 | 09:44h | UTCPost-acute neurological consequences of COVID-19: an unequal burden – Nature Medicine
Global, regional, and national burdens of hip osteoarthritis from 1990 to 2019: estimates from the 2019 Global Burden of Disease Study.
18 Jan, 2022 | 09:27h | UTC
RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.
16 Jan, 2022 | 23:13h | UTCThe D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Related:
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Research: Circulating vitamin D concentration and risk of seven cancers
Research: Vitamin D and risk of total and site specific cancers
RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.
16 Jan, 2022 | 23:11h | UTCNews Release: Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer – University of Eastern Finland
Related:
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Research: Circulating vitamin D concentration and risk of seven cancers
Research: Vitamin D and risk of total and site specific cancers
Cluster randomized trial: no added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis.
16 Jan, 2022 | 22:59h | UTC
Perspective: Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age.
16 Jan, 2022 | 22:53h | UTCCommentaries:
Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’ – Florida Atlantic University
Preventive Aspirin Should Be Based on Benefit, Not Age – HealthDay
Analysis: Sarcopenia: early prevention or overdiagnosis?
16 Jan, 2022 | 22:48h | UTCSarcopenia: early prevention or overdiagnosis? – The BMJ
Related: Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary. (several articles on the subject)
Commentary from the author on Twitter
We have a new diagnosis! 2 billion people may turn into patients with sarcopenia. Despite no evidence to justify why we should diagnose elderly people. My latest article in @bmj_latest with @drjohnbrodersen and JBülow. #overdiagnosis #sarcopenia #EBM https://t.co/mNFxmuz4U1
— Christoffer Bjerre Haase (@BjerreHaase) January 13, 2022
Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.
12 Jan, 2022 | 09:09h | UTCCommentaries:
Pfizer antiviral pills may be risky with other medications – NBC News
See also: What’s New in the Guidelines – NIH COVID-19 Treatment Guidelines
Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.
11 Jan, 2022 | 02:38h | UTCNews Release: Global dementia cases set to triple by 2050 unless countries address risk factors – The Lancet
Commentaries:
Forecasting the prevalence of dementia – The Lancet Public Health
Dementia cases expected to almost triple across the world by 2050 – BBC
Number of adults with dementia to exceed 150m by 2050, study finds – The Guardian
Commentary on Twitter (thread – click for more)
🆕✨First #GBDstudy forecasts global #dementia cases set to triple by 2050 (up from 57m in 2019 to expected 153m people) unless countries address risk factors: #smoking, #obesity, #HighBloodSugar, & low #education🧵👇
Published in @TheLancet @TheLancetPHhttps://t.co/GccTPRroEV
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) January 7, 2022
AAN Guideline: Oral and topical treatment of painful diabetic polyneuropathy.
8 Jan, 2022 | 23:18h | UTCNews Release: AAN Issues Guideline for Treatment of Painful Diabetic Neuropathy – American Academy of Neurology
RCT: In older patients undergoing hip fracture surgery, regional anesthesia did not reduce the incidence of postoperative delirium compared to general anesthesia.
8 Jan, 2022 | 23:09h | UTCEffect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial – JAMA (link to abstract – $ for full-text)
Commentary: China-wide study will boost understanding of fatal surgical complication – University of Birmingham
Related:
RCT: Spinal Anesthesia not Superior to General Anesthesia for Hip Surgery in Older Adults.
In a large retrospective cohort study of patients with atrial fibrillation 65 years or older, treatment with rivaroxaban compared with apixaban was associated with increased risk of major ischemic or hemorrhagic events.
8 Jan, 2022 | 22:37h | UTCCommentary: Apixaban Appears Safer, More Effective Than Rivaroxaban in Medicare Study – TCTMD
Related:
Retrospective cohort study: In patients with venous thromboembolism (VTE), treatment with apixaban was associated with lower rates for recurrent VTE and bleeding compared to rivaroxaban.
8 Jan, 2022 | 22:36h | UTCCommentaries:
Apixaban shows superior effectiveness, safety compared to rivaroxaban – ACP Internist
Recurrent VTE and Bleeding With Apixaban vs. Rivaroxaban – American College of Cardiology
Prevention of Chemotherapy-induced nausea and vomiting in the older patient: optimizing outcomes.
17 Dec, 2021 | 08:32h | UTCPrevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes – Drugs & Aging (if the link is paywalled, try this one)
Management of Hip Fractures in Older Adults: Evidence-Based Clinical Practice Guideline.
16 Dec, 2021 | 09:42h | UTCSummary: Management of Hip Fractures in Older Adults – American Academy of Orthopaedic Surgeons
News Release: AAOS Updates Clinical Practice Guideline for Management of Hip Fractures in Older Adults
Expert consensus and practical guidance: A global perspective on improving patient care in uncomplicated urinary tract infection.
15 Dec, 2021 | 08:33h | UTC
Proposed subtypes of long-Covid and their respective potential therapies.
14 Dec, 2021 | 09:49h | UTCRelated:
EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.
Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.
Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Review: Neuropsychiatric assessment and management of the ICU survivor.
10 Dec, 2021 | 10:01h | UTC