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Systematic Reviews & Meta-analysis

Systematic Review: Antibiotics for uncomplicated diverticulitis.

27 Jun, 2022 | 11:56h | UTC

Antibiotics for uncomplicated diverticulitis – Cochrane Library

Summary: Antibiotics for uncomplicated diverticulitis – Cochrane Library

Related:

Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)

The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly – World Journal of Emergency Surgery

Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

Elective surgical management of diverticulitis – Current Problems in Surgery

Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality

2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting – World Journal of Emergency Surgery

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis – Diseases of the Colon & Rectum

 

Commentary on Twitter

 


M-A: The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults.

27 Jun, 2022 | 11:42h | UTC

The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis – Age and Ageing

 


Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study.

27 Jun, 2022 | 11:29h | UTC

Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study – The Lancet Digital Health

 

Commentary on Twitter

 


Systematic Review: Short‐acting inhaled bronchodilators for cystic fibrosis.

27 Jun, 2022 | 11:15h | UTC

Short‐acting inhaled bronchodilators for cystic fibrosis – Cochrane Library

Summary: Short-acting inhaled bronchodilators for cystic fibrosis – Cochrane Library

 


Systematic Review: Locally recurrent rectal cancer according to a standardized MRI classification system.

27 Jun, 2022 | 11:07h | UTC

Locally Recurrent Rectal Cancer According to a Standardized MRI Classification System: A Systematic Review of the Literature – Journal of Clinical Medicine

 


M-A: Safety and efficacy of SSRIs in improving poststroke recovery.

27 Jun, 2022 | 10:58h | UTC

Safety and Efficacy of SSRIs in Improving Poststroke Recovery: A Systematic Review and Meta‐Analysis – Journal of the American Heart Association

 


M-A: Hypothermic vs. normothermic temperature control after cardiac arrest.

24 Jun, 2022 | 11:51h | UTC

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest – NEJM Evidence

Related:

ERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis – Critical Care

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine

Targeted Temperature Management for Cardiac Arrest Due to Non-shockable Rhythm: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Frontiers in Medicine

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine

 


Systematic Review: Parenteral Vitamin C in patients with severe infection.

24 Jun, 2022 | 11:49h | UTC

Parenteral Vitamin C in Patients with Severe Infection: A Systematic Review – NEJM Evidence

Related:

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit – New England Journal of Medicine

Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis – Intensive Care Medicine

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA

 


M-A: Benefits and harms of interventions with surgery compared to interventions without surgery for musculoskeletal conditions.

24 Jun, 2022 | 11:04h | UTC

Benefits and Harms of Interventions With Surgery Compared to Interventions Without Surgery for Musculoskeletal Conditions: A Systematic Review With Meta-analysis – Journal of Orthopaedic & Sports Physical Therapy

 


Cataract surgery: both eyes on the same day or on different days?

24 Jun, 2022 | 10:55h | UTC

Cataract surgery: both eyes on the same day or on different days? – Evidently Cochrane

Original Study: Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts – Cochrane Library

 


Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.

23 Jun, 2022 | 10:38h | UTC

News Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine

Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

 


Systematic Review: SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19.

23 Jun, 2022 | 10:37h | UTC

SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19 – Cochrane Library

Summary: Are laboratory-made COVID-19-specific monoclonal antibodies effective to prevent COVID-19 in adults? – Cochrane Library

 


M-A: Incidence and etiology of infant Gram-negative bacteremia and meningitis in children.

23 Jun, 2022 | 10:27h | UTC

Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis – Archives of Disease in Childhood

 


M-A: Early versus delayed complete revascularization in patients presenting with ST-segment elevation myocardial infarction and multivessel disease.

23 Jun, 2022 | 10:11h | UTC

Early versus delayed complete revascularisation in patients presenting with ST-segment elevation myocardial infarction and multivessel disease: a systematic review and meta-analysis of randomised controlled trials – openheart

 


M-A: Intravenous iron vs. oral iron vs. no iron with or without erythropoiesis‐ stimulating agents for cancer patients with anemia.

23 Jun, 2022 | 10:10h | UTC

Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer patients with anaemia: a systematic review and network meta‐analysis – Cochrane Library

Summary: Which combinations of medicines are best for the prevention and treatment of anaemia in people with cancer? – Cochrane Library

 


Systematic Review: Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection.

23 Jun, 2022 | 10:09h | UTC

Interventions to improve water, sanitation, and hygiene for preventing soil‐transmitted helminth infection – Cochrane Library

Summary: Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection – Cochrane Library

 

Commentary from the author on Twitter

 


M-A: Effectiveness of pharmacological-based interventions, including education and prescribing strategies, to reduce subacute pain after total hip or knee arthroplasty.

23 Jun, 2022 | 10:04h | UTC

Effectiveness of Pharmacological-Based Interventions, Including Education and Prescribing Strategies, to Reduce Subacute Pain After Total Hip or Knee Arthroplasty: A Systematic Review of Randomized Controlled Trials – Pain Medicine

Commentary: Multimodal Analgesia and Education Reduces Postoperative Arthroplasty Pain, Opioid Consumption – Rheumatology Advisor

 

Commentary on Twitter

 


Systematic Review: Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria.

23 Jun, 2022 | 10:07h | UTC

Pyronaridine‐artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

Summary: Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

 


Induction chemotherapy in nasopharyngeal carcinoma- A systematic review of phase III clinical trials.

23 Jun, 2022 | 09:54h | UTC

Induction chemotherapy in nasopharyngeal carcinoma- A systematic review of phase III clinical trials – Cancer Treatment and Research Communications

 


Systematic Review: Music therapy for people with substance use disorders.

22 Jun, 2022 | 11:02h | UTC

Music therapy for people with substance use disorders – Cochrane Library

Summary: Music therapy for people with substance use disorder – Cochrane Library

 


M-A: Opioid versus opioid-free analgesia after surgical discharge.

21 Jun, 2022 | 11:08h | UTC

Opioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis of randomised trials – The Lancet (link to abstract – $ for full-text)

News Release: Taking opioids at home after surgery: More harms than benefits – McGill University Health Center

 


M-A: Comparison of bifurcation techniques for percutaneous coronary intervention.

21 Jun, 2022 | 10:50h | UTC

Systematic Review and Network Meta‐Analysis Comparing Bifurcation Techniques for Percutaneous Coronary Intervention – Journal of the American Heart Association

 


Cohort Study: Association of obsessive-compulsive disorder and obsessive-compulsive symptoms with substance misuse.

21 Jun, 2022 | 10:42h | UTC

Association of Obsessive-Compulsive Disorder and Obsessive-Compulsive Symptoms With Substance Misuse in 2 Longitudinal Cohorts in Sweden – JAMA Network Open

 

Commentary on Twitter

 


M-A: Benefits and risks of rapid initiation of antiretroviral therapy in patients with HIV.

21 Jun, 2022 | 10:41h | UTC

Benefits and Risks of Rapid Initiation of Antiretroviral Therapy: A Systematic Review and Meta-Analysis – Frontiers in Pharmacology

 


M-A: Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for diagnosing periprosthetic joint infections.

21 Jun, 2022 | 10:38h | UTC

A Systematic Review and Meta-Analysis on the Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for Diagnosing Periprosthetic Joint Infections – Frontiers in Surgery

 


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