Systematic Reviews & Meta-Analysis
M-A: Treatment with convalescent plasma is not associated with better outcomes in patients with Covid-19
28 Feb, 2021 | 21:51h | UTCEditorial: Emerging Lessons From COVID-19 for the US Clinical Research Enterprise
Commentary on Twitter
Just out: Our meta-analysis in @JAMA_current
"Among patients with COVID-19, treatment with convalescent plasma compared with control was not associated with improved survival or other positive clinical outcomes"https://t.co/tRqpd9v67m
— Lars G. Hemkens (@LGHemkens) February 26, 2021
M-A: Risk predictors of progression to severe disease during the febrile phase of dengue
28 Feb, 2021 | 20:57h | UTC
Cognitive behavioral therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
28 Feb, 2021 | 20:50h | UTC
Systematic Review: Cardiovascular Effects of Medical Marijuana
28 Feb, 2021 | 20:48h | UTCCardiovascular Effects of Medical Marijuana: A Systematic Review – The American Journal of Medicine
M-A: Adjuvant corticosteroids are effective in lowering the risk of kidney scarring in children with acute pyelonephritis
28 Feb, 2021 | 20:38h | UTCAdjuvant corticosteroids for prevention of kidney scarring in children with acute pyelonephritis: a systematic review and meta-analysis – Archives of Disease in Childhood (link to abstract – $ for full-text)
Decreasing patient-reported burden of treatment: A systematic review of quantitative interventional studies
26 Feb, 2021 | 08:21h | UTC
Systematic Review: Insufficient evidence to decide whether surgical intervention is beneficial or harmful for the early management of Bell’s palsy
26 Feb, 2021 | 08:20h | UTCSurgical interventions for the early management of Bell’s palsy – Cochrane Library
Summary: Surgical operation for Bell’s palsy (idiopathic facial paralysis) – Cochrane Library
SR: Metformin has modest efficacy for children with obesity
24 Feb, 2021 | 02:08h | UTCEfficacy and Safety of Metformin for Obesity: A Systematic Review – Pediatrics (link to abstract – $ for full-text)
Commentary: Metformin Underwhelms in Pediatric Obesity – Physician’s Weekly
M-A: Blood pressure effects of sodium reduction
23 Feb, 2021 | 01:28h | UTCCommentaries: The Lower the Sodium, the Better for BP: Updated Meta-analysis – TCTMD AND AHA News: Lower Your Sodium, and Blood Pressure Will Follow – HealthDay
M-A: The diagnostic accuracy of noninvasive methods to measure the intracranial pressure
23 Feb, 2021 | 01:14h | UTC
SR: Multisystem inflammatory syndrome in children related to COVID-19
21 Feb, 2021 | 22:11h | UTC
Commentary on Twitter (thread – click for more)
Very proud to present our systematic review on the hyperinflammatory syndrome associated with SARS-CoV-2 in children #PIMS_TS #MISC, as published today in @EurJPediatrics.
We analyzed and summarized over 950 cases from more than 60 records. https://t.co/jO3te1KUIE
(1/n) pic.twitter.com/6BwEw7qFzi
— Levi Hoste (@LeviHoste) February 18, 2021
Meta-analysis: Effect of food variety on intake of a meal
21 Feb, 2021 | 21:33h | UTC
M-A: Intra-articular saline injection is as effective as corticosteroids, platelet-rich plasma, and hyaluronic acid for hip osteoarthritis pain
19 Feb, 2021 | 02:35h | UTC
Commentary on Twitter
Anyone else buying shares in saline? 👀
Intra-articular saline as effective as corticosteroids, PRP and hyaluronic acid for hip OA pain: a systematic review and network meta-analysis #NoSilverBullet #Paywallhttps://t.co/B6tutNJVDD pic.twitter.com/f75ExkZ2A6
— British Journal of Sports Medicine (@BJSM_BMJ) August 27, 2020
SR: Integrating palliative care in ambulatory care of noncancer serious chronic illness
19 Feb, 2021 | 02:28h | UTCFull report: Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness
Evidence summary: Integrating Palliative Care in Ambulatory Care of Noncancer Serious Illness
Meta-analysis: Sustained lung inflations during neonatal resuscitation at birth
19 Feb, 2021 | 02:21h | UTCSustained Lung Inflations During Neonatal Resuscitation at Birth: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentaries on Twitter
#Metaanalysis by @KapadiaNeo & @Ilcor_org colleagues finds Sustained lung inflation is a potential harmful intervention in babies, particularly in extreme preterm infants who are at increased risk of death@AAPJournals @EBNEO #NeoEBM @wyllie_jonathan https://t.co/rsDYtDRgm0 pic.twitter.com/fO6mu4ICil
— Abdul Razak, MD, FRCPCH (@DrAbdulRazak_MD) December 23, 2020
If your center is still using sustained lung inflations this systematic review should give you reason to pause. #neoEBM #Meded #MedTwitter https://t.co/WCHCdHzyGX pic.twitter.com/53lOMIFQas
— Michael Narvey (@NICU_Musings) January 8, 2021
M-A: Not enough evidence there are individual differences in response to antidepressants
19 Feb, 2021 | 02:15h | UTCIndividual Differences in Response to Antidepressants: A Meta-analysis of Placebo-Controlled Randomized Clinical Trials – JAMA Psychiatry (free for a limited period)
Editorial: New Directions in Research on Heterogeneity of Treatment Effects for Major Depression (free for a limited period)
Commentary: Antidepressants for MDD: Time to Rethink Personalized Therapy? – Physician’s Weekly
Related studies: What are the chances for personalised treatment with antidepressants? Detection of patient-by-treatment interaction with a variance ratio meta-analysis – BMJ Open AND Individual response to antidepressants for depression in adults-a meta-analysis and simulation study – PLOS One
Commentary on Twitter (thread – click for more)
1/ Treatment effect heterogeneity in antidepressant tx – a retracted paper by Maslej et al. was now re-published, with a complete reversal of the main-findings – no difference in variability in tx outcome bw antidepressant and placebo. https://t.co/ME5qawCQlL https://t.co/IgegV5kZpT
— Pfluft (@PloederlM) February 18, 2021
M-A: Risk factors for suicide in prisons
19 Feb, 2021 | 02:10h | UTC
Commentary on Twitter (thread – click for more)
New paper! Meta-analysis of risk factors for completed suicide in prison. Included data on >35,000 suicides, 77 studies from 27 countries. Some potentially important findings, esp. differences with risk factors in general population. #OA @TheLancetPH: https://t.co/G26576gOrH 1/ pic.twitter.com/gB7efLHkqK
— Seena Fazel (@seenafazel) February 10, 2021
M-A: Preventable medication harm across health care settings
18 Feb, 2021 | 02:43h | UTCCommentary: Preventable medication harm across health care settings: a systematic review and meta-analysis – PSNet
Incidence rate and clinical impacts of arrhythmia following COVID-19: a systematic review and meta-analysis of 17,435 patients
17 Feb, 2021 | 01:31h | UTC
M-A: Role of diet in colorectal cancer incidence
17 Feb, 2021 | 01:12h | UTC
SR: Interventions for improving outcomes in patients with multimorbidity in primary care and community settings
17 Feb, 2021 | 01:11h | UTCSummary: Improving outcomes for people with multiple chronic conditions – Cochrane Library
SR: Fresh versus frozen embryo transfers in assisted reproduction
17 Feb, 2021 | 01:10h | UTCFresh versus frozen embryo transfers in assisted reproduction – Cochrane Library
Summary: Fresh versus frozen embryo transfers for assisted reproduction – Cochrane Library
Commentary on Twitter
There is probably little or no difference in cumulative live birth rate between freeze all strategy and conventional #IVF #ICSI. Freeze all strategy may reduce the risk of OHSS compared to conventional IVF @CochraneCGF #blogshot https://t.co/d8IZzo4U3f pic.twitter.com/rfwrhI3pEn
— The Cochrane Library (@CochraneLibrary) February 15, 2021
M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome
16 Feb, 2021 | 02:01h | UTC
Commentary on Twitter
Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis "The low-FODMAP diet reduces GI symptoms and improves quality of life in IBS subjects as compared to control diets"https://t.co/tTeRjKOV1O pic.twitter.com/raLdnlDQCJ
— Lukas Schwingshackl (@LSchwingshackl) February 15, 2021
M-A: Intake of dietary fats and fatty acids and the incidence of type 2 diabetes
16 Feb, 2021 | 01:59h | UTC
Systematic review: Urgent‐start peritoneal dialysis vs. hemodialysis for people with chronic kidney disease
15 Feb, 2021 | 00:46h | UTC