Systematic Reviews & Meta-analysis
Degree of Myopia and Glaucoma Risk: A Dose-Response Meta-Analysis.
22 Oct, 2021 | 10:17h | UTC
Systematic Review: anti-interleukin-13 or anti-interleukin-4 agents may be appropriate for adults with moderate-to-severe uncontrolled asthma who have not responded to other treatments.
20 Oct, 2021 | 10:19h | UTC
Commentary on Twitter (thread – click for more)
Lead author David Evans said “Approximately five to ten percent of people with asthma experience symptoms that are severe or difficult-to-treat… [1/3] pic.twitter.com/Nw606oSrX0
— CochraneAirways (@CochraneAirways) October 19, 2021
Systematic Review: Colchicine for the treatment of COVID‐19 – not beneficial for hospitalized patients; inconclusive evidence for the treatment of non-hospitalized patients, “probably slightly reduces the need for hospitalization or death within 28 days compared to placebo”.
19 Oct, 2021 | 10:13h | UTCColchicine for the treatment of COVID‐19 – Cochrane Library
Related:
Commentary on Twitter
JUST PUBLISHED – Is #colchicine (often used to treat #gout) an effective treatment for people with #COVID19? ➡️ https://t.co/IF1enksFpn New @CochraneHaem systematic review includes evidence from 4 RCTS with 11,525 hospitalised & 4488 non‐hospitalised people.
— The Cochrane Library (@CochraneLibrary) October 18, 2021
Systematic Review: Calcium channel blockers versus other classes of drugs for hypertension – “there is moderate certainty evidence that diuretics reduce major cardiovascular events and congestive heart failure more than CCBs”.
19 Oct, 2021 | 08:56h | UTCSummary: Calcium channel blockers versus other classes of drugs for hypertension – Cochrane Library
Original Study: Calcium channel blockers versus other classes of drugs for hypertension – Cochrane Library
Commentary on Twitter
How do calcium channel blockers compare to other #antihypertensive drugs for #hypertension?💊
Our @CochraneLibrary systematic review looks at evidence from 23 RCTs involving 153,849 participants with #highbloodpressure
👉🏾https://t.co/dDLCY1RoOT#SystematicReviews #SysRev pic.twitter.com/zJ4JNRRf0L
— Cochrane Hypertension (@CochraneHTN) October 17, 2021
M-A: Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis – although Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be most effective treatments, topical diclofenac 70-81 mg/day is safer and should be considered as first line treatment.
17 Oct, 2021 | 21:14h | UTCNews release: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital
Commentary: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News
Commentary on Twitter
Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be the most effective oral NSAIDs for knee and hip osteoarthritis pain and physical function, but might not be appropriate in the presence of comorbidities or for long term use, concludes #BMJResearchhttps://t.co/rrtX3BnQE5
— The BMJ (@bmj_latest) October 16, 2021
M-A: Psychosocial and psychological interventions for relapse prevention in schizophrenia.
17 Oct, 2021 | 21:12h | UTC
Commentary on Twitter
An excellent SR/Network MA on #Psychosocial interventions for relapse prevention in #schizophrenia
Family interventions, family psychoeducation, & CBT are effective & must be prioritised in the care systems for patients with schizophrenia @TheLancetPsych https://t.co/d6xRw14fbT— Rajesh Mohan🌈 (@raj_psyc) October 16, 2021
Serious injury risk higher for horse riding than for football, motor racing, or skiing – “Chest most common site of injury, but head and neck injuries most lethal”.
17 Oct, 2021 | 21:08h | UTCNews release: Serious injury risk higher for horse riding than for football, motor racing, or skiing – BMJ
Commentary: Horse Riding More Dangerous Than Skiis And Motorcycles, Injury Data Reveal – Science Alert
Systematic Review: There is not enough evidence from randomized trials to inform about the effects of additional antihypertensive drugs in patients with hypertension‐induced left ventricular hypertrophy.
15 Oct, 2021 | 02:20h | UTCPharmacotherapy for hypertension‐induced left ventricular hypertrophy – Cochrane Library
Commentary on Twitter
What are the effects of added #antihypertensive drug therapy on morbidity/mortality of people with #LVH and #hypertension? 💊
Our @CochraneLibrary @CochraneHTN systematic review looks at evidence from 3 RCTs w/ 930 participants with #highbloodpressure
👉🏾https://t.co/d3dakCPW0B pic.twitter.com/ppCqKBU7K0
— Cochrane Hypertension (@CochraneHTN) October 11, 2021
M-A: Outcomes after transcatheter aortic valve replacement in bicuspid versus tricuspid anatomy – device success and 1-year survival rates are similar, but patients with bicuspid valves have a higher risk for periprocedural complications.
14 Oct, 2021 | 09:51h | UTC
Systematic Review: Direct oral anticoagulants (DOACs) may be beneficial for people being treated for cancer who have no therapeutic or prophylactic indication for anticoagulation.
14 Oct, 2021 | 09:44h | UTC
Systematic Review: Ultrasound guidance for arterial (other than femoral) catheterization in adults may improve first attempt and overall success rates compared to palpation.
14 Oct, 2021 | 09:41h | UTCUltrasound guidance for arterial (other than femoral) catheterisation in adults – Cochrane Library
M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.
13 Oct, 2021 | 01:27h | UTCEffect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis – Circulation (link to abstract – $ for full-text)
Related:
Commentary on Twitter
#OriginalResearch Omega-3 fatty acid supplementation is associated with increased risk of #AFib in meta-analysis of RCTs https://t.co/knv0P0lmnC #AHAJournals @bagencer @Hopitaux_unige @CMAlbertEP @CedarsSinai @BrighamWomens @HarvardChanSPH @harvardmed pic.twitter.com/5VIklN8lm8
— Circulation (@CircAHA) October 6, 2021
M-A: Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression.
10 Oct, 2021 | 21:34h | UTCSee calculator: PHQ-9 (Patient Health Questionnaire-9)
Commentary on Twitter
This new study investigates the accuracy of the Patient Health Questionnaire-9 (PHQ-9), the most commonly used depression screening tool in general practice, for detecting major depression https://t.co/9WoI3MofWH
— The BMJ (@bmj_latest) October 10, 2021
Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies.
10 Oct, 2021 | 21:31h | UTC
Systematic review: Pretomanid for tuberculosis.
6 Oct, 2021 | 08:51h | UTCPretomanid for tuberculosis: a systematic review – Clinical Microbiology and Infection
Related:
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
WHO announces updated definitions of extensively drug-resistant tuberculosis
RCT: Early computed tomography coronary angiography in patients with suspected acute coronary syndrome did not improve one year clinical outcomes.
3 Oct, 2021 | 22:35h | UTC
Commentary on Twitter
In this RCT, early CT coronary angiography in the emergency department for patients with suspected / provisional diagnosis of acute coronary syndrome had no effect on rate of death or subsequent non-fatal #heartattack at 1 year.@bmj_latest #Wondrmedicalhttps://t.co/usNKEGPDa4
— Prof Chris P Gale (@cpgale3) October 1, 2021
Systematic Review: Is exercise an effective therapy to treat long-lasting low back pain?
3 Oct, 2021 | 22:32h | UTCSummary: Is exercise an effective therapy to treat long-lasting low back pain? – Cochrane Library
Original Study: Exercise therapy for chronic low back pain – Cochrane Library
Commentary on Twitter
New @CochraneBack Cochrane review – 249 RCTs – ~25,000 participants – consistent, moderately strong evidence that #exercise treatment was more effective than no treatment or usual care for the management of chronic #backpain 📚 #systematicreview: https://t.co/X10rUtnNNb pic.twitter.com/O0AtZK2gZq
— Cochrane UK (@CochraneUK) October 2, 2021
Systematic Review: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness?
3 Oct, 2021 | 22:33h | UTCOriginal article: Effect of testing for cancer on cancer‐ or venous thromboembolism (VTE)‐related mortality and morbidity in people with unprovoked VTE – Cochrane Library
Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis.
1 Oct, 2021 | 10:17h | UTCCommentaries:
People who eat more dairy fat have lower risk of heart disease, study suggests – CNN
Systematic review: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities?
28 Sep, 2021 | 09:47h | UTC
M-A of randomized trials: Efficacy of exercise combined with standard treatment for depression compared to standard treatment alone.
28 Sep, 2021 | 08:55h | UTC
Commentary on Twitter
Meta-analysis: Exercise combined with standard treatments for depression is more effective than standard treatments alone. https://t.co/TlePIyvzo3 pic.twitter.com/h6eRoKFLUt
— Steve Stewart-Williams (@SteveStuWill) September 18, 2021
Systematic review: Instruments for assisted vaginal birth.
26 Sep, 2021 | 21:35h | UTCInstruments for assisted vaginal birth – Cochrane Library
Summary: Instruments for assisted vaginal birth – Cochrane Library
Systematic Review: Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnea.
26 Sep, 2021 | 21:36h | UTC
M-A: Treatment options for progression or recurrence of glioblastoma.
26 Sep, 2021 | 21:34h | UTCSummary: Treatment options for people with recurrent and progressive glioblastoma – Cochrane Library
Cochrane Special Collection | De-implementation of low-value health care: resource prioritization in the COVID-19 pandemic era.
23 Sep, 2021 | 10:13h | UTCEditorial: Making wise choices about low‐value health care in the COVID‐19 pandemic – Cochrane Library
Commentary: Choosing health care wisely when resources are scarce – Evidently Cochrane
Commentaries on Twitter
📰Our new editorial @cochranecollab: Making wise choices about low‐value health care in the COVID‐19 pandemic👉https://t.co/qABVg7emRi
Linked Special Collection on low-value care: https://t.co/fstV8P8OQS#FreeAccess pic.twitter.com/h9KZGUm2kp
— Juan Franco 🏳️🌈 (@juan_francomd) September 22, 2021
Sadly, some medical interventions are in use despite evidence against them. With @Cochrane_SH, we have published a Special Collection of Cochrane reviews of Low Value Care interventions and described the issue in an Editorial. We cannot afford wasted HC. https://t.co/PXUhaMZud2
— Karsten Juhl Jørgensen (@KarstenJuhl) September 22, 2021