General Interest
COVID-19 Vaccine Janssen: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets
21 Apr, 2021 | 07:07h | UTCCommentary: Johnson & Johnson vaccine: EU regulator says blood clot very rare side effect – BBC
Commentary on Twitter
EMA has concluded there is a possible link between TTS (thrombosis & thrombocytopenia syndrome) & the J&J vaccine, & they will be adding it as a rare side effect to the product information: the same as for AZ, but so far reported at a much lower rate…1/n https://t.co/aonOEObeHR
— Hilda Bastian, PhD (@hildabast) April 20, 2021
WHO panel comes out against requiring vaccination proof for travel
21 Apr, 2021 | 07:03h | UTCWHO panel comes out against requiring vaccination proof for travel – The Hill
Related: Opinion | How to lose friends and alienate people? On the problems of vaccine passports (several texts on the subject)
We know a lot about Covid-19. Experts have many more questions
21 Apr, 2021 | 07:02h | UTCWe know a lot about Covid-19. Experts have many more questions – STAT
Bioethics | COVID: Is it OK to manipulate people into getting vaccinated?
21 Apr, 2021 | 07:00h | UTCCOVID: Is it OK to manipulate people into getting vaccinated? – The Conversation
Study: Postprandial glycemic dips predict appetite and energy intake in healthy individuals
21 Apr, 2021 | 06:36h | UTCCommentaries: New research reveals why some of us are hungry all the time – King’s College London AND The easy test that predicts the size of your next few meals – Nature AND Feeling Hungry All The Time? Scientists Have a New Explanation For What’s Going On – Science Alert
Commentary on Twitter
Research published in @NatMetabolism reports that people who experience big dips in blood sugar levels several hours after eating end up feeling hungrier and consume more calories during the day than others. https://t.co/Nee9EYMUZ0 pic.twitter.com/VDgmvwiPjQ
— Nature Research (@nresearchnews) April 14, 2021
Perspective | The Confident Generalist: Putting The Primary Care Physician Back At The Center
20 Apr, 2021 | 05:35h | UTCThe Confident Generalist: Putting The Primary Care Physician Back At The Center – Health Affairs
[News release – not published yet] Sputnik V demonstrates 97.6% efficacy according to the analysis of data of 3.8 million vaccinated persons in Russia
20 Apr, 2021 | 06:08h | UTC
Commentary on Twitter
Press release from Russia on Sputnik V claiming effectiveness is 97.6% based on a comparison of the infection rate of people fully vaxed & those with confirmed Covid-19; says a publication in the works, but no mention of safety data…1/n https://t.co/7V5cbUxTSV
— Hilda Bastian, PhD (@hildabast) April 19, 2021
COVID-19 dynamics after a national immunization program in Israel
20 Apr, 2021 | 06:06h | UTCCOVID-19 dynamics after a national immunization program in Israel – Nature Medicine
Commentary on Twitter
Our paper on the effect of Israel's vaccination program now out @NatureMedicine https://t.co/ENpKjz21uu
Life is now back to normal except for masks in closed places
Vaccines pretty much eradicated COVID-19 from Israel, at least for the time being
— Eran Segal (@segal_eran) April 19, 2021
M-A: Prevalence of depression, anxiety and post-traumatic stress disorder in health care workers during the COVID-19 pandemic
20 Apr, 2021 | 06:00h | UTC
Ten scientific reasons in support of airborne transmission of SARS-CoV-2
18 Apr, 2021 | 21:51h | UTCTen scientific reasons in support of airborne transmission of SARS-CoV-2 – The Lancet
Animated Videos: Aerosols and making spaces safe – University of Oxford
Commentary on Twitter (thread – click for more)
Just out in @TheLancet what experts have said for a year
SARS-CoV2 spreads PRIMARILY via airborne route
Failure to act on this has hampered efforts to prevent spread of COVID
Thank you @trishgreenhalgh @linseymarr @kprather88 @j_g_allen, others who stuck to the evidence https://t.co/uuJcUIKWHE
— Ashish K. Jha, MD, MPH (@ashishkjha) April 16, 2021
Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission
18 Apr, 2021 | 21:49h | UTCIndoor Air Changes and Potential Implications for SARS-CoV-2 Transmission – JAMA
Commentary on Twitter (thread – click for more)
In this new piece in @JAMA_current, I teamed up w/ colleague @AndrewMIbrahim to argue that
1) evidence for airborne spread is strong
2) enhanced ventilation/filtration is needed
3) 4-6 air changes per hour should be target for small volume spacesTHREADhttps://t.co/bvdZkyy03j
— Joseph Allen (@j_g_allen) April 16, 2021
A guideline to limit indoor airborne transmission of COVID-19
18 Apr, 2021 | 21:47h | UTC
Editorial: SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – “The very low prevalence of this complication of vaccination, however severe, relative to the benefits of preventing Covid-19 must be emphasized”
18 Apr, 2021 | 21:42h | UTCSARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – New England Journal of Medicine
Study: Double masking improves protection from Covid-19 mostly by eliminating any gaps or poor-fitting areas of a mask
18 Apr, 2021 | 21:37h | UTCFitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic – JAMA Internal Medicine
Commentaries: Fit matters most when double masking to protect yourself from COVID-19 – University of North Carolina Health Care AND Check your fit on that double mask if you want it to work against Covid, study says – CNN
Study shows past COVID-19 infection doesn’t fully protect young people against reinfection
18 Apr, 2021 | 21:35h | UTCOriginal study: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study – The Lancet Respiratory Medicine
Commentary on Twitter
Risk of covid reinfection in a prospective study of >3,000 Marine recruits
Prior covid: 82% reduced compared w/ no prior covid (+ when reinfections occurred, much less viral loads)
Protection correlated w/ higher spike IgG antibody levels https://t.co/7Jl154lwDX @LancetRespirMed pic.twitter.com/xKVLKm8AA6— Eric Topol (@EricTopol) April 15, 2021
Case report: Energy drink-induced cardiomyopathy
18 Apr, 2021 | 21:00h | UTCEnergy drink-induced cardiomyopathy – BMJ Case Reports
Commentaries: Student’s heart failure linked to ‘excessive’ energy drinks – BBC AND Heavy energy drink consumption linked to heart failure in a young man – BMJ
Study shows antihistamines may impair response to exercise training
16 Apr, 2021 | 06:06h | UTCCommentary: Histamine-suppressing drugs found to reduce benefits of exercise – MedicalXpress
Commentary on Twitter (thread – click for more)
Extremely excited to finally share our newest paper: Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans. Published today in @ScienceAdvances. A thread: (1/12)https://t.co/R4FNiKWyG9 pic.twitter.com/U2HFHOY9eA
— Thibaux Van der Stede (@ThibauxV) April 14, 2021
[Preprint] Risk of rare blood clotting much higher for COVID-19 than for vaccines
16 Apr, 2021 | 06:37h | UTCNews release: Risk of rare blood clotting higher for COVID-19 than for vaccines – University of Oxford
Original study (preprint): Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine
Commentaries: Brain clots ‘more likely’ with Covid infection than vaccine – BBC AND Risk for Cerebral Venous Thrombosis Elevated After COVID-19 Diagnosis – NEJM Journal Watch AND Study: COVID much more likely than vaccines to cause blood clots – CIDRAP
Commentary on Twitter
There is an interesting new preprint out that will probably generate a lot of coverage at least in the UK. Essentially it argues that the risk of CVST is much higher from #covid19 than from vaccines.
Quick thread on this:https://t.co/0MdDU2z9bp— Kai Kupferschmidt (@kakape) April 15, 2021
CDC study suggests leaving middle seat empty could lower COVID-19 spread on planes by 23% to 57%
16 Apr, 2021 | 06:33h | UTCCommentaries: Keeping middle seats vacant on airplanes can reduce risk of Covid-19 exposure by up to 57%, CDC study says – CNN AND Leaving middle seat empty lowers COVID-19 spread on planes, modeling suggests – LiveScience
Video | Coronavirus variants: What you need to know
16 Apr, 2021 | 06:32h | UTCCoronavirus variants: What you need to know – Nature Video
M-A: Treatment with hydroxychloroquine is associated with increased mortality in COVID-19 patients
16 Apr, 2021 | 06:30h | UTC
Commentaries on Twitter
The use of hydroxychloroquine in COVID19 will be remembered as one of the worst examples of medicine going against its core principle:
First Do No Harm. https://t.co/PGq4D5pJ1H— Maurizio Cecconi (@DrMCecconi) April 15, 2021
What collaboration can achieve
Just out in @NatureComms our meta-analysis of 14 unpublished & 14 published RCTs on Hydroxychloroquine/ Choloroquine
Thanks so much to the great team – and special thanks for rapidly sharing the data of unpublished trials!https://t.co/Dg1DmAx1Kq
— Lars G. Hemkens (@LGHemkens) April 15, 2021
Perspective | Ivermectin is the new Hydroxychorloquine
16 Apr, 2021 | 06:28h | UTCIvermectin is the new Hydroxychorloquine – Science-Based Medicine
Editorial: Covid-19 has redefined airborne transmission
16 Apr, 2021 | 06:26h | UTCCovid-19 has redefined airborne transmission – The BMJ
Commentaries: Future attempts to reduce Covid-19 spread should focus on tackling airborne transmission – News Medical AND Open the windows to curb COVID spread: experts – MedicalXpress
Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more) AND Deep Cleaning Isn’t a Victimless Crime – The Atlantic
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – “we estimate that P.1 may be 1.7–2.4-fold more transmissible”
15 Apr, 2021 | 07:09h | UTCGenomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science
Commentary: The P.1 coronavirus variant is twice as transmissible as earlier strains – ScienceNews
Vaccines alone will not stop Covid spreading – here’s why (visual guide to the “Swiss cheese model”)
15 Apr, 2021 | 06:53h | UTCVaccines alone will not stop Covid spreading – here’s why – BBC