Otolaryngology/Head and Neck (all articles)
RCT | Upfront radiosurgery reduces tumor volume vs. a wait-and-scan approach in small- to medium-sized vestibular schwannoma
7 Aug, 2023 | 14:40h | UTCUpfront Radiosurgery vs a Wait-and-Scan Approach for Small- or Medium-Sized Vestibular Schwannoma: The V-REX Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
Commentary on Twitter
Among patients with small or medium vestibular schwannoma, a treatment strategy consisting of upfront radiosurgery was more effective at reducing tumor volume at 4 years than was the initial wait-and-scan approach. https://t.co/Qv3YZVsq2Q pic.twitter.com/aNeu7MJfl0
— JAMA (@JAMA_current) August 2, 2023
RCT | Limited antibiotic efficacy in children with sinusitis lacking nasopharyngeal pathogens
27 Jul, 2023 | 13:08h | UTCIdentifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Acute Bacterial Sinusitis: Limitations of Test-Based Treatment – JAMA (free for a limited period)
News Release: Bacterial testing in kids with sinusitis could slash antibiotic use – University of Pittsburgh
Commentary: Trial suggests bacterial test could reduce antibiotics in kids with sinusitis – CIDRAP
Commentary on Twitter
In children with acute sinusitis, antibiotic treatment had minimal benefit for those without nasopharyngeal bacterial pathogens. The antibiotic effect did not depend on the color of nasal discharge. https://t.co/hgRx1Qou53 pic.twitter.com/zYs8Mfbjjp
— JAMA (@JAMA_current) July 26, 2023
Review | The evolving landscape of salivary gland tumors
27 Jul, 2023 | 12:58h | UTCThe evolving landscape of salivary gland tumors – CA: A Cancer Journal for Clinicians
RCT | Dysphagia-optimized intensity-modulated radiotherapy better preserves swallowing function in pharyngeal cancer patients
25 Jul, 2023 | 13:52h | UTCCommentaries:
Radiation approach improves swallowing in head, neck cancer – MDedge
Commentary on Twitter
NOW OF: The (DARS) phase 3 RCT investigates if dysphagia-optimised intensity-modulated radiotherapy (IMRT) reduces radiation dose to the dysphagia and aspiration related structures and improves swallowing function compared with standard IMRT.#hncsmhttps://t.co/CzpxsNxx1N pic.twitter.com/xNgfm43tHE
— The Lancet Oncology (@TheLancetOncol) July 7, 2023
RCT | Hearing intervention fails to impact 3-year cognitive decline in older adults
20 Jul, 2023 | 11:09h | UTCHearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
#AAIC23 While hearing aids did not have an impact on cognitive decline over 3 years in a general population, treating hearing loss protected against cognitive decline in older adults at greater risk of dementia, finds a new trial: https://t.co/1UjGgDf5m5 pic.twitter.com/kuujeekCWW
— The Lancet (@TheLancet) July 18, 2023
TTMV-HPV DNA testing | Promising diagnostic and surveillance tool for HPV-linked oropharyngeal cancer
17 Jul, 2023 | 13:25h | UTCPerformance of Liquid Biopsy for Diagnosis and Surveillance of Human Papillomavirus–Associated Oropharyngeal Cancer – JAMA Otolaryngology–Head & Neck Surgery (free for a limited period)
Invited Commentary: Circulating Human Papillomavirus Tumor DNA—Ready for Prime Time? – – JAMA Otolaryngology–Head & Neck Surgery (free for a limited period)
2023 ETA clinical practice guidelines for thyroid nodule management
12 Jul, 2023 | 13:48h | UTC
The 2023 Bethesda System for reporting thyroid cytopathology
12 Jul, 2023 | 13:46h | UTCThe 2023 Bethesda System for Reporting Thyroid Cytopathology – Thyroid
RCT | Semont-plus maneuver yields faster recovery than Epley maneuver in posterior canal BPPV
7 Jul, 2023 | 16:26h | UTCThe Semont-Plus Maneuver or the Epley Maneuver in Posterior Canal Benign Paroxysmal Positional Vertigo: A Randomized Clinical Study – JAMA Neurology (link to abstract – $ for full-text)
See also: Visual Abstract
Videos:
Demonstration of the Semont-Plus Self-maneuver for Right Posterior Canal Canalithiasis
Semont-Plus Maneuver for Right Posterior Canal Benign Paroxysmal Positional Vertigo
Demonstration of the Epley Self-maneuver for a Right Posterior Canal Canalithiasis
Commentary: Semont-plus Meneuver Offered Faster Recovery for Benign Paroxysmal Positional Vertigo – Neurology Today
Editorial | How to become a good surgeon
22 Jun, 2023 | 15:12h | UTCHow to become a good surgeon – Advances in Ophthalmology Practice and Research
M-A | Role of chemotherapy in patients with nasopharynx carcinoma treated with radiotherapy
5 Jun, 2023 | 13:29h | UTCRole of chemotherapy in patients with nasopharynx carcinoma treated with radiotherapy (MAC-NPC): an updated individual patient data network meta-analysis – The Lancet Oncology (free for a limited period)
Commentary from the author on Twitter
Our latest meta-analysis on #chemoradiation in nasopharyngeal cancer out in @TheLancetOncol
Huge collaborative work.
✅ 28 trials, 8.000+ pts, 7.6y FU
✅ more chemo (ind+conc or conc+adj) ➡️superior (OS/PFS) to CRT alone but more toxFree 50day link: https://t.co/BtRJDZERRZ pic.twitter.com/v2v5MsinnV
— Pierre Blanchard, MD (@PBlanchardMD) June 1, 2023
RCT | Tonsillectomy shown to be clinically and cost-effective in adults with recurrent acute tonsillitis
23 May, 2023 | 13:06h | UTCSummary: The NATTINA trial, a pragmatic multicentre, open-label, randomized controlled study, sought to compare the clinical and cost-effectiveness of conservative management versus tonsillectomy in adults with recurrent acute tonsillitis. Conducted across 27 UK hospitals, 453 participants aged 16 or older were randomly assigned to either undergo immediate tonsillectomy or receive standard non-surgical care.
The main finding was that participants in the immediate tonsillectomy group had fewer days of sore throat over a 24-month period than those in the conservative management group (median 23 vs. 30 days). After adjusting for site and baseline severity, the incident rate ratio of total sore throat days in the immediate tonsillectomy group was significantly lower than in the conservative management group (0.53, 95% CI 0.43 to 0.65, p < 0.0001). The most common adverse event related to tonsillectomy was bleeding, which occurred in 19% of participants.
The NATTINA trial is the largest to date assessing the clinical and cost-effectiveness of tonsillectomy in adults. The results indicate that immediate tonsillectomy is clinically effective and cost-effective for recurrent acute tonsillitis. However, patients should weigh the benefits of fewer sore throat days against the risks of surgery.
News Release: Tonsillectomy both clinically and cost effective for adults – Newcastle University
Commentary on Twitter
Compared with conservative management, immediate tonsillectomy is clinically effective and cost-effective in adults with recurrent acute #tonsillitis, suggests trial. https://t.co/LvSjn6XUx0 pic.twitter.com/yKzH9RqY5J
— The Lancet (@TheLancet) May 18, 2023
Fluorescence-guided surgery: comprehensive review
18 May, 2023 | 13:34h | UTCFluorescence-guided surgery: comprehensive review – BJS Open
Commentary on Twitter
Find all you ever wanted to know about the current state of fluorescence-guided surgery 🟢🔬🔪in our latest comprehensive review by @BJSurgery editor @paulo_sutt et al. Absolutely worth reading!https://t.co/Tgrj4UvOzV@BJSAcademy @juliomayol @young_bjs #SoMe4Surgery #MedTwitter pic.twitter.com/ReArdO1LOs
— BJS Open (@BjsOpen) May 17, 2023
Ear-related balance disorders: evidence and resources
11 May, 2023 | 12:14h | UTCEar-related balance disorders: evidence and resources – Evidently Cochrane
Olfactory dysfunction: etiology, diagnosis, and treatment
11 May, 2023 | 11:50h | UTCOlfactory Dysfunction: Etiology, Diagnosis, and Treatment – Deutsches Ärzteblatt International
M-A | Association of SARS-CoV-2 vaccination or infection with Bell palsy
10 May, 2023 | 16:03h | UTC
Review | Updated salivary gland immunohistochemistry
5 May, 2023 | 14:55h | UTCUpdated Salivary Gland Immunohistochemistry: A Review – Archives of Pathology & Laboratory Medicine
RCT | Effectiveness of an over-the-counter self-fitting hearing aid compared with an audiologist-fitted hearing aid
25 Apr, 2023 | 14:47h | UTCAuthor Interview: Effectiveness of Self-fitting vs Audiologist-Fitted Hearing Aids – JAMA
Commentaries:
Self-Fitting, Over-the-Counter Hearing Aids Beneficial – HealthDay
How Do Over-the-Counter Hearing Aids Compare with Those Fitted by Audiologists? – NEJM Journal Watch (free for a limited period)
Commentary on Twitter
Findings suggest that a self-fitting OTC hearing aid may be an effective intervention option for individuals with mild to moderate #hearingloss and produce self-perceived and clinical outcomes similar to those of an audiologist-fitted #hearingaid. https://t.co/Zbc8URj2uA
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) April 13, 2023
Study shows that parathyroidectomy in adults with primary hyperparathyroidism probably has no effect on kidney function
21 Apr, 2023 | 12:57h | UTCEstimated Effect of Parathyroidectomy on Long-Term Kidney Function in Adults With Primary Hyperparathyroidism – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
New: #parathyroidectomy had no effect on long term #KidneyFunction in older adults w/ primary #hyperparathyroidism, but may preserve function in patients under 60. https://t.co/B456rPwGem pic.twitter.com/V8hLmrYiUX
— Annals of Int Med (@AnnalsofIM) April 17, 2023
M-A | Test characteristics of ultrasound for the diagnosis of peritonsillar abscess
19 Apr, 2023 | 13:15h | UTCCommentary: How Good is Ultrasound at Diagnosing PTA? – RebelEM
Cohort Study | Association between hearing aid use and all-cause and cause-specific dementia
17 Apr, 2023 | 13:07h | UTCCommentaries: Preventing dementia through correcting hearing: huge progress but more to do – The Lancet Public Health
News Release: Hearing aids may protect against a higher risk of dementia associated with hearing loss, study suggests – Lancet
Related:
M-A | Association of hearing aids and cochlear implants with cognitive decline and dementia
Dementia and hearing-aid use: a two-way street – Age and Ageing
Association of Hearing Loss With Dementia – JAMA Network Open
Commentary on Twitter
NEW—Hearing aids may protect against a higher risk of #dementia associated with hearing loss, a @TheLancetPH study suggests.https://t.co/Yliq2wT7SR pic.twitter.com/v3iuTuHYVI
— The Lancet (@TheLancet) April 13, 2023
RCT | Targeted hypoglossal nerve stimulation may benefit patients with obstructive sleep apnea
11 Apr, 2023 | 14:07h | UTC
Commentary on Twitter
In this study, proximal targeted hypoglossal nerve responses proved safe and effective in treating sleep apnea and improving sleep architecture and quality of life, while comparing favorably with those in distal hypoglossal nerve stimulation trials. https://t.co/yorNGW9uoi
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) April 6, 2023
Consensus Paper | Best management of patients with an acute sore throat
6 Apr, 2023 | 13:32h | UTC
Cochrane Library | Hearing conditions: evidence, experience and resources
4 Apr, 2023 | 13:36h | UTCHearing conditions: evidence, experience and resources – Evidently Cochrane
SR | Etiologies of vertigo in the elderly
31 Mar, 2023 | 13:38h | UTCVertigo in the Elderly: A Systematic Literature Review – Journal of Clinical Medicine