Otolaryngology/Head and Neck (all articles)
M-A of randomized trials | Prophylactic central neck lymph node dissection in low-risk thyroid carcinoma patients does not decrease the incidence of locoregional recurrence.
21 Sep, 2022 | 13:07h | UTCProphylactic Central Neck Lymph Node Dissection in Low-risk Thyroid Carcinoma Patients Does Not Decrease the Incidence of Locoregional Recurrence: A Meta-analysis of Randomized Trials – Annals of Surgery (link to abstract – $ for full-text)
International consensus statement on obstructive sleep apnea.
8 Sep, 2022 | 14:41h | UTCInternational consensus statement on obstructive sleep apnea – Allergy & Rhinology (PDF)
M-A | Hypocalcemia following thyroidectomy among patients who have previously undergone bariatric surgery.
8 Sep, 2022 | 14:25h | UTCHypocalcaemia following thyroidectomy among patients who have previously undergone bariatric surgery: systematic review and meta-analysis – British Journal of Surgery (link to abstract – $ for full-text)
Guideline | Patient preparation and radiation protection guidance for adult patients undergoing radioiodine treatment for thyroid cancer.
1 Sep, 2022 | 11:53h | UTC
RCT | In patients with low-risk nasopharyngeal carcinoma, radiotherapy alone was noninferior to radiotherapy plus concurrent chemoradiotherapy on survival without disease relapse at 3 years.
25 Aug, 2022 | 12:13h | UTCEffect of Radiotherapy Alone vs Radiotherapy With Concurrent Chemoradiotherapy on Survival Without Disease Relapse in Patients With Low-risk Nasopharyngeal Carcinoma: A Randomized Clinical Trial – JAMA (free for a limited period)
Video Editor’s Note: Radiotherapy With vs Without Chemoradiotherapy in Low-risk Nasopharyngeal Carcinoma – JAMA
Guidelines for clinical assessment and management of adult cochlear implantation for single-sided deafness.
24 Aug, 2022 | 14:13h | UTC
The contemporary management of cancers of the sinonasal tract in adults.
16 Aug, 2022 | 13:39h | UTC
Systematic Review | Psychological therapies for temporomandibular disorders.
15 Aug, 2022 | 11:39h | UTCPsychological therapies for temporomandibular disorders (TMDs) – Cochrane Library
Consensus Statement | Pharmacological management of allergic rhinitis.
11 Aug, 2022 | 12:10h | UTCRelated:
RCT | Effect of intranasal Dexmedetomidine or Midazolam for premedication on the occurrence of respiratory adverse events in children undergoing tonsillectomy and adenoidectomy.
11 Aug, 2022 | 12:08h | UTCCommentaries:
Dexmedetomidine Cuts Perioperative Respiratory AEs in Tonsillectomy – HealthDay
Commentary on Twitter
Children often required sedatives before surgery due to anxiety and crying. In this RCT, intranasal midazolam increased the incidence of perioperative respiratory adverse events (PRAEs), while intranasal dexmedetomidine reduced PRAEs. #OrigInvestigation https://t.co/5AAILuzstM pic.twitter.com/WejpGkAGGs
— JAMA Network Open (@JAMANetworkOpen) August 9, 2022
M-A | Global prevalence and incidence of tinnitus.
9 Aug, 2022 | 12:57h | UTCGlobal Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
Commentary: Review: Global Pooled Prevalence of Tinnitus 14.4 Percent – HealthDay
Commentary on Twitter
The global burden of #tinnitus is large, similar to #migraine and pain, and the lack of effective treatment options justifies a major investment in research in this area. https://t.co/9uVJmnYh9c
— JAMA Neurology (@JAMANeuro) August 8, 2022
Cohort Study | Rapid loss of smell predicts dementia and smaller brain areas linked to Alzheimer’s.
1 Aug, 2022 | 11:49h | UTCNews Release: Rapid loss of smell predicts dementia and smaller brain areas linked to Alzheimer’s – University of Chicago Medical Center
Original Study: Rapid olfactory decline during aging predicts dementia and GMV loss in AD brain regions – Alzheimer’s & Dementia
Guideline | Pediatric differentiated thyroid carcinoma.
29 Jul, 2022 | 12:31h | UTC
M-A | Prognosis and persistence of smell and taste dysfunction in patients with covid-19.
28 Jul, 2022 | 13:28h | UTCEditorial: Smell and taste dysfunction after covid-19 – The BMJ
Commentary: The burden of prolonged smell and taste loss in covid-19 – The BMJ
News Release: Millions of covid patients may have long term smell and taste problems – BMJ Newsroom
Consensus on magnetic resonance imaging of endolymphatic hydrops in patients with suspected hydropic ear disease (Meniere).
26 Jul, 2022 | 12:40h | UTCEditorial: Editorial: Hydropic Ear Disease: Imaging and Functional Evaluation – Frontiers in Surgery
Commentary: Guidance Issued for MR Imaging of Endolymphatic Hydrops – HealthDay
Systematic Review | Intratympanic corticosteroids for sudden sensorineural hearing loss.
26 Jul, 2022 | 11:42h | UTCIntratympanic corticosteroids for sudden sensorineural hearing loss – Cochrane Library
Summary: Treatment of sudden hearing loss with corticosteroids applied into the middle ear – Cochrane Library
M-A | Antihistamines are better than benzodiazepines for symptomatic control in patients with acute vertigo.
25 Jul, 2022 | 12:52h | UTCEfficacy of Benzodiazepines or Antihistamines for Patients With Acute Vertigo: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)
Commentary on Twitter
Study found #benzodiazepines were inferior to #antihistamines for immediate relief of acute #vertigo. Benzodiazepine use is not supported by randomized controlled data for improvement in any outcomes related to acute vertigo. https://t.co/e9NQ1hFMIK
— JAMA Neurology (@JAMANeuro) July 18, 2022
RCT | Intranasal corticosteroids not beneficial for children with obstructive sleep apnea.
19 Jul, 2022 | 13:27h | UTCA trial of intranasal corticosteroids to treat the childhood obstructive sleep apnea syndrome – CHEST (link to abstract – $ for full-text)
Commentaries:
Intranasal corticosteroids not recommended for most children with OSA: study – Medical Dialogues
Commentary on Twitter
In children with obstructive sleep apnea syndrome, treatment with intranasal corticosteroids did not result in significant polysomnographic, neurobehavioral, and symptom changes compared to placebo, according to research in @journal_CHEST. https://t.co/e4bt4NMv5Z pic.twitter.com/FrIBdoMABf
— American Academy of Sleep Medicine (@AASMorg) July 11, 2022
Phase 2 RCT | Deintensified chemoradiotherapy for pretreatment Epstein-Barr Virus DNA-selected low-risk locoregionally advanced nasopharyngeal carcinoma.
19 Jul, 2022 | 12:58h | UTCDeintensified Chemoradiotherapy for Pretreatment Epstein-Barr Virus DNA-Selected Low-Risk Locoregionally Advanced Nasopharyngeal Carcinoma: A Phase II Randomized Noninferiority Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries:
Commentary on Twitter
Less is more? 🤔 2-cycle cisplatin concurrent chemoradiotherapy is not inferior to 3-cycles based on 3-yr PFS in treating locoregionally advanced nasopharyngeal ca w/preRX EBV DNA levels < 4000.QOL & toxicity improved w/ less chemo https://t.co/XovHi2P06W pic.twitter.com/JJqiC8wnWW
— Journal of Clinical Oncology (@JCO_ASCO) January 25, 2022
RCT | Efficacy and safety of ciprofloxacin plus fluocinolone acetonide among patients with acute otitis externa.
15 Jul, 2022 | 12:43h | UTC
Commentary on Twitter
In this randomized clinical trial, ciprofloxacin 0.3% plus fluocinolone acetonide 0.025% otic solution was efficacious and safe in treating acute otitis externa. https://t.co/VRf1vEojY1
— JAMA Network Open (@JAMANetworkOpen) July 14, 2022
Consensus Statement | Informed consent for suspension microlaryngoscopy.
14 Jul, 2022 | 12:44h | UTC
Evaluation of the molecular landscape of pediatric thyroid nodules and use of a multigene genomic classifier in children.
8 Jul, 2022 | 11:20h | UTC
Commentaries on Twitter
A multigene classifier reveals that malignant pediatric thyroid nodules have a unique molecular landscape vs those in adults. The classifier had a sensitivity of 96% & specificity of 78% for cancer detection & might reduce the need for diagnostic surgery: https://t.co/hdsPjGe9IR
— NatureRevClinOncol (@NatRevClinOncol) June 16, 2022
Pediatric thyroid cancer is on the rise. Its genomic landscape is unique; but, this retrospective case series shows that it may still be amenable to molecular classification—potentially decreasing diagnostic surgery & opening avenues for targeted therapy. https://t.co/KiYMsB1qGM
— JAMA Oncology (@JAMAOnc) June 10, 2022
Retrospective Cohort Study | Magnetic resonance imaging prognostic findings for visual and mortality outcomes in acute invasive fungal rhinosinusitis.
6 Jul, 2022 | 11:16h | UTCReview | Cough hypersensitivity and chronic cough.
4 Jul, 2022 | 12:59h | UTCCough hypersensitivity and chronic cough – Nature Reviews Disease Primers (if the link is paywalled, try this one)
See also: Infographic (if the link is paywalled, try this one)
Commentary on Twitter
#Cough is mediated by a complex set of neurobiological processes involving the peripheral nervous system, brainstem and higher brain. #ChronicCoughhttps://t.co/DGgjk2Iyji pic.twitter.com/nrmJne7Ir8
— Nature Reviews Disease Primers (@DiseasePrimers) July 2, 2022
Consensus Guidelines: Management of hematoma after thyroid surgery.
30 Jun, 2022 | 11:06h | UTC