Spine
RCT | Investigational 4-Antigen Staphylococcus aureus vaccine fails to prevent infections in spinal surgery
12 May, 2023 | 13:12h | UTC
Commentary on Twitter
Efficacy of a 4-Antigen Staphylococcus aureus Vaccine in Spinal Surgery: The STRIVE Randomized Clinical Trial
✅ Just Accepted
🔓 Open Access
🔗 https://t.co/eFVufc7rzi pic.twitter.com/XdylTWa66v— Clinical Infectious Diseases (@CIDJournal) May 3, 2023
RCT | Cognitive functional therapy with or without biofeedback outperforms usual care for chronic low back pain relief
10 May, 2023 | 15:58h | UTCCognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial – The Lancet (link to abstract – $ for full-text)
News Release: Fresh hope for Australians living with chronic back pain – Curtin University
SR | Diagnostic accuracy of tests for disc, sacroiliac, and facet joint origins in low back pain assessment
10 May, 2023 | 15:44h | UTC
ESTES recommendation on thoracolumbar spine fractures
10 May, 2023 | 15:40h | UTC
Treating long-lasting low back pain without surgery: the latest evidence
4 May, 2023 | 13:40h | UTCTreating long-lasting low back pain without surgery: the latest evidence – Evidently Cochrane
M-A | Efficacy of erector spinae plane block for postoperative analgesia lumbar surgery
26 Apr, 2023 | 13:53h | UTC
M-A | Surgical versus non-surgical treatment for sciatica
25 Apr, 2023 | 14:39h | UTCEditorial: Early surgery for sciatica – The BMJ
News Release: Surgery for sciatica reduces leg pain and disability, but benefits are short-lived – University of Oxford
Commentary on Twitter
Very low to low certainty evidence suggests that discectomy was superior to non-surgical treatment or epidural steroid injections in reducing leg pain and disability in people with sciatica with a surgical indication, but the benefits reduced over timehttps://t.co/kHL2HBNscF
— The BMJ (@bmj_latest) April 19, 2023
Consensus Paper | Management of pathological thoracolumbar vertebral fractures in patients with multiple myeloma
25 Apr, 2023 | 14:11h | UTC
Geriatric odontoid fractures: treatment algorithms based on expert consensus and a systematic review
25 Apr, 2023 | 14:08h | UTC
RCT | Stereotactic radiosurgery vs. conventional radiotherapy for localized vertebral metastases of the spine
24 Apr, 2023 | 13:37h | UTCStereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Audio interview: Radiosurgery of Spine Metastasis—NRG/RTOG 0631 RCT Final Results – JAMA
Commentary on Twitter
Phase 3 rand trial of spinal radiosurgery vs. conventional external beam radiation therapy for pts w/spinal metastases showed radiosurgery did not significantly improve pain response at 3mo but showed feasibility that makes it widely used today. https://t.co/LvZY1nbUpS #RadOnc
— JAMA Oncology (@JAMAOnc) April 20, 2023
Low back pain of disc, sacroiliac joint, or facet joint origin: a diagnostic accuracy systematic review
12 Apr, 2023 | 13:17h | UTC
Pharmacological treatments for low back pain in adults: an overview of Cochrane Reviews
11 Apr, 2023 | 14:39h | UTCRelated:
SR | Nonopioid pharmacological management of acute low back pain
M-A | Limited evidence for analgesic effectiveness in acute low back pain treatment
M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain
Guideline Interventions for the management of acute and chronic low back pain.
M-A: Little benefit from muscle relaxants for adults with non-specific low back pain.
SR | Nonopioid pharmacological management of acute low back pain
31 Mar, 2023 | 13:27h | UTC
RCT | Drain usage may increase the length of hospital stay following lumbar arthrodesis
31 Mar, 2023 | 13:18h | UTCCommentary: Wound drains increase hospital los after lumbar surgery? – Orthopedics This Week
M-A | Limited evidence for analgesic effectiveness in acute low back pain treatment
29 Mar, 2023 | 13:32h | UTCSummary: The objective of this systematic review and network meta-analysis was to assess the effectiveness and safety of various analgesic medicines for treating acute non-specific low back pain. After examining 98 randomized controlled trials with over 15,000 participants, the study found that the quality of evidence for the effectiveness and safety of these medications is low or very low.
Some analgesic medicines showed potential in reducing pain intensity, but the evidence was limited due to trial risk of bias and imprecision in effect estimates. Furthermore, certain medications might increase the risk of adverse events during treatment, with evidence ranging from moderate to very low confidence.
Given the lack of high-quality evidence, clinicians and patients are advised to be cautious when using analgesic medicines for acute non-specific low back pain. More robust head-to-head comparison trials are needed to provide clearer guidance on the best course of treatment.
News Release: Study finds “considerable uncertainty” around effectiveness and safety of analgesics for low back pain – BMJ Newsroom
Commentary from the author on Twitter (thread – click for more)
Out today in @bmj_latest.
We found “considerable uncertainty” around the effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain.
Available at https://t.co/PeOmEOeJyJ
Thread 🧵 pic.twitter.com/T8YDNGhhME
— Michael Wewege (@mawewege) March 22, 2023
Global validation of the AO Spine Upper Cervical Injury Classification
16 Mar, 2023 | 12:58h | UTCGlobal Validation of the AO Spine Upper Cervical Injury Classification – Spine
Review | MRI image features with an evident relation to low back pain
15 Mar, 2023 | 15:01h | UTC
Consensus Recommendations | Spinal tumors
9 Mar, 2023 | 14:15h | UTC
SR | Spinal cord stimulation for low back pain provides no sustained clinical benefits compared to placebo
9 Mar, 2023 | 14:12h | UTCSummary: Spinal cord stimulation (SCS) is a surgical procedure used to treat persistent low back pain by sending electrical signals via implanted electrodes into the spinal cord. The review included 13 studies (randomized controlled trials and cross‐over trials) with 699 participants.
Most of the studies were focused on short-term effects (less than one month), but the review found it is uncertain whether spinal cord stimulation can improve outcomes in the immediate term compared with placebo. At six months, SCS probably does not improve back or leg pain, function, or quality of life compared with placebo, with moderate certainty of evidence. Adverse events were also reported, including infections, neurological damage, and lead migration requiring repeated surgery.
The review concluded that the data does not support the use of SCS to manage low back pain outside a clinical trial. Current evidence suggests SCS probably does not have sustained clinical benefits that would outweigh the costs and risks of this surgical intervention.
Article: Spinal cord stimulation for low back pain – Cochrane Library
Summary: Spinal cord stimulation for low back pain – Cochrane Library
Commentary from the author on Twitter
Our Cochrane review on spinal cord stimulators for #backpain out today.
Bottom line:
-Mod certainty evidence of no benefit vs placebo in medium term
-Uncertain if benefit on pain in immediate term
-Adverse events (infection, re-operation) commonhttps://t.co/lNJQeN96Zs— Adrian Traeger (@adrian_traeger) March 7, 2023
Chronic low back pain: a narrative review of recent international guidelines for diagnosis and conservative treatment
27 Feb, 2023 | 12:46h | UTC
SR | Nonopioid pharmacological management of acute low back pain
27 Feb, 2023 | 12:42h | UTCCommentary: Which Meds are Best for Acute Low Back Pain? – RheumNow
Related:
M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain
Guideline Interventions for the management of acute and chronic low back pain.
M-A: Little benefit from muscle relaxants for adults with non-specific low back pain.
Consensus Paper | Acute lower extremity fracture management in chronic spinal cord injury
23 Feb, 2023 | 13:36h | UTCCommentary: Updated spine fracture practice guidelines released – Orthopedics This Week
Spinal cord injury: the global incidence, prevalence, and disability from the Global Burden of Disease Study 2019
9 Feb, 2023 | 13:20h | UTCCommentary: Measures needed to combat growing incidence and burden of spinal cord injury – Spinal News International
Consensus Paper | Physical therapy for upper cervical instability in patients with symptomatic generalized joint hypermobility
7 Feb, 2023 | 14:01h | UTC
M-A | Effect of aquatic physical therapy on chronic low back pain
3 Feb, 2023 | 13:57h | UTC