Oncology – Brain
M-A | Extent of tumor resection and survival in pediatric patients with high-grade gliomas.
17 Aug, 2022 | 14:00h | UTC
Commentary on Twitter
In this systematic review and meta-analysis of pediatric high-grade gliomas, gross total resection was associated with better overall survival than subtotal resection and biopsy. https://t.co/QpKiDKpYYs
— JAMA Network Open (@JAMANetworkOpen) August 16, 2022
ASTRO Guideline | Radiation therapy for IDH-mutant grade 2 and grade 3 diffuse glioma.
29 Jul, 2022 | 12:33h | UTC
Single-arm study | Intensive multimodality therapy for extraocular retinoblastoma.
21 Jul, 2022 | 12:25h | UTCIntensive Multimodality Therapy for Extraocular Retinoblastoma: A Children’s Oncology Group Trial (ARET0321) – Journal of Clinical Oncology (link to abstract – $ for full-text)
The Global Retinoblastoma Outcome Study | A prospective, cluster-based analysis of 4,064 patients from 149 countries.
14 Jul, 2022 | 12:16h | UTCInvited Commentary: Retinoblastoma as a lens for correctable disparities worldwide – The Lancet Global Health
Phase II RCT | Proton craniospinal irradiation vs. photon involved-field radiotherapy for patients with solid tumor leptomeningeal metastasis.
13 Jul, 2022 | 11:09h | UTCRandomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis – Journal of Clinical Oncology (link to abstract – $ for full-text)
Phase 1 single-arm study | Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma.
4 Jul, 2022 | 12:08h | UTCOncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Oncolytic Virus Infusion Promising as Brain-Stem Glioma Treatment — Phase I trial shows encouraging OS in children with diffuse intrinsic pontine glioma – MedPage Today (free registration required)
Joint final report of Phase III trials demonstrate positive outcomes from combination of PCV chemotherapy and RT in patients with anaplastic oligodendroglial tumors.
30 Jun, 2022 | 10:16h | UTC
M-A: Stereotactic radiosurgery vs. whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer.
30 May, 2022 | 10:41h | UTCStereotactic radiosurgery versus whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer: a systematic review and meta-analysis – The Lancet Oncology (link to abstract – $ for full-text)
Cohort Study: Effect of awake craniotomy in glioblastoma in eloquent areas.
23 May, 2022 | 00:40h | UTCEffect of awake craniotomy in glioblastoma in eloquent areas (GLIOMAP): a propensity score-matched analysis of an international, multicentre, cohort study – the Lancet Oncology (link to abstract – $ for full-text)
Commentary: Neurologic and Survival Outcomes After Awake Craniotomy for Glioblastoma – The ASCO Post
Commentary on Twitter
In matched cohort of patients with glioblastoma, awake craniotomy resulted in fewer neurological deficits at 3 mo and 6 mo post-surgery than asleep resection, and longer mOS (17.0 mo versus 14.0 mo; P =0.0005), and mPFS (9.0 mo versus 7.3 mo; P = 0.006) https://t.co/S1fdRTxYDg
— NatureRevClinOncol (@NatRevClinOncol) May 19, 2022
RCT: Treatment with Etirinotecan pegol for patients with metastatic breast cancer and brain metastases.
13 May, 2022 | 10:51h | UTCTreatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases: Final Results From the Phase 3 ATTAIN Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Commentary on Twitter
Treatment with etirinotecan pegol showed no statistically significant improvement in survival among patients with #BreastCancer & brain metastases, but study represents larged published study for this understudied population. https://t.co/AVKeo1BWQV #BCSM #BTSM
— JAMA Oncology (@JAMAOnc) May 12, 2022
ASTRO Guideline: Radiation therapy for brain metastases.
12 May, 2022 | 10:11h | UTCNews Release: ASTRO issues clinical guideline on radiation therapy for brain metastases – American Society for Radiation Oncology
Commentary on Twitter
ASTRO has released a guideline on #RadiationTherapy for brain metastases, which updates the original 2012 guideline. The publication in #PracticalRO includes treatment algorithms for limited & extensive brain metastases. Read here: https://t.co/5QRI0XqWHx #RadOnc pic.twitter.com/oNj2nzAKdm
— ASTRO (@ASTRO_org) May 10, 2022
Study finds no increased risk of brain tumors for mobile phone users.
1 Apr, 2022 | 10:04h | UTCNews Release: No increased risk of brain tumours for mobile phone users, new study finds – University of Oxford
Original Study: Cellular Telephone Use and the Risk of Brain Tumors: Update of the UK Million Women Study – JNCI: Journal of the National Cancer Institute
SEOM-GEINO clinical guideline of systemic therapy and management of brain central nervous system metastases.
18 Mar, 2022 | 08:14h | UTC
Same-day discharge after brain tumor resection: a prospective pilot study.
9 Mar, 2022 | 08:19h | UTC
Commentary on Twitter
In select patients, same day discharge after #brainsurgery can be safe and effective, leading to improved patient feeling of wellness and satisfaction. #brain #cancer #costs @NSTumorSection https://t.co/TSGXcx9dmn pic.twitter.com/VVxuSiGTUX
— Journal of Neuro-Oncology (@JNeurooncol) March 2, 2022
Systematic Review: Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma.
8 Mar, 2022 | 08:24h | UTC
ASCO-SNO Guideline: Therapy for diffuse astrocytic and oligodendroglial tumors in adults.
26 Jan, 2022 | 01:19h | UTC
Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.
21 Jan, 2022 | 09:36h | UTCTreatment for Brain Metastases: ASCO-SNO-ASTRO Guideline – Journal of Clinical Oncology
Long-term outcomes of patients with active melanoma brain metastases treated with combination nivolumab plus ipilimumab.
16 Nov, 2021 | 08:14h | UTCLong-term outcomes of patients with active melanoma brain metastases treated with combination nivolumab plus ipilimumab (CheckMate 204): final results of an open-label, multicentre, phase 2 study – The Lancet Oncology (link to abstract – $ for full-text)
Original Study: Study: Combination Immunotherapy for Melanoma Brain Metastases
M-A: Treatment options for progression or recurrence of glioblastoma.
26 Sep, 2021 | 21:34h | UTCSummary: Treatment options for people with recurrent and progressive glioblastoma – Cochrane Library
Brain and other central nervous system tumor statistics, 2021 – There were few improvements in the care of Glioblastoma in the past 4 decades. Specifically, the 5-year survival only increased from 4% to 7%.
1 Sep, 2021 | 08:58h | UTCBrain and other central nervous system tumor statistics, 2021 – CA: A Cancer Journal for Clinicians
Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer – “This trial provides the first clinical evidence that sparing the hippocampus during PCI in patients with SCLC better preserves cognitive function”.
13 Aug, 2021 | 08:54h | UTC
EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumors.
11 Aug, 2021 | 08:29h | UTCCommentary: New guidelines for the diagnosis and treatment of brain metastases – University of Vienna
Commentary on Twitter
Just out📣 @EANOassociation-ESMO Guidelines for the management of patients with #brain metastasis from solid #tumours: find out the latest recommendations, immunohistochemical markers for #carcinoma of unknown primary and treatment algorithms 🔎 https://t.co/CriaZKxFJr #btsm pic.twitter.com/0yQqmJMzT1
— ESMO – Eur. Oncology (@myESMO) August 5, 2021
Diagnosing and treating brain tumors: reflections on the latest Cochrane evidence
19 Mar, 2021 | 08:06h | UTC
Guidelines in the management of CNS tumors
23 Feb, 2021 | 01:09h | UTCGuidelines in the management of CNS tumors – Journal of Neuro-Oncology
Intraoperative imaging technology to maximize extent of resection for glioma: a network meta‐analysis
8 Feb, 2021 | 20:11h | UTC