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Oncology – Brain

M-A | Extent of tumor resection and survival in pediatric patients with high-grade gliomas.

17 Aug, 2022 | 14:00h | UTC

Extent of Tumor Resection and Survival in Pediatric Patients With High-Grade Gliomas: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


ASTRO Guideline | Radiation therapy for IDH-mutant grade 2 and grade 3 diffuse glioma.

29 Jul, 2022 | 12:33h | UTC

Radiation Therapy for IDH-Mutant Grade 2 and Grade 3 Diffuse Glioma: An ASTRO Clinical Practice Guideline – Practical Radiation Oncology

 


Single-arm study | Intensive multimodality therapy for extraocular retinoblastoma.

21 Jul, 2022 | 12:25h | UTC

Intensive Multimodality Therapy for Extraocular Retinoblastoma: A Children’s Oncology Group Trial (ARET0321) – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


The Global Retinoblastoma Outcome Study | A prospective, cluster-based analysis of 4,064 patients from 149 countries.

14 Jul, 2022 | 12:16h | UTC

The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries – The Lancet Global Health

Invited Commentary: Retinoblastoma as a lens for correctable disparities worldwide – The Lancet Global Health

News Release: Children in low-income countries 16 times more likely to die from most common eye cancer – London School of Hygiene & Tropical Medicine

 


Phase II RCT | Proton craniospinal irradiation vs. photon involved-field radiotherapy for patients with solid tumor leptomeningeal metastasis.

13 Jul, 2022 | 11:09h | UTC

Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


Phase 1 single-arm study | Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma.

4 Jul, 2022 | 12:08h | UTC

Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Oncolytic Virus Infusion Promising as Brain-Stem Glioma Treatment — Phase I trial shows encouraging OS in children with diffuse intrinsic pontine glioma – MedPage Today (free registration required)


Joint final report of Phase III trials demonstrate positive outcomes from combination of PCV chemotherapy and RT in patients with anaplastic oligodendroglial tumors.

30 Jun, 2022 | 10:16h | UTC

News Release: Joint final report of Phase III trials demonstrate positive outcomes from combination of PCV chemotherapy and RT in patients with anaplastic oligodendroglial tumors – NPR Oncology

Original Study: Joint Final Report of EORTC 26951 and RTOG 9402: Phase III Trials With Procarbazine, Lomustine, and Vincristine Chemotherapy for Anaplastic Oligodendroglial Tumors – Journal of Clinical Oncology

 


M-A: Stereotactic radiosurgery vs. whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer.

30 May, 2022 | 10:41h | UTC

Stereotactic radiosurgery versus whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer: a systematic review and meta-analysis – The Lancet Oncology (link to abstract – $ for full-text)

News Release: Meta-Analysis Shows Targeted Radiation Therapy May Be as Effective as Standard Care for Small Cell Lung Cancer Patients with Brain Metastases – St. Michael’s Hospital

 


Cohort Study: Effect of awake craniotomy in glioblastoma in eloquent areas.

23 May, 2022 | 00:40h | UTC

Effect of awake craniotomy in glioblastoma in eloquent areas (GLIOMAP): a propensity score-matched analysis of an international, multicentre, cohort study – the Lancet Oncology (link to abstract – $ for full-text)

Commentary: Neurologic and Survival Outcomes After Awake Craniotomy for Glioblastoma – The ASCO Post

 

Commentary on Twitter

 


RCT: Treatment with Etirinotecan pegol for patients with metastatic breast cancer and brain metastases.

13 May, 2022 | 10:51h | UTC

Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases: Final Results From the Phase 3 ATTAIN Randomized Clinical Trial – JAMA Oncology (free for a limited period)

 

Commentary on Twitter

 


ASTRO Guideline: Radiation therapy for brain metastases.

12 May, 2022 | 10:11h | UTC

Radiation Therapy for Brain Metastases: An ASTRO Clinical Practice Guideline – Practical Radiation Oncology

News Release: ASTRO issues clinical guideline on radiation therapy for brain metastases – American Society for Radiation Oncology

 

Commentary on Twitter

 


Study finds no increased risk of brain tumors for mobile phone users.

1 Apr, 2022 | 10:04h | UTC

News Release: No increased risk of brain tumours for mobile phone users, new study finds – University of Oxford

Original Study: Cellular Telephone Use and the Risk of Brain Tumors: Update of the UK Million Women Study – JNCI: Journal of the National Cancer Institute

 


SEOM-GEINO clinical guideline of systemic therapy and management of brain central nervous system metastases.

18 Mar, 2022 | 08:14h | UTC

SEOM-GEINO clinical guideline of systemic therapy and management of brain central nervous system metastases (2021) – Clinical and Translational Oncology

 


Same-day discharge after brain tumor resection: a prospective pilot study.

9 Mar, 2022 | 08:19h | UTC

Same-day discharge after brain tumor resection: a prospective pilot study – Journal of Neuro-Oncology

 

Commentary on Twitter

 


Systematic Review: Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma.

8 Mar, 2022 | 08:24h | UTC

Diagnostic test accuracy and cost‐effectiveness of tests for codeletion of chromosomal arms 1p and 19q in people with glioma – Cochrane Library

 


ASCO-SNO Guideline: Therapy for diffuse astrocytic and oligodendroglial tumors in adults.

26 Jan, 2022 | 01:19h | UTC

Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline – Journal of Clinical Oncology

 


Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.

21 Jan, 2022 | 09:36h | UTC

Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline – Journal of Clinical Oncology

Related: EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumors.

 


Long-term outcomes of patients with active melanoma brain metastases treated with combination nivolumab plus ipilimumab.

16 Nov, 2021 | 08:14h | UTC

Long-term outcomes of patients with active melanoma brain metastases treated with combination nivolumab plus ipilimumab (CheckMate 204): final results of an open-label, multicentre, phase 2 study – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Combination immunotherapy improves survival for patients with asymptomatic melanoma brain metastases – The University of Texas MD Anderson Cancer Center

Original Study: Study: Combination Immunotherapy for Melanoma Brain Metastases

Related: #ESMO19 – Randomized Trial: Improved Overall Survival at 5 Years with Combined Immunotherapy for Advanced Melanoma

 


M-A: Treatment options for progression or recurrence of glioblastoma.

26 Sep, 2021 | 21:34h | UTC

Treatment options for progression or recurrence of glioblastoma: a network meta‐analysis – Cochrane Library

Summary: Treatment options for people with recurrent and progressive glioblastoma – Cochrane Library

 


Brain and other central nervous system tumor statistics, 2021 – There were few improvements in the care of Glioblastoma in the past 4 decades. Specifically, the 5-year survival only increased from 4% to 7%.

1 Sep, 2021 | 08:58h | UTC

Brain and other central nervous system tumor statistics, 2021 – CA: A Cancer Journal for Clinicians

 


Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer – “This trial provides the first clinical evidence that sparing the hippocampus during PCI in patients with SCLC better preserves cognitive function”.

13 Aug, 2021 | 08:54h | UTC

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study – Journal of Clinical Oncology

 


EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumors.

11 Aug, 2021 | 08:29h | UTC

EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours – Annals of Oncology

Commentary: New guidelines for the diagnosis and treatment of brain metastases – University of Vienna

 

Commentary on Twitter

 


Diagnosing and treating brain tumors: reflections on the latest Cochrane evidence

19 Mar, 2021 | 08:06h | UTC

Diagnosing and treating brain tumours: reflections on the latest Cochrane evidence – Evidently Cochrane

 


Guidelines in the management of CNS tumors

23 Feb, 2021 | 01:09h | UTC

Guidelines in the management of CNS tumors – Journal of Neuro-Oncology

 


Intraoperative imaging technology to maximize extent of resection for glioma: a network meta‐analysis

8 Feb, 2021 | 20:11h | UTC

Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis – Cochrane Library

 


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