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Pharmacology

[Preprint] Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19: An international collaborative meta-analysis of randomized trials

20 Sep, 2020 | 21:42h | UTC

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19: an international collaborative meta-analysis of randomized trials – medRxiv

 

Commentary on Twitter

 


Who gets a COVID vaccine first? Access plans are taking shape

20 Sep, 2020 | 21:24h | UTC

Who gets a COVID vaccine first? Access plans are taking shape – Nature

Related: WHO Guidance: Allocation and prioritization of COVID-19 vaccination

 

Commentary on Twitter

 


[Abstract Only] Survival with Olaparib in metastatic castration-resistant prostate cancer

20 Sep, 2020 | 21:13h | UTC

Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer – New England Journal of Medicine

 

Commentary on Twitter

 


[Abstract Only] Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma

20 Sep, 2020 | 21:11h | UTC

Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma – New England Journal of Medicine

 

Commentary on Twitter

 

 


Two pharma companies released their coronavirus vaccine blueprints in a bid to regain public trust

18 Sep, 2020 | 09:30h | UTC

Two Pharma Companies Released Their Coronavirus Vaccine Blueprints In A Bid To Regain Public Trust – BuzzFeed

 


Study: Longer-than-necessary duration of outpatient antibiotic therapy for common outpatient infections

18 Sep, 2020 | 09:21h | UTC

Duration of outpatient antibiotic therapy for common outpatient infections – Clinical Infectious Diseases

 

Commentary on Twitter

 


Antimicrobial resistance: The next big pandemic?

18 Sep, 2020 | 09:19h | UTC

Antimicrobial resistance: The next big pandemic? – Open Access Government

 


WHO Guidance: Allocation and prioritization of COVID-19 vaccination

17 Sep, 2020 | 09:42h | UTC

WHO SAGE values framework for the allocation and prioritization of COVID-19 vaccination – World Health Organization

Commentary: World Health Organization announces distribution plan for COVID-19 vaccine – ABD News

Related: An ethical framework for global vaccine allocation – Science

 


[Press release – not published yet] Eli Lilly reports first, promising results for an antibody against COVID-19

17 Sep, 2020 | 09:28h | UTC

Eli Lilly reports first, promising results for an antibody against COVID-19 – Science

Press release: Lilly announces proof of concept data for neutralizing antibody LY-CoV555 in the COVID-19 outpatient setting

 


[Abstract Only] Two-year, randomized, controlled trial of belimumab in lupus nephritis

17 Sep, 2020 | 09:20h | UTC

Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis – New England Journal of Medicine (link to abstract – $ for full-text)

 


Lifelong aspirin for all in the secondary prevention of chronic coronary syndrome: Still sacrosanct or is reappraisal warranted?

17 Sep, 2020 | 09:19h | UTC

Lifelong Aspirin for All in the Secondary Prevention of Chronic Coronary Syndrome: Still Sacrosanct or is Reappraisal Warranted? – Circulation (free for a limited period)

 


Perspective: Up is down — pharmaceutical industry caution vs. federal acceleration of Covid-19 vaccine approval

16 Sep, 2020 | 09:06h | UTC

Up Is Down — Pharmaceutical Industry Caution vs. Federal Acceleration of Covid-19 Vaccine Approval – New England Journal of Medicine

 


UK tests if COVID-19 vaccines might work better inhaled

16 Sep, 2020 | 08:56h | UTC

UK tests if COVID-19 vaccines might work better inhaled – Associated Press

 


Coronavirus: Monoclonal antibodies to begin UK trial

16 Sep, 2020 | 08:53h | UTC

Coronavirus: Monoclonal antibodies to begin UK trial – BBC

See also: Covid-19: RECOVERY trial will evaluate “antiviral antibody cocktail” – The BMJ

 


AHA Scientific Statement: Drug-induced arrhythmias

16 Sep, 2020 | 08:50h | UTC

Drug-Induced Arrhythmias: A Scientific Statement From the American Heart Association – Circulation

Commentary: Drug Proarrhythmia

Top Things to Know: Drug-Induced Arrhythmias

News Release: Identifying, preventing and managing heart rhythm side effects of medicines

 


NIH launches two trials to test blood thinners in COVID-19 patients

15 Sep, 2020 | 08:56h | UTC

NIH launches two trials to test blood thinners in COVID-19 patients – Reuters

 


Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency

15 Sep, 2020 | 08:53h | UTC

Scientists relieved as coronavirus vaccine trial restarts — but question lack of transparency – Nature

 


Perspective: Vaccine transparency

15 Sep, 2020 | 08:48h | UTC

Vaccine Transparency – Science Translational Medicine

 


Coronavirus: Who would get the vaccine first?

15 Sep, 2020 | 08:47h | UTC

Coronavirus: Who would get the vaccine first? – BBC

 


[Abstract Only] Preliminary trial on the effectiveness of Curcuma longa extract for the treatment of knee osteoarthritis

15 Sep, 2020 | 08:38h | UTC

Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee Osteoarthritis: A Randomized Trial – Annals of Internal Medicine

Commentaries: Turmeric May Help Relieve Pain from Knee Osteoarthritis – NEJM Journal Watch

 


Largest global vaccine confidence survey reveals hesitancy hotspots

14 Sep, 2020 | 01:16h | UTC

Largest global vaccine confidence survey reveals hesitancy hotspots – London School of Hygiene & Tropical Medicine

Original Study: Mapping global trends in vaccine confidence and investigating barriers to vaccine uptake: a large-scale retrospective temporal modelling study – The Lancet

The Lancet Infographics: How global perceptions of vaccines have changed

 

Commentary on Twitter

 


Updated meta-analysis: Drug treatments for Covid-19

14 Sep, 2020 | 01:04h | UTC

Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ

 

Commentary on Twitter

 


A COVID-19 vaccine may be only 50% effective. Is that good enough?

14 Sep, 2020 | 01:03h | UTC

A COVID-19 Vaccine May Be Only 50% Effective. Is That Good Enough? – NPR

 


AstraZeneca resumes Covid-19 vaccine trials in the U.K.

14 Sep, 2020 | 01:01h | UTC

AstraZeneca resumes Covid-19 vaccine trials in the U.K. – STAT

See also: The ethics of pausing a vaccine trial in the midst of a pandemic: a conversation with Ruth Faden  – STAT AND University of Oxford resumes vaccine trial

 


[Abstract Only] Randomized trial: Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy

14 Sep, 2020 | 00:58h | UTC

Valaciclovir to prevent vertical transmission of cytomegalovirus after maternal primary infection during pregnancy: a randomised, double-blind, placebo-controlled trial – The Lancet

 


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