Nutrition Therapy in the Hospital
M-A | Optimizing enteral nutrition delivery by implementing volume-based feeding protocol for critically ill patients
24 May, 2023 | 13:13h | UTC
M-A | Prevalence and outcomes of frailty in unplanned hospital admissions
9 May, 2023 | 14:45h | UTC
Review | What the clinician needs to know about medical nutrition therapy in critically ill patients in 2023
26 Apr, 2023 | 13:59h | UTC
Review | Refeeding Syndrome: diagnostic challenges and the potential of clinical decision support systems
10 Apr, 2023 | 13:28h | UTC
RCT | Low-calorie, low-protein feeding improves recovery time in ventilated adults with shock
22 Mar, 2023 | 13:42h | UTCSummary: The NUTRIREA-3 study aimed to determine the optimal calorie and protein intakes during the acute phase of severe critical illness. The study was a randomized, controlled, multicenter, open-label, parallel-group trial conducted in 61 French intensive care units (ICUs) involving 3044 adults receiving invasive mechanical ventilation and vasopressor support for shock. During the first seven ICU days, participants were randomly assigned to early nutrition with either low or standard calorie and protein targets. The primary endpoints were time to readiness for ICU discharge and day 90 all-cause mortality, while key secondary outcomes included secondary infections, gastrointestinal events, and liver dysfunction.
The study found that early calorie and protein restriction did not decrease mortality. However, it was associated with faster recovery and fewer complications compared to standard calorie and protein targets. The low-calorie, low-protein group had a shorter median time to readiness for ICU discharge and lower proportions of patients with vomiting, diarrhea, bowel ischemia, and liver dysfunction. The proportions of patients with secondary infections did not differ significantly between the two groups.
In conclusion, the NUTRIREA-3 study provides evidence that patients may benefit from restricted calorie and protein intakes during the acute phase of critical illness, as it expedites recovery and reduces the risk of complications.
Article: Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3) – The Lancet Respiratory Medicine (free registration required)
Commentary on Twitter
NEW Research—Early calorie & protein restriction did not decrease mortality but was associated w/ faster recovery & fewer complications than standard intake targets
NUTRIREA-3 from Prof Jean Reignier & co https://t.co/VCS72qxLPD
Being presented @ISICEM today! #ISICEM23 pic.twitter.com/TpoJnwHP8P
— The Lancet Respiratory Medicine (@LancetRespirMed) March 21, 2023
Review | Nutritional management of the infant with chronic kidney disease stages 2–5 and on dialysis
9 Mar, 2023 | 14:18h | UTC
RCT | Caffeine did not reduce time to first bowel movement after laparoscopic colectomy
1 Mar, 2023 | 13:41h | UTCCaffeine for intestinal transit after laparoscopic colectomy: randomized clinical trial (CaCo trial) – British Journal of Surgery (link to abstract – $ for full-text)
Commentary on Twitter
In BJS' December issue: Caffeine for intestinal transit after laparoscopic colectomy: randomized clinical trial (CaCo trial) https://t.co/6z1cboAxi0 @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @paulo_sutt @robhinchliffe1 @young_bjs pic.twitter.com/yGtXiIwgq0
— BJS (@BJSurgery) December 28, 2022
Review | (Mal)nutrition in critical illness and beyond
28 Feb, 2023 | 13:28h | UTC(Mal)nutrition in critical illness and beyond: a narrative review – Anaesthesia
ESPEN practical guideline | Home parenteral nutrition
20 Feb, 2023 | 12:21h | UTCSummary: Home parenteral nutrition (HPN) is a form of nutrition support where a patient receives intravenous nutrition at home. It is used for patients who cannot receive adequate nutrition through oral or enteral routes, such as those with intestinal failure, severe inflammatory bowel disease, or other gastrointestinal disorders. HPN can be a life-saving therapy, but it requires careful patient selection, as well as ongoing monitoring and management by a multidisciplinary team. The ESPEN guideline aims to provide practical guidance on the use of HPN, including the nutritional and metabolic aspects of care and the practical considerations of administering HPN at home. The guideline also emphasizes the importance of patient-centered care and shared decision-making, highlighting the need for regular assessment and monitoring of patients.
Article: ESPEN practical guideline: Home parenteral nutrition – Clinical Nutrition
M-A | The rate and assessment of muscle wasting during critical illness
17 Feb, 2023 | 12:55h | UTC
Commentary on Twitter
A Review published in @Crit_Care analyzes the data of ICU muscle wasting studies and reports that critically ill patients lose nearly 2% of skeletal muscle per day during the first week of ICU admission.https://t.co/qW5jzbWRSk
— BMC (@BioMedCentral) January 8, 2023
Review | Preoperative frailty screening, assessment and management
16 Feb, 2023 | 14:37h | UTCPreoperative frailty screening, assessment and management – Current Opinion in Anaesthesiology
Position Paper | Enteral nutrition in preterm infants
30 Jan, 2023 | 00:54h | UTC
Toward nutrition improving outcome of critically ill patients: how to interpret recent feeding RCTs?
30 Jan, 2023 | 00:42h | UTC
RCT | Higher protein dosing did not improve outcomes in critically ill patients with high nutritional risk
27 Jan, 2023 | 12:24h | UTCThe effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Researchers aimed to test the hypothesis that a higher dose of protein provided to critically ill patients would improve clinical outcomes.
Here's what they found 🧵 /4 https://t.co/C5JswTr82o
— The Lancet (@TheLancet) January 26, 2023
RCT | Continued enteral nutrition until extubation was noninferior to a 6-h fasting strategy before extubation in patients in the ICU
26 Jan, 2023 | 12:49h | UTCContinued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial – The Lancet Respiratory Medicine (free registration required)
Invited Commentary: Continuation of enteral nutrition until extubation in critically ill patients – The Lancet Respiratory Medicine
Commentary on Twitter
NEW Research—Continued enteral nutrition until extubation in critically ill patients in the ICU is a practice that could be safe to implement and be associated with potential benefits
Read the trial from Mickaël Landais & colleagues here: https://t.co/iAvet2DNjN #SCCM2023 pic.twitter.com/SBal9qkAyQ
— The Lancet Respiratory Medicine (@LancetRespirMed) January 21, 2023
Evidence-Based Guidance | Medical nutrition therapy in ECMO patients
26 Jan, 2023 | 12:28h | UTC
RCT | In patients undergoing cardiac surgery, intravenous high-dose selenium did not reduce morbidity or mortality
15 Jan, 2023 | 20:00h | UTC
Commentary on Twitter
In this study, high-dose sodium selenite was not effective in reducing the development of organ dysfunction and death in high-risk cardiac surgery patients. @CStoppe @CriticalCa https://t.co/H3HR1u1HhU
— JAMA Surgery (@JAMASurgery) January 12, 2023
Review | Intermittent feeding and circadian rhythm in critical illness.
12 Dec, 2022 | 12:20h | UTCIntermittent feeding and circadian rhythm in critical illness – Current Opinion in Critical Care
Review | The role of nutrition rehabilitation in the recovery of survivors of critical illness.
6 Dec, 2022 | 13:34h | UTC
M-A | Comparison of continuous versus intermittent enteral feeding in critically ill patients.
31 Oct, 2022 | 13:48h | UTC
Nutrition assessment and management in patients with cirrhosis and cognitive impairment: a comprehensive review of literature.
19 Sep, 2022 | 12:29h | UTCCommentary: Review Outlines Nutrition Assessment, Management in Patients With Cirrhosis – AJMC
RCT | In patients with severe burns, supplemental glutamine did not improve outcomes.
11 Sep, 2022 | 22:59h | UTCA Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
RE-ENERGIZE Study: In this trial involving critically ill patients with burn injuries, enteral glutamine supplementation did not reduce the time to discharge alive from the hospital. @DarenHeyland #europeanburnsassociation #eba #burns https://t.co/f69MDVmsNv pic.twitter.com/fMWr675aCJ
— NEJM (@NEJM) September 9, 2022
Casting light on the necessary, expansive, and evolving role of the critical care dietitian: an essential member of the critical care team.
8 Sep, 2022 | 14:39h | UTCCasting Light on the Necessary, Expansive, and Evolving Role of the Critical Care Dietitian: An Essential Member of the Critical Care Team – Critical Care Medicine (free for a limited period)
Commentary on Twitter
Patel et al: #ICUdietician valuable shared resource w' evolving & expanding need in #CritCareMed
🍱Expert perspectives #ICUnutrition
Link: https://t.co/OyEQSQdJde@SCCM @PedCritCareMed @CritCareExplore pic.twitter.com/mt7Z9lf2WZ
— Critical Care Medicine (@CritCareMed) August 31, 2022
M-A | Probiotics in critical illness.
1 Aug, 2022 | 12:28h | UTCProbiotics in Critical Illness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Critical Care Medicine (free for a limited period)
Commentary on Twitter
#OpenAccess #VisualAbstract @SameerSharifMD et al: Sys Review & MA of #Probiotics in #CritCareMed
67 RCTs 8483 pts
⬇️VAP HAP #ICULOS, #mechvent
No effect on mortality
Low certainty evidenceLink: https://t.co/kN7FliTpbr@SCCM #CritCareMed @Bram_Rochwerg @leashgreer pic.twitter.com/pROjhq9T2J
— Critical Care Medicine (@CritCareMed) July 22, 2022
Consensus Recommendations | Screening, diagnosis and management of sarcopenia and frailty in hospitalized older adults.
21 Jul, 2022 | 13:08h | UTC