Pain Medicine | Links Medicus Content Curation & Alerts in Medicine

M-A | Types and concentrations of blood-based biomarkers in adults with peripheral neuropathies

3 Feb, 2023 | 13:49h | UTC

Types and Concentrations of Blood-Based Biomarkers in Adults With Peripheral Neuropathies: A Systematic Review and Meta-analysis – JAMA Network Open

Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews

2 Feb, 2023 | 15:05h | UTC

Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews – The BMJ

Editorial: Rethinking use of medicines for chronic pain – The BMJ

News Release: Antidepressants use for chronic pain on the rise, but are they effective? – University of Sidney

Commentary from the author on Twitter (thread – click for more)

Out today in @bmj_latest

We reviewed the evidence on the efficacy of antidepressants for pain in adults

We showed that antidepressants are effective for some pain conditions, but for most they are either ineffective or evidence is inconclusivehttps://t.co/E2XVQ9oGUQ
🧵 pic.twitter.com/kBo7eAyeCP

— Giovanni Ferreira (@giovanni_ef) February 1, 2023

Complex regional pain syndrome: practical diagnostic and treatment guidelines

2 Feb, 2023 | 14:54h | UTC

Complex Regional Pain Syndrome: Practical Diagnostic and Treatment Guidelines, 5th Edition – Pain Medicine

RCT | Diclofenac diethylamine 2.32% gel applied twice daily vs. 1.16% gel four times daily in patients with acute ankle sprain

2 Feb, 2023 | 14:49h | UTC

Randomized, double-blind, noninferiority study of diclofenac diethylamine 2.32% gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily in patients with acute ankle sprain – BMC Musculoskeletal Disorders

Review | Diagnosis and acute management of migraine

31 Jan, 2023 | 14:04h | UTC

Diagnosis and acute management of migraine – Canadian Medical Association Journal

News Release: Migraine: how to diagnose, manage and prevent – Canadian Medical Association Journal

Preliminary study suggests decompression surgery may improve symptoms in neurogenic thoracic outlet syndrome

26 Jan, 2023 | 12:23h | UTC

Surgery Versus Continued Conservative Treatment for Neurogenic Thoracic Outlet Syndrome: the First Randomised Clinical Trial (STOPNTOS Trial) – European Journal of Vascular and Endovascular Surgery

Neurogenic thoracic outlet syndrome: presentation, diagnosis, and treatment

26 Jan, 2023 | 12:22h | UTC

Neurogenic Thoracic Outlet Syndrome: Presentation, diagnosis, and treatment – Deutsches Ärzteblatt international

RCT | Oral ibuprofen and oral ketorolac are similarly effective for children with acute traumatic pain

20 Jan, 2023 | 14:47h | UTC

Oral ibuprofen versus oral ketorolac for children with moderate and severe acute traumatic pain: a randomized comparative study – European Journal of Pediatrics

RCT | Bilateral ultrasound-guided erector spinae plane block vs. wound infiltration for postoperative analgesia in lumbar spinal fusion surgery

20 Jan, 2023 | 14:18h | UTC

Bilateral ultrasound-guided erector spinae plane block versus wound infiltration for postoperative analgesia in lumbar spinal fusion surgery: a randomized controlled trial – European Spine Journal

Commentary: Bilateral USG-guided ESP block decreases short-term opioid consumption after lumbar spinal fusion surgery – Medical Dialogues

RCT | Ultrasound-guided percutaneous cryoneurolysis to treat chronic postamputation phantom limb pain

17 Jan, 2023 | 13:13h | UTC

Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial – Anesthesiology

RCT | Effect of a biopsychosocial intervention vs. postural therapy in patients with acute and subacute spine pain

12 Jan, 2023 | 13:15h | UTC

Effect of a Biopsychosocial Intervention or Postural Therapy on Disability and Health Care Spending Among Patients With Acute and Subacute Spine Pain: The SPINE CARE Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

RCT | Effect of prescriber notifications of patient’s fatal overdose on opioid prescribing at 4 to 12 months

10 Jan, 2023 | 14:50h | UTC

Effect of Prescriber Notifications of Patient’s Fatal Overdose on Opioid Prescribing at 4 to 12 Months: A Randomized Clinical Trial – JAMA Network Open

News Release: Study suggests one solution to America’s opioid epidemic: Tell doctors their patients fatally overdosed – University of Southern California

Commentary on Twitter

Letters notifying clinicians of a patient's fatal overdose reduced opioid prescribing up to one year after receiving the letter. https://t.co/cEU1inH9lE

— JAMA Network Open (@JAMANetworkOpen) January 6, 2023

Review | Management of chronic migraine.

15 Dec, 2022 | 13:41h | UTC

Management of chronic migraine – The BMJ

RCT | Comparing bupivacaine alone to liposomal bupivacaine plus bupivacaine in interscalene blocks for total shoulder arthroplasty.

15 Dec, 2022 | 13:36h | UTC

Comparing bupivacaine alone to liposomal bupivacaine plus bupivacaine in interscalene blocks for total shoulder arthroplasty: a randomized, non-inferiority trial – Regional Anesthesia & Pain Medicine

RCT | US-guided pudendal nerve block vs. US-guided penile nerve block for analgesia during pediatric circumcision.

15 Dec, 2022 | 13:31h | UTC

Randomized controlled trial (RCT) comparing ultrasound-guided pudendal nerve block with ultrasound-guided penile nerve block for analgesia during pediatric circumcision – Regional Anesthesia & Pain Medicine (link to abstract – $ for full-text)

RCT | Medication optimization vs. cognitive behavioral therapy in patients with chronic low back pain.

14 Dec, 2022 | 14:58h | UTC

Effect of Medication Optimization vs Cognitive Behavioral Therapy Among US Veterans With Chronic Low Back Pain Receiving Long-term Opioid Therapy: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

RCT of Veterans w/chronic low back pain prescribed opioids found collaborative care medication optimization was modestly more effective in reducing pain at 1 year, compared to individual psychologist-delivered cognitive behavioral therapy. @DrMikeBushey https://t.co/K0kXy5Ngou

— JAMA Network Open (@JAMANetworkOpen) November 17, 2022

SR | Use of acupuncture for adult health conditions, 2013 to 2021.

14 Dec, 2022 | 14:54h | UTC

Use of Acupuncture for Adult Health Conditions, 2013 to 2021: A Systematic Review – JAMA Network Open

RCT | Ropivacaine perineal infiltration after episiotomy did not reduce postpartum pain.

13 Dec, 2022 | 14:16h | UTC

Ropivacaine perineal infiltration for postpartum pain management in episiotomy repair: a double-blind, randomised, placebo-controlled trial – BJOG (link to abstract – $ for full-text)

SR | Global prevalence and incidence of shoulder pain.

13 Dec, 2022 | 14:09h | UTC

A systematic review of the global prevalence and incidence of shoulder pain – BMC Musculoskeletal Disorders

ASCO Guideline | Use of opioids for adults with pain from cancer or cancer treatment.

7 Dec, 2022 | 14:32h | UTC

Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline – Journal of Clinical Oncology

Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

M-A | Placebo response and media attention in randomized clinical trials assessing cannabis-based therapies for pain.

1 Dec, 2022 | 14:06h | UTC

Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis – JAMA Network Open

News Release: Positive media coverage of cannabis studies regardless of therapeutic effect – Karolinska Institutet

Commentaries:

Cannabis is no better than a placebo for treating pain – new research – The Conversation

Media Coverage, Placebo Response Linked to Pain Relief Seen in Cannabinoid Trials – Psychiatric News Alert

Commentary on Twitter

Cannabinoid clinical trials for pain generate relatively high media attention despite low effect sizes, which may help shape placebo responses in subsequent trials. https://t.co/sINTpeGeMO

— JAMA Network Open (@JAMANetworkOpen) November 28, 2022