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Pain Medicine

M-A | Types and concentrations of blood-based biomarkers in adults with peripheral neuropathies

3 Feb, 2023 | 13:49h | UTC

Types and Concentrations of Blood-Based Biomarkers in Adults With Peripheral Neuropathies: A Systematic Review and Meta-analysis – JAMA Network Open

 


Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews

2 Feb, 2023 | 15:05h | UTC

Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews – The BMJ

Editorial: Rethinking use of medicines for chronic pain – The BMJ

News Release: Antidepressants use for chronic pain on the rise, but are they effective? – University of Sidney

 

Commentary from the author on Twitter (thread – click for more)

 


Complex regional pain syndrome: practical diagnostic and treatment guidelines

2 Feb, 2023 | 14:54h | UTC

Complex Regional Pain Syndrome: Practical Diagnostic and Treatment Guidelines, 5th Edition – Pain Medicine

Related: Complex Regional Pain Syndrome: A Comprehensive Review – Pain and Therapy

 


RCT | Diclofenac diethylamine 2.32% gel applied twice daily vs. 1.16% gel four times daily in patients with acute ankle sprain

2 Feb, 2023 | 14:49h | UTC

Randomized, double-blind, noninferiority study of diclofenac diethylamine 2.32% gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily in patients with acute ankle sprain – BMC Musculoskeletal Disorders

 


Review | Diagnosis and acute management of migraine

31 Jan, 2023 | 14:04h | UTC

Diagnosis and acute management of migraine – Canadian Medical Association Journal

News Release: Migraine: how to diagnose, manage and prevent – Canadian Medical Association Journal

 


Preliminary study suggests decompression surgery may improve symptoms in neurogenic thoracic outlet syndrome

26 Jan, 2023 | 12:23h | UTC

Surgery Versus Continued Conservative Treatment for Neurogenic Thoracic Outlet Syndrome: the First Randomised Clinical Trial (STOPNTOS Trial) – European Journal of Vascular and Endovascular Surgery

Related: Neurogenic Thoracic Outlet Syndrome: Presentation, diagnosis, and treatment – Deutsches Ärzteblatt international

 


Neurogenic thoracic outlet syndrome: presentation, diagnosis, and treatment

26 Jan, 2023 | 12:22h | UTC

Neurogenic Thoracic Outlet Syndrome: Presentation, diagnosis, and treatment – Deutsches Ärzteblatt international

 


RCT | Oral ibuprofen and oral ketorolac are similarly effective for children with acute traumatic pain

20 Jan, 2023 | 14:47h | UTC

Oral ibuprofen versus oral ketorolac for children with moderate and severe acute traumatic pain: a randomized comparative study – European Journal of Pediatrics

 


RCT | Bilateral ultrasound-guided erector spinae plane block vs. wound infiltration for postoperative analgesia in lumbar spinal fusion surgery

20 Jan, 2023 | 14:18h | UTC

Bilateral ultrasound-guided erector spinae plane block versus wound infiltration for postoperative analgesia in lumbar spinal fusion surgery: a randomized controlled trial – European Spine Journal

Commentary: Bilateral USG-guided ESP block decreases short-term opioid consumption after lumbar spinal fusion surgery – Medical Dialogues

 


RCT | Ultrasound-guided percutaneous cryoneurolysis to treat chronic postamputation phantom limb pain

17 Jan, 2023 | 13:13h | UTC

Ultrasound-guided Percutaneous Cryoneurolysis to Treat Chronic Postamputation Phantom Limb Pain: A Multicenter Randomized Controlled Trial – Anesthesiology

 


RCT | Effect of a biopsychosocial intervention vs. postural therapy in patients with acute and subacute spine pain

12 Jan, 2023 | 13:15h | UTC

Effect of a Biopsychosocial Intervention or Postural Therapy on Disability and Health Care Spending Among Patients With Acute and Subacute Spine Pain: The SPINE CARE Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

See also: Visual Abstract

News Release: Randomized Trial Finds Therapies for Spine Pain Improved Disability and Quality of Life But Did Not Decrease Healthcare Spending – Brigham and Women’s Hospital

Commentary: Noninvasive Interventions Can Reduce Spine Pain Versus Usual Care – HealthDay

 

Commentary on Twitter

 


RCT | Effect of prescriber notifications of patient’s fatal overdose on opioid prescribing at 4 to 12 months

10 Jan, 2023 | 14:50h | UTC

Effect of Prescriber Notifications of Patient’s Fatal Overdose on Opioid Prescribing at 4 to 12 Months: A Randomized Clinical Trial – JAMA Network Open

News Release: Study suggests one solution to America’s opioid epidemic: Tell doctors their patients fatally overdosed – University of Southern California

 

Commentary on Twitter

 


Review | Management of chronic migraine.

15 Dec, 2022 | 13:41h | UTC

Management of chronic migraine – The BMJ

 


RCT | Comparing bupivacaine alone to liposomal bupivacaine plus bupivacaine in interscalene blocks for total shoulder arthroplasty.

15 Dec, 2022 | 13:36h | UTC

Comparing bupivacaine alone to liposomal bupivacaine plus bupivacaine in interscalene blocks for total shoulder arthroplasty: a randomized, non-inferiority trial – Regional Anesthesia & Pain Medicine

 


RCT | US-guided pudendal nerve block vs. US-guided penile nerve block for analgesia during pediatric circumcision.

15 Dec, 2022 | 13:31h | UTC

Randomized controlled trial (RCT) comparing ultrasound-guided pudendal nerve block with ultrasound-guided penile nerve block for analgesia during pediatric circumcision – Regional Anesthesia & Pain Medicine (link to abstract – $ for full-text)

 


RCT | Medication optimization vs. cognitive behavioral therapy in patients with chronic low back pain.

14 Dec, 2022 | 14:58h | UTC

Effect of Medication Optimization vs Cognitive Behavioral Therapy Among US Veterans With Chronic Low Back Pain Receiving Long-term Opioid Therapy: A Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


SR | Use of acupuncture for adult health conditions, 2013 to 2021.

14 Dec, 2022 | 14:54h | UTC

Use of Acupuncture for Adult Health Conditions, 2013 to 2021: A Systematic Review – JAMA Network Open

 


RCT | Ropivacaine perineal infiltration after episiotomy did not reduce postpartum pain.

13 Dec, 2022 | 14:16h | UTC

Ropivacaine perineal infiltration for postpartum pain management in episiotomy repair: a double-blind, randomised, placebo-controlled trial – BJOG (link to abstract – $ for full-text)

 


SR | Global prevalence and incidence of shoulder pain.

13 Dec, 2022 | 14:09h | UTC

A systematic review of the global prevalence and incidence of shoulder pain – BMC Musculoskeletal Disorders

 


ASCO Guideline | Use of opioids for adults with pain from cancer or cancer treatment.

7 Dec, 2022 | 14:32h | UTC

Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline – Journal of Clinical Oncology

 


Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Related:

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults. 

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife. 

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero. 

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

 


M-A | Placebo response and media attention in randomized clinical trials assessing cannabis-based therapies for pain.

1 Dec, 2022 | 14:06h | UTC

Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis – JAMA Network Open

News Release: Positive media coverage of cannabis studies regardless of therapeutic effect – Karolinska Institutet

Commentaries: 

Cannabis is no better than a placebo for treating pain – new research – The Conversation

Media Coverage, Placebo Response Linked to Pain Relief Seen in Cannabinoid Trials – Psychiatric News Alert

 

Commentary on Twitter

 


Review | Pain management strategies in urethral reconstruction.

30 Nov, 2022 | 13:30h | UTC

Pain management strategies in urethral reconstruction: a narrative review – Translational Andrology and Urology

 


Podcast | Opioid use disorder and acute pain in hospitalized patients.

29 Nov, 2022 | 14:05h | UTC

#366 Opioid Use Disorder and Acute Pain in the Hospitalized Patient – The Curbsiders

 


M-A | Acupuncture for low back and/or pelvic pain during pregnancy.

23 Nov, 2022 | 13:52h | UTC

Acupuncture for low back and/or pelvic pain during pregnancy: a systematic review and meta-analysis of randomised controlled trials – BMJ Open

News Release: Acupuncture can relieve lower back/pelvic pain often experienced during pregnancy – BMJ Newsroom

 


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