Head and Neck Surgery
M-A of randomized trials | Prophylactic central neck lymph node dissection in low-risk thyroid carcinoma patients does not decrease the incidence of locoregional recurrence.
21 Sep, 2022 | 13:07h | UTCProphylactic Central Neck Lymph Node Dissection in Low-risk Thyroid Carcinoma Patients Does Not Decrease the Incidence of Locoregional Recurrence: A Meta-analysis of Randomized Trials – Annals of Surgery (link to abstract – $ for full-text)
International consensus statement on obstructive sleep apnea.
8 Sep, 2022 | 14:41h | UTCInternational consensus statement on obstructive sleep apnea – Allergy & Rhinology (PDF)
M-A | Hypocalcemia following thyroidectomy among patients who have previously undergone bariatric surgery.
8 Sep, 2022 | 14:25h | UTCHypocalcaemia following thyroidectomy among patients who have previously undergone bariatric surgery: systematic review and meta-analysis – British Journal of Surgery (link to abstract – $ for full-text)
Guideline | Patient preparation and radiation protection guidance for adult patients undergoing radioiodine treatment for thyroid cancer.
1 Sep, 2022 | 11:53h | UTC
RCT | In patients with low-risk nasopharyngeal carcinoma, radiotherapy alone was noninferior to radiotherapy plus concurrent chemoradiotherapy on survival without disease relapse at 3 years.
25 Aug, 2022 | 12:13h | UTCEffect of Radiotherapy Alone vs Radiotherapy With Concurrent Chemoradiotherapy on Survival Without Disease Relapse in Patients With Low-risk Nasopharyngeal Carcinoma: A Randomized Clinical Trial – JAMA (free for a limited period)
Video Editor’s Note: Radiotherapy With vs Without Chemoradiotherapy in Low-risk Nasopharyngeal Carcinoma – JAMA
The contemporary management of cancers of the sinonasal tract in adults.
16 Aug, 2022 | 13:39h | UTC
Guideline | Pediatric differentiated thyroid carcinoma.
29 Jul, 2022 | 12:31h | UTC
Phase 2 RCT | Deintensified chemoradiotherapy for pretreatment Epstein-Barr Virus DNA-selected low-risk locoregionally advanced nasopharyngeal carcinoma.
19 Jul, 2022 | 12:58h | UTCDeintensified Chemoradiotherapy for Pretreatment Epstein-Barr Virus DNA-Selected Low-Risk Locoregionally Advanced Nasopharyngeal Carcinoma: A Phase II Randomized Noninferiority Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries:
Commentary on Twitter
Less is more? 🤔 2-cycle cisplatin concurrent chemoradiotherapy is not inferior to 3-cycles based on 3-yr PFS in treating locoregionally advanced nasopharyngeal ca w/preRX EBV DNA levels < 4000.QOL & toxicity improved w/ less chemo https://t.co/XovHi2P06W pic.twitter.com/JJqiC8wnWW
— Journal of Clinical Oncology (@JCO_ASCO) January 25, 2022
Evaluation of the molecular landscape of pediatric thyroid nodules and use of a multigene genomic classifier in children.
8 Jul, 2022 | 11:20h | UTC
Commentaries on Twitter
A multigene classifier reveals that malignant pediatric thyroid nodules have a unique molecular landscape vs those in adults. The classifier had a sensitivity of 96% & specificity of 78% for cancer detection & might reduce the need for diagnostic surgery: https://t.co/hdsPjGe9IR
— NatureRevClinOncol (@NatRevClinOncol) June 16, 2022
Pediatric thyroid cancer is on the rise. Its genomic landscape is unique; but, this retrospective case series shows that it may still be amenable to molecular classification—potentially decreasing diagnostic surgery & opening avenues for targeted therapy. https://t.co/KiYMsB1qGM
— JAMA Oncology (@JAMAOnc) June 10, 2022
Consensus Guidelines: Management of hematoma after thyroid surgery.
30 Jun, 2022 | 11:06h | UTC
Retrospective cohort study: Association of patient characteristics with postoperative mortality in children undergoing tonsillectomy.
22 Jun, 2022 | 11:14h | UTCAssociation of Patient Characteristics With Postoperative Mortality in Children Undergoing Tonsillectomy in 5 US States – JAMA (free for a limited period)
Neck circumference measurement for surveillance and early detection of hemorrhage after thyroidectomy: a diagnostic accuracy study.
10 Jun, 2022 | 11:39h | UTCNeck Circumference Measurement for Surveillance and Early Detection of Hemorrhage After Thyroidectomy: A Diagnostic Accuracy Study – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Commentary on Twitter
Study evaluated neck circumference measurements as a diagnostic tool to improve patient’s safety in thyroid surgery. An increase of 7% or more seemed to be specific for post-thyroidectomy hemorrhage along with other clinical signs. https://t.co/HQqjv3svRx #thyroidectomy
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) June 9, 2022
Cohort Study: Analysis of comorbidities, clinical outcomes, and parathyroidectomy in adults with primary hyperparathyroidism.
8 Jun, 2022 | 10:38h | UTCRelated Study: Mortality and Morbidity in Mild Primary Hyperparathyroidism: Results From a 10-Year Prospective Randomized Controlled Trial of Parathyroidectomy Versus Observation – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
This national cohort study from Sweden found patients with primary hyperparathyroidism had an increased risk of fractures and cardiovascular events, and parathyroidectomy was associated with reduced risks for these outcomes. https://t.co/9dQAR9dqtk
— JAMA Network Open (@JAMANetworkOpen) June 3, 2022
Difficult and complicated oral ulceration: an expert consensus guideline for diagnosis.
6 Jun, 2022 | 11:19h | UTC
Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomized controlled trials.
31 May, 2022 | 11:50h | UTCRelated Study: Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial – The Lancet AND Commentary: Expensive antiseptics and sutures do not reduce the risk of surgical infections – National Institute for Health and Care Research
Commentary from one of the authors on Twitter (thread – click for more)
1. Today: our @TheLancetInfDis meta-analysis based on @FalconRct – triclosan sutures and alcoholic skin prep to reduce surgical site infection.
Link to open access PDF:https://t.co/cj7yFdbNpB pic.twitter.com/VkKRaxCAtm
— Aneel Bhangu (@aneelbhangu) May 27, 2022
Guidelines for clothing in the operating theatre.
30 May, 2022 | 11:52h | UTCGuidelines for clothing in the operating theatre, 2021 – Anaesthesia Critical Care & Pain Medicine
Systematic Review: Airway complications resulting from pediatric esophageal button battery impaction.
27 May, 2022 | 11:49h | UTCAirway Complications Resulting From Pediatric Esophageal Button Battery Impaction: A Systematic Review – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Invited Commentary: Pediatric Button Battery Injuries—Current State and What’s Next? – JAMA Otolaryngology-Head & Neck Surgery
Health Technology Assessment: Molecular testing for thyroid nodules of indeterminate cytology.
25 May, 2022 | 10:42h | UTC
M-A: Complication rates of total thyroidectomy vs. hemithyroidectomy for treatment of papillary thyroid microcarcinoma.
11 May, 2022 | 10:59h | UTCComplication Rates of Total Thyroidectomy vs Hemithyroidectomy for Treatment of Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery (link to abstract – $ for full-text)
Commentary on Twitter
In this systematic review and #meta-analysis, complications in the surgical management of micropapillary #thyroid carcinoma increased with the extent of surgery performed, although complications and recurrence were low for both operations. https://t.co/Itf14o38Vu @wiscsurgery
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) May 6, 2022
ESMO Clinical Practice Guideline update on the use of systemic therapy in advanced thyroid cancer.
5 May, 2022 | 10:16h | UTC
RCT: Sintilimab vs. placebo in combination with chemotherapy as first line treatment for locally advanced or metastatic esophageal squamous cell carcinoma.
20 Apr, 2022 | 09:28h | UTC
Commentary on Twitter
Compared with placebo, sintilimab in combination with chemo showed significant benefits in overall survival and progression free survival as first line treatment in patients with advanced or metastatic oesophageal squamous cell carcinoma, finds study https://t.co/m8Gn3SBmCu
— The BMJ (@bmj_latest) April 19, 2022
Development and validation of machine learning models for predicting occult nodal metastasis in early-stage oral cavity squamous cell carcinoma.
20 Apr, 2022 | 09:14h | UTC
Commentary on Twitter
In this diagnostic modeling study, #MachineLearning models built with multi-institutional data showed potential to reduce morbidity from elective neck dissections with similar cancer outcomes in patients with early-stage oral cavity squamous cell carcinoma https://t.co/aRktgc0ms6
— JAMA Network Open (@JAMANetworkOpen) April 13, 2022
M-A of randomized trials: Intraoperative recurrent laryngeal nerve monitoring vs. visualization alone.
19 Apr, 2022 | 01:17h | UTC
Development and validation of a decision analytical model for posttreatment surveillance for patients with oropharyngeal carcinoma.
14 Apr, 2022 | 07:52h | UTC
M-A: The clinical effect and safety of new preoperative fasting time guidelines for elective surgery.
12 Apr, 2022 | 09:51h | UTCRelated:
Does my hospitalized patient need an NPO-after-midnight order preoperatively?
Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.