Pediatrics – Critical Care & Emergencies | Links Medicus Content Curation & Alerts in Medicine

Cohort Study: Explanatory diagnoses following hospitalization for a brief resolved unexplained event.

8 Oct, 2021 | 10:03h | UTC

Explanatory Diagnoses Following Hospitalization for a Brief Resolved Unexplained Event – Pediatrics

Neurological Effects of COVID-19 in Children.

1 Oct, 2021 | 10:40h | UTC

Neurological Effects of COVID-19 in Children – Pediatric Clinics of North America

RCT: Smart glasses for radial arterial catheterization in pediatric patients.

30 Sep, 2021 | 10:17h | UTC

Smart Glasses for Radial Arterial Catheterization in Pediatric Patients: A Randomized Clinical Trial – Anesthesiology

Commentary on Twitter

Via @_Anesthesiology: The use of smart glasses improved the first-attempt success rate of ultrasound-guided radial artery catheterization and reduced first-attempt procedure time and overall complication rates in pediatric patients. https://t.co/DkSXwbbcn1

— ASA® (@ASALifeline) September 28, 2021

RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.

24 Sep, 2021 | 09:00h | UTC

Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial – The Lancet

Commentary on Twitter

#Antibiotic resistance is a global public health threat.

New trial indicates, unless pneumonia is suspected, clinicians should provide safety-netting advice but not prescribe antibiotics for most children presenting with chest infections. https://t.co/mOwLG5rZd1 #AMR pic.twitter.com/b0c7Z5flQk

— The Lancet (@TheLancet) September 23, 2021

Podcast: Febrile Infants (based on the new AAP Guideline).

7 Sep, 2021 | 10:31h | UTC

#33: Febrile Infants – When Babies Are Too Hot – The Cribsiders

Original guideline:

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

Commentaries:

Landmark Febrile Neonate, Febrile Infant Guideline from the AAP – JournalFeed

Small Talk – Hot Off The Presses: The Latest AAP Guidelines for the Febrile Neonate – emDocs

M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis

[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

Study: Clinical Prediction Rule to Identify Febrile Infants at Low Risk for Serious Bacterial Infections

Cohort Study: Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

Position paper on the diagnosis and management of pediatric acute liver failure.

6 Sep, 2021 | 10:31h | UTC

North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure – Journal of Pediatric Gastroenterology and Nutrition

The Role of Lung Ultrasound in the Management of the Critically Ill Neonate—A Narrative Review and Practical Guide.

3 Sep, 2021 | 10:00h | UTC

The Role of Lung Ultrasound in the Management of the Critically Ill Neonate—A Narrative Review and Practical Guide – Children

Study casts doubt on WHO guidance on antibiotics for neonatal sepsis.

3 Sep, 2021 | 09:57h | UTC

Study casts doubt on WHO guidance on antibiotics for neonatal sepsis – CIDRAP

Original study: Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS) – The Lancet Infectious Diseases

Invited commentary: Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here? (free registration required)

Commentary on Twitter

"WHO recommends ampicillin in combination with gentamicin for the management of clinical neonatal sepsis; however, there are persistent concerns regarding antimicrobial resistance and therapeutic failures with this treatment" #PIDTwitter #IDTwitter #medtwitter #TwitteRx https://t.co/FDlXwugouU

— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 9, 2021

Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review - short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.

2 Sep, 2021 | 08:19h | UTC

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Commentary/Podcast: are the AAP guidelines for the evaluation and management of the well-appearing febrile infant the answer to a never ending story?

27 Aug, 2021 | 08:40h | UTC

SGEM#341: are the AAP guidelines for the evaluation and management of the well-appearing febrile infant the answer to a never ending story? – The Skeptics Guide To EM

Original guideline and commentary: Commentary on the Latest AAP Guidelines for the Febrile Neonate.

Review: Managing diabetic ketoacidosis in children.

24 Aug, 2021 | 08:46h | UTC

Managing Diabetic Ketoacidosis in Children – Annals of Emergency Medicine

Doubts raised about cooling treatment for oxygen-deprived newborns.

19 Aug, 2021 | 08:38h | UTC

Doubts raised about cooling treatment for oxygen-deprived newborns – Nature

Original study: RCT: Therapeutic hypothermia may cause harm in moderate or severe neonatal encephalopathy in low-income and middle-income countries.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

13 Aug, 2021 | 10:01h | UTC

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison – American Family Physician

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Pediatric asthma: The REGAP consensus.

8 Aug, 2021 | 23:45h | UTC

Pediatric asthma: The REGAP consensus – Anales de Pediatría

AARC Guideline: Management of pediatric patients with oxygen in the acute care setting.

8 Aug, 2021 | 23:43h | UTC

AARC Clinical Practice Guideline: Management of Pediatric Patients With Oxygen in the Acute Care Setting – Respiratory Care – American Association for Respiratory Care

Review of COVID-19: Abdominal manifestations in adults and multisystem inflammatory syndrome in children.

6 Aug, 2021 | 10:05h | UTC

Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children – Clinical Imaging

PIDS-IDSA Guideline on diagnosis and management of acute hematogenous osteomyelitis in pediatrics.

6 Aug, 2021 | 09:58h | UTC

Clinical Practice Guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 Guideline on Diagnosis and Management of Acute Hematogenous Osteomyelitis in Pediatrics – Journal of the Pediatric Infectious Diseases Society

News release: New PIDS-IDSA guideline on bone infections in children addresses key diagnostic and treatment questions – Pediatric Infectious Diseases Society

RCT: Therapeutic hypothermia may cause harm in moderate or severe neonatal encephalopathy in low-income and middle-income countries.

5 Aug, 2021 | 08:43h | UTC

Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh – The Lancet Global Health

News release: Brain injury treatment may cause harm in low and middle income nations – Imperial College London

Commentary: Hypoxic ischaemic encephalopathy in low resource settings—time to stop cooling? – The Lancet Global Health

Commentary on the Latest AAP Guidelines for the Febrile Neonate.

5 Aug, 2021 | 08:36h | UTC

Small Talk – Hot Off The Presses: The Latest AAP Guidelines for the Febrile Neonate – emDocs

Original guideline:

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis

[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

Study: Clinical Prediction Rule to Identify Febrile Infants at Low Risk for Serious Bacterial Infections

Cohort Study: Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

RCT: Effect of a sedation and ventilator liberation protocol vs. usual care on duration of invasive mechanical ventilation in pediatric intensive care units.

4 Aug, 2021 | 08:59h | UTC

Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary on Twitter

In this stepped-wedge, cluster RCT, among infants and children anticipated to require prolonged mechanical ventilation, a sedation & ventilator liberation protocol intervention resulted in a reduction in time to first successful extubation https://t.co/oNuOq9CCrs pic.twitter.com/n9l3MOJlop

— JAMA (@JAMA_current) August 3, 2021

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

3 Aug, 2021 | 09:05h | UTC

Six Month Follow-up of Patients With Multisystem Inflammatory Syndrome in Children – Pediatrics (PDF)

Cohort study: Neurological manifestations of SARS-CoV-2 infection in hospitalized children and adolescents in the UK – “around 1 in 20 of children hospitalized with COVID-19 develop brain or nerve complications linked to the viral infection”.

26 Jul, 2021 | 02:58h | UTC

Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study – The Lancet Child & Adolescent Health

Commentaries:

Neuroinflammation triggered by SARS-CoV-2 infection: syndromes and therapies – The Lancet Child & Adolescent Health

New UK study reveals extent of brain complications in children hospitalized with COVID-19 – University of Liverpool

Commentary on Twitter

A UK national prospective study of brain involvement in children hospitalized with covid: wide range of neurologic complications in 51 kidshttps://t.co/4JvjbthgH4 @LancetChildAdol pic.twitter.com/IiXF9bVmKz

— Eric Topol (@EricTopol) July 14, 2021