Pediatrics – Critical Care & Emergencies
Systematic Review | Home care for bronchiolitis.
21 Sep, 2022 | 13:14h | UTCHome Care for Bronchiolitis: a Systematic Review – Pediatrics
Commentary on Twitter
Given the growing interest in and potential impact of the Hospital-at-Home model, this review helps determine whether bronchiolitis requiring hospital-level care is feasible, acceptable to families, and can be safely managed in the home: https://t.co/eISjhYmRdd #Pediatrics pic.twitter.com/qjJYSDUTOq
— AAP Pediatrics (@aap_peds) September 6, 2022
Review | Aerosol delivery of lung surfactant and nasal CPAP in the treatment of neonatal respiratory distress syndrome.
19 Sep, 2022 | 12:29h | UTC
RCT | Among neonates with probable bacterial infection, switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) was noninferior to a full course of intravenous antibiotics and resulted in shorter hospitalization (median duration of 3.4 vs. 6.8 days).
16 Sep, 2022 | 12:59h | UTCEfficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary: Dutch team devise less painful ‘drip and drink’ antibiotics treatment for babies – Dutch News
Commentaries on Twitter
*New trial*—early switch to #OralAntibiotics is not inferior to full-course IV antibiotics in #neonates with probable bacterial infection; & adverse events were not increased with use of oral antibiotics
By @IKMReiss @karelallegaert & colleagues
https://t.co/2yzeh3ptuc pic.twitter.com/BgBosxfECC
— The Lancet Child & Adolescent Health (@LancetChildAdol) September 12, 2022
In term and near-term infants <28 days with probable bacterial infection, how safe is it to switch to oral Amox-Clav as opposed to completing a course of intravenous antibiotics? A new RCT in @Lancet tries to answer this question.https://t.co/M2Za54cfxF#EBNeoAlerts#NeoEBM pic.twitter.com/zKpIiW1Whx
— Evidence-Based Neo (@EBNEO) September 12, 2022
(Thread – click for more)
Efficacy & safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) vs full course of IV antibiotics in neonates with probable bacterial infection (RAIN):multicentre, randomised,open-label,non-inferiority trial -The Lancet https://t.co/mcyr9bILRq
— Prof. Dr. Sanjeev Bagai (@BagaiDr) September 13, 2022
Review | Multisystem inflammatory syndrome in children (MIS-C) and neonates (MIS-N) associated with COVID-19: optimizing definition and management.
14 Sep, 2022 | 13:15h | UTC
Commentary on Twitter
Proposed classification of Multisystem inflammatory syndrome in #neonates (MIS-N)
Clinical features
Treatment and immunological mechanisms#MISC #covid19 #PIMSTS #PedsICU#NeoEBM @DrSBagci #NeoTwitter #Neonatology @DrKenRemy1 @ChrisCarrollMD @lizWWyld https://t.co/tDuM51GMr4 pic.twitter.com/PNobOOzevX— Yonca Bulut M.D. (@yoncabulutmd) September 6, 2022
Under a http://creativecommons.org/licenses/by/4.0/ License
Review | Nutritional support for pediatric severe traumatic brain injury.
14 Sep, 2022 | 13:04h | UTCNutritional Support for Pediatric Severe Traumatic Brain Injury – Frontiers in Pediatrics
Systematic Review | Long-term outcomes after non-traumatic out-of-hospital cardiac arrest in pediatric patients.
11 Sep, 2022 | 22:30h | UTC
Review | COVID-19 in children.
8 Sep, 2022 | 14:43h | UTCCOVID-19 in Children – Pediatric Clinics of North America
Pediatric infective endocarditis: a literature review.
8 Sep, 2022 | 14:31h | UTCPediatric Infective Endocarditis: A Literature Review – Journal of Clinical Medicine
Brief Review | What’s new in pediatric ventilator liberation?
5 Sep, 2022 | 14:29h | UTCWhat’s new in paediatric ventilator liberation? – Intensive Care Medicine
Commentary on Twitter
Pediatric ventilator liberation, update
⚙️ assess/adjustment of MV & sedation
⚙️ prepare
⚙️ extubate
⚙️ support
Many questions unanswered! peri-extubation steroids, criteria for NIV after extubation, post-extubation rescue HFNC vs CPAP.#PedsICU #FOAMcc
🖇️ https://t.co/MGPStTvZh2 pic.twitter.com/AySzk9blS5— Intensive Care Medicine (@yourICM) September 2, 2022
Perspective | Should less invasive surfactant administration (LISA) become routine practice in US neonatal units?
29 Aug, 2022 | 11:59h | UTCRelated:
Measuring quality of dying, death and end-of-life care for children and young people: a scoping review of available tools.
26 Aug, 2022 | 13:14h | UTC
Hospitalizations for unintentional cannabis poisonings among Canadian children surged after legalization.
25 Aug, 2022 | 12:07h | UTCOriginal Study: Edible Cannabis Legalization and Unintentional Poisonings in Children – New England Journal of Medicine ($)
AAP Updated Clinical Report | The use of systemic and topical fluoroquinolones.
17 Aug, 2022 | 14:19h | UTCThe Use of Systemic and Topical Fluoroquinolones – Pediatrics
International clinical practice guidelines for pediatric ventilator liberation.
16 Aug, 2022 | 13:56h | UTC
NICE Guideline | Urinary tract infection in under 16s: diagnosis and management.
15 Aug, 2022 | 12:34h | UTC
Pediatric acute liver failure: reexamining key clinical features, current management, and research prospects.
12 Aug, 2022 | 14:17h | UTC
AAP Guideline Update | Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.
9 Aug, 2022 | 13:00h | UTC
M-A | The outcome of post-cardiotomy extracorporeal membrane oxygenation in neonates and pediatric patients.
4 Aug, 2022 | 13:48h | UTC
Brief Review | Lung ultrasound for the diagnosis and management of neonatal respiratory distress syndrome.
4 Aug, 2022 | 13:45h | UTC
Management of hypertensive crises in children: a review of the recent literature.
4 Aug, 2022 | 13:42h | UTC
Podcast | Caring for a pediatric patient with ARDS.
4 Aug, 2022 | 13:35h | UTC#52: The Original “Baby Lung”: PARDS with PedsCrit – The Cribsiders
Cohort Study | Comparison of diagnostic criteria for acute kidney injury in critically ill children.
15 Jul, 2022 | 12:17h | UTC
A case series of children with acute hepatitis and human Adenovirus infection.
14 Jul, 2022 | 12:56h | UTCA Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Related Study: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (free registration required)
Commentaries on Twitter
A majority of children admitted to a single hospital in late 2021–early 2022 with acute hepatitis of unknown cause tested positive for adenovirus. This report describes the children’s illnesses and outcomes. https://t.co/QYvi6U1jUN pic.twitter.com/auPRq1duQm
— NEJM (@NEJM) July 13, 2022
From January–April 2022, 44 children with acute hepatitis of unknown cause were referred to a liver-transplantation center in the U.K. Six underwent liver transplantation. https://t.co/CMI4KCqdxM pic.twitter.com/og72u58L5R
— NEJM (@NEJM) July 13, 2022
WHO Updated Report | Severe acute hepatitis of unknown etiology in children.
14 Jul, 2022 | 12:54h | UTCSevere acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Related:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
RCT | Erythropoietin not beneficial for hypoxic-ischemic encephalopathy in newborns.
14 Jul, 2022 | 12:42h | UTCTrial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns – New England Journal of Medicine (link to abstract – $ for full-text)