Pediatrics - Critical Care & Emergencies
AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.
20 Jul, 2021 | 10:14h | UTCEvaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old – Pediatrics
News Release: AAP releases clinical practice guideline on well-appearing febrile infants – AAP News
New Zealand children falling ill in high numbers due to Covid ‘immunity debt’.
14 Jul, 2021 | 11:16h | UTCNew Zealand children falling ill in high numbers due to Covid ‘immunity debt’ – The Guardian
Related: New Zealand, where Covid-19 is dormant, fights another respiratory virus – The New York Times
[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.
12 Jul, 2021 | 03:12h | UTCCommentaries: Risks of severe illness in children from COVID-19 shown to be very low in largest study yet – University of Liverpool AND Covid: Children’s extremely low risk confirmed by study – BBC
Related study from the same group (preprint): Risk factors for intensive care admission and death amongst children and young people admitted to hospital with COVID-19 and PIMS-TS in England during the first pandemic year – medRxiv
AHA Scientific Statement: Diagnosis and Management of Myocarditis in Children.
9 Jul, 2021 | 10:10h | UTCNews release: Viruses are the most common cause of myocarditis in children, experts offer guidance – American Heart Association
Top Things to Know: Diagnosis and Management of Myocarditis in Children
CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.
24 Jun, 2021 | 09:51h | UTCSee also: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP
Related: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. AND CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.
18 Jun, 2021 | 08:36h | UTCTreatment of Multisystem Inflammatory Syndrome in Children – New England Journal of Medicine
Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics
Commentaries: Steroids may be effective treatment for COVID-19 complications in children – Imperial College London AND Expert reaction to study looking at treatments for COVID-19 complications in children – Science Media Centre
Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.
18 Jun, 2021 | 08:35h | UTCEditorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics
Audio Interview: potential treatments for children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19.
18 Jun, 2021 | 08:33h | UTCAudio Interview: Covid-19 in Children – New England Journal of Medicine
Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination.
17 Jun, 2021 | 09:43h | UTCCommentary: Possible Association Between COVID-19 Vaccine and Myocarditis – American College of Cardiology
Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination.
17 Jun, 2021 | 09:45h | UTCMyocarditis after BNT162b2 and mRNA-1273 Vaccination – Circulation
Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination.
17 Jun, 2021 | 09:41h | UTCRelated: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.
14 Jun, 2021 | 08:48h | UTCCommentary: MIS-C Incidence 316 Persons Per 1 Million SARS-CoV-2 Infections – HealthDay
Commentary on Twitter
About 1 in every 3,000 children who got COVID ended up with MIS-C. MIS-C incidence among Black persons and Hispanic or Latino persons was approximately 9x higher, and incidence among Asian or Pacific Islander persons was approximately 3x higher https://t.co/JTEsvgvFcz
— Daniel Griffin MD PhD (@DanielGriffinMD) June 12, 2021
Podcast | Shock in Children: diagnosis, treatment, and management of septic shock, cardiogenic shock, neurogenic shock, adrenal insufficiency, and more.
10 Jun, 2021 | 09:36h | UTC#27: Shock! A Deep Dive into Our First Intensive Topic – The Cribsiders
In youth, COVID-19 causes more complications than flu; fatality is rare.
9 Jun, 2021 | 08:23h | UTCOriginal study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics
Current state of analgesia and sedation in the pediatric intensive care unit.
9 Jun, 2021 | 08:09h | UTC
Difficult airway management in neonates and infants: knowledge of devices and a device-oriented strategy.
9 Jun, 2021 | 08:08h | UTC
Underlying medical conditions associated with severe COVID-19 illness among children – the strongest risk factors for hospitalization were chronic and complex chronic diseases, type 1 diabetes, and obesity.
8 Jun, 2021 | 09:37h | UTCCommentaries: Underlying illness, respiratory infection raise risk for severe COVID in kids – CIDRAP AND COVID-19 in Children—Not Just Little Adults – JAMA Network Open
Commentary on Twitter
This cross-sectional study found a higher risk of severe #COVID19 illness among children with medical complexity and certain underlying conditions, such as type 1 diabetes, cardiac and circulatory congenital anomalies, and obesity. https://t.co/ifq1Ao0HKS
— JAMA Network Open (@JAMANetworkOpen) June 7, 2021
Transfusion management of severe anemia in African children: a consensus algorithm.
25 May, 2021 | 08:32h | UTC
RCT: In Africa, children hospitalized with severe pneumonia with oxygen saturations between 80 and 91% who did not receive oxygen had comparable mortality to children who received oxygen.
21 May, 2021 | 08:30h | UTC
Commentary on Twitter
COAST RCT O2 in African children >28 days w severe pneumonia, less is more!
SO2 80-91%? no O2 ➡️48h mortality comparable to low-flow O2/HFNC. O2-sparing strategies potentially offer cost-effective approaches to reduce requirements in low resource settings. https://t.co/8JHit94WQY pic.twitter.com/EEIybSOlmy— Intens Care Med (@yourICM) May 6, 2021
M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.
21 May, 2021 | 08:24h | UTC
Commentary on Twitter
This metanalysis found positive urinalysis alone is not an indication for LP in well looking febrile infants >28 days old. Prevalence among UA-positive infants: 0.4% vs UA-negative infants: 0.5%. https://t.co/dTzCiLHrSg
— JAMA Network Open (@JAMANetworkOpen) May 12, 2021
Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.
19 May, 2021 | 08:20h | UTC
Commentary on Twitter
Is giving surfactant via minimally invasive technique involving placement of a thin catheter in the trachea of a spontaneously breathing #infant effective and safe? https://t.co/0TKceRx4Oh New #SystematicReview from @CochraneNeonate looks at the evidence from 6 randomised trials. pic.twitter.com/qPB3Q0vp9E
— Cochrane UK (@CochraneUK) May 15, 2021
Cohort study of 12,306 pediatric COVID-19 patients finds only 16.5% presented with typical respiratory symptoms (cough, dyspnea). 13.9% had GI symptoms, 8.1% had dermatological symptoms (rash), 4.8% had neurological (headache), and 18.8% had other non-specific symptoms (fever, malaise, myalgia, arthralgia and disturbances of smell or taste).
14 May, 2021 | 08:48h | UTCCommentary: COVID-19: Majority of infected children may not show typical symptoms – Nature Publishing Group
Commentary on Twitter
A retrospective cohort study of 12,306 pediatric COVID-19 patients
📍5% require hospitalization
📍18% of these require critical care
📍4% of these require ventilation
https://t.co/X6MTdS8D1i— Rick MaskDonald MD 🚴♂️🏄🏻🎾 (@Kidsdoc1Rick) May 13, 2021
RCT: Discontinuing nasal continuous positive airway pressure either at 5 cm H2O vs. 3 cm H2O in infants ≤32 weeks of gestational age
3 May, 2021 | 05:15h | UTCDiscontinuing Nasal Continuous Positive Airway Pressure in Infants ≤32 Weeks of Gestational Age: A Randomized Control Trial – The Journal of Pediatrics (link to abstract – $ for full-text)
Commentary on Twitter
Randomized trial finds stopping CPAP at 5 cm H2O versus weaning until 3 cm H2O & then stopping is no different except babies will less likely to fail the initial attempt of discontinuation in weaning group (wean until 3 cm & then stop)@EBNEO @JPediatr https://t.co/G5yNK3fD1b
— Abdul Razak, MD, FRCPCH (@DrAbdulRazak_MD) October 27, 2020
Podcast: Congenital Heart Disease for the General Pediatrician
29 Apr, 2021 | 08:18h | UTC#24: Congenital Heart Disease for the General Pediatrician – The Cribsiders
Pediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic
28 Apr, 2021 | 08:33h | UTC
Commentary on Twitter
Impact of #COVID19 #pandemic on #PedsICU: less visible vs adult ICU but all-pervasive, substantial & likely long-lasting
➡️on children
➡️on families
➡️on organizations
➡️on PICU team@Dr_Hari_Krishna @PollakUri Shekerdemian L #FOAMcc #COVIDFOAM on @yourICM https://t.co/OyI9etm1a2 pic.twitter.com/1bqi1oKlMk— Intens Care Med (@yourICM) April 27, 2021