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Pediatrics - Critical Care & Emergencies

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

20 Jul, 2021 | 10:14h | UTC

Evaluation and Management of Well-Appearing Febrile Infants 8 to 60 Days Old – Pediatrics

News Release: AAP releases clinical practice guideline on well-appearing febrile infants – AAP News

 


New Zealand children falling ill in high numbers due to Covid ‘immunity debt’.

14 Jul, 2021 | 11:16h | UTC

New Zealand children falling ill in high numbers due to Covid ‘immunity debt’ – The Guardian

Related: New Zealand, where Covid-19 is dormant, fights another respiratory virus – The New York Times


[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.

12 Jul, 2021 | 03:12h | UTC

Original study (preprint): Deaths in Children and Young People in England following SARS-CoV-2 infection during the first pandemic year: a national study using linked mandatory child death reporting data – National Child Mortality Database / Public Health England

Commentaries: Risks of severe illness in children from COVID-19 shown to be very low in largest study yet – University of Liverpool AND Covid: Children’s extremely low risk confirmed by study – BBC

Related study from the same group (preprint): Risk factors for intensive care admission and death amongst children and young people admitted to hospital with COVID-19 and PIMS-TS in England during the first pandemic year – medRxiv

 


AHA Scientific Statement: Diagnosis and Management of Myocarditis in Children.

9 Jul, 2021 | 10:10h | UTC

Diagnosis and Management of Myocarditis in Children: A Scientific Statement From the American Heart Association – Circulation

News release: Viruses are the most common cause of myocarditis in children, experts offer guidance – American Heart Association

Top Things to Know: Diagnosis and Management of Myocarditis in Children

 


CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.

24 Jun, 2021 | 09:51h | UTC

CDC safety group says there’s a likely link between rare heart inflammation in young people after Covid shot – CNBC

See also: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP

Related: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. AND CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.

 


Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

18 Jun, 2021 | 08:36h | UTC

Treatment of Multisystem Inflammatory Syndrome in Children – New England Journal of Medicine

Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics

Commentaries: Steroids may be effective treatment for COVID-19 complications in children – Imperial College London AND Expert reaction to study looking at treatments for COVID-19 complications in children – Science Media Centre

 


Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

18 Jun, 2021 | 08:35h | UTC

Multisystem Inflammatory Syndrome in Children — Initial Therapy and Outcomes – New England Journal of Medicine

Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics

 


Audio Interview: potential treatments for children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19.

18 Jun, 2021 | 08:33h | UTC

Audio Interview: Covid-19 in Children – New England Journal of Medicine

 


Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination.

17 Jun, 2021 | 09:43h | UTC

Possible Association Between COVID-19 Vaccine and Myocarditis: Clinical and CMR Findings – JACC: Cardiovascular Imaging

Commentary: Possible Association Between COVID-19 Vaccine and Myocarditis – American College of Cardiology

Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.

 


Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination.

17 Jun, 2021 | 09:45h | UTC

Myocarditis after BNT162b2 and mRNA-1273 Vaccination – Circulation

Commentary: Study details the treatment of COVID-19 vaccine-associated myocarditis-like illness in 7 patients – News Medical

Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.

 


Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination.

17 Jun, 2021 | 09:41h | UTC

Symptomatic Acute Myocarditis in Seven Adolescents Following Pfizer-BioNTech COVID-19 Vaccination – Pediatrics

Related: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.

 


Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

14 Jun, 2021 | 08:48h | UTC

Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2 – JAMA Network Open

Commentary: MIS-C Incidence 316 Persons Per 1 Million SARS-CoV-2 Infections – HealthDay

 

Commentary on Twitter

 


Podcast | Shock in Children: diagnosis, treatment, and management of septic shock, cardiogenic shock, neurogenic shock, adrenal insufficiency, and more.

10 Jun, 2021 | 09:36h | UTC

#27: Shock! A Deep Dive into Our First Intensive Topic – The Cribsiders

 


In youth, COVID-19 causes more complications than flu; fatality is rare.

9 Jun, 2021 | 08:23h | UTC

In youth, COVID-19 causes more complications than flu; fatality is rare – Columbia University Irving Medical Center

Original study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics

 


Current state of analgesia and sedation in the pediatric intensive care unit.

9 Jun, 2021 | 08:09h | UTC

Current State of Analgesia and Sedation in the Pediatric Intensive Care Unit – Journal of Clinical Medicine

 


Difficult airway management in neonates and infants: knowledge of devices and a device-oriented strategy.

9 Jun, 2021 | 08:08h | UTC

Difficult Airway Management in Neonates and Infants: Knowledge of Devices and a Device-Oriented Strategy – Frontiers in Pediatrics

 


Underlying medical conditions associated with severe COVID-19 illness among children – the strongest risk factors for hospitalization were chronic and complex chronic diseases, type 1 diabetes, and obesity.

8 Jun, 2021 | 09:37h | UTC

Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children – JAMA Network Open

Commentaries: Underlying illness, respiratory infection raise risk for severe COVID in kids – CIDRAP AND COVID-19 in Children—Not Just Little Adults – JAMA Network Open

 

Commentary on Twitter

 


Transfusion management of severe anemia in African children: a consensus algorithm.

25 May, 2021 | 08:32h | UTC

Transfusion management of severe anaemia in African children: a consensus algorithm – British Journal of Haematology

 


RCT: In Africa, children hospitalized with severe pneumonia with oxygen saturations between 80 and 91% who did not receive oxygen had comparable mortality to children who received oxygen.

21 May, 2021 | 08:30h | UTC

Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia – Intensive Care Medicine

 

Commentary on Twitter

 


M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

21 May, 2021 | 08:24h | UTC

Prevalence of Bacterial Meningitis Among Febrile Infants Aged 29-60 Days With Positive Urinalysis Results: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.

19 May, 2021 | 08:20h | UTC

Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome – Cochrane Library

Summary: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome – Cochrane Library

 

Commentary on Twitter

 


Cohort study of 12,306 pediatric COVID-19 patients finds only 16.5% presented with typical respiratory symptoms (cough, dyspnea). 13.9% had GI symptoms, 8.1% had dermatological symptoms (rash), 4.8% had neurological (headache), and 18.8% had other non-specific symptoms (fever, malaise, myalgia, arthralgia and disturbances of smell or taste).

14 May, 2021 | 08:48h | UTC

A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States – Scientific Reports

Commentary: COVID-19: Majority of infected children may not show typical symptoms – Nature Publishing Group

 

Commentary on Twitter

 


RCT: Discontinuing nasal continuous positive airway pressure either at 5 cm H2O vs. 3 cm H2O in infants ≤32 weeks of gestational age

3 May, 2021 | 05:15h | UTC

Discontinuing Nasal Continuous Positive Airway Pressure in Infants ≤32 Weeks of Gestational Age: A Randomized Control Trial – The Journal of Pediatrics (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Podcast: Congenital Heart Disease for the General Pediatrician

29 Apr, 2021 | 08:18h | UTC

#24: Congenital Heart Disease for the General Pediatrician – The Cribsiders

 


Pediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic

28 Apr, 2021 | 08:33h | UTC

Paediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic – Intensive Care Medicine

 

Commentary on Twitter

 


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