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Hypertension

M-A | Blood pressure, hypertension and the risk of atrial fibrillation

1 Feb, 2023 | 13:22h | UTC

Blood pressure, hypertension and the risk of atrial fibrillation: a systematic review and meta-analysis of cohort studies – European Journal of Epidemiology

 


Guidelines for the management of hypertension in patients with diabetes mellitus

1 Feb, 2023 | 13:17h | UTC

RSSDI Guidelines for the management of hypertension in patients with diabetes mellitus – International Journal of Diabetes in Developing Countries

 


Perspective | Is it time to retire the diagnosis “hypertensive emergency”?

27 Jan, 2023 | 12:26h | UTC

Is it Time to Retire the Diagnosis “Hypertensive Emergency”? – Journal of the American Heart Association

 


SR | Does reducing your salt intake help to prevent and treat chronic kidney disease in people with diabetes?

25 Jan, 2023 | 11:30h | UTC

Altered dietary salt intake for preventing diabetic kidney disease and its progression – Cochrane Library

Summary: Does reducing your salt intake help to prevent and treat chronic kidney disease in people with diabetes? – Cochrane Library

 


RCT | Home vs. kiosk vs. clinic blood pressure measurement compared to 24-h ambulatory monitoring

25 Jan, 2023 | 11:28h | UTC

Acceptability and Adherence to Home, Kiosk, and Clinic Blood Pressure Measurement Compared to 24-H Ambulatory Monitoring – Journal of General Internal Medicine

Original Study: Randomized Diagnostic Study: home blood pressure measurements correlate better with 24-h ambulatory monitoring measurements compared to clinic, and kiosk measurements.

Related:

Home blood pressure monitoring: a position statement from the Korean Society of Hypertension Home Blood Pressure Forum – Clinical Hypertension

2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement – Journal of Hypertension

Current applications and limitations of European guidelines on blood pressure measurement: implications for clinical practice – Internal and Emergency Medicine

Study suggests a 30-second interval between automated office blood pressure measurements is as accurate and reliable as a 60-second interval.

USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment

Study suggests that 7 days of home blood pressure monitoring is likely better than 24h ambulatory monitoring or 3 office measurements

 


RCT | Effect of a multicomponent intervention delivered on a web-based platform on hypertension control

24 Jan, 2023 | 14:12h | UTC

Effect of a Multicomponent Intervention Delivered on a Web-Based Platform on Hypertension Control: A Cluster Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


AHA Statement | Cancer therapy-related hypertension

23 Jan, 2023 | 13:46h | UTC

Cancer Therapy–Related Hypertension: A Scientific Statement From the American Heart Association – Hypertension

Top Things to Know: Cancer Therapy-Related HTN – American Heart Association

Commentary: Cancer and hypertension induced by anticancer drugs: The need for increased awareness, improved detection and proactive management – American Heart Association

 


Cohort Study | Increased coffee consumption linked to increased CVD risk in patients with severe hypertension

20 Jan, 2023 | 14:53h | UTC

Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People With and Without Hypertension – Journal of the American Heart Association

News Release: Drinking 2 or more cups of coffee daily may double risk of heart death in people with severe hypertension – American Heart Association

Commentaries:

Expert reaction to study looking at coffee and green tea consumption and heart deaths in people with severe high blood pressure – Science Media Centre

Hypertension and Heavy Coffee Consumption a Bad Combo, Study Finds – TCTMD

 


Metomidate PET-CT vs. adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

19 Jan, 2023 | 14:19h | UTC

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial – Nature Medicine

News Release: Ten-minute scan enables detection and cure of the commonest cause of high blood pressure – Queen Mary University of London

 


RCT | Chlorthalidone (12.5-25 mg) and Hydrochlorothiazide (25-50 mg) are similarly effective for the prevention of CVD in hypertensive patients.

16 Dec, 2022 | 13:49h | UTC

Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: ‘Burden-free’ study method finds two blood pressure drugs equally effective – Veterans Affairs Research Communications

Related (news release and commentaries before publication): RCT | Chlortalidone and Hydrochlorothiazide resulted in similar reductions of CVD in older patients with hypertension.

 

Commentary on Twitter

 


Cluster RCT | Effect of a multicomponent intervention delivered on a web-based platform on hypertension control.

8 Dec, 2022 | 13:02h | UTC

Effect of a Multicomponent Intervention Delivered on a Web-Based Platform on Hypertension Control: A Cluster Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


Cohort Study | Adding salt to foods linked to increased risk of cardiovascular disease.

6 Dec, 2022 | 14:04h | UTC

Adding Salt to Foods and Risk of Cardiovascular Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)

News Release: Shaking less salt on your food at the table could reduce heart disease risk – American College of Cardiology

Commentaries:

Adding Salt to Food and Risk of Cardiovascular Disease – American College of Cardiology

Lower Frequency of Adding Salt to Food Linked to Lower CVD Risk – HealthDay

 


Review | Blood pressure elevations in hospital.

6 Dec, 2022 | 13:31h | UTC

Blood pressure elevations in hospital – Australian Prescriber

Commentary: Overuse of in-hospital blood pressure medications – Flinders University

Related: Hypertension in the hospitalized patient: An update – Nefrología 

 


M-A | Thiazide diuretics and fracture risk.

29 Nov, 2022 | 14:23h | UTC

Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – JBMR Plus

 


SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.

22 Nov, 2022 | 13:39h | UTC

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease – Cochrane Library 

Summary: Blood pressure targets in people with cardiovascular disease – Cochrane Library 

 

Commentary on Twitter 

 


RCT | Dual endothelin antagonist Aprocitentan is effective for resistant hypertension.

11 Nov, 2022 | 13:59h | UTC

Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentaries:

Endothelin Receptor Antagonist Effective in Resistant Hypertension: PRECISION – TCTMD

Parallel-Group, Phase 3 Study With Aprocitentan in Subjects With Resistant Hypertension – PRECISION – American College of Cardiology

 


Phase 2RCT | Baxdrostat reduces BP in patients with treatment-resistant hypertension.

11 Nov, 2022 | 13:57h | UTC

Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Big Drops in Blood Pressure With Baxdrostat: BrigHTN Phase II Study – TCTMD

New Drug Helps Tame Uncontrolled High Blood Pressure – HealthDay

 


RCT | Chlortalidone and Hydrochlorothiazide resulted in similar reductions of CVD in older patients with hypertension.

7 Nov, 2022 | 12:50h | UTC

News Release (not published yet): No difference in heart outcomes found in use of two diuretics to treat blood pressure – American Heart Association

Commentaries:

In High BP, Chlorthalidone and Hydrochlorothiazide Have Similar Impact on MACE – TCTMD

Diuretic Comparison Project – DCP – American College of Cardiology

 


RCT | Discontinuing RAS inhibitors in patients with advanced CKD did not result in a slower decline in eGFR.

4 Nov, 2022 | 13:55h | UTC

Renin–Angiotensin System Inhibition in Advanced Chronic Kidney Disease – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | Blood pressure lowering and prevention of dementia.

4 Nov, 2022 | 13:46h | UTC

Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis – European Heart Journal

News Release: Best evidence yet that lowering blood pressure can prevent dementia – George Institute for Global Health

Commentary: Meta-Analysis Shows Decrease in Dementia Risk With HTN Treatment – HealthDay 

 


Cross-Sectional Study | Prevalence of and factors associated with high blood pressure among adolescents in India.

3 Nov, 2022 | 13:57h | UTC

Prevalence of and Factors Associated With High Blood Pressure Among Adolescents in India – JAMA Network Open

Invited Commentary: Prevalence of High Blood Pressure Among Youth in India and Association With Future Cardiovascular Disease – JAMA Network Open

 

Commentary on Twitter

 


Cohort Study | ARBs linked to decreased incidence of epilepsy compared with other antihypertensives.

19 Oct, 2022 | 14:18h | UTC

Association Between Angiotensin Receptor Blocker Therapy and Incidence of Epilepsy in Patients With Hypertension – JAMA Neurology (free for a limited period)

Related:

Loneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)

AHA Scientific Statement | Effects of objective and perceived social isolation on cardiovascular and brain health.

The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ

Social Isolation and Loneliness – World Health Organization

Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA

Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women – Heart

 


Perspective | The polypill: from concept and evidence to implementation.

18 Oct, 2022 | 12:55h | UTC

The polypill: from concept and evidence to implementation – The Lancet (free registration required)

News Release: The polypill could avoid millions of premature deaths, heart attacks and strokes every year, say leading cardiology experts – McMaster University

Related:

#ESCCongress | In patients within 6 months of a myocardial infarction, a polypill containing aspirin, ramipril, and atorvastatin resulted in a lower risk of major adverse cardiovascular events compared to usual care.

#ESCCongress – M-A: Polypills with and without aspirin substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention.

Opinion: A new important study supports wider use of the polypill

#AHA20 – Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk

Perspective: Are Polypills and Population-based Treatment the Next Big Things?

The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era

Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population

Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases

Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart

Perspective: The Polypill and the Long Journey to Major Impact

Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care

 


Post-trial follow-up | Longer-term all-cause and cardiovascular mortality with intensive blood pressure control.

17 Oct, 2022 | 12:41h | UTC

Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control: A Secondary Analysis of a Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

Author Interview: Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control – JAMA

Commentaries:

Benefits of Intensive Blood Pressure Control May Not Persist After Trial Intervention – HCP Live

Study Highlights Importance of Long-term Management of Hypertension – Wake Forest University School of Medicine

Related:

SPRINT Trial final report: targeting a systolic BP of less than 120 mm Hg in patients at increased CV risk is associated with improved CV and mortality outcomes but increases the risk of serious adverse events.

Study: Real-world blood pressure measurements vs. measurements taken in the SPRINT trial

Studies: Intensive versus Standard Blood-Pressure Control

 

Commentary on Twitter

 


Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study.

17 Oct, 2022 | 12:37h | UTC

Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study – Nature Medicine

See also:

News Release: New star rating system published in Nature Medicine helps people make informed decisions about diet and healthy habits – Institute for Health Metrics and Evaluation

Commentary: Expert reaction to studies presenting a standardized approach for quantifying the strength of evidence that supports associations between risk factors and health outcomes – Science Media Centre

Homepage: The Burden of Proof Studies – Nature Medicine

The Burden of Proof studies: assessing the evidence of risk

Health effects associated with vegetable consumption: a Burden of Proof study

Health effects associated with consumption of unprocessed red meat: a Burden of Proof study

Health effects associated with smoking: a Burden of Proof study

 

Commentary on Twitter

 


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