Hypertension
M-A | Effect of more vs. less intensive BP control on cardiovascular, renal and mortality outcomes in people with type 2 diabetes
29 May, 2023 | 10:37h | UTC
Cohort Study | Ambulatory blood pressure more predictive of mortality than clinic blood pressure
24 May, 2023 | 13:19h | UTCSummary: This cohort study analyzed the relationship between clinic and ambulatory blood pressure with mortality. The study utilized data from March 2004 to December 2014, sourced from the Spanish Ambulatory Blood Pressure Registry, which included 59,124 patients from 223 primary care centers across all regions of Spain. Patients were monitored until their date of death or until December 31, 2019.
During a median follow-up of 9.7 years, 7174 (12.1%) patients died, including 2361 (4.0%) due to cardiovascular causes. Findings revealed J-shaped associations for several blood pressure measures. Notably, 24-hour systolic blood pressure had a stronger association with all-cause death (HR 1.41 per 1 SD increment [95% CI 1.36–1.47]) than clinic systolic blood pressure. When adjusted for clinic blood pressure, the association between 24-hour blood pressure and all-cause death remained strong (HR 1.43 [95% CI 1.37–1.49]). Night-time systolic blood pressure was found to be the most predictive of all-cause and cardiovascular death.
The findings imply that ambulatory blood pressure, particularly night-time blood pressure, is more informative about the risk of all-cause death and cardiovascular death than clinic blood pressure. Masked hypertension and sustained hypertension were associated with increased mortality risks, but not white-coat hypertension. These results emphasize the importance of ambulatory blood pressure monitoring in hypertension management and risk prediction. Future research should focus on potential causes and strategies to control night-time blood pressure effectively, considering its substantial association with death risk.
Commentary: Tight Link Between Ambulatory BP and Mortality Affirmed in Revamped Analysis – TCTMD
Underdiagnosis of primary aldosteronism: a review of screening and detection
22 May, 2023 | 13:40h | UTC
Commentary on Twitter
Underdiagnosis of Primary Aldosteronism: A Review of Screening and Detection https://t.co/PYzSCZD2L7 (FREE)@MarioFunesMD @BhallaResearch @StanfordNeph pic.twitter.com/k7intLqpK3
— AJKD (@AJKDonline) May 19, 2023
Blood pressure variability in clinical practice: past, present and the future
11 May, 2023 | 12:13h | UTC
M-A | Intensive blood pressure control for patients aged over 60
11 May, 2023 | 12:07h | UTC
M-A | Fruit and vegetable consumption and the risk of hypertension
11 May, 2023 | 12:02h | UTC
International consensus on standardized clinic blood pressure measurement – a call to action
4 May, 2023 | 14:03h | UTCNews Release: KDIGO Announces Publication of International Consensus Statement on Standardized Blood Pressure Measurement
Commentary on Twitter
KDIGO is pleased to announce the publication of "International Consensus on Standardized Clinic Blood Pressure Measurement − A Call to Action" in The American Journal of Medicine. Read the News Release: https://t.co/OJbN0Lp8Et
Read the full statement: https://t.co/AmlVAVVcDD…
— KDIGO (@goKDIGO) May 1, 2023
AHA Scientific Statement | Hypertension in patients treated with in-center maintenance hemodialysis
2 May, 2023 | 14:02h | UTCTop Things to Know: HTN in Patients Treated with In-Center Maintenance Hemodialysis: Current Evidence and Future Opportunities – American Heart Association
Commentary on Twitter
❤️ New AHA statement reviews current evidence on defining, diagnosing & treating HTN in patients on maintenance hemodialysis + highlights research opportunities including studies on BP targets & treatment strategies. @HyperAHA
Read more: https://t.co/Cn5ktruTQA pic.twitter.com/7OTr3eQmrm
— AHA Science (@AHAScience) April 26, 2023
RCT | Hypotension-avoidance and hypertension-avoidance strategies resulted in similar outcomes in noncardiac surgery
2 May, 2023 | 13:54h | UTCHypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery: An International Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Hypotension-Avoidance No Better than Hypertension-Avoidance for Reducing Post-Op Adverse Events – HCP Live
Commentary on Twitter
Finally published-POISE-3 showed no diff in effects on major vasc complic between 2 alternative BP mgmt strategies. Probably easiest to continue current regimen.
Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery https://t.co/GIR4jAL07H— Steven Cohn, MD (@preopconsult) April 24, 2023
M-A | Low-dose triple and quadruple antihypertensives outperform monotherapy in blood pressure reduction
28 Apr, 2023 | 13:23h | UTCEfficacy and Safety of Low-Dose Triple and Quadruple Combination Pills vs Monotherapy, Usual Care, or Placebo for the Initial Management of Hypertension: A Systematic Review and Meta-analysis – JAMA Cardiology (free for a limited period)
Commentary: Low-Dose Polypills Top Other Approaches for Initial BP Control: Meta-analysis – TCTMD
Cohort Study | The association between antihypertensive treatment and serious adverse events by age and frailty
28 Apr, 2023 | 12:45h | UTC
Evidence Analysis | Blood pressure targets – how low can you get?
24 Apr, 2023 | 13:47h | UTCBlood pressure targets – how low can you get? – Evidently Cochrane
Original Article: SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.
Commentary on Twitter
Blood pressure targets – how low can you get? https://t.co/ERLm6Mihl8 In this @CochraneUK blog, GP @rtwalton123 looks at the latest guidance & @CochraneLibrary evidence on what #BloodPressure targets to aim for, balancing the benefits of treatment against risk of side effects. pic.twitter.com/8EQH0JLzzc
— The Cochrane Library (@CochraneLibrary) April 19, 2023
Guideline Update | Diagnosis and management of hypertension in pregnancy
24 Apr, 2023 | 13:43h | UTC
Joint statement for assessing and managing high blood pressure in children and adolescents
19 Apr, 2023 | 13:26h | UTCChapter 1: How to correctly measure blood pressure in children and adolescents – Frontiers in Pediatrics
Chapter 2: How to manage high blood pressure in children and adolescents – Frontiers in Pediatrics
Related:
AHA Scientific Statement | Pediatric primary hypertension: An underrecognized condition
AHA Scientific Statement: Ambulatory blood pressure monitoring in children and adolescents.
Cluster RCT | Salt substitute outperforms salt restriction in lowering blood pressure in older patients
18 Apr, 2023 | 13:30h | UTCSalt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial – Nature Medicine (if the link is paywalled, try this one)
Commentary: Exploring effectiveness of salt substitutes in elderly care facilities – Medical Xpress
Related:
Salt substitutes vs. regular salt: a quick look.
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Commentary on Twitter
In a cluster-randomized trial in 48 residential elderly care facilities in China, a low-sodium salt substitute instead of regular salt decreased blood pressure and cardiovascular events, while restricting salt consumption did not show beneficial effects https://t.co/Zp0fWH0aA2
— Nature Medicine (@NatureMedicine) April 13, 2023
Podcast | Resistant hypertension
18 Apr, 2023 | 13:16h | UTC#390 Resistant Hypertension – The Curbsiders
RCT | Heterogeneity in blood pressure response to 4 antihypertensive drugs
17 Apr, 2023 | 13:14h | UTCHeterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs: A Randomized Clinical Trial – JAMA (free for a limited period)
News Release: Personalized blood pressure treatment more effective – Uppsala University
Twenty‐four-hour ambulatory blood pressure profile in patients with reflex syncope vs. matched controls
12 Apr, 2023 | 13:21h | UTC
Sodium intake linked to both coronary & carotid atherosclerosis in the Swedish population
10 Apr, 2023 | 13:30h | UTC
Commentary on Twitter
Association between salt intake and both carotid and coronary atherosclerosis in a contemporary community-based cohort 👉https://t.co/sHTCEdu4Uw#EHJOpen @ehjopen @SaDeRosa78 #cardiotwitter
— European Society of Cardiology Journals (@ESC_Journals) April 3, 2023
Blood pressure targets in adults with hypertension | A clinical practice guideline from the AAFP
6 Apr, 2023 | 13:30h | UTCCommentary: AAFP Issues New Clinical Practice Guideline on Hypertension – Annals of Family Medicine
ACC/AHA blood pressure categories | Systematic review of adverse pregnancy outcomes in early pregnancy
6 Apr, 2023 | 12:53h | UTC
Commentary on Twitter
American College of Cardiology and American Heart Association blood pressure categories—a systematic review of the relationship with adverse pregnancy outcomes in the first half of pregnancy https://t.co/n3jWFLVYg5 pic.twitter.com/QzaWRyY4n5
— AJOG (@AJOG_thegray) March 31, 2023
M-A | Impact of antihypertensive therapy on maternal & neonatal outcomes in mild-moderate pregnancy hypertension
6 Apr, 2023 | 12:51h | UTC
Cross-sectional study | Association between sodium intake and coronary and carotid atherosclerosis
4 Apr, 2023 | 13:42h | UTCEditorial: Dietary salt intake and atherosclerosis: an area not fully explored – European Heart Journal Open
News Release: High salt diet associated with hardened arteries even in people with normal blood pressure – European Society of Cardiology
AHA Scientific Statement | Pediatric primary hypertension: An underrecognized condition
3 Apr, 2023 | 14:05h | UTCTop Things to Know: Pediatric Primary Hypertension: An Underrecognized Condition – American Heart Association
News Release: Children with high blood pressure often become adults with high blood pressure – American Heart Association
Commentaries:
The Birth of Pediatric Primary Hypertension – American Heart Association
AHA Highlights Pediatric Hypertension in Scientific Statement – HCP Live
Podcast | Pears in primary aldosteronism, mineralocorticoid receptor antagonists, and renovascular hypertension
29 Mar, 2023 | 13:07h | UTC