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Hypertension

Long-term follow-up of a RCT | Outcomes after catheter-based renal artery denervation for resistant hypertension.

20 Sep, 2022 | 13:33h | UTC

Long-term outcomes after catheter-based renal artery denervation for resistant hypertension: final follow-up of the randomised SYMPLICITY HTN-3 Trial – The Lancet (free registration required)

Commentary: SYMPLICITY HTN-3’s Late Surprise: Sustained BP Drop at 3 Years Despite Earlier Miss – TCTMD

Original Study: A Controlled Trial of Renal Denervation for Resistant Hypertension – New England Journal of Medicine

 


Nonadherence was revealed through measurements of serum concentrations of antihypertensive drugs in one-third of patients with resistant hypertension previously evaluated as adherent.

11 Sep, 2022 | 22:35h | UTC

Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7‐Year Follow‐Up of Patients Considered Adherent by Directly Observed Therapy – Journal of the American Heart Association

 


Review | The management of hypertensive emergencies—is there a “magical” prescription for all?

8 Sep, 2022 | 14:32h | UTC

The Management of Hypertensive Emergencies—Is There a “Magical” Prescription for All? – Journal of Clinical Medicine

 


Review/Perspective | European hypertension guideline downgrading of beta-blockers is not justified.

31 Aug, 2022 | 11:51h | UTC

Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified – Blood Pressure

 


Salt substitutes vs. regular salt: a quick look.

30 Aug, 2022 | 12:02h | UTC

Salt substitutes vs. regular salt: a quick look – Evidently Cochrane

Original Study: Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Related:

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Commentary on Twitter

 


M-A | Urban-rural differences in hypertension prevalence in low-income and middle-income countries, 1990–2020.

30 Aug, 2022 | 11:55h | UTC

Urban-rural differences in hypertension prevalence in low-income and middle-income countries, 1990–2020: A systematic review and meta-analysis – PLOS Medicine

News Release: Study shows urban-rural differences in hypertension prevalence in low-income and middle-income countries – News Medical

 

Commentary on Twitter

 


Study shows an increasing incidence of hypertensive disorders in pregnancy.

30 Aug, 2022 | 11:52h | UTC

Association of Birth Year of Pregnant Individuals With Trends in Hypertensive Disorders of Pregnancy in the United States, 1995-2019 – JAMA Network Open

Commentaries:

Increased incidence of hypertensive disorders of pregnancy in young Americans – News Medical

Hypertensive Disorders in Pregnancy on the Rise – AJMC

 

Commentary on Twitter

 


[News release – not published yet] #ESCCongres – RCT | Evening dosing of blood pressure medication not better than morning dosing.

29 Aug, 2022 | 12:30h | UTC

Evening dosing of blood pressure medication not better than morning dosing – European Society of Cardiology

Related Consensus Statement: Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related study (conflicting results): Bedtime Hypertension Treatment Improves Cardiovascular Risk Reduction in Randomized Trial

 


Bedtime dosing of antihypertensive medications: systematic review and consensus statement. – “use of bedtime drug dosing of antihypertensive drugs should not be routinely recommended”.

29 Aug, 2022 | 12:28h | UTC

Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension – Journal of Hypertension

Related: Evening dosing of blood pressure medication not better than morning dosing – European Society of Cardiology

 


RCT | Self-measurement of blood pressure with a standard device is not enhanced by the use of a connected smartphone application.

26 Aug, 2022 | 13:29h | UTC

Effectiveness of Standard vs Enhanced Self-measurement of Blood Pressure Paired With a Connected Smartphone Application: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

News Release: For Checking Blood Pressure at Home, Basic Cuffs Are Just as Good – UC San Francisco

Commentary: App-enabled device no better than standard device for self-measuring blood pressure – ACP Internist

 

Commentary on Twitter

 


Cross-Sectional Study | Hypertension common among poorest, least educated around the world.

22 Aug, 2022 | 12:14h | UTC

The Association of Socioeconomic Status With Hypertension in 76 Low- and Middle-Income Countries – Journal of the American College of Cardiology (link to abstract – $ for full-text)

News Release: Hypertension Common Among Poorest, Least Educated Around the World – American College of Cardiology

Editorial: Hypertension—A Silent Killer Without Global Bounds: What Next? – Journal of the American College of Cardiology

Commentary: Hypertension Common Among Poorest, Least Educated Globally – HealthDay

 

Commentary on Twitter

 


Cohort Study | Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease.

19 Aug, 2022 | 16:09h | UTC

News Release: Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease – European Society of Cardiology

Original Study: Aldosterone in chronic kidney disease and renal outcomes – European Heart Journal

Editorial: Aldosterone excess and cardiorenal risk: more common than appreciated – European Heart Journal

 

Commentary on Twitter

 


M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.

18 Aug, 2022 | 12:54h | UTC

Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis – Hypertension

 

Commentary on Twitter

 


Modeling Study | Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030.

18 Aug, 2022 | 12:42h | UTC

Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study – BMJ Nutrition Prevention & Health

News Release: 1 g cut in daily salt intake could ward off nearly 9 million cases of stroke/heart disease in China – BMJ Newsroom

 


Harmonization of American and European hypertension guidelines: comparisons, reflections, and recommendations.

12 Aug, 2022 | 15:19h | UTC

Harmonization of the American College of Cardiology/American Heart Association and European Society of Cardiology/European Society of Hypertension Blood Pressure/Hypertension Guidelines: Comparisons, Reflections, and Recommendations – European Heart Journal (also available at Circulation)

 


M-A | Effects of salt substitutes on clinical outcomes.

10 Aug, 2022 | 15:40h | UTC

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart

Commentary: Swapping salt for substitutes reduces risk of stroke and heart conditions – study – The Guardian

Related:

Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Commentary from the author on Twitter

 


Systematic Review | Replacing salt with low‐sodium salt substitutes for cardiovascular health in adults, children and pregnant women.

10 Aug, 2022 | 15:38h | UTC

Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library

Summary: Does using low-sodium salt substitutes (LSSS) instead of regular salt reduce blood pressure and heart disease risks, and is it safe? – Cochrane Library

Related:

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 


M-A | Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes.

29 Jul, 2022 | 12:37h | UTC

Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis – The Lancet Diabetes & Endocrinology

Commentaries:

No justification for bespoke antihypertensive intervention in type 2 diabetes – medwire News

Blood pressure control according to type 2 diabetes status – The Lancet Diabetes & Endocrinology (free registration required)

 

Commentary on Twitter

 


Systematic Review | Antiplatelet agents and anticoagulants for hypertension.

29 Jul, 2022 | 12:29h | UTC

Antiplatelet agents and anticoagulants for hypertension – Cochrane Library

Summary: Antiplatelet agents and anticoagulants for high blood pressure – Cochrane Library

 

Commentary on Twitter

 


Practical Guide | Antihypertensive deprescribing in older adults.

27 Jul, 2022 | 12:23h | UTC

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

 


Cohort Study | Markers of focal and diffuse nonischemic myocardial fibrosis are associated with adverse cardiac remodeling and prognosis in patients with hypertension.

26 Jul, 2022 | 11:46h | UTC

Markers of Focal and Diffuse Nonischemic Myocardial Fibrosis Are Associated With Adverse Cardiac Remodeling and Prognosis in Patients With Hypertension: The REMODEL Study – Hypertension

Commentary: Heart muscle scarring found in patients with hypertension are associated with worse outcomes – SingHealth

 


Cross Sectional Study | Variation in population attributable fraction of dementia associated with potentially modifiable risk factors by race and ethnicity in the US.

19 Jul, 2022 | 13:08h | UTC

Variation in Population Attributable Fraction of Dementia Associated With Potentially Modifiable Risk Factors by Race and Ethnicity in the US – JAMA Network Open

Commentaries:

12 Risk Factors Linked to Dementia Could Be Modified, Reduce US Cases by 400,000 – HCP Live

Hypertension, obesity, physical inactivity among highest risk factors for dementia – Healio

 

Commentary on Twitter

 


RCT | Effects of cuisine-based Chinese heart-healthy diet in lowering blood pressure among adults in China.

13 Jul, 2022 | 11:29h | UTC

Effects of Cuisine-Based Chinese Heart-Healthy Diet in Lowering Blood Pressure Among Adults in China: Multicenter, Single-Blind, Randomized, Parallel Controlled Feeding Trial – Circulation

News Release: Heart-healthy, lower sodium version of traditional Chinese cuisine lowered blood pressure – American Heart Association

Commentary: Modified Chinese Food Diet Lowers BP in Hypertensive Adults – HealthDay

 


Cohort Study | Adding salt to foods and hazard of premature mortality.

11 Jul, 2022 | 12:35h | UTC

Adding salt to foods and hazard of premature mortality – European Heart Journal (free for a limited period)

Editorial: Salt: the sweet spot?

 


M-A | Associations of thiazide use with skin cancers.

8 Jul, 2022 | 11:55h | UTC

Associations of thiazide use with skin cancers: a systematic review and meta-analysis – BMC Medicine

Related:

Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study – Canadian Medical Association Journal

Association of Hydrochlorothiazide Use and Risk of Malignant Melanoma – JAMA Internal Medicine

Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark – Journal of the American Academy of Dermatology

 


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