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Chest Medicine

What we know about Covid-19 reinfection so far

20 Jan, 2021 | 01:52h | UTC

What we know about covid-19 reinfection so far – The BMJ

 

Commentary on Twitter

 


Study: Household transmission of SARS-CoV-2 and risk factors for susceptibility and infectivity

20 Jan, 2021 | 01:49h | UTC

Household transmission of SARS-CoV-2 and risk factors for susceptibility and infectivity in Wuhan: a retrospective observational study – The Lancet Infectious Diseases

Related Report: SARS-CoV-2 setting-specific transmission rates. Households showed the highest transmission rates (21.1%). Asymptomatic infections do occur but much less efficiently than symptomatic infection

 

Commentary on Twitter

 


Systematic review on prophylaxis for COVID-19: Hydroxychloroquine does not work, little evidence regarding other drugs

20 Jan, 2021 | 01:38h | UTC

Prophylaxis for COVID-19: a systematic review – Clinical Microbiology and Infection

 


USPSTF Statement: Interventions for tobacco smoking cessation in adults

20 Jan, 2021 | 01:32h | UTC

Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons – U.S. Preventive Services Task Force

Editorial: A Comprehensive Approach to Increase Adult Tobacco Cessation – JAMA

Author Interview: USPSTF Recommendation: Tobacco Cessation in Adults

JAMA Patient Page: Interventions to Promote Tobacco Cessation

 


Guideline synopsis: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults

20 Jan, 2021 | 01:31h | UTC

Initiating Pharmacologic Treatment in Tobacco-Dependent Adults – JAMA (free for a limited period)

Author Interview: Pharmacologic Management of Tobacco Cessation

Original Guideline: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine

 


Evidence summary and clinical decision algorithm to guide clinicians in the care of the hypoxemic, non-intubated patients with suspected Covid-19

19 Jan, 2021 | 01:57h | UTC

Knowledge translation tools to guide care of non-intubated patients with acute respiratory illness during the COVID-19 Pandemic – Critical Care

 


Meta-analysis: Corticosteroid use in COVID-19 patients

19 Jan, 2021 | 01:56h | UTC

Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes – Critical Care

Related meta-analysis: Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials – Journal of Cardiothoracic and Vascular Anesthesia

 


IDSA: COVID-19 Diagnostic Guidelines Updates

19 Jan, 2021 | 01:54h | UTC

COVID-19 Diagnostic Guidelines Updates (Jan. 16, 2021) – Infectious Diseases Society of America

 


New calculator identifies COVID-19 patients at highest risk of deterioration

19 Jan, 2021 | 01:52h | UTC

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study – The Lancet Respiratory Medicine

Commentaries: Improving clinical management of COVID-19: the role of prediction models – The Lancet Respiratory Medicine

Tool identifies COVID-19 patients at highest risk of deterioration – UK Research and Innovation

See calculator: 4C Mortality & 4C Deterioration

 

Commentary on Twitter

 


Covid-19: What new variants are emerging and how are they being investigated?

19 Jan, 2021 | 01:51h | UTC

Covid-19: What new variants are emerging and how are they being investigated? – The BMJ

 


Meta-analysis: saliva and nasopharyngeal swab nucleic acid amplification have similar diagnostic accuracy for the detection of SARS-CoV-2

19 Jan, 2021 | 01:46h | UTC

Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis – JAMA Internal Medicine

Related: The Sensitivity and Costs of Testing for SARS-CoV-2 Infection With Saliva Versus Nasopharyngeal Swabs: A Systematic Review and Meta-analysis – Annals of Internal Medicine

 


RECOVERY trial: No Benefit from convalescent plasma in hospitalized patients with Covid-19

17 Jan, 2021 | 22:26h | UTC

RECOVERY trial closes recruitment to convalescent plasma treatment for patients hospitalised with COVID-19

Commentary: Covid: ‘Convalescent plasma no benefit to hospital patients’ – BBC

 


Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination

17 Jan, 2021 | 22:21h | UTC

Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination – The BMJ

See also: Covid-19 vaccination associated with adverse drug reactions in elderly people who are frail

 


Herd immunity by infection is not an option

17 Jan, 2021 | 22:16h | UTC

Herd immunity by infection is not an option – Science

 


CDC Study: Performance of an antigen-based test for asymptomatic and symptomatic SARS-CoV-2

17 Jan, 2021 | 22:10h | UTC

Performance of an Antigen-Based Test for Asymptomatic and Symptomatic SARS-CoV-2 Testing at Two University Campuses — Wisconsin, September–October 2020 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

 


Meta-analysis: Prophylactic macrolides beneficial for patients with COPD with frequent exacerbations

17 Jan, 2021 | 22:09h | UTC

Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta‐analysis – Cochrane Library

Summary: Prophylactic antibiotics for people with COPD – Cochrane Library

 


Position paper: Chest CT diagnosis and clinical management of drug-related pneumonitis in patients receiving molecular targeting agents and immune checkpoint inhibitors

17 Jan, 2021 | 22:07h | UTC

Chest CT Diagnosis and Clinical Management of Drug-related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper from the Fleischner Society – Radiology

 


Randomized trial: In patients hospitalized with community-acquired pneumonia, adjunctive oral dexamethasone reduced the length of stay and ICU admissions, with no difference in mortality rates

17 Jan, 2021 | 21:58h | UTC

Adjunctive treatment with oral dexamethasone in non-ICU patients hospitalised with community-acquired pneumonia: A randomised clinical trial – European Respiratory Journal (link to abstract – $ for full-text)

 


Study: Vaping combined with smoking may be as harmful as smoking cigarettes alone

17 Jan, 2021 | 21:53h | UTC

Association of Cigarette and Electronic Cigarette Use Patterns With Levels of Inflammatory and Oxidative Stress Biomarkers Among US Adults: Population Assessment of Tobacco and Health Study – Circulation

Commentaries: Vaping combined with smoking is likely as harmful as smoking cigarettes alone, study finds – American Heart Association AND CVD Biomarker Levels Up for Dual Use of E-Cigarettes, Cigarettes – Physician’s Weekly

 


Randomized trial: Inhaled Treprostinil in pulmonary hypertension due to interstitial lung disease

17 Jan, 2021 | 21:47h | UTC

Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease – New England Journal of Medicine

Commentaries: Inhaled Treprostinil Beneficial in Pulmonary Hypertension – HealthDay

 

Commentary on Twitter

 


Meta-analysis: Safety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation

17 Jan, 2021 | 21:42h | UTC

Safety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation: a systematic review and meta-analysis of randomized trials – CHEST (link to abstract – $ for full-text)

 


[Preprint] Past COVID-19 infection provides some immunity but people may still carry and transmit virus

15 Jan, 2021 | 09:02h | UTC

Past COVID-19 infection provides some immunity but people may still carry and transmit virus – Public Health England

See also: Covid-19: Past infection provides 83% protection for five months but may not stop transmission, study finds – The BMJ AND COVID reinfections are unusual — but could still help the virus to spread – Nature AND COVID-19 infection gives some immunity, but virus can still be spread, study finds – Reuters AND Expert reaction to a preprint from the SIREN study looking at SARS-CoV-2 infection rates in antibody positive healthcare workers – Science Media Centre

 


Observational study: Among patients hospitalized with Covid-19 not receiving mechanical ventilation, transfusion of plasma with higher anti–SARS-CoV-2 IgG antibody levels is linked to lower risk of death than transfusion of plasma with lower antibody levels

15 Jan, 2021 | 08:59h | UTC

Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19 – New England Journal of Medicine

Editorial: (A Little) Clarity on Convalescent Plasma for Covid-19 – New England Journal of Medicine

Commentaries: Expert reaction to study looking at convalescent plasma antibody levels and risk of death from COVID-19 – Science Media Centre AND Antibody-rich convalescent plasma may lower risk of COVID death – CIDRAP

 


Opinion: RCTs don’t justify using convalescent plasma or antibody cocktails

15 Jan, 2021 | 08:58h | UTC

RCTs don’t justify using convalescent plasma or antibody cocktails – PulmCrit

 


NIH Guideline Statement: “there are insufficient data to recommend either for or against the use of ivermectin for the treatment of COVID-19”

15 Jan, 2021 | 08:53h | UTC

The COVID-19 Treatment Guidelines Panel’s Statement on the Use of Ivermectin for the Treatment of COVID-19 – National Institutes of Health

 


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