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Chest Medicine

Series | Sleep and sleep disorders.

23 Sep, 2022 | 13:13h | UTC

Homepage: Sleep and sleep disorders (free registration required for all articles)

Editorial: Waking up to the importance of sleep

Series:

Understanding and approaching excessive daytime sleepiness

Insomnia

Circadian rhythms and disorders of the timing of sleep

Sleep function: an evolutionary perspective

Commentaries:

How and why do human beings sleep?

Social determinants and health disparities affecting sleep

 


Long covid—an update for primary care.

23 Sep, 2022 | 13:10h | UTC

Long covid—an update for primary care – The BMJ

 


RCT | Operative vs. nonoperative treatment of acute unstable chest wall injuries.

22 Sep, 2022 | 13:13h | UTC

Operative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Invited commentary: Operative Treatment of Acute Unstable Chest Wall Injuries—Let Us All Take a Deep Breath – JAMA Surgery (free for a limited period)

Author Interview: Operative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries – JAMA

Related:

Surgical management of rib fractures after blunt trauma: a systematic review and meta-analysis of randomised controlled trials – Annals of The Royal College of Surgeons of England

RCT | Rib fixation is not beneficial for non–ventilator-dependent chest wall injuries.

 

Commentary on Twitter

 


RCT | Helmet noninvasive ventilation no better than usual respiratory support for acute hypoxemic respiratory failure due to COVID-19.

22 Sep, 2022 | 13:11h | UTC

Effect of Helmet Noninvasive Ventilation vs Usual Respiratory Support on Mortality Among Patients With Acute Hypoxemic Respiratory Failure Due to COVID-19: The HELMET-COVID Randomized Clinical Trial – JAMA

 

Commentary on Twitter

 


Understanding post-COVID-19 interstitial lung disease: a new fibroinflammatory disease entity.

22 Sep, 2022 | 13:09h | UTC

Understanding post-COVID-19 interstitial lung disease (ILD): a new fibroinflammatory disease entity – Intensive Care Medicine

 

Commentary on Twitter

 


Pulmonary artery denervation for pulmonary arterial hypertension: a sham-controlled randomized trial.

21 Sep, 2022 | 13:21h | UTC

Pulmonary Artery Denervation for Pulmonary Arterial Hypertension: A Sham-Controlled Randomized Trial – JACC: Cardiovascular Interventions

Commentaries:

Pulmonary Artery Denervation in Idiopathic PAH Ups 6-Minute Walk Test – TCTMD

Pulmonary Artery Denervation for Pulmonary Arterial Hypertension – PADN-CFDA – American College of Cardiology

 

Commentary on Twitter

 


ISHLT consensus statement | Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery.

21 Sep, 2022 | 13:15h | UTC

ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery – the Journal of Heart and Lung Transplantation

Related Guideline: Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement – British Journal of Anaesthesia

 


The Lancet Commission on lessons for the future from the COVID-19 pandemic – “a massive global failure.”

16 Sep, 2022 | 13:03h | UTC

Homepage: The Lancet COVID-19 Commission

The Lancet Commission on lessons for the future from the COVID-19 pandemic

Editorial: COVID-19: the case for prosociality

News Release: New report details “massive global failures” of COVID-19 response, calls for improved multilateral cooperation to end pandemic and effectively manage future global health threats – The Lancet

Infographic: COVID-19 response: a massive global failure

Commentaries:

WHO responds to The Lancet COVID-19 Commission – World Health Organization

Covid-19: Commission describes “massive global failures” of pandemic response – The BMJ

Covid-19 death toll is a tragedy and ‘massive global failure at multiple levels,’ Lancet commission says – CNN

Lancet Commission on COVID-19 response: ‘Massive global failure’ – CIDRAP

 


The Lancet Commission | Towards the elimination of chronic obstructive pulmonary disease.

16 Sep, 2022 | 13:02h | UTC

Homepage: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission – The Lancet

Commission: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

Editorial: COPD: from an end-stage disease to lifelong lung health

Invited Commentary: Classification of COPD: fostering prevention and precision medicine in the Lancet Commission on COPD

Commentary: Proposed classification of COPD according to major risk factors – News Medical

 


M-A of randomized trials | In patients hospitalized with community-acquired pneumonia, corticosteroids reduce the need for mechanical ventilation without significant effects on mortality, treatment failure, or adverse events.

14 Sep, 2022 | 13:16h | UTC

Effect of corticosteroids on mortality and clinical cure in community-acquired pneumonia: A systematic review, meta-analysis, and meta-regression of randomized control trials – CHEST Journal (link to abstract – $ for full-text)

Related: Corticosteroids for CAP, influenza and COVID-19: when, how and benefits or harm? – European Respiratory Review

 


RCT | Dexamethasone is not effective for the treatment of dyspnea in patients with cancer and increases the risk of adverse events.

13 Sep, 2022 | 13:22h | UTC

Effect of dexamethasone on dyspnoea in patients with cancer (ABCD): a parallel-group, double-blind, randomised, controlled trial – The Lancet Oncology (free for a limited period)

 

Commentary on Twitter

 


RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.

13 Sep, 2022 | 13:19h | UTC

Influenza vaccination strategy in acute coronary syndromes: the VIP-ACS trial – European Heart Journal

 

Commentary on Twitter

 


RCT | Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19.

13 Sep, 2022 | 13:16h | UTC

Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial – The Lancet Respiratory Medicine

 

Commentaries on Twitter

 


RCT | Dipeptidyl peptidase-1 inhibition does not improve outcomes in patients hospitalized with COVID-19.

13 Sep, 2022 | 13:15h | UTC

Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial – The Lancet Respiratory Medicine

 

Commentary on Twitter

 


M-A of randomized trials | High-flow nasal cannula oxygen therapy vs. non-invasive ventilation for patients with acute exacerbation of COPD after extubation.

13 Sep, 2022 | 13:00h | UTC

High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation for AECOPD Patients After Extubation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – International Journal of Chronic Obstructive Pulmonary Disease

 


Two large clinical trials showed Vitamin D supplements do not reduce the risk of Covid-19.

11 Sep, 2022 | 22:56h | UTC

Study 1: Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: phase 3 randomised controlled trial (CORONAVIT) – The BMJ

Study 2: Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial – The BMJ

Editorial: Can vitamin D protect against covid-19? – The BMJ

News Release: No link between vitamin D supplements and reduced risk of covid-19 – BMJ Newsroom

 


Extracorporeal membrane oxygenation during respiratory pandemics: past, present, and future.

11 Sep, 2022 | 22:53h | UTC

Extracorporeal Membrane Oxygenation during Respiratory Pandemics: Past, Present, and Future – American Journal of Respiratory and Critical Care Medicine

 


International consensus statement on obstructive sleep apnea.

8 Sep, 2022 | 14:41h | UTC

International consensus statement on obstructive sleep apnea – Allergy & Rhinology (PDF)

 


Systematic Review | Chest physiotherapy for pneumonia in adults.

8 Sep, 2022 | 14:36h | UTC

Chest physiotherapy for pneumonia in adults – Cochrane Library

Summary: Chest physiotherapy for pneumonia in adults – Cochrane Library

 


The Lancet Series | Acute Respiratory Distress Syndrome 2022.

7 Sep, 2022 | 12:37h | UTC

Homepage: Acute Respiratory Distress Syndrome 2022 – The Lancet

Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes

Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

Opportunities for improved clinical trial designs in acute respiratory distress syndrome

Addressing the inequity of acute respiratory distress syndrome

 


Review | Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome.

6 Sep, 2022 | 14:42h | UTC

Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome – The Lancet Respiratory Medicine

 


Systematic Review | Probiotics for preventing acute upper respiratory tract infections.

6 Sep, 2022 | 14:40h | UTC

Probiotics for preventing acute upper respiratory tract infections – Cochrane Library

 

Commentary on Twitter

 


Study suggests AI improves chest X-ray interpretation.

6 Sep, 2022 | 14:38h | UTC

Commentary: Study Suggests AI Improves Chest X-Ray Interpretation – Diagnostic Imaging

Original Study: Association of Artificial Intelligence–Aided Chest Radiograph Interpretation With Reader Performance and Efficiency – JAMA Network Open

 

Commentary on Twitter

 


RCT | Anatomical segmentectomy vs. standard lobectomy for non-small cell lung cancer up to 2 cm.

6 Sep, 2022 | 14:28h | UTC

Survival outcomes in a prospective randomized multicenter Phase III trial comparing patients undergoing anatomical segmentectomy versus standard lobectomy for non-small cell lung cancer up to 2 cm – Lung Cancer

Related:

A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer – The Korean Journal of Thoracic and Cardiovascular Surgery

 


Phase 2 RCT | Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease.

6 Sep, 2022 | 14:22h | UTC

Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study – The Lancet Respiratory Medicine

 

Commentary on Twitter

 


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